Cotransporter - Wikipedia
Na+/phosphate cotransporter (NaPi) - Sodium-phosphate cotransporters are from the SLC34 and SLC20 protein families. They are ... NaPi that couples with 2 Na+ and 1 divalent Pi are classified as NaPi IIc. Na+/I− symporter (NIS) - Sodium-Iodide is a type of ... Na-K-2Cl symporter K-Cl cotransporter Sodium/phosphate cotransporter Sodium-glucose transport proteins Glucose transporter ... Na+/glucose cotransporter (SGLT1) - is also known as sodium-glucose cotransporter 1 and is encoded by the SLC5A1 gene. SGLT1 is ...
Role of pyrophosphate in vascular calcification in chronic kidney disease | Nefrología
Subsequent studies have shown43 that PFA is not an effective inhibitor of sodium-phosphate co-transporter type III (Pit1 and ... Compensatory regulation of the sodium/phosphate cotransporters NaPi-IIc (SCL34A3) and Pit-2 (SLC20A2) during Pi deprivation and ... The SLC20 family of proteins: dual functions as sodium-phosphate cotransporters and viral receptors. ... Phosphate transport. The main phosphate transporter family is the sodium-dependent phosphate cotransporter, also known as NaPi ...
Genetics of kidney stone disease | Nature Reviews Urology
... a G protein-coupled receptor) signalling pathway; and the metabolic pathways for vitamin D, oxalate, cysteine, purines and uric ... the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate ... rickets with hypercalciuria predict a key role for the sodium-phosphate cotransporter NaPi-IIc in maintaining phosphate ... Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. J. Biol. Chem. 276, 9206-9213 (2001). ...
TCDB » SEARCH
2002). The nptA gene of Vibrio cholerae encodes a functional sodium-dependent phosphate cotransporter homologous to the type II ... 2001). Interaction of the type IIa Na/P. i cotransporter with PDZ proteins. J. Biol. Chem. 276: 9206-9213. 11099500 ... 2009). Substrate interactions of the electroneutral Na+-coupled inorganic phosphate cotransporter (NaPi-IIc). J Physiol. 587(Pt ... 2016). Characterizing and evaluating the expression of the type IIb sodium-dependent phosphate cotransporter (slc34a2) gene and ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
Hyperphosphatemia: Practice Essentials, Background, Pathophysiology
... decreased phosphate excretion, or a disorder that shifts intracellular phosphate to extracellular space. (See Pathophysiology, ... an abnormally high serum phosphate level, can result from increased phosphate (PO4) intake, ... Phosphate absorption in the remainder of the nephron is generally mediated by type 3 sodium phosphate cotransporters. No direct ... Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol. 2009 Jan. 20(1):104-13. [QxMD ...
Hypophosphatemia: Practice Essentials, Background, Pathophysiology
Hypophosphatemia is defined as a phosphate level of less than 2.5 mg/dL (0. ... were initially identified as viral transport proteins. Almost all cells express type 3 sodium phosphate cotransporters; ... Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol. 2009. 20:104-113. [QxMD MEDLINE ... 12] In the proximal tubule, phosphate reabsorption by type 2 sodium phosphate cotransporters is regulated by dietary phosphate ...
Pathophysiological Implication of Vitamin D in Diabetic Kidney Disease | Kidney and Blood Pressure Research | Karger Publishers
Excess of sodium boosts phosphate reabsorption via SLC34A1 (NaPi-IIa) and SLC34A3 (NaPi-IIc) co-transporters, and increased ... PTC, proximal tubule cell; VDBP, vitamin D binding protein; SGLT2, sodium-glucose co-transporter 2; NaPi-IIa/c, sodium- ... Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: cardiovascular and renal benefits in patients with chronic ... sodium-glucose co-transporter 2; NaPi-IIa/c, sodium-phosphate co-transporter IIa/c; GLUT2, glucose transporter 2. ...
