*  ristocetin (CHEBI:85129)
... is a heterodetic cyclic peptide (CHEBI:24533) ristocetin (CHEBI:85129) is a macrocycle (CHEBI:51026) ... ristocetin (CHEBI:85129) has role antibacterial drug (CHEBI:36047) ristocetin (CHEBI:85129) has role antimicrobial agent (CHEBI ... ristocetin (CHEBI:85129) has role platelet-activating factor receptor agonist (CHEBI:75414) ristocetin (CHEBI:85129) is a ... CHEBI:85129 - ristocetin. Main. ChEBI Ontology. Automatic Xrefs. Reactions. Pathways. Models. .gridLayoutCellStructure { min- ...
  https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A85129
*  Ristocetin - Wikipedia
Platelet agglutination caused by ristocetin can occur only in the presence of von Willebrand factor multimers, so if ristocetin ... Thus, the ristocetin cofactor activity depends only upon high-molecular multimers of the factor present in circulating plasma. ... Ristocetin is an antibiotic, obtained from Amycolatopsis lurida, previously used to treat staphylococcal infections. It is no ... In all forms of the ristocetin assay, the platelets are fixed in formalin prior to the assay to prevent von Willebrand's factor ...
  https://en.wikipedia.org/wiki/Ristocetin
*  Ristocetin-induced platelet aggregation - Wikipedia
Ristocetin cofactor assay uses platelet-poor plasma (with vWF but no platelets) and adds ristocetin and exogenous formalin- ... consistent with ristocetin cofactor assay results) Type 2B vWD: hyperactive agglutination occurs (when the ristocetin cofactor ... consistent with ristocetin cofactor assay results) Type 3 vWD: no agglutination occurs (consistent with ristocetin cofactor ... "Studies on the mechanism of ristocetin-induced platelet adhesion. Effects of structural modification of ristocetin and ...
  https://en.wikipedia.org/wiki/Ristocetin-induced_platelet_aggregation
*  On the Streptomyces albus G DD carboxypeptidase mechanism of action of penicillin, vancomycin, and ristocetin - Leyh-Bouille...
Vancomycin and ristocetin are shown to inhibit the hydrolysis of sensitive peptides by the Streptomyces albus G D-alanyl-D ... On the Streptomyces albus G DD carboxypeptidase mechanism of action of penicillin, vancomycin, and ristocetin. ... en] carboxypeptidases ; chemical phenomena ; chemistry ; penicillins ; ristocetin ; streptomyces ; vancomycin ; antagonists & ...
  http://orbi.ulg.ac.be/handle/2268/91733
*  AJvW-2, an Anti-vWF Monoclonal Antibody, Inhibits Enhanced Platelet Aggregation Induced by High Shear Stress in Platelet-Rich...
Ristocetin cofactor activity was determined in PPP from patients and controls by measuring the platelet aggregation induced by ... Maximal ristocetin cofactor activity in a plasma sample pooled from 100 healthy donors was defined as 100%. ... Plasma Levels of vWF Antigen and Ristocetin Cofactor Activity. The plasma level of vWF antigen was significantly higher in the ... We observed the following: (1) 1.7-fold higher plasma levels of vWF and ristocetin cofactor activity in UAP patients and (2) ...
  http://atvb.ahajournals.org/content/19/4/877
*  Heme Flashcards by Stuart Abel | Brainscape
Abnormal ristocetin test (no aggregation of platelets with addition of ristocetin). 156 ...
  https://www.brainscape.com/flashcards/heme-553791/packs/1099175
*  Hematology/Oncology Flashcards by Andrew Rivera | Brainscape
Ristocetin activates vWF to bind Gp1b. Failure of agglutination with ristocetin assay occurs in von Willebrand disease and ... Diagnosed in most cases by ristocetin cofactor assay (lower agglutination is diagnostic). Tx = desmopressin, which releases vWF ...
  https://www.brainscape.com/flashcards/hematology-oncology-3698361/packs/5585230
*  Management of Acute Abnormal Uterine Bleeding in Nonpregnant Reproductive-Aged Women - ACOG
... including von Willebrand-ristocetin cofactor activity, von Willebrand factor antigen, and factor VIII (2, 5). Based on the ... including consultation with a hematologist and testing for von Willebrand factor and ristocetin cofactor. ...
  https://www.acog.org/Clinical-Guidance-and-Publications/Committee_Opinions/Committee_on_Gynecologic_Practice/Management_of_Acute_Abnormal_Uterine_Bleeding_in-Nonpregnant-Reproductive-Aged-Women
*  Diagnosis and treatment - Mayo Clinic
Ristocetin cofactor activity. This test measures how well the von Willebrand factor works in your clotting process. Ristocetin ...
  https://www.mayoclinic.org/diseases-conditions/von-willebrand-disease/diagnosis-treatment/drc-20354984?p=1
*  Free Laboratory Science Flashcards about Coagulation Studies
Ristocetin. Decreased production of prostacyclin is a key indicator of the secondary condition due to drugs or infx is ... Thrombin and Ristocetin. Glanzmann's thrombasthenia is a deficiency in glycoprotein contents, all aggregation studies will show ...
