Pathogens | Free Full-Text | High Predictive Value of the Soluble ZEBRA Antigen (Epstein-Barr Virus Trans-Activator Zta) in...
Z EBV replication activator) protein is the major transcription factor of EBV, expressed upon EBV lytic cycle activation. An ... High Predictive Value of the Soluble ZEBRA Antigen (Epstein-Barr Virus Trans-Activator Zta) in Transplant Patients with PTLD by ... "High Predictive Value of the Soluble ZEBRA Antigen (Epstein-Barr Virus Trans-Activator Zta) in Transplant Patients with PTLD" ... "High Predictive Value of the Soluble ZEBRA Antigen (Epstein-Barr Virus Trans-Activator Zta) in Transplant Patients with PTLD" ...
Open Research: Development of transactivator system for rice and its application for studies of floral development
... and the expression patterns were proven to be due to the activity of the GAL4/VP16 transcriptional activator. Most of the TAFET ... Development of transactivator system for rice and its application for studies of floral development. Download (6.39 MB) ... Home » ANU Research » ANU Theses » Open Access Theses » Development of transactivator system for rice and its application for ... Two different B-glucuronidase reporter gene cassettes (GUS and GUSPlus) and two GAL4/VP16 transactivator cassettes (with and ...
The BOB.1 / OBF.1 co-activator is essential for octamer-dependent transcription in B cells
... is a B cell-specific co-activator of the Oct1 and Oct2 transcription factors. It is involved in mediating the transcriptional ... Trans-Activators / physiology* * Transcription, Genetic / immunology Substances * Pou2af1 protein, mouse * Trans-Activators ... The BOB.1 / OBF.1 co-activator is essential for octamer-dependent transcription in B cells Eur J Immunol. 2000 Feb;30(2):458-69 ... The BOB.1 / OBF.1 / OCA-B protein (henceforth designated as BOB.1 / OBF.1) is a B cell-specific co-activator of the Oct1 and ...
Functional characterization of transcription regulators that interact with the electrophile response element
Trans-Activators / chemistry * Trans-Activators / genetics * Trans-Activators / metabolism * Transcription Factors / metabolism ...
Tat (HIV) - Wikipedia
Tat stands for "Trans-Activator of Transcription". The protein consists of between 86 and 101 amino acids depending on the ... "Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein". Cell. 55 (6 ... Tat acts by binding to an RNA stem-loop structure, the trans-activation response element (TAR), found at the 5′ ends of nascent ... The basic region is involved in RNA (TAR, trans-activation response element) binding and Tat proteins thus belong to the family ...
A "no-hybrids" screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast. -...
Drosophila p53 to demonstrate that the system can detect evolutionarily distant p53 homologues based on their transactivator ... screen in the fission yeast Schizosaccharomyces pombe based on the transcription transactivator activity of human p53. The ... Trans-Activators, Tumor Suppressor Protein p53, Two-Hybrid System Techniques ... A "no-hybrids" screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast. ...
SMAD7 | Cancer Genetics Web
Biblio | Page 9 | Linus Pauling Institute | Oregon State University
Biblio | Page 9 | Linus Pauling Institute | Oregon State University
Advanced Search Results - Public Health Image Library(PHIL)
KEGG PATHWAY: hsa05152
STAT1; signal transducer and activator of transcription 1 [KO:K11220]. 4261 CIITA; class II major histocompatibility complex ... Regulation of MHC class II gene expression by the class II transactivator. ...
JCI - Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells. Genes Dev 1990. 4:1023-1034. View this article ... NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of ... These studies identified the nuclear respiratory factors-1 and -2 (NRF-1 and -2) as key transcriptional activators of nuclear ...
Status Epilepticus-Induced Somatostatinergic Hilar Interneuron Degeneration Is Regulated by Striatal Enriched Protein Tyrosine...
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Harris A. Gelbard, M.D., Ph.D. | UR Medicine
HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with ... HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis. ...
Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance | Biochemical Society...