Bone Mineralization and Related Disorders: Practice Essentials, Vitamin D Metabolism, Pathophysiology
... which encodes the renal type IIc sodium-phosphate cotransporter (NaPi-IIc). The typical presentation is severe rickets, ... a phosphate-regulating gene with homologies to endopeptidases on the X chromosome) and dentin matrix protein 1 (DMP1), ... Hypophosphatemic rickets with hypercalciuria due to mutation in SLC34A3/type IIc sodium-phosphate cotransporter: presentation ... Dysfunctions in tubular phosphate reabsorption via the sodium-phosphate cotransporter, endocytotic reabsorption of the vitamin ...
Frontiers | Endocrine Diseases of Newborn: Epidemiology, Pathogenesis, Therapeutic Options, and Outcome "Current Insights Into...
The bone minerals calcium, phosphate and magnesium are all maintained at higher concentrations in utero to achieve adequate ... This article will guide clinicians through an updated review of calcium and phosphate physiology, then review specific ... This article will guide clinicians through an updated review of calcium and phosphate physiology, then review specific ... and hormone regulation factors have changed the understanding of calcium and phosphate homeostasis in the fetus and the newborn ...
Pesquisa | Portal Regional da BVS
Mutations in the SLC34A3 gene, a sodium-dependent inorganic phosphate (Pi) cotransporter, also referred to as NaPi IIc, causes ... and liver-type fatty acid-binding protein, and compared the values with the change in the estimated glomerular filtration rate ... Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2bâ º/â » mice. ... Sodium-dependent phosphate cotransporters: lessons from gene knockout and mutation studies. Miyamoto, Ken-ichi; Haito-Sugino, ...
"sequence id","alias","species","description",...
","Putative sodium:phosphate symporter [Ensembl]. PhoU domain, Na+/Pi-cotransporter [Interproscan].","protein_coding" "CCL20148 ... "type IV secretion system protein VirB11 [Ensembl]. Type II/IV secretion system protein [Interproscan].","protein_coding" " ... "protein_coding" "AAC75228","fruA","Escherichia coli","fused fructose-specific PTS enzymes: IIBcomponent/IIC components [Ensembl ... "protein_coding" "CCL20576","rpsZ","Clostridioides difficile","30S ribosomal protein S14 type Z [Ensembl]. Ribosomal protein ...
Overlapping Phenotypes Associated With CYP24A1, SLC34A1, and SLC34A3 Mutations: A Cohort Study of Patients With...
... cause autosomal recessive Infantile Hypercalcemia type 1 and 2, illustrating links between vitamin D and phosphate metabolism. ... Sodium-Phosphate Cotransporter Proteins, Type IIc / genetics* Actions. * Search in PubMed * Search in MeSH ... cause autosomal recessive Infantile Hypercalcemia type 1 and 2, illustrating links between vitamin D and phosphate metabolism. ... Serum calcium dot lines: normal values 2.2-2.7 mmol/L. Serum phosphate dot lines: -2-+2SD. Serum PTH dot line: 15 pg/mL. 25-OH- ...
MeSH Browser
Sodium-Phosphate Symporter Proteins, Type IIc Type IIc Sodium-Phosphate Cotransporter Proteins Type IIc Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.530.937.704] * Sodium-Phosphate Cotransporter Proteins, Type IIa ... Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.648.500.750.750] * Sodium-Phosphate Cotransporter Proteins, Type ... Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.543.585.937.829] * Sodium-Phosphate Cotransporter Proteins, Type IIa ...
MeSH Browser
Sodium-Phosphate Symporter Proteins, Type IIc Type IIc Sodium-Phosphate Cotransporter Proteins Type IIc Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.530.937.704] * Sodium-Phosphate Cotransporter Proteins, Type IIa ... Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.157.648.500.750.750] * Sodium-Phosphate Cotransporter Proteins, Type ... Sodium-Phosphate Cotransporter Proteins, Type II [D12.776.543.585.937.829] * Sodium-Phosphate Cotransporter Proteins, Type IIa ...
