*  Melanopsin Is Expressed in PACAP-Containing Retinal Ganglion Cells of the Human Retinohypothalamic Tract | IOVS | ARVO Journals
Melanopsin: An opsin in melanophores, brain, and eye. Proc Natl Acad Sci USA. 1998;95:340-345. [CrossRef] [PubMed] ... Non-rod, non-cone photoreception in the vertebrates. Prog Retin Eye Res. 2002;21:507-527. [CrossRef] [PubMed] ... Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science. 1999;284:505-507. [CrossRef] [PubMed] ... Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors. Science. 1999;284:502-504. [CrossRef] [ ...
  http://iovs.arvojournals.org/article.aspx?articleid=2124147
*  Adaptation of pineal expressed teleost exo-rod opsin to non-image forming photoreception through enhanced Meta II decay. -...
We have used the presence of distinct rod opsin genes specialized to either image-forming (retinal rod opsin) or non-image- ... in other aspects exo-rod opsins exhibit a behavior that is quite distinct from the cardinal features of the rod opsin family. ... Our findings suggest that the requirements of non-image-forming photoreception have lead exo-rod opsin to adopt a ... forming (pineal exo-rod opsin) photoreception in ray-finned fish (Actinopterygii) to gain a unique insight into this problem. A ...
  https://www.ndcn.ox.ac.uk/publications/127156
*  Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light. - Physiology, Anatomy and Genetics
To investigate these contradictory findings and to dissect the relative contribution of pRGCs and rods/cones, we assessed the ... These responses involve melanopsin (OPN4)-expressing photosensitive retinal ganglion cells (pRGCs) in addition to rods and ... Rod Opsins, Sleep, Suprachiasmatic Nucleus, Time Factors ... in addition to rods and cones. Nocturnal light exposure in ... To investigate these contradictory findings and to dissect the relative contribution of pRGCs and rods/cones, we assessed the ...
  https://www.dpag.ox.ac.uk/publications/627038
*  Proceedings of The Physiological Society | Physiological Society
... which carry a human red cone opsin coding sequence in place of the native medium-wavelength cone opsin. The resultant shift in ... In addition to rod and cone photoreceptors, the retina contains a subset of retinal ganglion cells that are rendered ... These data reveal that while cones (and rods) drive fast transient responses to light onset and offset, melanopsin contributes ... of each photoreceptor was initially examined by describing stimulus-response relationships for transgenic mice lacking rods and ...
  http://www.physoc.org/proceedings/abstract/Proc%20Physiol%20Soc%2019PC235
*  Plus it
Ectopic expression of the Rh5 and Rh6 opsin genes.Flies expressing the Rh5 opsin gene in the R1-R6 photoreceptor cells of ninaE ... Dopamine-dependent sensitization of rod bipolar cells by GABA is conveyed through wide-field amacrine cells ... 6,LW clade). As with Rh5, Rh6 shares a greater similarity (,55%) with opsins of the LW group than with otherDrosophila opsins. ... This work completes the characterization of all of the known, cloned, Drosophila opsin genes. Although more opsin genes may ...
  http://www.jneurosci.org/content/19/24/10716
*  Spectral tuning of the long wavelength-sensitive cone pigment in four Australian marsupials.
0/RNA, Messenger; 0/Rod Opsins; 0/long-wavelength opsin From MEDLINE®/PubMed®, a database of the U.S. National Library of ... Here, we have studied and compared the LWS opsins in four Australian marsupials: two diprotodonts and two polyprotodonts. ...
  http://www.biomedsearch.com/nih/Spectral-tuning-long-wavelength-sensitive/16859843.html
*  Frontiers | Palmitic Acid: Physiological Role, Metabolism and Nutritional Implications | Physiology
2010). Palmitoylation stabilizes unliganded rod opsin. Proc. Natl. Acad. Sci. U.S.A. 107, 8428-8433. doi: 10.1073/pnas. ...
  https://www.frontiersin.org/articles/10.3389/fphys.2017.00902/full
*  The effect of elevated hydrostatic pressure on the spectral absorption of deep-sea fish visual pigments | Journal of...
