Timeline for Protein Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF from b.55.1.1: Pleckstrin-homology domain (PH domain ... Lineage for Protein: Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF. *Root: SCOPe 2.08 *. Class b: All beta proteins [ ... Protein Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF from b.55.1.1: Pleckstrin-homology domain (PH domain) appears in ... Protein Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF from b.55.1.1: Pleckstrin-homology domain (PH domain) first ...
Phenotype data for mouse gene Arhgef38. Discover Arhgef38s significant phenotypes, expression, images, histopathology and more. Data for gene Arhgef38 is all freely available for download.
ALSIN RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR ALS2; ALS2. Gene and Variant Databases. *NCBI Gene ... Two of the mutations that cause this disorder delete nucleotides, and one mutation replaces one nucleotide with an incorrect ... nucleotide. These mutations alter the instructions for producing alsin. As a result, alsin is unstable and is broken down ...
Rho guanine nucleotide exchange factor (GEF) 35 is a protein in humans that is encoded by the ARHGEF35 gene. ENSG00000288422 ... "Entrez Gene: Rho guanine nucleotide exchange factor (GEF) 35". Retrieved 2013-02-17. v t e (Articles with short description, ...
rho GTP-Binding Proteins. *ral Guanine Nucleotide Exchange Factor. *Tumor Suppressor Gene ... Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases ( ... RalGPS2 is a Ras-independent Guanine Nucleotide Exchange Factor (GEF) for RalA containing a PH domain and an SH3-binding region ... Although the Rgr proto-oncogene belongs to the RalGDS family of guanine nucleotide exchange factors (GEFs), we show that upon ...
Heo J, Thapar R, Campbell SL . Recognition and activation of Rho GTPases by Vav1 and Vav2 guanine nucleotide exchange factors. ... Barrio-Real L, Kazanietz MG . Rho GEFs and cancer: linking gene expression and metastatic dissemination. Sci Signal 2012; 5: ... Liu BP, Burridge K . Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins. Mol ... Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B. Proc Natl ...
Rho GTPase associated proteins. Rho guanine nucleotide exchange factors (GEFs). 16800 (Arhgef2). ... RefSeq) Rho/Rac guanine nucleotide exchange factor 2. KO. K12791 Rho guanine nucleotide exchange factor 2. ...
ARHGEF12; Rho guanine nucleotide exchange factor 12 [KO:K07532]. 387 RHOA; ras homolog family member A [KO:K04513]. ... RFXAP; regulatory factor X associated protein [KO:K08063]. 4800 NFYA; nuclear transcription factor Y subunit alpha [KO:K08064] ... NFYB; nuclear transcription factor Y subunit beta [KO:K08065]. 4802 NFYC; nuclear transcription factor Y subunit gamma [KO: ... TGFB3; transforming growth factor beta 3 [KO:K13377]. 1594 CYP27B1; cytochrome P450 family 27 subfamily B member 1 [KO:K07438 ...
Name: alsin Rho guanine nucleotide exchange factor. Synonyms: 3222402C23Rik, Als2cr6, 9430073A21Rik, Alsin ...
Rho guanine nucleotide exchange factor 37. 1.0000. 21. PHOSPHO1. Phosphoethanolamine/phosphocholine phosphatase 1. 1.0000. 21. ...
Name: Rho guanine nucleotide exchange factor 3. Synonyms: 1200004I24Rik, C76747, 9830169H03Rik. Type: Gene ... Name: transcription factor 4. Synonyms: SEF-2, ITF-2, MITF-2B, MITF-2A, ME2, E2.2, TFE, E2-2, SEF2-1, ASP-I2, ITF-2b, ...
2004) GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation. J Biol ... 1999) Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is ... a common and essential factor is a postsynaptic [Ca2+]i elevation (Hartell, 2002; Safo et al., 2006). Indeed, some upstream ( ...
Rho guanine nucleotide exchange factor 7 (ARHGEF7) Proteins. Rho guanine nucleotide exchange factor 7 S homeolog (arhgef7.S) ... Rho guanine nucleotide exchange factor 7 (Arhgef7) Proteins. Rho guanine nucleotide exchange factor (GEF7) (Arhgef7) Proteins. ... rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7)). Rho GTPases play a fundamental role in numerous cellular processes ... Rho guanine nucleotide exchange factor (GEF) 7b (arhgef7b) Proteins. ARHGEF7 Proteins. arhgef7 Proteins. bbh Proteins. BETA-PIX ...
SOS Ras/Rho guanine nucleotide exchange factor 2 Synonyms:. ( Nomenclature history ) Gene Function:. Ras1 guanine nucleotide ...
Rho GTPase associated proteins. Rho guanine nucleotide exchange factors (GEFs). 9181 (ARHGEF2). ... RefSeq) Rho/Rac guanine nucleotide exchange factor 2. KO. K12791 Rho guanine nucleotide exchange factor 2. ...
