Retinoblastoma protein - Wikipedia
The retinoblastoma protein (protein name abbreviated Rb; gene name abbreviated Rb, RB or RB1) is a tumor suppressor protein ... "The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein". ... GeneReviews/NIH/NCBI/UW entry on Retinoblastoma Retinoblastoma Genetics Drosophila Retinoblastoma-family protein - The ... Welch PJ, Wang JY (November 1993). "A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl ...
Purified Mouse Anti-Human Retinoblastoma Protein
"RB1 deletion in retinoblastoma protein pathway-disrupted cells results in DNA damage and cancer progression" by Aren E....
Proliferative control in cancer cells is frequently disrupted by mutations in the retinoblastoma protein (RB) pathway. ... Aren E. Marshall, Michael V. Roes, Daniel T. Passos, Megan C. DeWeerd, et al.. "RB1 deletion in retinoblastoma protein pathway- ... RB1 deletion in retinoblastoma protein pathway-disrupted cells results in DNA damage and cancer progression ... Proliferative control in cancer cells is frequently disrupted by mutations in the retinoblastoma protein (RB) pathway. ...
Addgene: Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties.
Retinoblastoma protein (pSer612) antibody
Retinoblastoma-Like Protein p107 (definition)
Like Protein; Retinoblastoma Like Protein 1; p107 Tumor Suppressor Protein; Retinoblastoma Like Protein p107; RBL1 Protein; ... RBL1 protein, human 0 *Retinoblastoma-Like Protein p107. Rbl1 protein, mouse 0 *Retinoblastoma-Like Protein p107. To share this ... ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS. Other names p107, Retinoblastoma- ...
Retinoblastoma: Background, Pathophysiology, Epidemiology
The most widely held concept of histogenesis of retinoblastoma holds that it generally arises from a multipotential precursor ... Mittnacht S. The retinoblastoma protein--from bench to bedside. Eur J Cell Biol. 2005 Mar. 84(2-3):97-107. [QxMD MEDLINE Link] ... Functions of the retinoblastoma protein. Bioessays. 1999 Nov. 21(11):950-8. [QxMD MEDLINE Link]. ... DiCiommo D, Gallie BL, Bremner R. Retinoblastoma: the disease, gene and protein provide critical leads to understand cancer. ...
Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins | Oncotarget
The retinoblastoma family of pocket proteins (composed by pRb, p107 and p130) is a family of negative regulators of the cell ... The members of the retinoblastoma family of pocket proteins, pRb, p107 and p130, are negative regulators of the cell cycle with ... Medema RH, Herrera RE, Lam F and Weinberg RA., Growth suppression by p16ink4 requires functional retinoblastoma protein. ... Protein and RNA expression analysis. For protein expression analysis, cell extracts were prepared using RIPA buffer (150mM NaCl ...
polyclonal spep - Retinoblastoma protein
... are proteins in bacon proteins in eggs proteins in photosystem 2 proteins of a cell proteins on keto proteins per day proteins ... are proteins in bacon proteins in eggs proteins in photosystem 2 proteins of a cell proteins on keto proteins per day proteins ... of proteins are polymers of proteins easy to digest proteins enzyme proteins examples proteins for lunch proteins form protein ... of proteins are polymers of proteins easy to digest proteins enzyme proteins examples proteins for lunch proteins form protein ...
retinoblastoma protein
... retinoblastoma pdf, retinoblastoma prognosis, retinoblastoma protein, retinoblastoma radiology, retinoblastoma signs, ... retinoblastoma staging, retinoblastoma symptoms, retinoblastoma tem cura, retinoblastoma treatment, znrd1 hiv, znrd1 protein, ... retinoblastoma genereviews, retinoblastoma genetics, retinoblastoma gpc, retinoblastoma icd 10, retinoblastoma in children, ... retinoblastoma adalah, retinoblastoma bilateral, retinoblastoma cancer, retinoblastoma definition, retinoblastoma eye, ...