Hope, A. J., Partridge, J. C., Dulai, K. S. and Hunt, D. M. (1997). Mechanisms of wavelength tuning in the rod opsins of deep- ... some 30 rod opsin sequences) that are already available from diverse deep-sea fish taxa (Hope et al., 1997; Hunt et al., 2001 ... However, the preciseλ max of rod pigment measurements shows little variation with method (Douglas et al., 1995) and extract ... Nevertheless, the observed shift inλ max may be indicative of changes in opsin conformation that could have other consequences ...
  http://jeb.biologists.org/content/209/2/314
*  Mouse Cone Photoreceptors Co-express Two Functional Visual Arrestins
8A), ~ 2-fold faster than transgenic S-opsin recovery in Arr1−/− rods (Chan et al., 2007). In contrast, in the absence of Arr1 ... Much faster decay of photoactivated, phosphorylated cone- than rod- opsins. Only one photoreceptor-specific GRK, Grk1 (alias ... 5). Finally, dim-flash responses of cones driven by either S-opsin or M-opsin (Fig. 6) exhibit the same requirement for an ... 1 ratio to cone opsin, an approximately 7-fold higher ratio than Arr1 to rhodopsin in rods (Table 1; Supplement Table 1S). As ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2610856/
*  Human melanopsin has a λmax ≈ 479 nm | Proceedings of the Royal Society of London B: Biological Sciences
The success of this strategy was confirmed using human rod opsin, whose native G-protein (Gt) shares most homology with Gi/o ... As predicted, light induced a marked and prolonged reduction in cAMP in cells expressing human rod opsin (figure 1e). This was ... n ≥ 4 except human rod opsin (Rh1), n = 2. (h) There was a significant difference in peak of luminescence immediately following ... Not only was the human melanopsin-driven calcium response insensitive to pertussis toxin (data not shown), but also rod opsin, ...
  http://rspb.royalsocietypublishing.org/content/280/1759/20122987?cited-by=yes&legid=royprsb
*  Altered Expression of Retinal Molecular Markers in the Canine RPE65 Model of Leber Congenital Amaurosis | IOVS | ARVO Journals
Rod opsin antibodies were used to assess rod photoreceptors. The expression of rod opsin was limited to the rod OS of the wt ... Antibodies against different opsin classes (rod opsin and M/L and S opsin) and hCAR were used to evaluate the rod and cone ... Rod opsin antibodies labeled rod OS in the wt retinas, but in the mutant retinas opsin was also delocalized into the ... Rod opsin antibodies labeled rod OS in the wt retinas, but in the mutant retinas opsin was also delocalized into the ...
  https://iovs.arvojournals.org/article.aspx?articleid=2127419
*  Plus it
1991) Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice. Neuron 6:201-210. ...
  http://www.jneurosci.org/content/16/21/6908
*  Gene Duplication and Spectral Diversification of Cone Visual Pigments of Zebrafish | Genetics
... green or the rod-opsin-like cone-opsin group (RH2), and red-green or the long-to-middle-wave-sensitive cone-opsin group (LWS/ ... Our study on the zebrafish cone opsin genes together with our previous study on the rod opsin gene (RH1;Hamaokaet al. 2002) ... Vertebrate opsins have been classified into five phylogenetic groups: rod opsin or the rhodopsin group (RH1), ultraviolet-blue ... rod opsin). The quantitative RT-PCR revealed a considerable difference among the opsin genes in the expression level in the ...
  http://www.genetics.org/content/163/2/663
*  A. anableps and J. onca opsin expression | Biology Letters
1998 Switch in rod opsin gene expression in the European eel, anguilla anguilla (L.). Proc. R. Soc. Lond. B 265, 869-874. doi: ... In J. onca, sws1, sws2b, rh2-2 and rh2-1 opsins were expressed throughout the retina; while lws opsins were not expressed in ... We used in situ hybridization with opsin riboprobes to map cone opsin expression in the retina of A. anableps. This was ... opsin gene sequence) and phenotype (wavelength of maximum sensitivity), much work has been done to correlate opsin gene ...
  http://rsbl.royalsocietypublishing.org/content/early/2011/07/08/rsbl.2011.0582
*  Vitamin A Plays an Essential Role in Setting the Circadian Rhythm and Allowing Good Sleep - The Weston A. Price Foundation
In rods, the opsin protein is called rhodopsin (rod-opsin). In cones, there are three opsins, specific to red, green, or blue ... In more casual language, these proteins are named after the colors they absorb ("red opsin," "green opsin," and "blue opsin"); ... In all cases, a metabolite of vitamin A is bound to a protein of the opsin family. Light enters the eye, makes its way to the ... Apart from rods and cones, there are cells in our retina that are responsible for setting our circadian rhythm, known as ...
  https://www.westonaprice.org/vitamin-plays-essential-role-setting-circadian-rhythm-allowing-good-sleep/
*  Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors | JCB
We detected no expression of rod opsin (Rho), rod transducin (Gnat1), or the rod cyclic nucleotide-gated channel (Cnga1) in ... b) Rod-specific mRNAs were absent or significantly down-regulated in Nrl−/− and Nrl−/−/Rds−/− retinas. Rhodopsin (Rho), rod- ... The WT retina was labeled by rhodopsin (green) and S-opsin (red), demonstrating the presence of both rods and cones, ... CC, connecting cilium; CIS, cone inner segment; COS, cone outer segment; RIS, rod inner segment; ROS, rod outer segment. Bars, ...
