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*  Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wld s ) | Genome...
Arruda-Carvalho M, Njaine B, Silveira MS, Linden R, Chiarini LB: Hop/STI1 modulates retinal proliferation and cell death ... The neuroprotective slow Wallerian degeneration (Wld s ) mutation delays degeneration in axonal and synaptic compartments of ... and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration. Cell Death Differ. 2007, 14 ... Wang AL, Yuan M, Neufeld AH: Degeneration of neuronal cell bodies following axonal injury in Wlds mice. J Neurosci Res. 2006, ...
  https://genomebiology.biomedcentral.com/articles/10.1186/gb-2008-9-6-r101
*  Be Knowledgeable About Age Related Macular Degeneration (AMD)
... which destroys the retinal cells and results in blind spots in the central vision. Often wet macular degeneration is the more ... Age Related Macular Degeneration Symptoms. The first warning signs of age related macular degeneration are usually blurriness ... Age related macular degeneration (AMD) is one of the leading causes of loss of vision in adults over age 65. AMD is a condition ... Dry macular degeneration is found more often and may be a result of aging and thinning of the macular tissues or pigment build- ...
  https://www.foxeyecareraleigh.com/2012/02/27/be-knowledgeable-about-age-related-macular-degeneration-amd/
*  Gene Therapy for Leber's Congenital Amaurosis
... for Europes first clinical trial in the use of stem cell drived-retinal pigment epithelium to treat macular degeneration. ... LCA Type 2, one of the more common types, is caused by a defect in the RPE65 gene (Retinal Pigment Epithelium-specific Protein ... James Bainbridge is an NIHR Research Professor and Professor of Retinal Studies at the UCL Institute of Ophthalmology. He has ... provides an update into gene therapy research into interventions for inherited retinal diseases including an update on the ...
  http://www.brcophthalmology.org/gene-therapy-lebers-congenital-amaurosis
*  Age Related Macular Degeneration | Wet AMD | Non-Neovascular Macular Degeneration
Non-Neovascular Macular Degeneration, Age Related Macular Degeneration is an Ophthalmology Disease that is Treated at the ... Abnormal sub-retinal or intra-retinal blood vessel growth. Lipofuscin - Waste products of retinal photoreceptor metabolism. ... Sub-Retinal Hemorrhage (SRH) - Blood below the retina. Sub-Retinal Fluid (SRF) - Fluid below the retina. Sub-Macular Hemorrhage ... Sub-RPE Fluid - Fluid below the retinal pigment epithelium. Sub-RPE Blood - Blood below the retinal pigment epithelium ...
  http://www.retinacenternj.com/diseases-treatment/age-related-macular-degeneration-wet-amd-or-non-ne
*  Phys.org - retinal degeneration
The loss of eyesight, often caused by retinal degeneration, is a life-altering health issue for many people, especially as they ... Most worrisome for many, however, is the potential loss of eyesight due to retinal degeneration. ... Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration ... Via its messengers-so-called melanopsin-expressing retinal ganglion cells, or mRGCs-it forwards information ... ...
  https://phys.org/tags/retinal+degeneration/sort/rank/all/
*  Breakthrough gene therapy prevents retinal degeneration
In a model simulating the progression of human retinal degeneration, the researchers treated mice with nanoparticles carrying a ... Nanoparticles, which are small enough to penetrate cells and stable enough to protect DNA, are capable of preventing retinal ...
  http://www.biologynews.net/archives/2010/08/17/breakthrough_gene_therapy_prevents_retinal_degeneration.html
*  GARP2 accelerates retinal degeneration in a mouse model | EurekAlert! Science News
... an important step toward creating a standardized nomenclature between mice and humans for a measurement of retinal degeneration ... Researchers show that GARP2 accelerates retinal degeneration in mice, and have made ... GARP2 accelerates retinal degeneration in a mouse model Researchers show that GARP2 accelerates retinal degeneration in mice, ... They followed retinal degeneration in these strains at three and 10 weeks, using OCT and light and transmission microscopy to ...
  https://www.eurekalert.org/pub_releases/2017-02/uoaa-gar021617.php
*  Dogs NSW - PRD - Progressive Retinal Degeneration
PRD - Progressive Retinal Degeneration Progressive retinal degeneration can slowly cause blindness in any dog of any breed, but ... Progressive retinal degeneration (PRD) is also known as progressive retinal atrophy (PRA) and refers to retinal diseases that ... Other breeds have a slowly progressive degeneration or death of the retinal tissue; this is degeneration. ... Progressive retinal degeneration may affect either the rods alone, the cones alone or both the rods and cones together. ...
  http://dogsnsw.org.au/resources/dogs-nsw-magazine/articles/health/259-prd-progressive-retinal-degeneration.html
*  Nanotechnology Now - Press Release: Breakthrough Gene Therapy Prevents Retinal Degeneration
Breakthrough Gene Therapy Prevents Retinal Degeneration. Boston, MA , Posted on August 16th, 2010. "Our work shows that it is ... In a model simulating the progression of human retinal degeneration, the researchers treated mice with nanoparticles carrying a ... "POD Nanoparticles Expressing GDNF Provide Structural and Functional Rescue of Light-Induced Retinal Degeneration in an Adult ... Nanoparticles, which are small enough to penetrate cells and stable enough to protect DNA, are capable of preventing retinal ...
