We identify the SUMO ligase Protein Inhibitor of Activated STAT1 (PIAS1) as a constituent PML-NB protein. We show that PIAS1 ... The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic ... The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic ... constituent proteins. During herpesvirus infection, these antiviral proteins are independently recruited to nuclear domains ...

Among these, histone H1, histone H3, and p160 Myb-binding protein 1A were further characterized as novel SUMO-1 substrates. The ... Among these, histone H1, histone H3, and p160 Myb-binding protein 1A were further characterized as novel SUMO-1 substrates. The ... ribosomal proteins, histones, RNA-binding proteins, and transcription factor regulators. ... ribosomal proteins, histones, RNA-binding proteins, and transcription factor regulators. ...

Plasmid pSUMO His6 SUMO AMPKa (11-281) from Dr. Karsten Melchers lab contains the insert AMPK a1 and is published in Cell Res ... 2015 Jan;25(1):50-66. doi: 10.1038/cr.2014.150. Epub 2014 Nov 21. This plasmid is available through Addgene. ... Tag / Fusion Protein *6xHis-SUMO (N terminal on insert). Cloning Information * Cloning method Restriction Enzyme ... 2015 Jan;25(1):50-66. doi: 10.1038/cr.2014.150. Epub 2014 Nov 21. 10.1038/cr.2014.150 PubMed 25412657 ...

SUMO-2 and SUMO-3 are conjugated to a wide, but poorly defined range of target proteins and play important roles in many ... While SUMO-2 and SUMO-3 are 98 % identical, they are only 50 % identical to SUMO-1. Preliminary data indicate that SUMO-2 and ... SUMO is attached only to a specific lysine residue in the target protein. In higher eukaryotes, the SUMOylation targets ... and protein modification by SUMO does not have a common functional consequence.. Employment of most modern proteomic and ...

... centrosomal protein 76), and APP (Amyloid-beta precursor protein). There are no paralogs for KIAA1143 KIAA1143 has homologs in ... "GPS SUMO for KIAA1143". Retrieved 16 December 2022. "YinOYang Analysis". Retrieved 16 December 2022. "Myhits Motif scan". ... The KIAA1143 protein belongs to the uncharacterized protein KIAA1143-like Family, and contains DUF4604 domain of unknown ... KIAA1143 is an uncharacterized protein in humans that is encoded by the KIAA1143 gene. it may play a role in cell growth ...

Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as ... Recombinant Mouse DEFB1/ Beta-defensin 1 Protein, His-SUMO, E.coli-50ug. ...

Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic ... 3D Structures in the Protein Data Bank *Computed Structure ... Here we report crystal structures for human SUMO E1 in complex with SUMO adenylate and tetrahedral intermediate analogues at ... SUMO-activating enzyme subunit 2. B. 551. Homo sapiens. Mutation(s): 1 Gene Names: HRIHFB2115, SAE2, UBA2, UBLE1B. EC: 6.3.2 ( ... Active site remodelling accompanies thioester bond formation in the SUMO E1.. Olsen, S.K., Capili, A.D., Lu, X., Tan, D.S., ...

His-SUMO-tagged from Creative Biomart. Recombinant Human WDR77 Protein, His-SUMO-tagged can be used for research. ... Recombinant Human WDR77 Protein, His-SUMO-tagged. Cat.No. : WDR77-1049H. Product Overview :. Recombinant Human WDR77 Protein (1 ... Recombinant Human WDR77 Protein, GST-tagged. +Inquiry. WDR77-6232R. Recombinant Rat WDR77 Protein, His (Fc)-Avi-tagged. + ... Recombinant Mouse WDR77 Protein, His (Fc)-Avi-tagged. +Inquiry. WDR77-5018R. Recombinant Rhesus Macaque WDR77 Protein, His (Fc ...

Non-covalent Interaction With SUMO Enhances the Activity of Human Cytomegalovirus Protein IE1. Title. Non-covalent Interaction ... It is a multifunctional and conditionally essential protein for HCMV infection. SUMO signaling regulates several cellular ... Consequently, IE1 exploits SUMO signaling to regulate these pathways. The covalent interaction of IE1 and SUMO (IE1-SUMOylation ... Non-covalent Interaction With SUMO Enhances the Activity of Human Cytomegalovirus Protein IE1. ...

Enables SUMO activating enzyme activity. Predicted to be involved in positive regulation of protein sumoylation and protein ... General protein information Go to the top of the page Help Preferred Names. SUMO-activating enzyme subunit 2. Names. SUMO1 ... Protein Expr Purif, 2003 Jul. PMID 12821332 * SUMO conjugation and deconjugation. Schwienhorst I, et al. Mol Gen Genet, 2000 ... mRNA and Protein(s) * XM_017322348.3 → XP_017177837.1 SUMO-activating enzyme subunit 2 isoform X1 ...

