*  Correlation of Outer Nuclear Layer Thickness With Cone Density Values in Patients With Retinitis Pigmentosa and Healthy...
Retinal remodeling processes might lead to thickening of retinal layers despite photoreceptor degeneration.29,30 Including ... Carroll J. Adaptive optics retinal imaging: applications for studying retinal degeneration. Arch Ophthalmol. 2008; 126: 857-858 ... Pennesi ME Michaels KV Magee SS Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain ... Duncan JL Talcott KE Ratnam K Cone structure in retinal degeneration associated with mutations in the peripherin/RDS gene. ...
  http://iovs.arvojournals.org/article.aspx?articleid=2212769
*  Dogs NSW - PRD - Progressive Retinal Degeneration
Progressive retinal degeneration (PRD) is also known as progressive retinal atrophy (PRA) and refers to retinal diseases that ... Other breeds have a slowly progressive degeneration or death of the retinal tissue; this is degeneration. ... Progressive retinal degeneration can slowly cause blindness in any dog of any breed, but learning about the condition is the ... Progressive retinal degeneration may affect either the rods alone, the cones alone or both the rods and cones together. ...
  http://dogsnsw.org.au/resources-sp-1371102451/dogs-nsw-magazine/articles/health/259-prd-progressive-retinal-degeneration.html
*  Retinal degeneration in motor neuron degeneration: a mouse model of c" by B Chang, R T. Bronson et al.
METHODS: In screening the mnd/mnd mouse for ocular disease, a retinal degeneration was found that was evaluated by serial ... Genetic analyses show that the retinal degeneration in mnd mice is inherited as a single autosomal gene with recessive ... and a three-point cross placed the retinal degeneration at the mnd locus on the proximal end of mouse chromosome 8. Crosses ... and provides a good model for the retinal degeneration found in these patients. ...
  https://mouseion.jax.org/stfb1990_1999/495/
*  JCI - WNT signaling determines tumorigenicity and function of ESC-derived retinal progenitors
SI-induced retinal degeneration model and subretinal transplant surgery. Experimental C57BL/6 mice at 8 weeks of age were used ... In this study, through functional evaluation of multiple kinds of ESC-RPCs in comparison with P-RPCs in a retinal degeneration ... Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration. Exp Eye ... Kiuchi K, Yoshizawa K, Shikata N, Moriguchi K, Tsubura A. Morphologic characteristics of retinal degeneration induced by sodium ...
  https://www.jci.org/articles/view/65048
*  Exercise may slow progression of retinal degeneration - LinkOPH
Exercise may slow progression of retinal degeneration. by Medical News Today • 2014/02/11. • 0 Comments ... The findings suggest exercise may be able to slow the progression of retinal degenerative diseases. Full Story → ...
  http://www.linkoph.com/2014/02/11/exercise-may-slow-progression-of-retinal-degeneration/
*  Targeting Caspase-12 to Preserve Vision in Mice With Inherited Retinal Degeneration | IOVS | ARVO Journals
Marigo V. Programmed cell death in retinal degeneration: targeting apoptosis in photoreceptors as potential therapy for retinal ... It has been proposed that in the case of retinal degeneration caused by expression of aberrant rhodopsin, an imbalance in Ca2+ ... Modulation of the rate of retinal degeneration in T17M RHO mice by reprogramming the unfolded protein response. Adv Exp Med ... ER stress in retinal degeneration in S334ter Rho rats. PLoS One. 2012; 7: e33266. ...
  http://iovs.arvojournals.org/article.aspx?articleid=2411354
*  Identification of miRNAs in a Model of Retinal Degenerations | IOVS | ARVO Journals
Phototoxic-induced photoreceptor degeneration causes retinal ganglion cell degeneration in pigmented rats. J Comp Neurol. 2006 ... maintaining the retinal circadian cycle and having a protective role in bright light-induced retinal degeneration.57,58 Unlike ... triggered as a result of the acute retinal damage, which is a key mediator of retinal degeneration in this model and age- ... has been well documented in retinal degenerations, including AMD as a response to intense retinal stress.28-30 While ...
  http://iovs.arvojournals.org/article.aspx?articleid=2277022
*  Inactivation of the Akt Survival Pathway during Photoreceptor Apoptosis in the Retinal Degeneration Mouse | IOVS | ARVO Journals
... seventy years of research on an animal model of inherited retinal degeneration.OsborneNN ChaderGJ eds. Progress in Retinal and ... Apoptotic cell death in retinal degenerations. Prog Retin Eye Res. 1998;17:443-464. [CrossRef] [PubMed] ... Analysis of neurological mutants with inherited retinal degeneration. Invest Ophthalmol Vis Sci. 1981;21:638-657. [PubMed] ... Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene. Graefes Arch Clin Exp ...
