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*  Tetrandrine protects mouse retinal ganglion cells from ischemic injury | DDDT
... on murine ischemia-injured retinal ganglion cells (RGCs). For this, we used serum deprivation cell model, glutamate and ... We also investigated cell survival of purified primary-cultured RGCs treated with Tet. An in vivo retinal ischemia/reperfusion ... After 48 hours, Tet protected staurosporine-induced RGC-5 cells from serum deprivation-induced cell death and significantly ... Tet administration (10 µM, 2 µL) 1 day before retinal ischemia showed RGC layer loss (greater survival), which was less than ...
  https://www.dovepress.com/tetrandrine-protects-mouse-retinal-ganglion-cells-from-ischemic-injury-peer-reviewed-article-DDDT
*  Impediments to Eye Transplantation: Ocular Viability Following Optic Nerve Transection or Enucleation | British Journal of...
Following enucleation (and reperfusion), outer retinal function is maintained from four to nine hours. Retinal ganglion cell ( ...
  http://bjo.bmj.com/content/early/2009/03/17/bjo.2008.155267
*  Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
... or with specific deletion of Atg5 in retinal ganglion cells, using the Atg5flox/flox mice reduces cell survival after ONT, ... Retinal ganglion cells (RGCs) are the sole projecting neurons of the retina and their axons form the optic nerve. Here, we show ... It induces retinal ganglion cell death, a process also occurring in glaucoma and other optic neuropathies. We analyzed ... Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice. Natalia Rodríguez-Muela, Francisco ...
  http://www.sebbm.es/web/en/science-for-society/article-of-the-month/689-autophagy-promotes-survival-of-retinal-ganglion-cells-after-optic-nerve-axotomy-in-mice
*  Intermediate filaments of zebrafish retinal and optic nerve astrocytes and Müller glia: differential distribution of...
... in the bundled retinal ganglion cell (RGC) axon layer, and in scattered cells of the inner plexiform layer (Figure 2C, D; ... recognition molecules by retinal ganglion cells and by optic pathway glia accompanies the successful regeneration of retinal ... Cytokeratin labeling of astrocytes was observed throughout the optic nerve and less intensely in cells in the retinal inner ... Within Müller cells, GFP fluorescence filled the entire cell while GFAP labelling was more restricted in distribution. No GFAP ...
  https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-3-50
*  Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity - Zurich Open...
DeParis, S W; Caprara, C; Grimm, C (2012). Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D- ... Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity ...
  http://www.zora.uzh.ch/id/eprint/68389/
*  The autoregulation of retinal ganglion cell number | Development
Interestingly, the application of exogenous NGF reversed the effects of ganglion cell ablation on ganglion cell death. Because ... both by inhibiting the generation of new ganglion cells and by killing incoming migratory ganglion cells. Selective ... We show that in the chick embryo, stratified retinal ganglion cells (RGCs) are themselves responsible for providing the signals ... which eventually led to the repopulation of the ganglion cell layer and a large decrease in the physiological cell death ...
  http://dev.biologists.org/content/128/1/117
*  Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model | IOVS | ARVO...
Purpose : Recent studies in sigma-1 receptors (σ-1r)- deficient mice demonstrated increased losses of retinal ganglion cells ( ... Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model ... Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model ... Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model. Invest. ...
  http://iovs.arvojournals.org/article.aspx?articleid=2559117
*  Alkaline Phosphatase Enriched Exosomes as Guidance Cues in the Developing Avian Optic Chiasm | IOVS | ARVO Journals
... have been associated with guiding the contralateral and ipsilateral navigation of developing axons of retinal ganglion cells ( ... Exosomes are densely packed signaling particles released by cells.. Methods : Chick embryos were incubated at 38.5°C. 15μ ...
  http://iovs.arvojournals.org/article.aspx?articleid=2557521
*  Determining the contribution of specific retinal circuits to mouse retinal ganglion cell space-time tuning | IOVS | ARVO...
Determining the contribution of specific retinal circuits to mouse retinal ganglion cell space-time tuning ... Determining the contribution of specific retinal circuits to mouse retinal ganglion cell space-time tuning ... Determining the contribution of specific retinal circuits to mouse retinal ganglion cell space-time tuning. Invest. Ophthalmol ... Purpose : Previously we demonstrated that the mouse retinal ganglion cell (GC) space-time receptive field can be separated into ...
  http://iovs.arvojournals.org/article.aspx?articleid=2561793
*  Retinal ganglion cell - Wikipedia
The six types of retinal neurons are bipolar cells, ganglion cells, horizontal cells, retina amacrine cells, and rod and cone ... Retinal ganglion cells spontaneously fire action potentials at a base rate while at rest. Excitation of retinal ganglion cells ... there are at least five main classes of retinal ganglion cells: Midget cell (Parvocellular, or P pathway; P cells) Parasol cell ... A retinal ganglion cell (RGC) is a type of neuron located near the inner surface (the ganglion cell layer) of the retina of the ...