antibody test nyc - Retinoblastoma protein
... are proteins in bacon proteins in eggs proteins in photosystem 2 proteins of a cell proteins on keto proteins per day proteins ... are proteins in bacon proteins in eggs proteins in photosystem 2 proteins of a cell proteins on keto proteins per day proteins ... of proteins are polymers of proteins easy to digest proteins enzyme proteins examples proteins for lunch proteins form protein ... of proteins are polymers of proteins easy to digest proteins enzyme proteins examples proteins for lunch proteins form protein ...
p38γ is essential for cell cycle progression and liver tumorigenesis | Nature
... γ induces proliferation after partial hepatectomy by promoting the phosphorylation of retinoblastoma tumour suppressor protein ... cyclin protein complex1. However, control of the G0-to-G1 transition is not completely understood. Here we demonstrate that p38 ... Canhoto, A. J., Chestukhin, A., Litovchick, L. & DeCaprio, J. A. Phosphorylation of the retinoblastoma-related protein p130 in ... Lundberg, A. S. & Weinberg, R. A. Functional inactivation of the retinoblastoma protein requires sequential modification by at ...
An "in vitro"study on lung cells exposed to fluoro-edenite fibres. Biological role of retinoblastoma proteins
Biological role of retinoblastoma proteins. MUSUMECI, GIUSEPPE. Primo. ;CARDILE, Venera;M. L. CARNAZZA;G. MARTINEZ;LORETO, ... Introduction: In this study we addressed the expression of Rb and pRb protein in human lung epithelial A549 and MeT-5A cell ... Introduction: In this study we addressed the expression of Rb and pRb protein in human lung epithelial A549 and MeT-5A cell ... Rb and pRb protein; human lung epithelial A549; MeT-5A cell cultures treated with three ...
Activation of a retinoblastoma-protein-dependent pathway by sphingosine. | Palmetto Profiles
Serval - Neuron-associated class III beta-tubulin isotype, microtubule-associated protein 2, and synaptophysin in human...
... and synaptophysin epitopes in poorly differentiated and maturing neoplastic phenotypes in retinoblastomas attests to the ... microtubule-associated protein 2 (MAP2), and synaptophysin. Anti-h beta 4 and anti-MAP2 immunostaining was consistently ... h beta 4 and MAP2 epitopes by poorly differentiated neoplastic cells may indicate early neuronal commitment in retinoblastoma. ... We studied by immunohistochemistry 26 retinoblastomas in situ using monoclonal antibodies specific for the neuron-associated ...
Weis2014 - Data driven Mammalian Cell Cycle Model | BioModels
Retinoblastoma-associated protein 0.1071 mmol. actCycACdk1. Cyclin-A2 ; Cyclin-dependent kinase 1 0.003801725709734 mmol. ... It reproduces protein time courses in wild-type cells, mimics correctly the phenotypes of many mutant strains, and predicts the ... Since many of the proteins involved in regulating the cell cycle of C. crescentus are conserved among many genera of a- ... The mechanism, which is based on the synthesis and degradation of three master regulator proteins (CtrA, GcrA, and DnaA), ...
IJMS | Free Full-Text | Cigarette Smoking Promotes Infection of Cervical Cells by High-Risk Human Papillomaviruses, but not...
Women were tested for hrHPV DNA, using Multiplex Genotyping (MPG), and E7 protein, using a novel sandwich ELISA method, and ... Smoking is not related to an increased probability of E7 protein positivity for hrHPV positive women. ... which examined the role of E7 protein detection in cervical cancer screening. ... Retinoblastoma protein) [20,21], respectively. The current analysis, apart from examining the role of smoking on the ...
BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses...
Additionally, the mRNA and protein expression of cyclin D1, cyclin-dependent kinase 4 (CDK4) and retinoblastoma protein (pRb), ... and the underlying mechanism involving in cell-cycle regulatory proteins were analyzed. The proliferative ability of MCF-7 ...
