*  Plus it
Sections a-c, Anti-rhodopsin; sections d-f, anti-PDE6 antibody; sections g-i, anti-peripherin/rds antibody. Note that rhodopsin ... Sections of rKif3a+/− (a, c, e) and rKif3a−/− (b, d, f) retina were probed with anti-rhodopsin (a, b), anti-rod PDE6 (c, d), ... D, Confocal immunolocalization of KIF3A and rhodopsin in P14 littermate WT (a, d), rKif3a+/− (b, e), and rKif3a−/− (c, f) ... Trafficking of rhodopsin, PDE6 subunits, and peripherin/rds in P21 rKif3a−/− rods. Left column (a, d, g), rKif3a+/− retina ...
  http://www.jneurosci.org/content/29/45/14287
*  Lasers, Optics Enhance Optogenetics Studies | Features | Mar 2015 | EuroPhotonics
A.S. Chuong et al (2014). Noninvasive optical inhibition with a red-shifted microbial rhodopsin. Nat Neurosci, Vol. 17, pp. ...
  https://www.photonics.com/a57283/Lasers_Optics_Enhance_Optogenetics_Studies
*  Catching Proteins in the Act | Lightsources
The protein rhodopsin sees to it that our eyes can rapidly take in their ever-changing surroundings. Free-electron X-ray lasers ... rhodopsin, which sees to it that our eyes can rapidly take in their ever-changing surroundings.. Capturing ultrafast biological ... rhodopsin belongs.. At the free-electron laser facility LCLS at Stanford University in California, an international team under ...
  http://www.lightsources.org/press-release/2016/08/22/catching-proteins-act
*  IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin. - PubMed - NCBI
P23H rhodopsin protein degradation depends on lysosome function. (A) Wild-type or P23H rhodopsin was expressed in cells, and ... A) P23H rhodopsin is degraded by proteasome and lysosome. (B) IRE1[I642G] activation by 1NM-PP1 enhances P23H rhodopsin ... P23H rhodopsin protein degradation depends on proteasome function. (A) P23H rhodopsin was expressed in cells bearing IRE1[I642G ... Rhodopsin protein levels were detected by immunoblotting and quantified. (B) P23H rhodopsin was expressed in cells bearing IRE1 ...
  https://www.ncbi.nlm.nih.gov/pubmed/22219383
*  Public Outreach: Organization of SPP 1926
2007). Subsequently, rhodopsin-based optogenetic tools have been widely used. In recent years, many other optogenetic tools and ... 2007). The most successful and widely used optogenetic tools, i.e. the microbial rhodopsins, have their origins in Germany. In ... Optogenetic tools do not only address membrane currents and membrane potential, like the rhodopsins, or modifed ion channels in ...
  http://spp1926.cgi-host4.rz.uni-frankfurt.de/public-outreach/
*  Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors | JCB
Rhodopsin (Rho), rod-transducin (Gnat1), and rod cyclic nucleotide-gated channel α subunit (Cnga1) were highly expressed in the ... Rod PRs lacking Rds fail to form OS structures and possess rhodopsin solely in the tip of the cilium and IS membrane, causing ... The WT retina was labeled by rhodopsin (green) and S-opsin (red), demonstrating the presence of both rods and cones, ... The electroretinogram of the rhodopsin knockout mouse. Vis. Neurosci. 16:391-398. ...
  http://jcb.rupress.org/content/173/1/59
*  Genable Receives $6.8 Million Investment to Develop Gene Therapy for Dominant RP | blindness.org
Defects in rhodopsin are the most common cause of adRP, accounting for about 25 percent of all adRP cases.. "The rhodopsin gene ... Known as GT038, Genable's gene therapy is for people with adRP caused by mutations in the gene rhodopsin. The treatment works ...
  http://www.blindness.org/foundation-news/genable-receives-68-million-investment-develop-gene-therapy-dominant-rp
*  Table of Contents - August 04, 2000, 289 (5480) | Science
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor. By Krzysztof Palczewski, Takashi Kumasaka, Tetsuya Hori, Craig A ... COVER The three-dimensional x-ray crystal structure of the light-sensitive protein rhodopsin, at 2.8 Å. Members of this family ...
  http://science.sciencemag.org/content/289/5480
*  Plus it
I. Rhodopsin as the Primer. The use of rhodopsin as a primer for agonist-specific states is pertinent for the growing list of ... Lessons from Rhodopsin. A. Structural Basis for Mechanism of Activation in a G-Protein-Coupled Receptor, Mammalian Rhodopsin. ... Rhodopsin structure and function. A, ribbon drawings of rhodopsin. Helices I-VIII are colored as a spectrum of visible light ... G. Lessons from Gain of Function Rhodopsin Mutations. A complete discussion of activating mutations of rhodopsin is available ( ...
  http://pharmrev.aspetjournals.org/content/57/2/147
*  WNT Signaling | www.antibodies-online.com
RHO - Rhodopsin: RHO antibodies RHO ELISA Kits RHO Proteins ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1): ...
