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*  The Clinical Study of Sex Chromosome Variants - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. Ovarian ... or diagnostic labs as having sex-chromosome variants causing deletion/duplication of sex-linked genes or entire sex chromosomes ... The Clinical Study of Sex Chromosome Variants. The safety and scientific validity of this study is the responsibility of the ...
  https://www.clinicaltrials.gov/ct2/show/NCT01661010?term=xxy&cond=klinefelter%27s+syndrome&cntry=US&rank=8
*  Growth Hormone Treatment of Women With Turner Syndrome - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. Ovarian ...
  https://clinicaltrials.gov/ct2/show/NCT00420654?cond=%22Turner+syndrome%22&rank=7
*  Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome - Full Text View -...
Sex Chromosome Disorders of Sex Development. Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders. ... Chromosome Disorders. Congenital Abnormalities. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. ... Change from baseline on the Bruininks-Oseretsky Test of Motor Development - 2 [ Time Frame: Visit 1 (baseline) and Visit 5 (1 ... 47,XXY plus another genetic disorder. *Non-English speaking individuals (because the psychological tests are administered in ...
  https://clinicaltrials.gov/ct2/show/NCT01585831?recr=Open&cond=%22Klinefelter+Syndrome%22&rank=1
*  Epigenetics and Metabolic Disorders in Men With the Klinefelter Syndrome - Full Text View - ClinicalTrials.gov
Sex Chromosome Disorders of Sex Development. Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders. ... The Klinefelter Syndrome is one of the most common genetic disorders in men. The patients have one supernumerary X-chromosome, ... Epigenetics and Metabolic Disorders in Men With the Klinefelter Syndrome (IZKF-CRA03-09). The safety and scientific validity of ... Switching on and off of specific genes on the X-chromosome is differential, depending on the origin either from the maternal or ...
  https://clinicaltrials.gov/ct2/show/NCT01703676
*  Androgen for Leydig Cell Proliferation - Full Text View - ClinicalTrials.gov
Sex Chromosome Disorders of Sex Development. Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders. ... Chromosome Disorders. Congenital Abnormalities. Genetic Diseases, Inborn. Testosterone. Testosterone enanthate. Testosterone ... Gonadal Disorders. Endocrine System Diseases. Infertility, Male. Infertility. Genital Diseases, Male. ...
  https://clinicaltrials.gov/ct2/show/NCT01206270?term=klinefelter
*  National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions - Full Text View -...
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Recurrent chromosome 16p13.1 duplications are a risk factor for aortic dissections. PLoS Genet. 2011 Jun;7(6):e1002118. doi: ... Autosomal and X chromosome structural variants are associated with congenital heart defects in Turner syndrome: The NHLBI ...
  https://clinicaltrials.gov/ct2/show/NCT01322165?cond=%22craniosynostoses%22+OR+%22muenke+syndrome%22&rank=13
*  Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Congenital Abnormalities. Sex Chromosome Disorders of Sex Development. ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Dehydroepiandrosterone. Adjuvants, Immunologic. ...
  https://clinicaltrials.gov/ct2/show/NCT00650754
*  The Effects of Estrogen on Cognition in Girls With Turner Syndrome - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. Ovarian ... The development of the brain in females is a result of a combination of factors. During puberty estrogen plays a role in ... Estrogen influences brain development in females at puberty. Environmental and cultural factors interact with the biological ...
  https://www.clinicaltrials.gov/ct2/show/NCT00001253
*  Observational Study of Somatropin Treatment in Children - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Ovarian Diseases. Adnexal Diseases ... Development of additional pituitary hormone deficiencies in pediatric patients originally diagnosed with idiopathic isolated GH ... Untreated patients with presence or history of neoplastic disease evaluated for endocrine or growth disorder or with any SHOX ...
  https://clinicaltrials.gov/ct2/show/NCT01088412?cond=%22metatropic+dysplasia%22+OR+%22Dwarfism%22&rank=9
*  Evaluation of the Adherence and the Patient Acceptability of Zomacton┬« Treatment With the Zomajet┬« Vision X Device - Full Text...
