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*  Socio-economic status, life style, biological risk factors and cardiovascular diseases.] - RIVM
The goal of this study was to describe socio-economic differences in (risk factors for) cardiovascular diseases and in clustering of risk factors. For this investigation data from the Netherlands Monitoring Risk Factor Project were used. The study population consists of 36,588 men and women, aged 20 - 60 years. Men and women with lower socio-economic status had a less healthy lifestyle (smoking, alcohol consumption and physical activity) and a higher prevalence of biological risk factors (obesity, hypercholesterolemia and hypertension). The prevalence of cardiovascular diseases was lower for the higher educated than for the lower educated. The differences could to a certain degree be explained by the differences in life style and in biological risk factors ...
  http://www.rivm.nl/en/Documents_and_publications/Scientific/Reports/1993/mei/Socio_economic_status_life_style_biological_risk_factors_and_cardiovascular_diseases
*  SISA - Società Italiana per lo Studio dell'Aterosclerosi - Fasting blood glucose and the risk of stroke and myocardial...
BACKGROUND: Although diabetes is a well-known risk factor of atherosclerotic cardiovascular diseases, the cardiovascular disease risk of glycemia below the current diabetic threshold remains uncertain. METHODS AND RESULTS: A total of 652,901 Korean men aged 30 to 64 years from the Korean National Health Insurance System were categorized into 8 groups by fasting blood glucose (FBG) level at baseline and were followed up for cardiovascular diseases occurrence during 1992-2001. Over the follow-up period of 8.8 years, 10,954 stroke and 3766 myocardial infarction events occurred. In age-adjusted analyses, there was evidence of linear associations between FBG and myocardial infarction, ischemic stroke, and intracerebral hemorrhagic stroke. However, with additional adjustment for socioeconomic position, behaviors, and other cardiovascular disease risk factors, the associations with myocardial infarction and intracerebral hemorrhagic stroke were ...
  http://www.sisa.it/index.php?class=Comp&className=Content&op=Show¶m=cid,53,preview,0
*  Reduction of preventable risk factors could reduce cardiovascular-related deaths - Healthcanal.com : Healthcanal.com
Led by Shivani Patel, PhD, researcher in the Hubert Department of Global Health at Rollins School of Public Health, the team studied data from the Behavioral Risk Factor Surveillance System (BRFSS) national surveys from 2009 to 2010. The goal was to determine the extent to which national cardiovascular mortality could be expected to decrease if all states were successful at reducing those risk factor levels to specified target levels.. Cardiovascular disease remains a leading cause of death nationally. The top five leading preventable risk factors for heart disease are elevated cholesterol, diabetes, hypertension, obesity and smoking. The fraction of cardiovascular deaths that could have been prevented in 2009 to 2010 were reported under two scenarios: complete elimination of risk factors, and a more realistic goal of reduction of risk factors to the best achieved levels in ...
  https://www.healthcanal.com/blood-heart-circulation/heart-disease/64931-reduction-of-preventable-risk-factors-could-reduce-cardiovascular-related-deaths.html
*  Circulating Osteoglycin and NGAL/MMP9 Complex Concentrations Predict 1-Year Major Adverse Cardiovascular Events After Coronary...
This study investigated the associations between circulating plasma biomarkers, which were previously identified by proteomics or immunohistochemistry experiments in human carotid plaques and adverse cardiovascular outcome in patients undergoing coronary angiography. The prognostic value of the majority of these proteins, including OGN and NGAL/MMP9 complex, for MACE had not yet been investigated. Higher circulating OGN and NGAL/MMP9 complex levels were associated with incident MACE during the first year of follow-up, independently of conventional cardiovascular risk factors. Adding OGN or NGAL/MMP9 to a model containing conventional cardiovascular risk factors improved risk classification and discriminatory ability, although the latter was not statistically significant. These associations with incident MACE and improvements in predictive ability were independent of CRP.. In previous proteomic experiments, we have identified ...
  http://atvb.ahajournals.org/content/34/5/1078
*  Cardiovascular Risk Factors in an Ambulatory Urban Patient Population - Full Text View - ClinicalTrials.gov
According to WHO estimations, cardiovascular diseases (CVDs) are the number one cause of death globally. More people die annually from CVDs than from any other cause. An estimated 17.5 million people died from CVDs in 2005, representing 30% of all global deaths. Of these deaths, an estimated 7.6 million were due to coronary heart disease and 5.7 million were due to stroke.. Over 80% of CVD deaths take place in low- and middle-income countries and occur almost equally in men and women. In Paraguay, prevalence of classic risk factors, as well as new ones, like the metabolic syndrome are not completely known.. Government health policies in industrialized countries are focusing on programs to modify cardiovascular risk factors. In developing countries, prevention of coronary heart disease and stroke through modification of cardiovascular risk factors are not playing a large role at the moment.. The aim of this ...
