*  RCSB PDB for 1OHS
Crystal Structure of 5-3-Ketosteroid Isomerase Mutant Y14F/D38N from Pseudomonas Testosteroni Complexed with Androstanedione ... STEROID DELTA-ISOMERASE A, B, C, D 125 Comamonas testosteroni EC#: 5.3.3.1 IUBMB Mutation: Y14F, D38N, T83I Gene Name(s): ksi ... CRYSTAL STRUCTURE OF 5-3-KETOSTEROID ISOMERASE MUTANT Y14F/D38N FROM PSEUDOMONAS TESTOSTERONI COMPLEXED WITH ANDROSTANEDIONE. * ...
  http://www.rcsb.org/pdb/explore/biologyAndChemistry.do?structureId=1OHS
*  Steroid Delta-isomerase - Wikipedia
... steroid isomerase, Δ5-ketosteroid isomerase, Δ5(or Δ4)-3-keto steroid isomerase, Δ5-steroid isomerase, 3-oxosteroid isomerase, ... In enzymology, a steroid Δ5-isomerase (EC 5.3.3.1) is an enzyme that catalyzes the chemical reaction a 3-oxo-Δ5-steroid ⇌ {\ ... isomerase and 3α- and 3β-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot". The Journal of Steroid ... Δ5-3-keto steroid isomerase, and Δ5-3-oxosteroid isomerase. KSI has been studied extensively from the bacteria Comamonas ...
  https://en.wikipedia.org/wiki/Steroid_Delta-isomerase
*  Hsd3b7 (untagged) - Mouse hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 (Hsd3b7), transcript...
... and steroid delta-isomerase 7 (Hsd3b7), transcript variant 1, (10ug), 10 µg. ... Home » cDNA » Mouse cDNA » Hsd3b7 (untagged) - Mouse hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase ... MC212072 Hsd3b7 (untagged) - Mouse hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 (Hsd3b7), ... Properties for Hsd3b7 (untagged) - Mouse hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 (Hsd3b7 ...
  https://www.acris-antibodies.com/cdna/mouse-cdna/hsd3b7-untagged-mouse-hydroxy-delta-5-steroid-dehydrogenase-3-beta-and-steroid-delta-isomerase-7-hsd3b7-transcript-variant-1-10ug-mc212072.htm
*  Azasteroid - Wikipedia
DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase". Journal of Medicinal Chemistry. 37 (15): 2352-60. doi:10.1021 ... An azasteroid is a type of steroid derivative which has one of the carbon atoms in the steroid ring system replaced by a ... Potent dual inhibitors of human type 1 and 2 steroid 5.alpha.-reductase". Journal of Medicinal Chemistry. 36 (26): 4313-5. doi: ...
  https://en.wikipedia.org/wiki/Azasteroid
*  GSTA3 - Wikipedia
2005). "Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase ... Johansson AS, Mannervik B (2002). "Active-site residues governing high steroid isomerase activity in human glutathione ... a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones". J. Biol. Chem. 276 ( ... effects on xenobiotic metabolism and steroid biosynthesis". Pharmacogenetics. 14 (10): 657-63. doi:10.1097/00008571-200410000- ...
  https://en.wikipedia.org/wiki/GSTA3
*  RCSB PDB - 1OHS: CRYSTAL STRUCTURE OF 5-3-KETOSTEROID ISOMERASE MUTANT Y14F/D38N FROM PSEUDOMONAS TESTOSTERONI...
Crystal Structure of 5-3-Ketosteroid Isomerase Mutant Y14F/D38N from Pseudomonas Testosteroni Complexed with Androstanedione ... STEROID DELTA-ISOMERASE A, B, C, D 125 Comamonas testosteroni EC#: 5.3.3.1 IUBMB Mutation: Y14F, D38N, T83I Gene Name(s): ksi ... CRYSTAL STRUCTURE OF 5-3-KETOSTEROID ISOMERASE MUTANT Y14F/D38N FROM PSEUDOMONAS TESTOSTERONI COMPLEXED WITH ANDROSTANEDIONE. * ...
  http://www.rcsb.org/pdb/explore/litView.do?structureId=1OHS
*  Drug Information Portal - U.S. National Library of Medicine - Quick Access to Quality Drug Information
A sigma receptor antagonist and steroid isomerase inhibitor with immunosuppressive and anti-inflammatory activities. ...