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Ovarian Diseases. Adnexal Diseases ...
  https://clinicaltrials.gov/ct2/show/NCT02018172?recr=Open&cond=%22Turner+Syndrome%22&rank=13
*  Risk of Diabetes in Young Turner Syndrome Patients - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. Ovarian ... Turner Syndrome is a common genetic disorder. Seventy percent of adults with Turner Syndrome have abnormalities in glucose ...
  https://clinicaltrials.gov/ct2/show/NCT02160717?term=NCT02160717&rank=1
*  Klinefelter Fertility Preservation - Full Text View - ClinicalTrials.gov
Sex Chromosome Disorders of Sex Development. Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders. ... Chromosome Disorders. Congenital Abnormalities. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. ...
  https://clinicaltrials.gov/ct2/show/NCT01817296?cond=%22klinefelter+syndrome%22&rank=7
*  X-chromosome Inactivation, Epigenetics and the Transcriptome - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. Ovarian ... The human genetic material consists of 46 chromosomes of which two are sex chromosomes. The sex-chromosome from the mother is ... Alterations in the number of sex-chromosomes and in particular the X-chromosome is fundamental to the development of numerous ...
  https://clinicaltrials.gov/ct2/show/NCT01678261?recr=Open&cond=%22Klinefelter+Syndrome%22&rank=4
*  Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome - Full Text View - ClinicalTrials.gov
Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders of Sex Development. Heart Defects, Congenital ... Sex Chromosome Disorders. Chromosome Disorders. Genetic Diseases, Inborn. Gonadal Disorders. Endocrine System Diseases. Ovarian ... Sex chromosome. Turner Syndrome. Marfan syndrome. Bicuspid aortic valve. Aortic Aneurysm. Epigenetics. Transcriptome. non- ... Turner syndrome is a congenital complete or partial lack of one of the female sex chromosomes affecting 1 of 2000 live born ...
  https://clinicaltrials.gov/ct2/show/NCT01760668?recr=Open&cond=%22Marfan+Syndrome%22&rank=1
*  Non-Invasive Determination of Fetal Chromosome Abnormalities - Full Text View - ClinicalTrials.gov
Sex Chromosome Disorders of Sex Development. Disorders of Sex Development. Urogenital Abnormalities. Sex Chromosome Disorders. ... Chromosome Aberrations. Chromosome Disorders. Disease. Pathologic Processes. Intellectual Disability. Neurobehavioral ... Non-Invasive Determination of Fetal Chromosome Abnormalities. The safety and scientific validity of this study is the ... to use a new marker in the maternal blood to better identify pregnancies that have a child with a chromosome abnormality such ...
  https://clinicaltrials.gov/ct2/show/NCT00891852?cond=%22klinefelter+syndrome%22&rank=12
*  Melvin M. Grumbach - Wikipedia
... the function of the human sex chromosomes; and disorders of sexual development. After graduating from New Utrecht High School ... sex determination and differentiation (and their disorders) and disease-causing pathology. He was a past president of the ... for his research and writing on the effect of hormones and the central nervous system on growth and puberty and their disorders ... made many seminal contributions the understanding of pediatric endocrinology including extensive studies on the development and ...
  https://en.wikipedia.org/wiki/Melvin_M._Grumbach
*  Gender reveal - Wikipedia
The tests are not perfectly accurate, and in cases of sex chromosome disorders or other abnormalities of development their ... Some[weasel words] argue that the term "gender reveal" is a misnomer, as all available tests measure the child's sex, which is ... Previously, the sex of the unborn baby was determined via obstetric ultrasonography between 16-20 weeks. ... However, it is typically held earlier, near the moment, formerly private, when parents learn the baby's predicted sex. Gender ...