Stendel, C. et al. Peripheral Nerve Demyelination Caused by a Mutant Rho GTPase Guanine Nucleotide Exchange Factor, Frabin/FGD4 ... Nakhro, K. et al. SET binding factor 1 (SBF1) mutation causes Charcot-Marie-Tooth disease type 4B3. Neurology (2013). doi: ... Hirano, R. et al. SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma. Neurology (2004). doi:10.1212 ... Kim, H.-J. et al. Mutations in PRPS1, Which Encodes the Phosphoribosyl Pyrophosphate Synthetase Enzyme Critical for Nucleotide ...
The guanine nucleotide exchange factor (GEF) Dbl targets Rho family proteins thereby stimulating their GDP/GTP exchange, and ... Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that PH ... These putative guanine nucleotide exchange factors for Rho family small GTP-binding proteins (G proteins) all contain a Dbl ... is catalysed by guanine nucleotide exchange factors (GEFs) in the Dbl family. The proteins encoded by members of the Dbl family ...
The activation of RhoA is regulated by a guanine nucleotide exchange factor (Rho-GEF). This protein is found in the cortex ... Rho-GEF exchanges the GDP bound to RhoA with GTP. The binding of GTP activates RhoA, which in turn triggers the formation of ... Animal cell cytokinesis: the rho-dependent actomyosin-anilloseptin contractile ring as a membrane microdomain gathering, ...
Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 ... ARHGEF11 (untagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2. * * 10 ug. 10 ug ... ARHGEF11 (tGFP-tagged) - Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2. * * 10 ug. 10 ... Lenti-ORF clone of ARHGEF11 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript ...
The guanine nucleotide exchange factor (GEF) Dbl targets Rho family proteins thereby stimulating their GDP/GTP exchange, and ... Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that PH ... These putative guanine nucleotide exchange factors for Rho family small GTP-binding proteins (G proteins) all contain a Dbl ... is catalysed by guanine nucleotide exchange factors (GEFs) in the Dbl family. The proteins encoded by members of the Dbl family ...
The guanine nucleotide exchange factor (GEF) Dbl targets Rho family proteins thereby stimulating their GDP/GTP exchange, and ... Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that PH ... These putative guanine nucleotide exchange factors for Rho family small GTP-binding proteins (G proteins) all contain a Dbl ... is catalysed by guanine nucleotide exchange factors (GEFs) in the Dbl family. The proteins encoded by members of the Dbl family ...
DyNamin Binding Protein (DNMBP), also called Tuba, is a Cdc42-specific Guanine nucleotide Exchange Factor (GEF) that binds ... It serves as a link between dynamin function, Rho GTPase signaling, and actin dynamics. It plays an important role in ...
The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J ... Yamashita T, Tohyama M (2003) The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 6: ... Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273: 245-248. ... Neurotrophins (NTs), including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), NT-3, and NT-4/5, regulate ...
The Rho guanine nucleotide exchange factor (RhoGEF) Trio promotes actin polymerization by directly activating the small GTPase ... Single tryptophan mutants of FtsZ: nucleotide binding/exchange and conformational transitions.. Biochim Biophys Acta. 2014; ... We observed dynamic exchange of the ataxin-1 protein into these NBs; notably, cell exposure to a pro-oxidant stress could ... Some of those factors include, but are not limited to, interactions with mobile and immobile targets or obstacles. Besides ...
Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix. Neuron. ... The argos gene encodes a diffusible factor that regulates cell fate decisions in the Drosophila eye. Cell. 69: 963-75. PMID ... A novel Dbl family RhoGEF promotes Rho-dependent axon attraction to the central nervous system midline in Drosophila and ... Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho. Current ...
Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF. The ... which binds two guanine nucleotide exchange factors (GEFs) for Rho and is mediated by the activation of Rho-initiated (Ras ... Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors. Biochemical and biophysical ... The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG. ...
DOCK8 belongs to the DOCK180 superfamily of proteins which have a role in guanine nucleotide exchange for Rho family GTPases. ... DOCK180- related guanine nucleotide exchange factors are shown to have roles in actin cytoskeletal rearrangement, cell ... macrophage-colony stimulating factor (M-CSF), granulocyte-colony stimulating factor (G-CSF), leptin, and growth hormone. [17] ... ciliary neurotropic factor, oncostatin M, leukemia inhibitory factor), IFNs, and the IL-10 family (IL-10, IL-19, IL-20, IL-22, ...
Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix ... Cdc42 is activated by recruitment of the Cdc42/Rac guanine-nucleotide exchange factor (GEF) βPIX to the LE by Scrib, which ... Participation of small GTPases in dorsal closure of the Drosophila embryo: distinct roles for Rho subfamily proteins in ... The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis ...
... including a novel association with the SOS Ras/Rho guanine nucleotide exchange factor 2 gene, SOS2 (P=5.4×10-8 by sequence ... we identified single nucleotide polymorphisms at seven new loci associated with eGFRcrea (PPM1J, EDEM3, ACP1, SPEG, EYA4, ...