DeCS
Type IIc Sodium Phosphate Cotransporter Proteins Type IIc Sodium Phosphate Symporter Proteins Type IIc Sodium-Phosphate ... Type IIc Sodium Phosphate Cotransporter Proteins. Type IIc Sodium Phosphate Symporter Proteins. Type IIc Sodium-Phosphate ... Sodium Phosphate Cotransporter Proteins, Type IIc Sodium Phosphate Symporter Proteins, Type IIc Sodium-Phosphate Symporter ... Sodium Phosphate Cotransporter Proteins, Type IIc. Sodium Phosphate Symporter Proteins, Type IIc. Sodium-Phosphate Symporter ...
NDF-RT Code NDF-RT Name
Type IIb N0000169717 Sodium-Phosphate Cotransporter Proteins, Type IIc N0000169714 Sodium-Phosphate Cotransporter Proteins, ... Type I N0000169716 Sodium-Phosphate Cotransporter Proteins, Type II N0000169719 Sodium-Phosphate Cotransporter Proteins, Type ... Hormone N0000169713 Sodium-Phosphate Cotransporter Proteins N0000169715 Sodium-Phosphate Cotransporter Proteins, ... Type I N0000169422 Antifreeze Proteins, Type II N0000169423 Antifreeze Proteins, Type III N0000169421 Antifreeze Proteins, Type ...
Sodium-Phosphate Cotransporter Proteins (definition)
Sodium-Phosphate Cotransporter Proteins, Type IIc. Other names Type II Sodium Phosphate Symporter Proteins; Type II Sodium ... Type II Na Dependent Phosphate Cotransporter; Sodium Phosphate Cotransporter Proteins, Type II; Type II Sodium-. Phosphate ... Symporter Proteins; Type II Na-. Dependent Phosphate Cotransporter; Type II Sodium-. Phosphate Cotransporter Proteins To share ... Examples Sodium-Phosphate Cotransporter Proteins, Type IIa. ; Sodium-Phosphate Cotransporter Proteins, Type IIb ...
Hyperphosphatemia Treatment & Management: Approach Considerations, Phosphate Binders, Increased Renal Excretion
... decreased phosphate excretion, or a disorder that shifts intracellular phosphate to extracellular space. (See Pathophysiology, ... an abnormally high serum phosphate level, can result from increased phosphate (PO4) intake, ... Phosphate absorption in the remainder of the nephron is generally mediated by type 3 sodium phosphate cotransporters. No direct ... Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol. 2009 Jan. 20(1):104-13. [QxMD ...
Hyperphosphatemia Treatment & Management: Approach Considerations, Phosphate Binders, Increased Renal Excretion
... decreased phosphate excretion, or a disorder that shifts intracellular phosphate to extracellular space. (See Pathophysiology, ... an abnormally high serum phosphate level, can result from increased phosphate (PO4) intake, ... Phosphate absorption in the remainder of the nephron is generally mediated by type 3 sodium phosphate cotransporters. No direct ... Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol. 2009 Jan. 20(1):104-13. [QxMD ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
Biomarkers Search
5. Segment-specific expression of sodium-phosphate cotransporters NaPi-IIa and -IIc and interacting proteins in mouse renal ... 2. Vitamin D and type II sodium-dependent phosphate cotransporters.. Kido S; Kaneko I; Tatsumi S; Segawa H; Miyamoto K. Contrib ... Type II Na+-Pi cotransporters in osteoblast mineral formation: regulation by inorganic phosphate.. Lundquist P; Murer H; Biber ... Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1 ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
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Sodium-Phosphate Cotransporter Proteins, Type IIc D12.776.157.530.937.704.500 D12.776.543.585.937.829.500 Sodium-Phosphate ... Sodium-Phosphate Cotransporter Proteins, Type II D12.776.157.530.937.704 D12.776.543.585.937.829 Sodium-Phosphate Cotransporter ... Proteins, Type IIa D12.776.157.530.937.704.124 D12.776.543.585.937.829.124 Sodium-Phosphate Cotransporter Proteins, Type IIb ... Cotransporter Proteins, Type III D12.776.157.530.937.719 D12.776.543.585.937.844 Sodium-Potassium-Chloride Symporters D12.776. ...