  http://www.nanotech-now.com/news.cgi?story_id=39639
*  A model to study complement involvement in experimental retinal degeneration
... Mohlin, Camilla Linnaeus Univ, Linnaeus Ctr ... Method and materials: The adult porcine retina was co-cultured with the spontaneously arising human retinal pigment epithelial ... and age-related macular degeneration (AMD). Given that many of the complex eye-related degenerative diseases have limited ... treatment opportunities, we aimed to mimic the in vivo retinal degenerative process by developing a relevant co-culture system. ...
  http://www.diva-portal.org/smash/record.jsf?pid=diva2:1222549
*  Late-Onset Retinal Degeneration | Springer for Research & Development
Patients with late-onset retinal degeneration (LORD) usually present with nyctalopia in the fifth or sixth decade of life. The ... Tsang S.H., Sharma T. (2018) Late-Onset Retinal Degeneration. In: Tsang S., Sharma T. (eds) Atlas of Inherited Retinal Diseases ... Longitudinal structural changes in late-onset retinal degeneration. Retina. 2016;36:2348-56.CrossRefGoogle Scholar ... Patients with late-onset retinal degeneration (LORD) usually present with nyctalopia in the fifth or sixth decade of life. The ...
  https://rd.springer.com/chapter/10.1007%2F978-3-319-95046-4_23
*  Molecular Vision: Retinal degeneration increases susceptibility to myopia in mice
Variability in rate of cone degeneration in the retinal degeneration (rd/rd) mouse. Exp Eye Res. 1997; 65:45-50. [PMID: 9237863 ... Gargini C, Terzibasi E, Mazzoni F, Strettoi E. Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a ... Retinal degeneration increases susceptibility to myopia in mice. Hanna Park,1 Christopher C. Tan,1 Amanda Faulkner,1,3 Seema B ... these photoreceptor degeneration models, despite significantly lower DOPAC levels. However, the retinal degeneration models ...
  http://www.molvis.org/molvis/v19/2068/
*  Retinal degeneration and ageing
... and new interventions aimed at some of the UK's more prevalent eye conditions including age-related macular degeneration, ... Retinal degeneration and ageing. Age related eye disease accounts for more than 70% of all vision loss in the UK. ... This is key to understanding healthy and unhealthy retinal ageing.. Our work extends from basic physiology to clinical trials. ... electrophysiological techniques to probe all aspects of retinal form and function. ...
  http://www.cardiff.ac.uk/optometry-vision-sciences/research/research-themes/retinal-degeneration-and-ageing
*  Müller Cell Metabolic Chaos During Retinal Degeneration - Jonesblog
... retinal degeneration, retinal metabolism, retinitis pigmentosa, Robert E. Marc, Robert Marc, RP ... Müller Cell Metabolic Chaos During Retinal Degeneration. We have a new publication out (direct link, open access), Müller Cell ... Although retinal degeneration is certainly the trigger, Müller cell metabolic alterations are not a coherent response to the ... Metabolic Chaos During Retinal Degeneration authored by Rebecca Pfeiffer, Robert Marc, Mineo Kondo, Hiroko Terasaki and myself. ...
  http://prometheus.med.utah.edu/~bwjones/2016/05/muller-cell-metabolic-chaos-during-retinal-degeneration/
*  Zum Sudden Acquired Retinal Degeneration Syndrome (SARDS) beim Hund
... Zum Sudden Acquired Retinal Degeneration Syndrome (SARDS) ... Braus, Barbara Katharina (2008): Zum Sudden Acquired Retinal Degeneration Syndrome (SARDS) beim Hund. Dissertation, LMU München ... finally resembling dogs with severe generalised progressive retinal degeneration. In the second part of the study, the ... finally resembling dogs with severe generalised progressive retinal degeneration. In the second part of the study, the ...
  https://edoc.ub.uni-muenchen.de/8958/
*  Retinal degeneration - Wikipedia
The term retinal degeneration may refer to: One of several eye diseases or eye disorders in humans Progressive retinal atrophy ...
  https://en.wikipedia.org/wiki/Retinal_degeneration
*  Retinal Degeneration in Polycythaemia Mice | IOVS | ARVO Journals
Therefore, retinal iron deficiency may be the cause of the retinal degeneration in older Pcm homozygotes. ... Retinal Degeneration in Polycythaemia Mice You will receive an email whenever this article is corrected, updated, or cited in ... J. Iacovelli, M. Nassar, A. Schumacher, J. L. Dunaief; Retinal Degeneration in Polycythaemia Mice. Invest. Ophthalmol. Vis. Sci ... Conclusions:: Increased levels of Fpn in the RPE at 7 weeks may promote excessive retinal iron export causing low retinal iron ...
