Sp4 transcription factor - Wikipedia
Transcription factor Sp4 is a protein that in humans is encoded by the SP4 gene. Sp4 transcription factor has been shown to ... "Entrez Gene: SP4 Sp4 transcription factor". Rotheneder H, Geymayer S, Haidweger E (November 1999). "Transcription factors of ... Kalff-Suske M, Kunz J, Grzeschik KH, Suske G (April 1995). "Human Sp4 transcription factor gene (SP4) maps to chromosome 7p15 ... Sp4+Transcription+Factor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short ...
Sp4 Transcription Factor | Profiles RNS
"Sp4 Transcription Factor" by people in this website by year, and whether "Sp4 Transcription Factor" was a major or minor topic ... "Sp4 Transcription Factor" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Sp4 Transcription Factor" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Sp4 Transcription Factor". ...
SP2 Sp2 transcription factor [Homo sapiens (human)] - Gene - NCBI
O-GlcNAc modification of Sp3 and Sp4, but not Sp2 transcription factors negatively regulates their transcriptional activities. ... Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro. Title: Transcription Factor SP2 Regulates Ski ... SP2 Sp2 transcription factor [Homo sapiens] SP2 Sp2 transcription factor [Homo sapiens]. Gene ID:6668 ... Title: O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities. ...
PDF) Isolated mitral valve prolapse is an independent predictor of aortic root size in a general population
... transcription factor Sp4 gene (A80807T, rs1011168), genes of matrix metalloproteinases type 3 (5A/6A) and type 9 (8202 A/G) ... Most significant risk factors for extension/aneurysm of the aorta were pathology of vertebral arteries, common risk factors ( ... Transforming growth factor-β₁ and β₂ serum levels were elevated in patients with classic prolapse as compared with the control ... Objectives: There is no reliable evidence on the role of genetics or pathophysiological factors in this correlation, and the ...
Belen Ramos Josémaria - Fingerprint - Universitat Autònoma de Barcelona Research Portal
Genome-wide Association Study Of Recurrent Early-onset Major Depressive Disorder | Academic Commons
... a brain-specific transcription factor. Larger samples will be required to confirm the hypothesis of association between MDD ( ... for association of MDD to SNPs within SP4, ... for association of MDD to SNPs within SP4, a brain-specific ... transcription factor. Larger samples will be required to confirm the hypothesis of association between MDD (and particularly ...
Exosomal microRNAs are novel circulating biomarkers in cigarette,waterpipe smokers, E-cigarette users and dual smokers |...
The transcription factor related EGR1, SP1, SP4 and POU2F1 were highly significant in all four groups while ZFP161 in only NS ... The transcription factor related EGR1, SP1, SP4 and POU2F1 were highly significant in all four groups while ZFP161 in only NS ... These are lipid vesicles carrying various types of biological materials such as proteins, RNAs, DNAs, transcription factors, ... The two molecular functions with highly significant values related to transcription factor activity and extracellular matrix ...
SP4 and ATXN7L1 - Wiki-MPM
Sp transcription factor family and its role in cancer<...
Sp1-Sp4 proteins regulate expression of multiple genes in normal tissues and tumours. There is growing evidence that some Sp ... Safe, S., & Abdelrahim, M. (2005). Sp transcription factor family and its role in cancer. European Journal of Cancer, 41(16), ... Sp transcription factor family and its role in cancer. In: European Journal of Cancer. 2005 ; Vol. 41, No. 16. pp. 2438-2448. ... Safe, S & Abdelrahim, M 2005, Sp transcription factor family and its role in cancer, European Journal of Cancer, vol. 41, no ...
Gene Set - mRNA KAT5 22196727
THAKAR PBMC INACTIVATED INFLUENZA AGE 70PLS NONRESPONDER 2DY UP
SP4. 6671. SP4. Sp4 transcription factor [Source:HGN.... SRPRB. 58477. SRPRB. SRP receptor subunit beta [Source:HG.... ... TFT: Transcription Factor Targets TFT:GTRD: GTRD TFT:TFT_LEGACY: TFT_Legacy C4: Computational 3CA: Curated Cancer Cell Atlas ... and implicate changes in mitochondrial biogenesis and function as a critical factor in human vaccine responsiveness.. ...