  https://en.wikipedia.org/wiki/Retinal_ganglion_cell
*  Intrinsically photosensitive retinal ganglion cells - Wikipedia
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or ... Recent research has shown that these retinal ganglion cells, unlike other retinal ganglion cells, are intrinsically ... a new role was found for the photoreceptive ganglion cell. Zaidi and colleagues showed that in humans the retinal ganglion cell ... "Parallel inhibition of dopamine amacrine cells and intrinsically photosensitive retinal ganglion cells in a non-image-forming ...
  https://en.m.wikipedia.org/wiki/Photosensitive_ganglion_cell
*  Extracellular Recordings from Human Retinal Ganglion Cells | Science
Extracellular Recordings from Human Retinal Ganglion Cells Message Subject. (Your Name) has forwarded a page to you from ... Ganglion cells were studied in the isolated retina, with extracellular recordings. Activity was found similar to that seen in ...
  http://science.sciencemag.org/content/171/3975/1021
*  Retinal ganglion cells - Biology-Online Dictionary
retinal ganglion cells cells of the innermost nuclear layer of the retina, the ganglion cell layer, which project axons through ... Retrieved from "https://www.biology-online.org/dictionary/index.php?title=Retinal_ganglion_cells&oldid=61765" ...
  https://www.biology-online.org/dictionary/Retinal_ganglion_cells
*  Imaging Technique Visualizes Individual Retinal Ganglion Cells | BioScan | Apr 2017 | BioPhotonics
Imaging Technique Visualizes Individual Retinal Ganglion Cells. BioPhotonics. Apr 2017 A new imaging technique that modifies ... Through experimentation, the researchers were able to distinguish individual retinal ganglion cells (RGCs), which bear most of ... While RGCs were the main focus of the investigations, they are just one type of cell that can be imaged using this new ... "Not only RGCs, but potentially other translucent cell classes and cellular structures." More studies will be needed to improve ...
  https://www.photonics.com/a61523/Imaging_Technique_Visualizes_Individual_Retinal
*  Rabbit retinal ganglion cells express functional alpha7 nicotinic acetylcholine receptors. - PubMed - NCBI
Am J Physiol Cell Physiol. 2005 Sep;289(3):C644-55. Epub 2005 May 4. Research Support, N.I.H., Extramural; Research Support, U. ... Rabbit retinal ganglion cells express functional alpha7 nicotinic acetylcholine receptors.. Strang CE1, Andison ME, Amthor FR, ... It is well known that cholinergic agents affect ganglion cell (GC) firing rates and light responses in the retinas of many ... Am J Physiol Cell Physiol. 2005 Sep;289(3):C644-55. Epub 2005 May 4. ...
  https://www.ncbi.nlm.nih.gov/pubmed/15872006
*  Processing of Natural Temporal Stimuli by Macaque Retinal Ganglion Cells | Journal of Neuroscience
Models for retinal ganglion cells.A, Model for the MC cells.I i is the retinal illuminance; LP1 is a low-pass filter consisting ... Models of retinal ganglion cells. We first developed models for all ganglion cell types from which we recorded. The model for ... Below 2-3 Hz, PC cell signals contained more power than those of MC cells. Response variation between individual ganglion cells ... M off-center PC cell, Gon for the +M-L on-center PC cell, Goff for the −M+L off-center PC cell, and Bon for the +S-ML cell. For ...
  http://www.jneurosci.org/content/22/22/9945
*  New retinal ganglion cell subtypes emerge from single-cell RNA sequencing
... have identified 40 subtypes of retinal ganglion cells (RGCs) along with the genetic markers and transcription factors that ... Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of ... New retinal ganglion cell subtypes emerge from single-cell RNA sequencing. By Joyce Dall'Acqua Peterson UConn, JAX researchers ... Rheaume et al.: Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes. Nature ...
  https://www.jax.org/news-and-insights/2018/july/retinal-ganglion-cells-rna-sequencing
*  Reversal of Apoptosis in Retinal Ganglion Cells | IOVS | ARVO Journals
Reversal of Apoptosis in Retinal Ganglion Cells Farzana Rahman; Shereen Nizari; Joana Galvao; Miles Parnell; ABUBAKAR HABIB; ... Reversal of Apoptosis in Retinal Ganglion Cells You will receive an email whenever this article is corrected, updated, or cited ... Purpose: Early detection of retinal ganglion cell (RGC) apoptosis and its prevention holds promise as a novel and effective ... Reversal of Apoptosis in Retinal Ganglion Cells. Invest. Ophthalmol. Vis. Sci. 2013;54(15):434. ...