  https://www.antibodies-online.com/wnt-signaling-pathway-10/
*  Johannes Schöneberg
... rhodopsin arranged in tracks but no R-G-pre-complexes (middle, black trace), rhodopsin arranged in tracks with R-G-pre- ... M Gunkel*, J Schöneberg*, W Alkhaldi, S Irsen, F Noé, U B Kaupp, A Al-Amoudi, (2015) Higher-order architecture of rhodopsin in ... Note the highly crowded environment due to the high rhodopsin density. See our work in the Biophysical Journal 2014: Explicit ... Activated rhodopsins can now in turn activate G-proteins (blue) triggering the downstream reactions of the photo-activation ...
  https://sites.google.com/a/schoeneberglab.org/johannes-schoeneberg/
*  Rhodopsinn
Rhodopsin is the protein found in retinas that converts light into a molecular signal that is eventually transmitted to the ... We have recently solved the three-dimensional structure of rhodopsin (Science, 289, 739-745 (2000)). Much work remains to ... and to determine how the structure of the surrounding protein affects the absorption properties of the chromophore in rhodopsin ...
  http://faculty.washington.edu/stenkamp/rhodopsin.html
*  9- Duplex Retina Flashcards by Andrea Sandifer | Brainscape
When a rhodopsin molecule is in the bleached state can it capture another quatua? ... Rods do not become more sensitive then cones until what percentage of rhodopsin is regenerated ... Fewer than 20% of the quanta incident on the retina are absorbed by rhodopsin ... How many quanta of light are needed to bleach a molecule of rhodopsin ...
  https://www.brainscape.com/flashcards/9-duplex-retina-6147499/packs/9437652
*  Light & Vision - Martin Flashcards by Christina Roullard | Brainscape
Rhodopsin - Converts cis to trans-retinal leading to action potential in ganglion cell. - Post transduction: Na+ channel can't ...
  https://www.brainscape.com/flashcards/light-amp-vision-martin-2206978/packs/3912954
*  Special Sense Organs Flashcards by User Unknown | Brainscape
Rhodopsins belong to the G-protein-coupled receptor family and are extremely sensitive to light, enabling vision in low-light ... during dark adaptation (dark vision) rhodopsin is synthesized in the rods. Severe vitamin A deficiency over many months causes ...
  https://www.brainscape.com/flashcards/special-sense-organs-2399014/packs/4178995
*  Test 2 Week 1 Flashcards by Stephen Barna | Brainscape
3) Rhodopsin. 4) Transducin. 5) Na/Ca exchanger. 6) Rhodopsin Kinase. 7) Phosphodiesterase 8) cGMP-gated Na channel 9) b- ... The rhodopsin molecule has a ___TM domain and is linked to ___ in opsin by a ___-base linkage and when protonated the maximum ... So the pathway for light is it comes into the rod cell and hits rhodopsin, (which is comprised of opsin and 11-cis retinal ... For the retinoid cycle, once the all-trans-retinAl gets displaced from the rhodopsin molecule for recovery to take place, it ...
  https://www.brainscape.com/flashcards/test-2-week-1-5018113/packs/7368607
*  De novo characterization of the gene-rich transcriptomes of two color-polymorphic spiders, Theridion grallator and T....
Rhodopsin/carotenoid. Although not structurally related, we group rhodopsin and the carotenoid pigments together here simply ... Occurrence of " Drosophila " heme, melanin and rhodopsin pigment-pathway-associated genes in T. californicum and T. grallator ... O = Ommochrome, P = Pteridine, M = Melanin, H = Heme, R = Rhodopsin/Carotenoid. For full gene names see Tables 3 and 4. ... Wang T, Montell C: Rhodopsin formation in Drosophila is dependent on the PINTA retonoid-binding protein. J Neurosci. 2005, 25: ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-14-862
*  Yuri Ovchinnikov (biochemist) - Wikipedia
He contributed to the field of biophysics and biochemistry through his extensive research in rhodopsin and structural biology ... "Octopus rhodopsin. Amino acid sequence deduced from cDNA". FEBS Letters. 232 (1): 69-72. ISSN 0014-5793. PMID 3366250. ...
  https://en.wikipedia.org/wiki/Yuri_Ovchinnikov_(biochemist)
*  Stenkamp, Ronald | Department of Biological Structure
Rhodopsin. This G protein-coupled receptor is the photo-active molecule in the visual system. In response to light, it ... We are also pursuing studies of rhodopsin in complex with its protein ligands. This work is being done in collaboration with ...
  https://depts.washington.edu/biostr/user/427
*  Search | eLife
Rhodopsin targeted transcriptional silencing by DNA-binding Salvatore Botta et al. Photoreceptor genomic binding of a 20 base- ... pair-long DNA sequence by a synthetic DNA-binding protein turns off Rhodopsin expression. ...
  https://elifesciences.org/search?for=gene%20therapy