  http://iovs.arvojournals.org/article.aspx?articleid=2202966
*  Mechanisms and Therapeutic Treatments for Inherited Retinal Degenerative Diseases - Robert Molday
Inherited retinal degenerative diseases (RDDs) are a heterogeneous group of disorders that constitute a major cause of vision ... Stargardt macular degeneration and Leber Congenital Amaurosis Type 12 are early onset retinal degenerative diseases which cause ... 2015) Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads ... 2015) Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium. Invest ...
  http://grantome.com/grant/NIH/R01-EY002422-33
*  Diagnosis of retinal degeneration: Costs for treatment #239645 in Germany | BookingHealth
Diagnosis of retinal degeneration (costs for program #239645) ✔ University Hospital Hamburg-Eppendorf ✔ Department of ... University Hospital Hamburg-Eppendorf › Diagnosis of retinal degeneration: Costs for treatment #239645 in Germany - ... laser doppler retinal vessels,\/li,\n\t\t,li,electron microscopy of retinal capillaries,\/li,\n\t,\/ul,\n\t,\/li,\n\t,li, ... Diagnosis of retinal degeneration','price':{'val':0,'type':'val'},'extra_service_clinic':[],'extra_service':[],'translation_ ...
  https://bookinghealth.com/university-hospital-hamburg-eppendorf/diagnostic-programs/239645-diagnosis-of-retinal-degeneration.html
*  Cell-Based Therapy (CBT) | blindness.org
Scientists and clinicians are testing treatments for retinal degenerative diseases with stem cell and retinal transplants. This ... therapy has the potential to treat all retinal degenerative diseases, even in those people who have completely lost all ... Using cell transplants or stem cells to treat a retinal degenerative disease. Cell-Based Therapy (CBT) is one of the ... Scientists and clinicians are testing treatments for retinal degenerative diseases with stem cell and retinal transplants. This ...
  http://www.blindness.org/glossary/cell-based-therapy-cbt
*  174delG Mutation in Mouse MFRP Causes Photoreceptor Degeneration and RPE Atrophy | IOVS | ARVO Journals
A subset of mice with retinal degeneration was identified in a histologic screen of Per3 −/− animals on a 129/Sv background 20 ... 6D). We therefore conclude that intact RPE of Mfrp 174delG animals, before the onset of retinal degeneration and RPE atrophy, ... Retinal Cell Biology , September 2011. 174delG Mutation in Mouse MFRP Causes Photoreceptor Degeneration and RPE Atrophy ... A) rdx animals exhibit progressive retinal degeneration. Note the presence of an aberrant pigmented cell among the distal tips ...
  http://iovs.arvojournals.org/article.aspx?articleid=2165473
*  Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence...
Conclusions: Retinal layer thickness can be quantified longitudinally throughout the course of retinal degeneration in the RCS ... Histologic analysis of retinal tissue has been considered the gold standard for characterizing retinal degeneration and ... Purpose: Prospective treatments for age-related macular degeneration and inherited retinal degenerations are commonly evaluated ... Discordant anatomical, electrophysiological, and visual behavioral profiles of retinal degeneration in rat models of retinal ...
  http://iovs.arvojournals.org/article.aspx?articleid=2608341
*  Pain Medicine Appears To Preserve Vision In Model of Inherited Retinal Degeneration - The Generic Whiz
... pain medicine that potently activates a receptor vital to a healthy retina assist preserve vision in a model of severe retinal ... Pain Medicine Appears To Preserve Vision In Model of Inherited Retinal Degeneration June 28, 2016. GW Editorial Staff 0 ... It is a model of severe inherited retinal degeneration like retinitis pigmentosa. The researchers injected the drug into the ... News Source, Pain medicine helps preserve vision in model of inherited retinal degeneration ...
  http://thegenericwhiz.com/pain-medicine-preserve-vision-in-model-of-inherited-retinal-degeneration/
*  Diagnostics of retinal degeneration: Costs for treatment #248377 in Germany | BookingHealth
Diagnostics of retinal degeneration (costs for program #248377) ✔ University Hospital Halle (Saale) ✔ Department of ... Retina degeneration University Hospital Halle (Saale) offers the following treatment of your disease: Retina degeneration ... University Hospital Halle (Saale) › Diagnostics of retinal degeneration: Costs for treatment #248377 in Germany - BookingHealth ... laser doppler retinal vessels,\/li,\n\t\t,li,electron microscopy of retinal capillaries,\/li,\n\t,\/ul,\n\t,\/li,\n\t,li, ...