  https://clinicaltrials.gov/ct2/show/NCT00486993?term=acute+coronary+syndrome&lup_s=02%2F15%2F2014&lup_d=14&show_rss=Y&sel_rss=mod14
*  The Roles of Physical Activity and Electric Blankets in Brea... : Epidemiology
Breast cancer is a devastating disease. The specter of breast cancer frightens most women because it causes substantial morbidity and mortality despite our ever-increasing ability to provide earlier diagnosis and improved treatments. Breast cancer incidence rates are increasing worldwide, yet the relatively well-established risk factors account for no more than 50 to 55% of the breast cancer risk of westernized populations. 1-3 As a result, breast cancer epidemiologists have continued to search for additional risk factors, particularly lifestyle and environmental exposures, that are amenable to intervention.. Ovarian hormones, and particularly estrogens, play a major role in the development of breast cancer. 4 In fact, most accepted breast cancer risk factors can be interpreted as surrogate measures of a woman's cumulative exposure to estrogen and possibly, progesterone. These ...
  http://journals.lww.com/epidem/Fulltext/2001/11000/The_Roles_of_Physical_Activity_and_Electric.2.aspx
*  Abstract P204: Coronary Heart Disease Risk Factors and Perceived Risk among Overweight and Obese Adults | Circulation
Background: Obesity is a known risk factor for coronary heart disease (CHD) and plays a role in other CHD risk factors including dyslipidemia, hypertension, and type 2 diabetes mellitus. With nearly two-thirds of the adult US population being overweight and obese, it is important to know how these individuals perceive their CHD risk.. Objective: The purpose of this study was to examine the associations between self-reported CHD risk factors and perceived CHD risk among overweight and obese adults.. Methods: Demographic data, CHD risk factors, and perceived lifetime CHD risk were collected via electronic surveys using REDCap, an Internet-based data capture tool, of overweight and obese adults enrolled in a Weight Loss Research Registry. CHD risk factors were assessed using an investigator-developed survey of ...
  http://circ.ahajournals.org/content/129/Suppl_1/AP204.short?rss=1
*  Epidemiological association synonyms, epidemiological association antonyms - FreeThesaurus.com
Synonyms for epidemiological association in Free Thesaurus. Antonyms for epidemiological association. 106 synonyms for association: group, company, club, order, union, class, society, league, band, set, troop, pack, camp, collection, gathering, organization.... What are synonyms for epidemiological association?
  http://www.freethesaurus.com/epidemiological+association
*  Job Strain and Cardiovascular Disease Risk Factors : Meta-Analysis of Individual-Participant Data from 47,000 Men and Women
Background: Job strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain - heart disease association. Methodology and Principal Findings: We pooled cross-sectional, individual-level data from eight studies comprising 47,045 participants to investigate the association between job strain and the following cardiovascular disease risk factors: diabetes, blood pressure, pulse pressure, lipid fractions, smoking, alcohol consumption, physical inactivity, obesity, and overall cardiovascular disease risk as indexed by the Framingham Risk Score. In age-, sex-, and socioeconomic status-adjusted analyses, compared to those without job strain, people with job strain were more likely to have diabetes (odds ratio 1.29; 95% CI: ...
  http://miun.diva-portal.org/smash/record.jsf?pid=diva2:654801
*  Impact of preventable risk factors on stroke in the EPICOR study: does gender matter?
Downloadable (with restrictions)! Abstract Objectives The effect of modifiable stroke risk factors in terms of prevented cases remains unclear due to sex-specific disease rate and risk factors prevalence. Our aim was to estimate their impact on stroke by gender through population-attributable fraction (PAF), preventive fraction (PF) and their combination in EPIC-Italian cohort. Methods 43,976 participants, age 34-75, and free of cardiovascular disease at baseline (1993-1998) were followed up for almost 11 years. Adjusted hazard ratios and PAF were estimated using Cox models. Results We identified 386 cases. In males, the burden for stroke was 17% (95% CI 4-28%) for smoking and 14% (95% CI 5-22%) for alcohol consumption. In females, hypertension was carrying the biggest burden with 18% (95% CI 9-26%) followed by smoking 15% (95% CI 7-22%). Their combination was 46% (95% CI 32-58%) in males and 48% (95% CI 35-59%) in females. PF for current ...
  https://ideas.repec.org/a/spr/ijphth/v62y2017i7d10.1007_s00038-017-0993-2.html
*  Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes with Several Cardiovascular Risk Factors |...