  http://jcb.rupress.org/content/173/1/59
*  WO1999053961A1 - Peptides for efficient gene transfer - Google Patents
Rod opsin mRNA-specific ribozyme compositions and methods for the treatment of retinal diseases ... the peptide undergoes a conformational change from a random coil to an extended rod that inserts into the endosome, resulting ...
  https://patents.google.com/patent/WO1999053961A1/en
*  Functional and Cellular Responses in a Novel Rodent Model of Anterior Ischemic Optic Neuropathy | IOVS | ARVO Journals
... rod opsin is an indicator of outer retinal cell layer function and photoreceptor damage. 19 ... as measured by the photoreceptor-specific gene opsin mRNA, between induction and 7 days after induction (Fig. 7E ; opsin; 0 ... These are seen in Table 1 . The studied genes c-fos, brn3.2, HSP70-1/2, opsin, HSP86, and HSP84 were chosen because: (1) c-fos ... Opsin. U22180. For: TGG TGC GCA GCC CCT TTG AGC. 63. 385. 16. 3:2. ...
  https://iovs.arvojournals.org/article.aspx?articleid=2182114
*  Downloade Bücher "Outdoors & Nature - Hunting & Fishing". E-Book Bibliothek B-OK.org
Mechanisms of wavelength tuning in the rod opsins of deep-sea fishes. Hope, A. J., Partridge, J. C., Dulai, K. S., Hunt, D. M. ... Spectral tuning and molecular evolution of rod visual pigments in the species flock of cottoid fish in Lake Baikal. David M. ...
  http://de.booksc.org/Outdoors-%26-Nature-Hunting-%26-Fishing-cat258
*  Fish disease models and uses thereof - Goldsmith, Paul
An example is the transgenic line expressing GFP in rod photoreceptors, by placing the rod opsin promoter upstream of eGFP ( ... For example, thyroxine is known to switch photoreceptor fate towards cones and away from rods [Kelley, 1995], whilst rods do ... 30(3):725-36). In another embodiment, the promoter of the disease gene is replaced with the opsin promoter (Kennedy et al., ( ... rod photoreceptor, cone photoreceptor, ganglion cell, glial cell, horizontal cell, bipolar cell and amacrine cell. ...
  http://www.freepatentsonline.com/y2006/0115895.html
*  Frontiers | The Biological Mechanisms and Behavioral Functions of Opsin-Based Light Detection by the Skin | Ecology and...
... including many non-rod/non-cone ocular cells, the pineal complex, the deep brain, and the skin. Indeed, many of the ... Indeed, many of the photopigments (an opsin linked to a light-sensitive 11-cis retinal chromophore) that mediate color vision ... photopigments (an opsin linked to a light-sensitive 11-cis retinal chromophore) that mediate color vision in the eyes of ... including many non-rod/non-cone ocular cells, the pineal complex, the deep brain, and the skin. ...
  https://www.frontiersin.org/articles/10.3389/fevo.2016.00106/full
*  Induction of sleep by acute light in Opa1+/+ and Opa1+/ | Open-i
Induction of sleep by acute light in Opa1+/+ and Opa1+/− mice.(A) The average immobility-defined sleep is plotted against zeitgeber time in a normal 12∶12 h
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3569441_pone.0056350.g004&req=4
*  British Library EThOS: Pharmacological therapies for rhodopsin retinitis pigmentosa
Whereas wild-type rod opsin translocated to the plasma membrane of the cells, P23H mutant rod opsin misfolded was retained in ... In cells co-expressing wild-type and P23H rod opsin these compounds restored the normal processing of the wild-type protein, ... Mutations in the visual pigment protein rod opsin are the most common cause of autosomal dominant retinitis pigmentosa (ADRP) ... that some of the gain of function and dominant-negative properties of mutant misfolded rod opsin can be manipulated. The ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498505
*  Multiple transcripts of rh1 occur in the Australian lun | Open-i
However, the relationship between lungfish, the coelacanth and tetrapods could not be absolutely determined from opsin ... However, the relationship between lungfish, the coelacanth and tetrapods could not be absolutely determined from opsin ... the coelacanth and tetrapods could not be absolutely determined from opsin phylogeny, supporting an unresolved trichotomy ... the coelacanth and tetrapods could not be absolutely determined from opsin phylogeny, supporting an unresolved trichotomy ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2194722_1471-2148-7-200-2&req=4
*  RHO Gene - GeneCards | OPSD Protein | OPSD Antibody
Opsin 2, Rod Pigment 2 3 * Opsin-2 3 4 * OPN2 3 4 ... Mature Rod Cells Outer Nuclear Layer * Rod Precursor Cells ... Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) ... The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light ... rhodopsin,G protein coupled receptor superfamily,visual pigment of the rod cells of retina *RHO ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=RHO