Hyperphosphatemia: Practice Essentials, Background, Pathophysiology
... decreased phosphate excretion, or a disorder that shifts intracellular phosphate to extracellular space. (See Pathophysiology, ... an abnormally high serum phosphate level, can result from increased phosphate (PO4) intake, ... In the proximal tubule, phosphate reabsorption by type 2 sodium phosphate cotransporters is regulated by dietary phosphate, PTH ... Type 3 transporters were initially identified as viral transport proteins. Almost all cells express type 3 sodium phosphate ...
Bone Mineralization and Related Disorders: Practice Essentials, Vitamin D Metabolism, Pathophysiology
... which encodes the renal type IIc sodium-phosphate cotransporter (NaPi-IIc). The typical presentation is severe rickets, ... a phosphate-regulating gene with homologies to endopeptidases on the X chromosome) and dentin matrix protein 1 (DMP1), ... Hypophosphatemic rickets with hypercalciuria due to mutation in SLC34A3/type IIc sodium-phosphate cotransporter: presentation ... Dysfunctions in tubular phosphate reabsorption via the sodium-phosphate cotransporter, endocytotic reabsorption of the vitamin ...
Pesquisa | Portal Regional da BVS
Differential modulation of the molecular dynamics of the type IIa and IIc sodium phosphate cotransporters by parathyroid ... There was increased nuclear expression of the endogenous LXR receptor, a reduction in NaPi4 protein abundance (the main type II ... The kidney is a key regulator of phosphate homeostasis. There are two predominant renal sodium phosphate cotransporters, NaPi2a ... demonstrated that ATF4 transcriptionally upregulates the expression of type III sodium-dependent phosphate cotransporters (PiT1 ...
X-Linked Hypophosphatemia - GeneReviews® - NCBI Bookshelf
... causes hypophosphatemia through internalization of the sodium-phosphate IIa and IIc cotransporters from the renal proximal ... Protein. Locus-Specific Databases. HGMD. ClinVar. PHEX Xp22. .11 Phosphate-regulating neutral endopeptidase PHEX PHEX database ... tubular reabsorption of phosphate and 1,25(OH)2D serum levels are associated with PHEX mutation type. BMC Med Genet. 2011;12: ... While PHEX is expressed primarily in cells of bone and teeth lineage, the main protein effects on renal phosphate wasting and ...
May | 2023 | Beta Amyloid Signal
Wild-type NaPi-IIc, your cotransporter NaPi-IIa, in addition to a number of IIa-IIc chimeras as well as erradication mutants, ... The kind IIc Na+-dependent phosphate cotransporter (NaPi-IIc) is especially focused to, along with depicted in, your apical ... Luminescent EGFP-fused NaPi-IIc transporter healthy proteins are generally correctly indicated inside the apical tissue layer ... the root base after Twenty four they would increased by greater than a element of 2 in the versions with NaNO2 and sodium ...
Browse In Canada | EDM Case Reports
... recessive disorder caused by mutations in the SLC34A3 gene that encodes the renal sodium-dependent phosphate cotransporter 2c ( ... Management includes avoiding fasting and restricting dietary protein and fat. Conversely, type 2 diabetes mellitus (T2DM) ... NaPi-IIc). It may present as intermittent mild hypercalcemia which may attract initial diagnostic attention but appreciation of ... She was started on oral phosphate replacement which normalized her serum phosphate, serum calcium and urine calcium levels over ...