"STAT5 Transcription Factor" by people in this website by year, and whether "STAT5 Transcription Factor" was a major or minor ... "STAT5 Transcription Factor" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... STAT5 Transcription Factor*STAT5 Transcription Factor. *Factor, STAT5 Transcription. *Transcription Factor, STAT5 ... Below are the most recent publications written about "STAT5 Transcription Factor" by people in Profiles. ...

Our data show that O-GlcNAcylation of STAT5 is an important process that contributes to oncogenic transcription through ... Upon cytokine stimulation, STAT5 tyrosine phosphorylation (pYSTAT5) is transient, while in diverse neoplastic cells persistent ... O-GlcNAcylation of STAT5 could be required for nutrient sensing and metabolism of cancer cells. ... The expression of a mutated hyperactive gain-of-function (GOF) STAT5 without O-GlcNAcylation resulted in decreased tyrosine ...

STAT3 Transcription Factor / genetics * STAT3 Transcription Factor / metabolism * STAT5 Transcription Factor / metabolism ... Y510 efficiently mediated IL-21-induced phosphorylation of Stat1 and Stat3, but not of Stat5, and CD8(+) T cells from Stat1/ ... STAT1 Transcription Factor / genetics * STAT1 Transcription Factor / metabolism * ...

Nemetz C, Hocke GM (March 1998). "Transcription factor Stat5 is an early marker of differentiation of murine embryonic stem ... 2005). "Leukemia inhibitory factor as an anti-apoptotic mitogen for pluripotent mouse embryonic stem cells in a serum-free ... Lane MA, Chen AC, Roman SD, Derguini F, Gudas LJ (November 1999). "Removal of LIF (leukemia inhibitory factor) results in ... March 1997). "Factors predicting morbidity following hematopoietic stem cell transplantation". Bone Marrow Transplantation. 19 ...

Invitrogen Anti-Phospho-STAT5 alpha (Ser780) Polyclonal, Catalog # PA5-36688. Tested in Western Blot (WB), Immunohistochemistry ... STAT5 alpha is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family ... STAT5 alpha, along with STAT5 beta, were identified in mouse. The amino acid sequences of STAT5 alpha and STAT5 beta show 96% ... Protein Aliases: Mammary gland factor; mammary gland factor STAT5A; signal transducer and activator of transcription 5; Signal ...

Discovery of chromone-based inhibitors of the transcription factor STAT5. ChemBioChem 9 (5), S. 723 - 727 (2008) ... Hollis, A.; Sperl, B.; Graber, M.; Berg, T.: The Natural Product Betulinic Acid Inhibits C/EBP Family Transcription Factors. ... Berg, T.: Inhibition of transcription factors with small organic molecules. Current Opinion in Chemical Biology 12 (4), S. 464 ... Müller, J.; Schust, J.; Berg, T.: A high-throughput assay for signal transducer and activator of transcription 5b based on ...

Invitrogen Anti-STAT5 alpha Monoclonal (ST5a-2H2), Catalog # 13-3600. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF ... STAT5 alpha is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family ... STAT5 alpha, along with STAT5 beta, were identified in mouse. The amino acid sequences of STAT5 alpha and STAT5 beta show 96% ... Protein Aliases: Mammary gland factor; mammary gland factor STAT5A; signal transducer and activator of transcription 5; Signal ...

A, EPO stimulation of neurons does not activate the transcription factors STAT1, STAT3, and STAT5, as assessed by fEMSA. Shown ... In astrocytes the OGD enhanced the nuclear translocation of hypoxia-inducible factor 1 (HIF-1), the major transcription factor ... 2000) Occurrence of a transcription factor, signal transducer and activators of transcription 3 (STAT3) in the postsynaptic ... The expression of EPO is regulated by the transcription factor hypoxia-inducible factor-1 (HIF-1) (Semenza, 2000). Recent ...

These agonists all induced activation of the transcription factor STAT-5, which is a component of the intracellular pathway ... with evidence accumulating for certain transcription factors, such as Runx2, acting as a nexus for cross-talk. Full article ... Vascular Endothelial Growth Factor Induces CXCL1 Chemokine Release via JNK and PI-3K-Dependent Pathways in Human Lung Carcinoma ... STAT-5 activation occurred with either monophasic or biphasic kinetics for EPOα/DarbEPO and CERA, respectively. ESAs, likely ...

TRP120-interacting transcription factors include interleukin enhancer binding factor 3 (ILF3), a subunit of the nuclear factor ... Inhibition of PTPN2 causes Stat5 activation, increased production of IFN-γ, TNF-α, IL-12, and inducible nitric oxide synthase ( ... and elongation factor 1 alpha 1 (EF1A1), which is a component of transcription factor complex of T helper 1 cells (Maruyama et ... TRPs may regulate host gene transcription via their interactions with other host transcription factors and cofactors. ...

Once phosphorylated, Stat5 becomes an essential transcription factor which binds to the β-casein gene promoter. The presence of ... Once phosphorylated, Stat5 becomes an essential transcription factor which binds to the β-casein gene promoter. The presence of ... Stat5 has been characterized and shown to be encoded by two separate genes, Stat5a and Stat5b, which share over 90% identity at ... Stat5 has been characterized and shown to be encoded by two separate genes, Stat5a and Stat5b, which share over 90% identity at ...

STAT5 is an important transcription factor that is constitutively activated in various types of malignancies, including chronic ... negative regulation of sequence-specific DNA binding transcription factor activity - negative regulation of transcription from ... The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small ... sequence-specific DNA binding transcription factor activity - steroid hormone receptor activity - thyroid hormone receptor ...