  https://druginfo.nlm.nih.gov/drugportal/rn/132173-07-0
*  Hsd3b2 - 3 beta-hydroxysteroid dehydrogenase/Delta 5--|4-isomerase type 2 - Mus musculus (Mouse) - Hsd3b2 gene & protein
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. ... ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. ... A 3-beta-hydroxy-Delta5-steroid + NAD+ = a 3-oxo-Delta5-steroid + NADH. ... A 3-oxo-Delta5-steroid = a 3-oxo-Delta4-steroid. ... steroid delta-isomerase activity Source: UniProtKB-EC. Complete ...
  http://www.uniprot.org/uniprot/P26149
*  Deoxycholic Acid - DrugBank
Steroid delta-isomerase activity. Specific Function. Not Available. Gene Name. ksi. Uniprot ID. P07445. Uniprot Name. Steroid ... Steroids and steroid derivatives. Sub Class. Bile acids, alcohols and derivatives. Direct Parent. Dihydroxy bile acids, ...
  https://www.drugbank.ca/drugs/DB03619
*  Sequence Similarity - 1DMM: CRYSTAL STRUCTURES OF MUTANT ENZYMES Y57F OF KETOSTEROID ISOMERASE FROM PSEUDOMONAS...
... involving a tyrosine triad in the active site to the structure and function of a highly proficient ketosteroid isomerase from ... STEROID DELTA-ISOMERASE protein, length: 131 (BLAST) Sequence Similarity Cutoff. Rank. Chains in Cluster. Cluster ID / Name. ... CRYSTAL STRUCTURES OF MUTANT ENZYMES Y57F OF KETOSTEROID ISOMERASE FROM PSEUDOMONAS PUTIDA BIOTYPE B. ...
  http://www.rcsb.org/pdb/explore/sequenceCluster.do?structureId=1DMM
*  Sequence Similarity - 1GS3: High resolution crystal structure of PI delta-5-3-Ketosteroid Isomerase mutants Y30F/Y55F...
Contribution of a Low-Barrier Hydrogen Bond to Catalysis by Delta-5-3-Ketosteroid Isomerase is not Extremely High Compared to ... STEROID DELTA-ISOMERASE protein, length: 131 (BLAST) Sequence Similarity Cutoff. Rank. Chains in Cluster. Cluster ID / Name. ... High resolution crystal structure of PI delta-5-3-Ketosteroid Isomerase mutants Y30F/Y55F/Y115F/D38N (Y32F/Y57F/Y119F/D40N, PI ...
  http://www.rcsb.org/pdb/explore/sequenceCluster.do?structureId=1GS3
*  KEGG ENZYME: 1.1.1.145
3beta-hydroxy steroid dehydrogenase/isomerase;. 3beta-hydroxy-Delta5-C27-steroid dehydrogenase/isomerase;. 3beta-hydroxy-Delta5 ... steroid oxidoreductase;. 3beta-hydroxy-5-ene-steroid oxidoreductase;. steroid-Delta5-3beta-ol dehydrogenase;. 3beta-HSDH;. 5- ... EC 5.3.3.1, steroid Delta-isomerase). Substrates include dehydroepiandrosterone (which is converted into androst-5-ene-3,17- ... a 3beta-hydroxy-Delta5-steroid + NAD+ = a 3-oxo-Delta5-steroid + NADH + H+ [RN:R03176]. ...
  http://www.genome.jp/dbget-bin/www_bget?ec:1.1.1.145
*  HSD3B2 - Wikipedia
... isomerase type II or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2. It is expressed principally ... HSD3B2 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2". Pelletier G, Dupont E, Simard J, Luu-The ... 1991). "Regional chromosomal assignment of human 3-beta-hydroxy-5-ene steroid dehydrogenase to 1p13.1 by non-isotopic in situ ... 1992). "Structure of the human type II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) gene: adrenal ...
  https://en.wikipedia.org/wiki/HSD3B2
*  KEGG PATHWAY: xtr00120
hsd3b7; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [KO:K12408] [EC:1.1.1.181] ... Bile acids are steroid carboxylic acids derived from cholesterol in vertebrates. The primary bile acids, cholic acid and ... The bile acid synthetic gene 3beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic ...