  https://www.studystack.com/flashcard-193941
*  PPT - Failure of C oagula tion PowerPoint Presentation - ID:2398045
Failure of C oagula tion. MUDr. Tomáš Stopka Ph.D. and colleagues from the Institute of Pathophysiology, Charles University. Pl a n. Coagulation Methods DIC T h erap y Presentation. I. Coagulation. Initiating the Clotting Process Slideshow 2398045 by eliora
  https://www.slideserve.com/eliora/failure-of-c-oagula-tion
*  Platelet Disorders: Overview of Platelet Disorders, Pathophysiology of Platelet Disorders, Autoimmune Thrombocytopenias
In this variant, the ristocetin cofactor activity and ristocetin-induced platelet aggregation are decreased but the vWf antigen ... Platelets do not aggregate to any agents except ristocetin. The more severe type I results from a complete absence of the GP ... The dose of vWf concentrate is calculated based on ristocetin cofactor units (usual dose is 50-100 U/kg). The factor VIII level ... Ristocetin-induced platelet aggregation correlates with the platelet-aggregating activity of the von Willebrand protein. The ...
  https://emedicine.medscape.com/article/201722-overview
*  Diagnosis and Management of Von Willebrand Disease: Guidelines for Primary Care - - American Family Physician
Pregnant women with VWD who have factor VIII or VWF ristocetin cofactor (VWF:RCo) levels of less than 50 IU per dL, or a ... NA = not applicable; RIPA = ristocetin-induced platelet aggregation; VWD = von Willebrand disease; VWF = von Willebrand factor ... NA = not applicable; RIPA = ristocetin-induced platelet aggregation; VWD = von Willebrand disease; VWF = von Willebrand factor ...
  https://www.aafp.org/afp/2009/1201/p1261.html
*  Type 3 von Willebrand Disease Summary Report | CureHunter
RistocetinIBA 03/01/2002 - "Coagulation studies demonstrated undetectable levels of ristocetin-induced platelet aggregation ( ... ristocetin cofactor activity (vWF:RCo) and ristocetin-induced platelet agglutination (RIPA). ". 11/01/2005 - "Recessive type 3 ... ristocetin cofactor activity (vWF:RCo) and ristocetin-induced platelet agglutination (RIPA). ". ... 03/01/2002 - "Coagulation studies demonstrated undetectable levels of ristocetin-induced platelet aggregation (RIPA), von ...
  http://www.curehunter.com/public/keywordSummaryD056729-Type-3-von-Willebrand-Disease.do
*  Patent US20020028517 - Novel method of platelet function analysis using platelet count - Google Patents
4. Ristocetin: 1 ml of blood dilution from II+60 ul ristocetin solution ... ristocetin, arachidonic acid, and the like. They may be used as aggregating agents and agonists in the present invention as ... ristocetin, collagen, etc.) in a traditional platelet aggregometer. Aggregometry works on a simple photometric principle and ... and ristocetin in specific concentrations would provide differing aggregation responses such that a differential diagnosis may ...
  http://www.google.com/patents/US20020028517?dq=60/310,746
*  Thrombosis Therapy: Focus on Antiplatelet Agents | OMICS International
collagen and ristocetin inhibitor -. Oral Phase I completed -. Elinogrel (PRT060128; Novartis) Thienopyridine P2Y12 same as ... DZ-697b is a newer orally antiplatelet agent that inhibits collagenor ristocetin-induced platelet activation. Although further ... mAb against GPIbα; inhibit both ristocetin- and botrocetin-induced platelet aggregation Preclinical ...
  https://www.omicsonline.org/open-access/thrombosis-therapy-focus-on-antiplatelet-agents-2332-0672.1000103.php?aid=16500
*  Thrombocytopenia in pregnancy - The Clinical Advisor
Although vWF antigen levels rise in pregnancy, the increased sensitivity to low dose ristocetin that characterizes type II B ...
  http://www.clinicaladvisor.com/hematology/thrombocytopenia-in-pregnancy/article/597846/
*  Table of Contents - June 28, 1975, 2 (5973) | The BMJ
Letter: Inhibition of ristocetin-induced platelet aggregation by haemaccel. Br Med J 1975; 2 :750 (Published 28 June 1975) ...
  http://www.bmj.com/content/2/5973
*  Von Willebrand Disease | National Heart, Lung, and Blood Institute (NHLBI)
Von Willebrand factor ristocetin (ris-to-SEE-tin) cofactor activity. This test shows how well your von Willebrand factor works. ...
  https://www.nhlbi.nih.gov/health-topics/von-willebrand-disease
*  The Bacillus subtilis GntR Family Repressor YtrA Responds to Cell Wall Antibiotics
Structure of ristocetin A in complex with a bacterial cell-wall mimetic. Acta Crystallogr. D Biol. Crystallogr. 65:832-838 [PMC ... 2). Genes in the ytrA and ywoB operons clustered tightly, demonstrating induction by bacitracin, vancomycin, ristocetin, and ... 0.5 μg/ml ristocetin, 10 min; 2 μg/ml vancomycin, 10 min; 5 μg/ml RAM, 10 min; 1 μg/ml MOE, 20 min; 64 μg/ml polymyxin B, 10 ... and ristocetin bind to the terminal d-Ala-d-Ala of the pentapeptide side chain (21, 30). The glycolipodepsipeptide ramoplanin ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3187214/?lang=en-ca