... is an Escherichia coli Protein fragment 366 to 802 aa range, , 90% purity and validated in SDS-PAGE. ... Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Cell lines and Lysates. Multiplex ... Epigenetics and Nuclear Signaling Chromatin Binding Proteins Methylated DNA Share by email ...

An emerging theme is that TonEBP is a stress protein that mediates the cellular response to a range of pathological insults, ... Numerous studies since then have revealed that TonEBP is a pleiotropic stress protein that is involved in a range of ... TonEBP is a DNA-binding protein with multiple roles, via transcription regulation and other mechanisms, in both protective and ... Tonicity-responsive enhancer-binding protein (TonEBP), which is also known as nuclear factor of activated T cells 5 (NFAT5), ...

PDB Description: solution structure of human sumo-2 (smt3b), a ubiquitin-like protein ... PDB Compounds: (A:) Ubiquitin-like protein SMT3B. SCOPe Domain Sequences for d1wz0a1:. Sequence; same for both SEQRES and ATOM ... Class d: Alpha and beta proteins (a+b) [53931] (396 folds). *. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (15 superfamilies ... SCOPe: Structural Classification of Proteins - extended. Release 2.08 (updated 2023-01-06, stable release September 2021) ...

H1 Cell division protein FtsZ (ftsZ) from Cusabio. Cat Number: CSB-EP359270EGX. USA, UK & Europe Distribution. ... N-terminal 10xHis-SUMO-tagged Recombinant * N-terminal 10XHis-tag & C-terminal Myc-tag Rec ... Recombinant Escherichia coli O6:H1 Cell division protein FtsZ (ftsZ) , CSB-EP359270EGX. (No reviews yet) Write a Review Write a ... Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of ...

In this study, we found that RING finger protein 4 (RNF4), a RING finger E3 ubiquitin ligase, is required for the RIPK1 ... Receptor-interacting protein kinase 1 (RIPK1) is a key component of the tumor necrosis factor (TNF) receptor signaling complex ... through downregulation of transforming growth factor β-activated kinase 1 (TAK1) activity, indicating the possibility that RNF4 ... SUMO)-targeted ubiquitin ligase (STUbL) [12,13]. RNF4 recognizes and ubiquitinates polysumoylated proteins via its SUMO- ...

Recombinant Human SENP3 Protein expressed from Insect Cells. Conjugated to His tag. Order Protein ABIN3095425 online. ... smt3ip1 Protein, fa03d07 Protein, wu:fa03d07 Protein, senp3 Protein, SUMO1/sentrin/SMT3 specific peptidase 3 Protein, SUMO/ ... SMT3IP1 Protein, SSP3 Protein, Ulp1 Protein, AA408656 Protein, Smt3ip Protein, Smt3ip1 Protein, ssp3 Protein, ... SENP3 Protein, Senp3 Protein, senp3 Protein, senp3b Protein, senp3.L Protein Background Protease that releases SUMO2 and SUMO3 ...

... but involve functionally relevant host-pathogen interactions associated with tandem and ankyrin repeat effector proteins. In ... but involve functionally relevant host-pathogen interactions associated with tandem and ankyrin repeat effector proteins. In ... This PTM is required for multiple interactions with SUMO-binding domain containing host proteins such as PCGF-5 and GGA1. ... outer membrane proteins, actin polymerization proteins, and a group of poly(G-C) tract containing proteins, which may be ...

pA104R is a highly conserved HU/IHF-like DNA-packaging protein identified in the ASFV nucleoid that appears to be profoundly ... The involvement of viral DNA-binding proteins in the regulation of virulence genes, transcription, DNA replication, and repair ... Molecular interaction between human SUMO-I and histone like DNA binding protein of Helicobacter pylori (Hup) investigated by ... ASFV Structural Proteins and Proteins Involved in Assembly. Up to 70 structural proteins have been identified from the ASFV ...

Therefore, we herein established a SARS-CoV-2 spike (S) protein-mediated cell-cell fusion assay and found that SARS-CoV-2 ... core of the HR1 and HR2 domains in the SARS-CoV-2 S protein S2 subunit, revealing that several mutated amino acid residues in ... series of lipopeptides derived from EK1 and found that EK1C4 was the most potent fusion inhibitor against SARS-CoV-2 S protein- ... The fusion proteins were isolated by Ni-affinity chromatography, and the SUMO tag was removed by Ulp1 enzyme (1:100 w/w) ...