  https://iovs.arvojournals.org/article.aspx?articleid=2387182
*  Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation | PNAS
Degeneration of the outer retina resulting in sight loss may occur in retinitis pigmentosa (RP) and other retinal degenerations ... 2005) Retinal remodeling during retinal degeneration. Exp Eye Res 81(2):123-137. ... Müller cells play a role in photoreceptor function (16), and, additionally in retinal degeneration, an outer retinal glial ... 1990) Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase. Nature 347( ...
  https://www.pnas.org/content/110/3/1101.full
*  Drugs already on market prevent light-induced retinal degeneration in mice | National Eye Institute
Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal ... Drugs already on market prevent light-induced retinal degeneration in mice. NEI-funded study points to a novel approach for ... The loss of retinal function causes blindness in diseases such as age-related macular degeneration and Stargardt disease, the ... Home , News , Briefs , Drugs already on market prevent light-induced retinal degeneration in mice ...
  https://www.nei.nih.gov/news/briefs/drugs-already-market-prevent-light-induced-retinal-degeneration-mice
*  Retinal degeneration | Article about Retinal degeneration by The Free Dictionary
Find out information about Retinal degeneration. A carotenoid, produced as an intermediate in the bleaching of rhodopsin and ... Also known as vitamin A aldehyde Explanation of Retinal degeneration ... retinal. (redirected from Retinal degeneration). Also found in: Dictionary, Thesaurus, Medical.. Related to Retinal ... cataract, retinal detachment, vitreous degeneration, retinal degeneration and glaucoma.. Electroretinography (ERG) for Clinical ...
  http://encyclopedia2.thefreedictionary.com/Retinal+degeneration
*  Notable Paper: Tauroursodeoxycholic Acid (TUDCA) Prevents Retinal Degeneration in Transgenic P23H Rats - Webvision
Part XII: Investigations of Human Retinal Disease *Retinal Degeneration, Remodeling and Plasticity by Bryan William Jones, ... Part VI: Retinal Neurogenesis: Early stages in the development of neurons and pathways *Formation of Early Retinal Circuits in ... This paper in IOVS, "Tauroursodeoxycholic Acid (TUDCA) Prevents Retinal Degeneration in Transgenic P23H Rats" by Laura ... Notable Paper: Tauroursodeoxycholic Acid (TUDCA) Prevents Retinal Degeneration in Transgenic P23H Rats. ...
  https://webvision.med.utah.edu/2011/05/tauroursodeoxycholic-acid-tudca-prevents-retinal-degeneration-in-transgenic-p23h-rats/
*  Genes | Free Full-Text | Target 5000: Target Capture Sequencing for Inherited Retinal Degenerations
There are an estimated 5000 people in Ireland who currently have an inherited retinal degeneration (IRD). It is the goal of ... Target 5000: Target Capture Sequencing for Inherited Retinal Degenerations. Adrian Dockery 1,* , Kirk Stephenson 2. ... There are an estimated 5000 people in Ireland who currently have an inherited retinal degeneration (IRD). It is the goal of ... "Target 5000: Target Capture Sequencing for Inherited Retinal Degenerations." Genes 8, no. 11: 304. ...
  https://www.mdpi.com/2073-4425/8/11/304
*  Search of: 'Retinoschisis' OR 'Retinal Degeneration' OR 'X-linked juvenile retinoschisis' - List Results - ClinicalTrials.gov
Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration. *Retinal Degenerations ... Retinal Imaging in Patients With Inherited Retinal Degenerations. *Retinitis Pigmentosa. Observational. Phase 1. *University of ... Argus® II Retinal Prosthesis System Post-Market Surveillance Study. *Outer Retinal Degeneration ... Impact of inherited retinal degeneration on quality of life measures.. *Effect of contrast sensitivity function on quality of ...
  https://clinicaltrials.gov/ct2/results?cond=%22Retinoschisis%22%20OR%20%22Retinal%20Degeneration%22%20OR%20%22X-linked%20juvenile%20retinoschisis%22
*  Refined mapping of canine early retinal degeneration | IOVS | ARVO Journals
A.V. Kukekova, J.L. Nelson, E.F. Kirkness, G.D. Aguirre, G.M. Acland; Refined mapping of canine early retinal degeneration . ... Refined mapping of canine early retinal degeneration You will receive an email whenever this article is corrected, updated, or ... Early retinal degeneration (erd) of Norwegian elkhounds is an autosomal recessive, early onset form of PRA. In previous studies ...
  http://iovs.arvojournals.org/article.aspx?articleid=2410268
*  Retinal degeneration (rhodopsin mutation) - Wikipedia
"A Novel Form of Transducin-Dependent Retinal Degeneration: Accelerated Retinal Degeneration in the Absence of Rod Transducin". ... "A Novel Form of Transducin-Dependent Retinal Degeneration: Accelerated Retinal Degeneration in the Absence of Rod Transducin". ... "A Novel Form of Transducin-Dependent Retinal Degeneration: Accelerated Retinal Degeneration in the Absence of Rod Transducin". ... "A Novel Form of Transducin-Dependent Retinal Degeneration: Accelerated Retinal Degeneration in the Absence of Rod Transducin". ...
  https://en.wikipedia.org/wiki/Retinal_degeneration_(rhodopsin_mutation)