  http://www.genome.jp/dbget-bin/www_bget?pathway+xtr00120
*  Most recent papers with the keyword Detox | Read by QxMD
... www.readbyqxmd.com/read/29180167/characterization-of-equine-gst-a3-3-as-a-steroid-isomerase ... Thus, a member of the Alpha class GSTs in pig and human tissues is involved in steroid hormone biosynthesis, catalyzing the ...
  https://www.readbyqxmd.com/keyword/4037
*  Molecular Characterization and Expression Analysis of a Glutathione S-Transferase cDNA from Abalone (Haliotis discus hannai) |...
Johansson, A.S. and Mannervik, B. (2002) Active-site residues governing high steroid isomerase activity in human glutathione ... Polekhina, G., Board, P.G., Blackburn, A.C. and Parker, M.W. (2001) Crystal structure of maleylacetoacetate isomerase/ ...
  http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=GPRHB@_2014_v30n4_399
*  Search Molecular Signatures of Dietary Restriction
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Gene. Mus musculus. Under-expressed. ... protein disulfide isomerase associated 3 Gene. Mus musculus. Under-expressed. *GA:Sc ...
  http://genomics.senescence.info/diet/search_exp.php?tbl=2&show=&sort=1&page=3
*  HSD3B1 - Wikipedia
... isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1. While it can carry out the ... HSD3B1 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1". Researchers Identify Genetic Mutation ... 1991). "Regional chromosomal assignment of human 3-beta-hydroxy-5-ene steroid dehydrogenase to 1p13.1 by non-isotopic in situ ... 1989). "Full length cDNA structure and deduced amino acid sequence of human 3 beta-hydroxy-5-ene steroid dehydrogenase". Mol. ...
  https://en.wikipedia.org/wiki/HSD3B1
*  Patent US6139832 - Leukocyte adhesion inhibitor-1 (LAI-1) Polypeptides - Google Patents
... delta-5-steroid isomerase, yeast-alcohol dehydrogenase, alpha-glycerol phosphate dehydrogenase, triose phosphate isomerase, ...
  http://www.google.com/patents/US6139832?dq=6650327
*  Patent US5846763 - DNA encoding tumor necrosis factor stimulated gene 6 (TSG-6) - Google Patents
... delta-5-steroid isomerase, yeast alcohol dehydrogenase, alpha-glycerophosphate dehydrogenase, triose phosphate isomerase, ...
  http://www.google.com/patents/US5846763?dq=7,603,356
*  Patent US20020031508 - Methods for diagnosing and treating hemostatic disorders by modulating P ... - Google Patents
... delta-5-steroid isomerase, yeast alcohol dehydrogenase, alpha-glycerophosphate, dehydrogenase, triose phosphate isomerase, ...
  http://www.google.com/patents/US20020031508?dq=6,460,050
*  List of MeSH codes (D08) - Wikipedia
... steroid isomerases MeSH D08.811.399.475.800 --- sulfur-sulfur bond isomerases MeSH D08.811.399.475.800.550 --- protein ... steroid 11-beta-hydroxylase MeSH D08.244.453.915.730 --- steroid 12-alpha-hydroxylase MeSH D08.244.453.915.737 --- steroid 16- ... steroid 11-beta-hydroxylase MeSH D08.811.682.690.708.170.915.730 --- steroid 12-alpha-hydroxylase MeSH D08.811.682.690.708.170. ... triose-phosphate isomerase MeSH D08.811.399.475.400 --- carbon-carbon double bond isomerases MeSH D08.811.399.475.400.700 --- ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D08)
*  Patente US5302384 - Endothelial-derived II-8 adhesion inhibitor - Google Patentes
... delta-V-steroid isomerase, yeast alcohol dehydrogenase, alpha-glycerophosphate dehydrogenase, triose phosphate isomerase, ...
  http://www.google.es/patents/US5302384?dq=flatulence
*  Patente US20070270506 - Novel human kinases and polynucleotides encoding the same, and uses thereof - Google Patentes
... delta-5-steroid isomerase, yeast alcohol dehydrogenase, alpha-glycerophosphate, dehydrogenase, triose phosphate isomerase, ...
  http://www.google.es/patents/US20070270506?dq=flatulence