Protocols and Video Articles Authored by Bernd Fritzsch
Here we describe the cloning of the X. laevis orthologs of the SoxB2 family of transcription factors, sox14 and sox21. In situ ... The conservation of transcription factors and their regulators fits very well to the known or presumed mechanosensory ... Nov, 2008 , Pubmed ID: 19011097 Sox2 is a high-mobility transcription factor that is one of the earliest markers of developing ... 2008 , Pubmed ID: 18956331 The Sox family of transcription factors is thought to regulate gene expression in a wide variety of ...https://www.jove.com/author/Bernd_Fritzsch
Frontiers | New Neuronal Subtypes With a "Pre-Pancreatic" Signature in the Sea Urchin Stongylocentrotus purpuratus |...
Neurons and pancreatic endocrine cells have a common physiology and express a similar toolkit of transcription factors during ... Neurons and pancreatic endocrine cells have a common physiology and express a similar toolkit of transcription factors during ... It has been recently found that neuronal precursors sequentially express the transcription factors SoxB2, SoxC, and Brn1/2/4 ... the bHLH transcription factors neurogenins (10-12), and the homeobox transcription factor PDX1 (13, 14). ...https://www.frontiersin.org/articles/10.3389/fendo.2018.00650/full
SoxB2 in sea urchin development: implications in neurogenesis, ciliogenesis and skeletal patterning | EvoDevo | Full Text
We concluded that SoxB2 in sea urchins has a neurogenic function; however, this gene could have multiple roles in sea urchin ... We showed that SoxB2 is functionally conserved among deuterostomes and suggested that in S. purpuratus this gene acquired ... Herein, we show a comprehensive study of SoxB2 functions in sea urchins, in particular its expression pattern in a wide range ... Moreover, this work provides a detailed description of the phenotype of sea urchin SoxB2 knocked-down embryos, confirming its ...https://evodevojournal.biomedcentral.com/articles/10.1186/s13227-018-0094-1
Analysis of transcriptional targets of SOX9 during embryonic heart valve development reveals a critical network of...
SOX transcription factors are known to bind in complexes with other SOXs or other transcription factors in order to efficiently ... and 3 and SOXB2 containing SOX14 and SOX21. The SOXC subgroup contains SOX4, 11, and 12 and the SOXD group is comprised of SOX5 ... Transcription factor TGFβ- Transforming growth factor beta TSS- Transcriptional start site TTS- Transcription termination site ... that are targeted by SOX9 are transcription factors and suggests that SOX9 may be regulating a network of transcription factors ...https://open.library.ubc.ca/cIRcle/collections/ubctheses/24/items/1.0220645
SOX gene family - Wikipedia
SOX genes encode a family of transcription factors that bind to the minor groove in DNA, and belong to a super-family of genes ... In mouse and human the members of the groups are: SoxA: SRY SoxB1: SOX1, SOX2, SOX3 SoxB2: SOX14, SOX21 SoxC: SOX4, SOX11, ... transcription factors". Int. J. Biochem. Cell Biol. 39 (12): 2195-214. doi:10.1016/j.biocel.2007.05.019. PMC 2080623 . PMID ... "Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators". Dev. Biol. 227 ...https://en.wikipedia.org/wiki/SOX_gene_family
... and specific transcription factors and these transcription factors include the most widespread prokaryotic transcription ... transcriptional activators expressed in the CNS while SOXB2 genes seem to function as transcriptional repressors in the CNS ( ... transcription factors are homologous to the DAF-16 transcription factor of nematodes which functions in the cell cycle and ... universal binding factor) contains multiple HMG domains as does the human mitochondrial transcription factor mtTFA (Yang, 2002 ...http://bio.sunyorange.edu/updated2/GENETICS/5%20HMG%20BOX.htm