Rationale: Coronary Artery Disease (CAD) is a critical determinant of morbidity and mortality. Previous studies have identified several cardiovascular disease (CVD) risk factors, which may partly arise from a shared genetic basis with CAD, and thus be useful for discovery of CAD genes. Objective: We aimed to improve discovery of CAD genes, and inform the etiologic relationship between CAD and several CVD risk factors using a shared polygenic signal-informed statistical framework. Methods and Results: Using genome-wide association studies (GWAS) summary statistics and shared polygenic pleiotropy-informed conditional and conjunctional false discovery rate (FDR) methodology, we systematically investigated genetic overlap between CAD and 8 traits related to CVD risk factors: low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, triglycerides (TG), type 2 diabetes (T2D), ...
  http://circres.ahajournals.org/content/early/2015/10/20/CIRCRESAHA.115.306629
*  Pericardial Fat, Visceral Abdominal Fat, Cardiovascular Disease Risk Factors, and Vascular Calcification in a Community-Based...
Intrathoracic and pericardial fat were normally distributed. Age-adjusted Pearson correlations between intrathoracic and pericardial fat were performed with metabolic risk factors and adiposity traits. Multivariable linear and logistic regression was used to assess the significance of covariate-adjusted cross-sectional relations between continuous and dichotomous metabolic risk factors and intrathoracic and pericardial fat. The covariate-adjusted risk factor per 1-SD increase of adipose tissue was estimated for continuous variables; for dichotomous risk factors, the odds ratio of the risk factor prevalence per 1-SD increase in adipose tissue was estimated. Sex interactions were tested. Covariates included age, smoking (current/former/never smoker), alcohol use (,14 drinks/week [men] or ,7 drinks/week [women]), menopausal status, and hormone replacement therapy. Lipid ...
  http://circ.ahajournals.org/content/117/5/605
*  Predictors of Long-Term Healthy Arterial Aging | JACC: Cardiovascular Imaging
Our analysis demonstrates that participants with persistent CAC = 0 had an overall lower cardiovascular risk factor profile. The healthy arterial aging group had a significantly lower level for all of the individual cardiovascular risk factors and a higher level for all of the healthy lifestyle factors, except Mediterranean diet. The absence of traditional CVD risk factors was also associated with persistent CAC = 0 when compared with participants with ≥3 CVD risk factors. However, there was no single modifiable traditional cardiovascular risk factor whose absence was strongly associated with healthy arterial aging. This is similar to a large cross-sectional cohort study of almost 17,000 participants by Boutouyrie et al. (19) in which sex, dyslipidemia, and smoking were not significantly associated with arterial aging, which was classified as an increased ...
  http://imaging.onlinejacc.org/content/8/12/1393
*  Innovative Strategies For Risk Reduction Following CABG - Full Text View - ClinicalTrials.gov
Background: Treatment targets for cardiac risk factor reduction are not being met. Therefore, there is a need for new strategies to assist patients in meeting these goals.. Objective: To determine the amount of any additional benefit on risk factor reduction associated with the consumption of the 'dietary portfolio' (a low fat diet with soy, nuts and viscous fibres), above that achieved with medical management in diabetic patients following cardiac surgery.. Description: 35 cardiac surgery patients with diabetes will be instructed on how to incorporate the dietary portfolio foods into their diet for four weeks. Changes in blood cholesterol, markers of inflammation, blood sugar control and modifiable risk factors will be assessed after 2 and 4 weeks of therapy.. Relevance: Maximizing cardiac risk factor reduction through a combined approach (dietary plus medication) should improve outcomes, reduce rates of re-hospitalization ...
  https://clinicaltrials.gov/ct2/show/NCT00462436
*  Sabinet | Adherence to cardiovascular risk factor modification in patients with hypertension : cardiovascular topic
<I>Aim:</I> The effectiveness of the support of a healthcare practitioner and a family member in producing changes in cardiovascular risk factor modification was tested in a randomised, controlled trial in patients with hypertension. <br><I>Methods:</I> The primary outcome measured after the 24-week intervention was blood pressure change. Secondary outcomes included patients' adherence to the programme, their knowledge about hypertension, exercise capacity, body weight, self-reported ability to control stress, adherence to medication and salt restriction, as well as symptoms. <br><I>Results:</I> There were no marked improvements in blood pressure regulation in either group. The differences between the experimental and control groups were 3 mmHg (CI -6.18-12.18) for systolic blood pressure and 4 mmHg (CI -1.48-9.48) for diastolic blood pressure. The estimated ...
  http://journals.co.za/content/cardio/16/2/EJC23982
*  A randomized lifestyle intervention with 5-year follow-up in subjects with impaired glucose tolerance : pronounced short-term...