Order PAK1 Proteins from many different species. Find the right product on antibodies-online.com. ... His-SUMO Tag). Reactivity Human Source Escherichia coli (E. coli) ... PAK1 Proteins by Protein Type. Find PAK1 Proteins with a specific Protein Type. The Protein Type listed below are among those ... Proteins. AW045634 Proteins. pak Proteins. pak-1 Proteins. PAK-1 Proteins. Paka Proteins. pakalpha Proteins. PAKalpha Proteins ...

Antibodies, ELISA kits, proteins, reagents. Order quickly and easily at antikoerper-online.de ... Fc fragment of IgG binding protein (FCGBP), Fc fragment of IgG binding protein (Fcgbp), A430096B05Rik, FC(GAMMA)BP Bezeichner ... His-SUMO Tag). Reaktivität Staphylococcus aureus Source Escherichia coli (E. coli) ... "The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier ...

Difficult-to-Express Proteins Market reached a valuation of US$ 3,8 Billion in 2021 and is expected to reach US$ 12.37 Billion ... Cell-free Protein Synthesis 7.3.2. Prokaryotic Expression Systems 7.3.3. SUMO Fusion System 7.3.4. Gene Fusion Systems 7.3.5. ... Disulfide-bonded Protein Expression 6.3.2. Membrane Protein Expression 6.3.3. Toxic Protein Expression 6.3.4. Target Protein ... Difficult-to-Express Proteins Market. Difficult-to-Express Proteins Market by Protein, Technology Type, Application & Region , ...

Locate proteins, assay kits, reagents, custom services. Get complete supplier details here. ... Need SARS-CoV-2 Envelope Protein for research? Find and compare commercial and governmental sources for immunological and ... SARS-CoV-2 Envelope Protein is a recombinant protein expressed in E. coli. Met1-Val75. N-terminal His and SUMO tags. Purity > ... COVID-19 protein, Protein COVID-19, Virus COVID-19 Protein, Virus COVID-19, Virus protein COVID-19, 2019-nCoV protein, Protein ...

Post-translational protein modification (Homo sapiens) * SUMOylation (Homo sapiens) * Processing and activation of SUMO (Homo ... SUMO is proteolytically processed (Homo sapiens) * SENP1,2,5 proteolytically process SUMO2 (Homo sapiens) * SUMO2(1-95) [ ...

SUMO2/3 Monoclonal Antibody recognizes proteins post-translational modifications SUMO2 and SUMO3. Tested in WB, IF, and IP ... Anti-SUMO-2/3 mouse monoclonal antibody was raised against full-length recombinant SUMO-2 protein (Uniprot: P61956) combined ... The antibody has been shown to recognize a wide range of SUMO-2/3-targeted proteins in HeLa cell lysate (Fig. 1B) and to detect ... Multiple bands indicate that TFII-I is SUMOylated by several SUMO-2/3 proteins. TFII-I has previously been reported to be a ...

The COOH-terminal A168-170 region of the giant sarcomeric protein titin interacts with muscle-specific RING finger-1 (MURF-1). ... These data, together with the observations that MURF-1s RING domain binds to the nuclear protein SUMO-3 (Dai and Liew, 2001) ... Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. ... Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. ...

... anti-nuclear matrix protein 2 (NXP2), and anti-SUMO-1 activating enzyme (SAE) autoantibodies. [42] ... Patients with antimelanoma differentiation-associated protein 5 antibodies had a significantly lower probability of achieving ... Increased plasma thrombospondin-1 (TSP-1) levels are associated with the TNF alpha-308A allele in children with juvenile ... 1, 2] Dystrophic calcinosis may complicate dermatomyositis and is most often observed in children and adolescents. ...

SARS-CoV-2 Spike Protein RBD (Delta B1.617.2 Variant), His-SUMO tag, HEK293 ... Youre reviewing:SARS-CoV-2 Spike Protein RBD (Delta B1.617.2 Variant), His-SUMO tag, HEK293 - orb1178864. Your Rating. 1 star ... SARS-CoV-2 Spike Protein RBD (Delta B1.617.2 Variant), His-SUMO tag, HEK293 ... SARS-CoV-2 Spike Protein RBD (Delta B1.617.2 Variant), His-SUMO tag, HEK293 ...

Protein ubiquitination patterns are an important component of cellular signaling. The WD-repeat protein WDR48 (USP1-associated ... In addition, WDR48 has a novel ancillary domain and a C-terminal SUMO-like domain encircling the USP46-bound ubiquitin. ... Protein ubiquitination patterns are an important component of cellular signaling. The WD-repeat protein WDR48 (USP1-associated ... Department of Structural Biology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: harris. ...