4X8N: Crystal structure of Ash2L SPRY domain in complex with phosphorylated RbBP5
Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: an immunohistochemical study
We examined the expression of p16 and Rb protein by means of immunohistochemistry in 61 non-small cell lung cancers and have ... Cdk4-mediated phosphorylation of Rb protein is inhibited by p16, a product of a possible tumor suppressor gene. ... Retinoblastoma Protein / analysis* Substances * Carrier Proteins * Cyclin-Dependent Kinase Inhibitor p16 * Retinoblastoma ... Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: an immunohistochemical study Int J Cancer ...
Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial...
Characterization of protein kinase C beta isoforms action on retinoblastoma protein phosphorylation, vascular endothelial ... Characterization of protein kinase C beta isoforms action on retinoblastoma protein phosp ... Association of PKC beta 2 isoform with retinoblastoma protein was discovered in retinal endothelial cells, and PKC beta 2 ... Activation of protein kinase C (PKC) enhances the angiogenic process and is involved in the signaling of vascular endothelial ...
CDD Conserved Protein Domain Family: RB B
Conserved Protein Domain Family RB_B, The crystal structure of the Rb pocket bound to a nine-residue E7 peptide containing the ... LxCxE motif, shared by other Rb-binding viral and cellular proteins, shows that the LxCxE peptide binds a highly conserved ... Retinoblastoma-associated protein B domain. The crystal structure of the Rb pocket bound to a nine-residue E7 peptide ... containing the LxCxE motif, shared by other Rb-binding viral and cellular proteins, shows that the LxCxE peptide binds a highly ...
Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates...
v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket...
Cyclin A expression is repressed in quiescent cells by E2F acting in conjunction with its pocket protein partners Rb, p107, and ... Thus, v-Jun overrides the mitogen dependence of S-phase entry by deregulating Rb phosphorylation, E2F-pocket protein ... In particular, hormonal activation of a conditional v-Jun-estrogen receptor fusion protein in quiescent, growth factor-deprived ... Oncogene Protein p65(gag-jun), Oncogene Proteins, Phosphorylation, Plasmids, Protein-Serine-Threonine Kinases, Retinoblastoma ...
Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the...
Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the ... Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the ... Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the ... Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the ...
Frontiers | The Influence of miRNAs on Radiotherapy Treatment in Prostate Cancer - A Systematic Review
Heat shock protein 27; M, Mitosis; PTEN, Phosphatase and TENsin homolog; Rb, Retinoblastoma protein; RXRA, Retinoid X receptor ... This miRNA is related with prostate transmembrane protein, androgen-induced l(PMEPA1), and tumor protein p53 inducible nuclear ... described that miRNA-145 mimics can silence and deregulate the Speckle-type pox virus and zinc finger protein (POZ) protein ( ... protein kinase C epsilon (PKCϵ) and ZEB1 expression, proteins involved in EMT (40). In the same context, miRNA-30a has been ...
Mitotic progression following DNA damage enables pattern recognition within micronuclei | Nature
JCI - Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 1998. 391:597-601. View this article via: ... Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 1998. 391:601-605. View this article ... It has been reported that RA and arsenic trioxide (As2O3), can induce the degradation of the PML-RARα fusion protein (44, 45). ... Staining for the PML protein was carried out as described previously (22, 25). A Texas red-conjugated IgG was used as secondary ...
PRB2 | Cancer Genetics Web
The retinoblastoma family of proteins (pRb), which includes pRb/p105, p107 and pRb2/p130, acts as one of the most important ... We have previously reported that pRb2/p130, retinoblastoma related protein, could be involved in the silencing of ER-alpha gene ... It appears more and more clear that retinoblastoma (RB) family of proteins represents key molecules in tumour suppression. This ... We will focus on recent demonstrations regarding the involvement of the retinoblastoma family proteins (phosphorylated ...
Abhinav Adhikari, Ph.D. | Harvard Catalyst Profiles | Harvard Catalyst
Retinoblastoma Binding Proteins. 1. 2019. 95. 0.170. Why? Chromatin Immunoprecipitation. 1. 2021. 900. 0.160. Why? ...