AIMS: To compare data on cardiovascular risk factor changes in lipids, insulin, proinsulin, fibrinolysis, leptin and C-reactive protein, and on diabetes incidence, in relation to changes in lifestyle.. METHODS: The study was a randomized lifestyle intervention trial conducted in northern Sweden between 1995 and 2000, in 168 individuals with impaired glucose tolerance (IGT) and body mass index above 27 at start. The intensive intervention group (n = 83) was subjected to a 1-month residential lifestyle programme. The usual care group (n = 85) participated in a health examination ending with a single counselling session. Follow-up was conducted at 1, 3 and 5 years.. RESULTS: At 1-year follow-up, an extensive cardio-metabolic risk factor reduction was demonstrated in the intensive intervention group, along with a 70% decrease of progress to type 2 diabetes. At 5-year follow-up, most of these beneficial effects had disappeared. Reported physical activity and fibre intake as well ...
  http://umu.diva-portal.org/smash/record.jsf?pid=diva2:224433
*  Estrogen, HDL, and Coronary Heart Disease in Women - Full Text View - ClinicalTrials.gov
BACKGROUND:. Coronary heart disease (CHD) is the leading cause of death and disability in postmenopausal women in the United States. Low plasma levels of high-density lipoprotein cholesterol (HDL-C) are a well-established risk factor for CHD. Elevated plasma triglyceride (TG) levels are also a risk factor for CHD in women. HDL particles are heterogeneous in composition (containing apo A-I only, LpAI, or apo A-I and apo A-II, LpAIAII) and charge and size (preBeta1, preBeta2, alpha1-3, preAlpha1-4). Different HDL subpopulations have different physiological functions and therefore may vary in their anti-atherogenic potential. Changes in alpha1 HDL subpopulations are a predictor of coronary disease progression in men. Hormonal replacement therapy (HRT) increases plasma levels of HDL-C, but has adverse effects on TG and C-reactive protein (CRP) levels. While observational studies had indicated a protective role of HRT in CHD, recent intervention studies have shown no CHD ...
  https://clinicaltrials.gov/ct2/show/NCT00083824
*  Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort...
Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort Study. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
  http://libros.duhnnae.com/2017/jun9/149861632719-Increased-Serum-Sodium-and-Serum-Osmolarity-Are-Independent-Risk-Factors-for-Developing-Chronic-Kidney-Disease-5-Year-Cohort-Study.php
*  Am I at Risk for Breast Cancer?
There is really no way to know for sure if you're going to get breast cancer, though certain risk factors can make it more likely. However, having one or more risk factors does not necessarily mean that you will get breast cancer. In fact, you can have all the risk factors and never get breast cancer, or you can have no known risk factors and still get the disease.. If you agree with any of the following bolded statements, you may be at an increased risk of developing breast cancer. Some risk factors are out of your control, such as your age or family history. Others, like drinking one or more alcoholic drinks a day or taking hormones, are factors you can control.. Each time you agree with a statement, ask yourself if you are doing all that you can to control that particular risk factor. It ...
  http://peopleshealth.staywellsolutionsonline.com/34,BBreRF1
*  Abstract 15476: Relation of Blood Pressure Indices with Differential Risk for Cardiovascular Events: The Atherosclerosis Risk...
BACKGROUND: Distinct components of blood pressure (BP) elevation include measures of pulsatile versus steady state load. The extent to which distinct BP components may be associated with varying risk for different cardiovascular outcomes remains uncertain.. METHODS: We studied 10,007 participants (mean age 54±6 years, 56% women, 21% African American) of the Atherosclerosis Risk in Communities Study who were free of cardiovascular disease at baseline. We used Cox proportional hazards models to compare the contributions of systolic (SBP), diastolic (DBP), pulse pressure (PP), and mean arterial pressure (MAP) to risk for coronary heart disease (CHD), heart failure (HF), stroke, and all-cause mortality. A larger -2 log-likelihood difference for a model with a single BP measure removed (compared to a full model with 2 measures being compared) was considered to reflect a greater contribution of that BP measure to risk for the given outcome.. ...