STAT5, NFκB and ATF2, and master inflammatory transcription factors, in mouse mammary carcinomas [94]. Furthermore, cytokines ... and growth factors such as the vascular endothelial growth factor (VEGF) and the granulocyte colony-stimulating factor (G-CSF ... α12/13/RhoA/ROCK signaling causes activation of transcription factor ATF2 to induce further proinflammatory mediator production ... ATX-LPA axis has been studied in airway inflammation where protein kinase C δ (PKCδ) mediates LPA-induced NFκB transcription ...

STAT5 consists of two closely related family members, STAT5A and STAT5B, which exhibit 96% sequence homology and are ... STAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine ... STAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine ... The dimerized STAT5 translocates to the nucleus and binds to the STAT5 response element (TTCXXXGAA). STAT5 plays crucial ...

Differentiation of CD4+ T cells occurs by the transcription stimulation of transcription factor STAT5 which is activated by IL- ... This is characterized by type I interferons and transcription factors, IRF3, IRF7, and NF-κB (Uno and Ross, 2018; Tremblay et ... IL-2 initiates expression of Eomesodermin along with RunX3 transcription factors which causes the development of cytotoxic T ... 2011). Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8+ T cell immune responses against West Nile virus ...

miR-141 increases the CD44+ and CK5+ cell population, while reducing PR and Stat-5 levels, two important transcription factors ... Such down-regulation is linked to an increase in the transcription factor KLF4, as well as CD44 and CK5, with the subsequent de ... as well as other factors, including metalloproteases (MMPs), insulin growth factor (IGF), platelet growth factor (PDGF) ... The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single ...

... nuclear factor-kappaκB (NF-kappaκB), and signal transducer and activator of transcription-5 (STAT5), ultimately modulating the ... nuclear factor-kappaκB (NF-kappaκB), and signal transducer and activator of transcription-5 (STAT5), ultimately modulating the ... with other transcription factors, such as nuclear factor-kB, activator protein-1, p53, and signal transducers and activators of ... transcription factor; TFRE, transcription factor response element. ...

... serum response factor (SRF), POU domain, class 2, transcription factor 1 (POU2F1) regulatory transcription factor binding sites ... in particular STAT3 and STAT5, have been demonstrated to directly contribute to oncogenesis, in part, by stimulating ... Conserved transcription factor-binding sites within promoter regions of human RON genes were then searched. The expression data ... NF-κB, STAT5A, STAT3, PPAR-γ, SRF, POU2F1 regulatory transcription factor binding sites were identified in the MST1R gene ...

rOnIL-12 not only elevated the mRNA expression level Th1 cell-associated transcription factor T-bet in lymphocytes, but also ... Moreover, the mRNA and phosphorylation levels of STAT1, STAT3, STAT4 and STAT5 were enhanced by rOnIL-12. These findings will ... γ signaling in neurons results in differential activation of its downstream transcription factor, signal transducer and ... The transforming growth factor-ß-activated kinase 1 (TAK1) phosphorylation promotes inflammation occurrence. Meanwhile, TAK1 ...

... we show that this expression is inhibited in the presence of IL-4 and is regulated by the transcription factor STAT-5. Moreover ...

STAT5 Transcription Factor * Tumor Cells, Cultured Identity. Digital Object Identifier (doi) * https://doi.org/10.1038/leu. ... Dual inhibition of Jak2 and STAT5 enhances killing of myeloproliferative neoplasia cells. Academic Article * Authors Version ...

Transcription Factor Phospho Buffer Set enabled the otherwise challenging simultaneous detection of phosphorylated STAT5 and ... Transcription factors The BD Pharmingen™ Transcription Factor Buffer Set (Cat. No. 562574/562725) is designed for the staining ... Transcription factors. Intracellular flow cytometry enables the detection of transcription factors and associated proteins ... To further enable easy transcription factor detection, BD Biosciences has developed the BD Pharmingen™ Transcription Factor ...

... that ABL kinases modulated the expression of pro-bone metastasis factors via co-activation of the TAZ and STAT5 transcription ... were markedly decreased in ABL1/ABL2 knockdown cells were the Hippo pathway regulator TAZ and the STAT5A transcription factor. ... networks, and that expression of activated TAZ and STAT5 rescued metastatic activity in ABL1/ABL2-knockdown breast cancer cells ...

STAT5 Transcription Factor. Signal Transduction. T-Lymphocytes. Trans-Activators. Multigene Family Citazione ... a region that contains genes encoding the tumor necrosis factor (TNF) superfamily members TNF, LT-alpha and LT-beta. ... a region that contains genes encoding the tumor necrosis factor (TNF) superfamily members TNF, LT-alpha and LT-beta. ...

STAT5 Transcription Factor. 14. + 64. Aminoquinolines. 14. + 65. Etoposide. 13. + 66. Diatrizoate. 13. + ... STAT Transcription Factors. 23. + 34. NF-E2 Transcription Factor, p45 Subunit. 22. + ...

STAT5 Transcription Factor * Signal Transduction * Trans-Activators * Tumor Cells, Cultured Identity. PubMed Central ID * ...

STAT5 Transcription Factor 15% * Neoplasms 13% * Neutrophil Infiltration 11% * Bone Development 11% ...

STAT5 Transcription Factor 40% * Non-alcoholic Fatty Liver Disease 39% * Beckman Coulter MoFlo Astrios EQ Cell Sorter. Laskin, ...

GATA3, along with other transcription factors, STAT6, STAT5 and c-MAF, induce the transcription of IL4, IL5 and IL13. GATA3 is ... GATA3, along with other transcription factors, STAT6, STAT5 and c-MAF, induce the transcription of IL4, IL5 and IL13. GATA3 is ... The size of the lumen can also be affected by a variety of factors,including the transcription factor CCAAT/enhancer binding ... The balance between different members of the nuclear factor of activated T-cells (NFAT) family of transcription factors also ...