GSE17721 LPS VS PAM3CSK4 12H BMDC UP
Estimating the effects of transcription factors binding and histone modifications on gene expression levels in human cells |...
But the higher positive correlation between ATF2 and SP4 (between USF1 and USF2) is cell line specific. Besides, based on the ... transcription start site; RPKM, reads per kilobase of exon model per million mapped reads; TFAS, Transcription factors ... Transcription factors binding signal. The DNA regions flanking the TSS (-10~10kb) of all RefSeq genes are separated into 100 ... ChIP-Seq of transcription factors predicts absolute and differential gene expression in embryonic stem cells. Proc Natl Acad ...
Pesquisa | Portal Regional da BVS
Sp4 is a transcription factor for which gene expression is restricted to neuronal cells in the brain. Our previous studies ... Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. ... such as transcription factor Nurr1 and DA-synthesizing enzyme tyrosine hydroxylase (TH), and the concomitant effects on motor ... RESULTS: Restoration of Sp4 in forebrain excitatory neurons did not rescue deficient sensorimotor gating nor ketamine-induced ...
Cyclin D1 [SP4] Antibody (cGMP). - enQuire BioReagents
anti-Sp3 Antibody | Technique alternative | 01012193048 - Biovisi
Sp-3, Sp3, SP 3, SP-3, SP3 transcription factor, transcription factor SP 3, Transcription factor SP3 ... The Sp family is comprised of Sp1, Sp2, Sp3 and Sp4 that regulates transcription by binding to consensus GC- and GT-box ... Sp3 has been shown to have to a bifunctional transcription factor that can either stimulates or represses the transcription of ... Sp transcription factor family has a highly conserved DNA-binding domain composed of zinc fingers. ...
Objective Increased activity of Sp family of transcription factors is a - New dimension in therapeutic targeting of BCL-2 family
Sp transcription elements like Sp1 Sp3 and Sp4 have an effect on multiple cellular procedures and also have been involved with ... Objective Increased activity of Sp family of transcription factors is a. * Post author By colinsbraincancer ... Objective Increased activity of Sp family of transcription factors is a frequent and essential event in cancer development and ... The kinesin spindle protein (KSP) a microtubule electric motor protein is → History The epidermal growth factor receptor (EGFR ...
Emerging role of long noncoding RNA-encoded micropeptides in cancer | Cancer Cell International | Full Text
SRSP promoted SRSF3 binding to transcription factor Sp4 exon 3, contributed to promoting the formation of the "oncogene" long ... IMP was shown to be highly homologous to transcription factors related to inflammatory immune response factors, such as nuclear ... short Sp4 isoform. Overall, their findings revealed that the lncRNA-encoded micropeptide SRSP promoted "oncogene" Sp4 splicing ... Insulin-like growth factor 2 mRNA-binding protein 1. CASIMO1 :. Cancer-associated small integral membrane open reading frame 1 ...
Microarray characterization of gene expression changes in blood during acute ethanol exposure | BMC Medical Genomics | Full Text
Analysis showed function-based networks, shared transcription factor binding sites and signaling pathways for members of the ... pathway membership and common transcription factor binding within and across clusters. RT-qPCR was used with representative ... a factor induced by IL-4 in B lymphocytes [79], SP4 a transcription factor that regulates NF-κB [80], two ubiquitination ... In yellow are non-p38 MAPK pathway transcription factors and their target GOIs. In orange are transcription factors and GOIs ...
Several agents utilized for treatment of colon and additional cancers induce - TAM Receptor Signaling in Immune Homeostasis
Sp Transcription Factors Members of the Sp/KLF family have a highly conserved DNA binding website that consists of three ... Factors Research with this laboratory has focused on developing anticancer medicines that downregulate Sp1 Sp3 and Sp4 protein ... Part of ROS in Drug Mediated KT3 tag antibody Dowregulation of Sp Transcription Factors Studies with this laboratory have shown ... To this effect our laboratory has focused on specificity protein (Sp) transcription factors (TFs) since Sp1 and additional Sp ...