  http://circ.ahajournals.org/content/126/Suppl_21/A15476
*  Long-term impact of developing a postoperative pulmonary complication after lung surgery | Thorax
Results 86 of 670 patients (13%) who had undergone a lung resection developed a PPC. Those patients had a significantly longer hospital LOS in days (13, 95% CI 10.5-14.9 vs 6.3, 95% CI 5.9 to 6.7; p,0.001) and higher rates of ITU admissions (28% vs 1.9%; p,0.001) and 30-day hospital readmissions (20.7% vs 11.9%; p,0.05). Significant independent risk factors for development of PPCs were COPD and smoking (p,0.05), not age. Excluding early postoperative deaths, developing a PPC resulted in a significantly reduced overall survival in months (40, 95% CI 34 to 44 vs 46, 95% CI 44 to 47; p=0.006). Those who developed a PPC had a higher rate of non-cancer-related deaths (11% vs 5%; p=0.020). PPC is a significant independent risk factor for late deaths in non-small cell lung cancer patients (HR 2.0, 95% CI 1.9 to 3.2; p=0.006). ...
  http://thorax.bmj.com/content/71/2/171
*  Plus it
Purpose: Well-established risk factors for breast cancer include family history (FH), BRCA mutations and biopsies with atypical hyperplasia (AH) or lobular carcinoma in situ (LCIS). Several mathematical models, including the Gail and Tyrer-Cuzick models, have been developed to quantify a patient's risk for developing breast cancer. These models all differ in the list of variables and risk factors that are included in risk calculations. As a result, there is no single model that best estimates the risk for all high risk patients. The purpose of this study is to examine the application of the Gail and Tyrer-Cuzick models in a contemporary cohort of women who are enrolled in a comprehensive high-risk breast cancer database.. Methods: The institutional High Risk Breast Cancer Consortium (HRBCC) was established in January 2011. Patients who were ...
  http://cebp.aacrjournals.org/content/26/5_Supplement/A29
*  動脈硬化と関連医療との関連のご発表をご期待しております - メディカルテクニカへようこそ
Acute myocardial infarction (AMI) continues a worldwide cause of mortality [1]. In-hospital and 6-month-mortality are approximately 5-7% versus 12-13%, respectively [2, 3]. Estimated risk of mortality for AMI is based on the clinical status of the patients [4]. Recent studies showed that conventional risk factors are inadequate for predicting cardiovascular (CV) mortality and morbidity. A novel risk factor called arterial stiffness, which is a defined reduction of the compliance of arterial wall, and relationship between coronary heart disease (CHD) have been demonstrated. Arterial stiffness results in faster reflection of the forward pulse wave from bifurcation points in peripheral vessels. As a result of new waveform, systolic blood pressure (SBP) increases, diastolic blood pressure (DBP) decreases, cardiac workload increases, and coronary perfusion falls down. It plays a major role in the determination of cardiovascular outcomes, and it ...
  https://www.medicalteknika.jp/arterial-stiifness-24hrs-48hrs-72hrs/%E3%82%A2%E3%83%AB%E3%83%86%E3%83%AA%E3%82%AA%E3%82%B0%E3%83%A9%E3%83%95-%E5%8B%95%E8%84%88%E7%A1%AC%E5%8C%96%E8%A8%88/%E3%82%A2%E3%83%AB%E3%83%86%E3%83%AA%E3%82%AA%E3%82%B0%E3%83%A9%E3%83%95-%E5%8B%95%E8%84%88%E7%A1%AC%E5%8C%96/
*  Treatment of Coronary Atherosclerosis by Insulin Sensitizers in Insulin-Resistant Patients - Full Text View - ClinicalTrials.gov
Background: Type 2 diabetes and its antecedent, metabolic syndrome, are important risk factors for premature and accelerated atherosclerotic cardiovascular diseases. However, glycemic control by provision of endogenous or exogenous insulin induced only modest and not statistically significant reduction of the risk of myocardial infarction. We and other investigators have demonstrated that the use of insulin sensitizer, thiazolidinediones, resulted in favorable antiatherosclerotic effects in patients with type 2 diabetes or non-diabetic metabolic syndrome. It has become increasingly clear that morbidity and mortality associated with coronary artery disease (CAD) are often associated with lesions that are not obstructive but prone to rupture, the so-called vulnerable plaques. Conventional coronary angiography is not suitable for identifying vulnerable plaques. They may be detected by intravascular ultrasound (IVUS) and recently developed high-resolution ...
  https://clinicaltrials.gov/ct2/show/NCT00155350?recr=Open&cond=%22Atherosclerosis%22&rank=16