  https://iovs.arvojournals.org/article.aspx?articleid=2149191
*  Cells | Free Full-Text | Real-Time Imaging of Retinal Ganglion Cell Apoptosis
We review the current perspectives on retinal ganglion cell apoptosis, the way in which this can be imaged, and the exciting ... has developed a minimally invasive method using fluorescent annexin A5 to detect rates of apoptosis in retinal ganglion cells, ... The DARC (Detection of Apoptosing Retinal Cells) project ... in models of glaucoma and other conditions where retinal ... Keywords: retinal ganglion cell; apoptosis; neurodegeneration; glaucoma; annexin; imaging retinal ganglion cell; apoptosis; ...
  http://www.mdpi.com/2073-4409/7/6/60
*  Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo | Protocol
RNFL/GCL - retinal nerve fiber layer/ganglion cell layer, GC: ganglion cell. Figures A-C adapted from Sarzi et al.9. Please ... GC: ganglion cell, RNFL/GCL: retinal nerve fiber layer/ganglion cell layer, IPL: inner plexiform layer, INL: inner nuclear ... All approaches described here are designed for retinal ganglion cells (RGC) but are easily adaptable to other cell populations ... Retrograde Labeling of Retinal Ganglion Cells by Application of Fluoro-Gold on the Surface of Superior Colliculus…. Published 6 ...
  https://www.jove.com/video/55865/optical-coherence-tomography-imaging-mouse-retinal-ganglion-cells
*  Phototransduction in Photosensitive Retinal Ganglion Cells | IOVS | ARVO Journals
Phototransduction in Photosensitive Retinal Ganglion Cells You will receive an email whenever this article is corrected, ... Purpose: : The phototransduction cascade in melanopsin-expressing photosensitive retinal ganglion cells (pRGCs) is a subject of ... S. Sekaran, R. G. Foster, M. W. Hankins; Phototransduction in Photosensitive Retinal Ganglion Cells. Invest. Ophthalmol. Vis. ... However, at 50 µM OAG significantly suppressed the light response in 5 out of 17 cells. The remainder of the cells continued to ...
  http://iovs.arvojournals.org/article.aspx?articleid=2362989
*  Artemin augments survival and axon regeneration in axotomized retinal ganglion cells. | Sigma-Aldrich
Artemin, a specific ligand for GFRα3, has a neuroprotective effect on axotomized retinal ganglion cells (RGCs) in vivo and in ... Artemin augments survival and axon regeneration in axotomized retinal ganglion cells.. [Kazuko Omodaka, Takuji Kurimoto, Orie ... and spiral ganglion neurons both in vivo and in vitro. However, its effects on retinal cells and its intracellular signaling ... Artemin, a recently discovered member of the glial cell line-derived neurotrophic factor (GDNF) family, has neurotrophic ...
  https://www.sigmaaldrich.com/catalog/papers/25044131
*  Spatial Frequency Response of Rat Retinal Ganglion Cells | IOVS | ARVO Journals
In this study we examine the spatial receptive fields of different types of rat retinal ganglion cells (RGCs). Our results ... Spatial Frequency Response of Rat Retinal Ganglion Cells You will receive an email whenever this article is corrected, updated ... C. L. Passaglia, W. F. Heine; Spatial Frequency Response of Rat Retinal Ganglion Cells. Invest. Ophthalmol. Vis. Sci. 2009;50( ... The spatial frequency response of many of these cells was unimodal and showed orientation bias. Some cells displayed bimodal ...
  https://iovs.arvojournals.org/article.aspx?articleid=2363847
*  The Ultimate Guide To Daily health Tip - Blog
Intraocular stress is transmitted into the axons of retinal ganglion cells for the optic nerve as mechanical strain, resulting ... practically nothing acts like directions for your cells like your food stuff does. Sure foods can disrupt hormonal purpose And ... in cell death.. In PACG, the peripheral iris obstructs ordinary aqueous outflow (Determine 1).11 This may lead to amplified ...
  http://health-news37047.blogolize.com
*  CREUTZFELDT JAKOB DISEASE: July 2009
... cranial nerve ganglia, posterior eye (specifically the posterior hyaloid face, retina, retinal pigment epithelium, choroid, ... Conversion of human prion protein by CWD-associated prions has been demonstrated in an in vitro cell-free experiment, but ... They found the single cell. I mean, the biochemical part of both B.S.E. and variant were similar. We found the same biochemical ...
  http://creutzfeldt-jakob-disease.blogspot.com/2009_07_01_archive.html