Cancer cells show altered metabolism seen as a the era of - Proteases & Other Enzymes Pathways
Genes known to be regulated by Sp transcription factors are shown in bold; proteins known to be aberrant in tumor cells are ... Sp1 through Sp4 type a subgroup which has glutamine-rich transactivating domains (TADs). Sp1 Sp3 and Sp4 possess 2 TADs whereas ... transcription factors (at least 20 in mammals).5 6 These proteins share a conserved DNA binding domain highly. Through 3 ... Proof is shown for the idea that Sp transcription elements may act in collaboration with Akt to modify the abnormal rate of ...
Double heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis | International Journal of...
KIF3C as an important genetic combination in HGF manifestation and suggest that ZNF513 mutation may be a major risk factor for ... ZNF513, a transcription factor, binds to KIF3C exon 1 and participates in the positive regulation of KIF3C expression in ... ZNF513, a transcription factor, binds to KIF3C exon 1 and participates in the positive regulation of KIF3C expression in ... used ChIP analysis to reveal that ZNF513 binds to the Arr3, Sp4, Pax6, Irbp, and photoreceptor opsin promoters.21 In our study ...
Phosphorylation of transcription factor specificity protein 4 is increased in peripheral blood mononuclear cells of first...
Also, SP4 levels are modulated by lithium treatment in cultured neurons. Phosphorylation of SP4 at S770 is increased in the ... Reduced levels of SP4 protein have recently been reported in peripheral blood mononuclear cells in first-episode psychosis. ... This pilot study suggests that S770 SP4 phosphorylation could be a peripheral biomarker of psychosis, and may be regulated by ... The aim of this study was to investigate whether SP4 S770 phosphorylation is increased in lymphocytes of first-episode ...
Dussor, Gregory
In women, we find the differentially expressed transcription factor SP4 that is known to drive a regulatory program, and may ... We show that pronociceptive and inflammatory factors, such as nerve growth factor (NGF), interleukin-6 (IL-6), and carrageenan ... Our findings demonstrate that the MNK1/2-eIF4E signaling axis is an important contributing factor to mechanisms of nociceptor ... These pathways convergently signal to the eukaryotic translation initiation factor (eIF) 4F complex to regulate the ...
New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma | Acta Neuropathologica Communications |...
TERTp duplications (TERTpdup) mainly affected the binding capacity of two transcription factors families, i.e. the members of ... In fact, these new TERTpdup significantly enhanced the E-twenty-six transcription factors binding capacity, which is also ... 5 fold increase of TERT transcription. The present study provides new insights into TERTp mutational spectrum occurring in ... the E-twenty-six and the Specificity Protein/Krüppel-Like Factor groups. ...
The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction |...
The authors presented a comprehensive analysis of the effects of RBM12 on cAMP signaling and cAMP-induced transcription. All ... Do mutations in any of these other rare risk genes converge on GPCR? (transcriptional regulation (SP4, RB1CC1), splicing (SRRM2 ... The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction *Khairunnisa M. Semesta ... Factors involved in synaptic plasticity and schizophrenia such as JUN, ARC (encoding the activity-regulated cytoskeleton- ...
Comments: Identifizierung potentieller Zielgene des Transkriptionsfaktors Sp3 in vitro und in vivo :: Publikationsserver
Transcription factor Sp2: Molecular characterization and generation of Sp2 gene targeted mice by: Baur, Frank Published: (2005 ... Der ubiquitär vorkommende Transkriptionsfaktor Sp3 (Specificity protein) sowie Sp1, Sp2 und Sp4 gehören zu einer Protein- ... Transcription factor Sp3 as target for SUMOylation in vivo by: Rischitor, Grigore Published: (2005) ...