  https://en.wikipedia.org/wiki/Gender_reveal
*  The Focus Foundation - Wikipedia
Sex Chromosome Disorders: A Very Common but Rarely Diagnosed Disorder appeared as a Special Feature May/June 2011 in the online ... Samango-Sprouse supported the efforts in content development and delivery as well as participating in recruitment, training ... NFC gfcvbhf The Foundation attempts to increase awareness about sex chromosome disorders in order to help children with these ... practitioners often receive insufficient information about sex chromosome disorders, and don't often test for X & Y Variations ...
  https://en.wikipedia.org/wiki/The_Focus_Foundation
*  Creatine transporter defect - Wikipedia
... semantic-pragmatic language disorder, oral dyspraxia, extrapyramidal movement disorder, constipation, absent speech development ... The SLC6A8 gene is located on the short arm of the sex chromosome, Xq28. Hemizygous males with CTD express speech and behavior ... Furthermore, a family history of X-linked intellectual disability, developmental coordination disorder, and seizures is ... CTD is an X-linked disorder caused by mutations in the SLC6A8 gene. ...
  https://en.wikipedia.org/wiki/Creatine_transporter_defect
*  History of intersex surgery - Wikipedia
"Disorders of sex development" (DSD). More specifically, these terms refer to "congenital conditions in which development of ... with female chromosomes, and ovaries and uterus inside, and we recommend that you change your sex to match your chromosomes and ... "Surgery in disorders of sex development (DSD) with a gender issue: If (why), when, and how?". Journal of Pediatric Urology. 12 ... A 2016 paper on "Surgery in disorders of sex development (DSD) with a gender issue" repeated many of the same claims, but ...
  https://en.wikipedia.org/wiki/History_of_intersex_surgery
*  Polysomy - Wikipedia
Some of the most frequent genetic disorders are abnormalities of sex chromosomes, but polysomies rarely occur. 49,XXXXY ... During egg or sperm development the 21st chromosome does not separate during either the egg or sperm development. The end ... X chromosome. Polysomy of sex chromosomes is caused by successive nondisjunctions in meiosis I and II. In squamous cell ... Chromosome 1 may contain a gene responsible for tumor development and lead to changes in the karyotype, including fusion of the ...
  https://en.wikipedia.org/wiki/Polysomy
*  Turner syndrome - Wikipedia
Especially in mosaic cases of Turner syndrome that contains Y-chromosome (e.g. 45,X/46,XY) due to the risk of development of ... Ford CE, Jones KW, Polani PE, De Almeida JC, Briggs JH (1959). "A sex-chromosome anomaly in a case of gonadal dysgenesis ( ... Approximately one-third of all women with Turner syndrome have a thyroid disorder. Usually it is hypothyroidism, specifically ... Other human sex chromosome aneuploids: XYY syndrome, Klinefelter syndrome (XXY), Triple X syndrome, Dermatoglyphics, Noonan ...
  https://en.wikipedia.org/wiki/Turner_syndrome
*  Testis-determining factor - Wikipedia
XX Testicular Disorder of Sex Development OMIM entries on 46,XX Testicular Disorder of Sex Development Genes, sry at the US ... Monotremes lack SRY and some of their sex chromosomes share homology with bird sex chromosomes. SRY is a quickly evolving gene ... "Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes". Genome Res. 18 (6): 965-73. doi:10.1101/ ... "Analysis of the sex-determining region of the Y chromosome (SRY) in sex reversed patients: point-mutation in SRY causing sex- ...
  https://en.wikipedia.org/wiki/Testis-determining_factor
*  Patricia Jacobs - Wikipedia
"Prenatal diagnosis of sex chromosome abnormalities". In Milunsky, Aubrey; Milunsky, Jeff M. Genetic disorders and the fetus: ... Pubertal development is normal and these men are usually fertile. "Professor Patricia Jacobs , Medicine , University of ... Harper, Peter S. (2006). "The sex chromosomes". First years of human chromosomes : the beginnings of human cytogenetics. ... ISBN 1-4051-9087-6. The addition of a Y chromosome to a normal male chromosome constitution does not produce a discernible ...
  https://en.wikipedia.org/wiki/Patricia_Jacobs