A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis
Phytocannabinoids like ∆(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD) show a beneficial effect on neuroinflammatory and neurodegenerative processes through cell membrane cannabinoid receptor (CBr)-dependent and -independent mechanisms. Natural and synthetic cannabinoids also target the nuclea …
Picornavirus Infections: Background, Pathophysiology, Epidemiology
Saffold virus - Wikipedia
The AMEDEO Literature Guide
Taconic Biosciences Implements Changes to its Animal Health Program | Taconic Biosciences
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
DeCS 2002 - Changed terms
Staphylococcus aureus Archives - Quip Labs
Center for Brain Immunology & Glia (BIG) - Research output
- Research Profiles at Washington University School of Medicine
Jiang, M., Wang, J., Fu, J., Du, L., Jeong, H., West, T., Xiang, L., Peng, Q., Hou, Z., Cai, H., Seredenina, T., Arbez, N., Zhu, S., Sommers, K., Qian, J., Zhang, J., Mori, S., Yang, X. W., Tamashiro, K. L. K., Aja, S., & 10 othersMoran, T. H., Luthi-Carter, R., Martin, B., Maudsley, S., Mattson, M. P., Cichewicz, R. H., Ross, C. A., Holtzman, D. M., Krainc, D. & Duan, W., Jan 2012, In: Nature medicine. 18, 1, p. 153-158 6 p.. Research output: Contribution to journal › Article › peer-review ...
Animal Health Monitoring Profiles | IDEXX BioAnalytics
EDx Testing Profiles | IDEXX BioAnalytics
A translatable molecular approach to determining CD8 T-cell epitopes in TMEV infection<...
Pesquisa | Portal Regional da BVS
The same cleavage pattern was observed during Theilovirus infection. The cleavage of MDA5 by Theilovirus protease impaired ATP ... Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene ... In this study, we describe a targeted cleavage events of MDA5 by the 3C protease from Theilovirus. Upon ectopic expression of ... When enzymatically inactive Theilovirus 3C protease was expressed, MDA5 cleavage was completely abrogated. Mass spectrometric ...
Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity. - Radcliffe...
教員情報 - 小室 晃彦 | 新潟薬科大学
The effect of B-cell depletion in the Theiler's model of multiple sclerosis. - Oxford Neuroscience
Hematopoietic cell activation in the subventricular zone after Theiler's virus infection. - Immunology
BACKGROUND: The periventricular subventricular zone (SVZ) contains stem cells and is an area of active neurogenesis and migration. Since inflammation can reduce neurogenesis, we tested whether Theilers murine encephalomyelitis virus (TMEV) induces inflammation and reduces neurogenesis in the SVZ. METHODS: We performed immmunohistochemistry for the hematopoietic cell marker CD45 throughout the central nervous system and then examined neuroblasts in the SVZ. RESULTS: CD45+ activation (inflammation) occurred early in the forebrain and preceded cerebellar and spinal cord inflammation. Inflammation in the brain was regionally stochastic except for the SVZ and surrounding periventricular regions where it was remarkably pronounced and consistent. In preclinical mice, SVZ neuroblasts emigrated into inflamed periventricular regions. The number of proliferating phoshpohistone3+ cells and Doublecortin+ (Dcx) SVZ neuroblasts was overall unaffected during the periods of greatest inflammation. However the number of
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