The transcriptional transactivator NLRC5 is a critical regulator of MHC I expression. It forms a scaffold with DNA binding ... IRF2 has been shown to be a transcriptional activator of the CIITA-pIV promoter [100]. IRF2 loss is described in several ... IFNγ is a key regulator of MHC-I expression through JAK1/2 (janus kinase 1/2)-STAT1 (signal transducer and activator of ... Expression of MHC-II is controlled by the transcriptional master regulator class II transactivator (CIITA) [84]. The CIITA ...
rTg(tauP301L)4510 | ALZFORUM
... to an activator line expressing a tetracycline-controlled transactivator (tTA) under control of the CaMKIIα promoter. Bi- ... In addition, shrinkage of the dentate gyrus occurs in the CaMKIIα-tTA activator line, although it is not yet known whether this ... T2 mice were then crossed with the CaMKIIα-tTA activator line to create bi-transgenic mice (designated rT2/T2 when homozygous ... Genetic Background: Mixed: 129S6 (activator) X FVB (responder) Availability: 4510 responder line: The Jackson Lab: Stock# ...
hTERT-Immortalized Bone Mesenchymal Stromal Cells Expressing Rat Galanin via a Single Tetracycline-Inducible Lentivirus System
This system is less toxic than the rtTA since it does not have the transactivator VP16. In the present study, the inducibility ... dependent transcriptional activator and repressor co-expression system for the strong induction of transgene expression," ... the promoter is only active when the tTA or the rtTA transactivators bind the regulated promoter; the expression of the VP16 ... transactivators in the regulated cells can have several undesired consequences such as alteration of the promoter natural ...
NeuroD1 Monoclonal Antibody (4G12B4) (MA5-38581)
Protein Aliases: basic helix-loop-helix transcription factor; beta-cell E-box transactivator 2; BHF1; bHLHa3; Class A basic ... NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to ... RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA ...
Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3 | PLOS ONE
Thus, the ability for HER3 to function as a transcriptional co-activator may be dependent on specific C-terminal TADs. ... Inside the nucleus, HER family members (EGFR, HER2, and HER3) have been shown to function as co-transcriptional activators for ... Hirai H, Tani T, Kikyo N (2010) Structure and functions of powerful transactivators: VP16, MyoD and FoxA. The International ... To date, EGFR, HER2, and a nuclear variant of HER3 have been shown to function as co-transcriptional activators for cyclin D1 [ ...
Hui-Chen Lu - Publications
X-chromosome-inactivation - Research group/lab - Erasmus MC
The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing. Mol Cell 53: ... and indicated the presence of X-linked activators of XCI. The activity of these XCI-activators is counterbalanced by ... We identified X-encoded RNF12 as an activator of XCI. Rnf12 is located just 500 kb telomeric of Xist and encodes an E3 ... RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation. Cell 139: 999-1011.. Monkhorst K, Jonkers I, ...
Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. | Emmes
ZFIN Publication: Fekany et al., 1999
Drosophila Tcf and Groucho interact to repress Wingless signalling activity.
Recent insights into Protein Phosphatase 2A structure and regulation: the reasons why PP2A is no longer considered as a lazy...
The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase. J. Biol. Chem., 281(10), 6349- ... Indeed, PTPA (phosphotyrosyl phosphatase activator, newly renamed phosphatase two A phosphatase activator) can activate the ... Pro can exist in two conformations, cis and trans, in this motif. PP2A is considered as a major Pro-directed phosphatase which ... Studies of several PP2A substrates including Tau, Cdc25C, Myc and Raf1 substrates have lead to the hypothesis that a trans ...
ZFIN Publication: Otteson et al., 2005
SF's draft of strain details view - INFRAFRONTIER
Allele name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; targeted mutation 1, Shoumo ... Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator ... Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator ... Gene name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ...
KoreaMed
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome. ...
Duke Researchers Engineer RNA Hairpin Structures to Improve CRISPR Specificity | GenomeWeb
"Transfecting sgRNA variants and a dCas9-P300 transactivator into human cells, we observed that hp-sgRNAs can tune gene ... they decided to utilize nuclease-inactive dCas9-based transcriptional activators where endogenous gene activation can serve as ... the team demonstrated that designed hp-sgRNAs can tune the activity of a transactivator based on Cas9 from Streptococcus ...