  https://bookinghealth.com/university-hospital-halle-saale/diagnostic-programs/248377-diagnostics-of-retinal-degeneration.html
*  Phys.org - retinal degeneration
The loss of eyesight, often caused by retinal degeneration, is a life-altering health issue for many people, especially as they ... Most worrisome for many, however, is the potential loss of eyesight due to retinal degeneration. ... Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration ... Via its messengers-so-called melanopsin-expressing retinal ganglion cells, or mRGCs-it forwards information ... ...
  https://phys.org/tags/retinal+degeneration/sort/rank/all/
*  GARP2 accelerates retinal degeneration in a mouse model | EurekAlert! Science News
... an important step toward creating a standardized nomenclature between mice and humans for a measurement of retinal degeneration ... Researchers show that GARP2 accelerates retinal degeneration in mice, and have made ... GARP2 accelerates retinal degeneration in a mouse model Researchers show that GARP2 accelerates retinal degeneration in mice, ... They followed retinal degeneration in these strains at three and 10 weeks, using OCT and light and transmission microscopy to ...
  https://www.eurekalert.org/pub_releases/2017-02/uoaa-gar021617.php
*  Dogs NSW - PRD - Progressive Retinal Degeneration
PRD - Progressive Retinal Degeneration Progressive retinal degeneration can slowly cause blindness in any dog of any breed, but ... Progressive retinal degeneration (PRD) is also known as progressive retinal atrophy (PRA) and refers to retinal diseases that ... Other breeds have a slowly progressive degeneration or death of the retinal tissue; this is degeneration. ... Progressive retinal degeneration may affect either the rods alone, the cones alone or both the rods and cones together. ...
  http://dogsnsw.org.au/resources/dogs-nsw-magazine/articles/health/259-prd-progressive-retinal-degeneration.html
*  Nanotechnology Now - Press Release: Breakthrough Gene Therapy Prevents Retinal Degeneration
Breakthrough Gene Therapy Prevents Retinal Degeneration. Boston, MA , Posted on August 16th, 2010. "Our work shows that it is ... In a model simulating the progression of human retinal degeneration, the researchers treated mice with nanoparticles carrying a ... "POD Nanoparticles Expressing GDNF Provide Structural and Functional Rescue of Light-Induced Retinal Degeneration in an Adult ... Nanoparticles, which are small enough to penetrate cells and stable enough to protect DNA, are capable of preventing retinal ...
  http://www.nanotech-now.com/news.cgi?story_id=39639
*  Müller Cell Metabolic Chaos During Retinal Degeneration - Jonesblog
... retinal degeneration, retinal metabolism, retinitis pigmentosa, Robert E. Marc, Robert Marc, RP ... Müller Cell Metabolic Chaos During Retinal Degeneration. We have a new publication out (direct link, open access), Müller Cell ... Although retinal degeneration is certainly the trigger, Müller cell metabolic alterations are not a coherent response to the ... Metabolic Chaos During Retinal Degeneration authored by Rebecca Pfeiffer, Robert Marc, Mineo Kondo, Hiroko Terasaki and myself. ...
  http://prometheus.med.utah.edu/~bwjones/2016/05/muller-cell-metabolic-chaos-during-retinal-degeneration/
*  Retinal Degeneration in Polycythaemia Mice | IOVS | ARVO Journals
Therefore, retinal iron deficiency may be the cause of the retinal degeneration in older Pcm homozygotes. ... Retinal Degeneration in Polycythaemia Mice You will receive an email whenever this article is corrected, updated, or cited in ... J. Iacovelli, M. Nassar, A. Schumacher, J. L. Dunaief; Retinal Degeneration in Polycythaemia Mice. Invest. Ophthalmol. Vis. Sci ... Conclusions:: Increased levels of Fpn in the RPE at 7 weeks may promote excessive retinal iron export causing low retinal iron ...
  https://iovs.arvojournals.org/article.aspx?articleid=2387182
*  Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation | PNAS
Degeneration of the outer retina resulting in sight loss may occur in retinitis pigmentosa (RP) and other retinal degenerations ... 2005) Retinal remodeling during retinal degeneration. Exp Eye Res 81(2):123-137. ... Müller cells play a role in photoreceptor function (16), and, additionally in retinal degeneration, an outer retinal glial ... 1990) Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase. Nature 347( ...
  http://www.pnas.org/content/110/3/1101
*  Drugs already on market prevent light-induced retinal degeneration in mice | National Eye Institute
Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal ... Drugs already on market prevent light-induced retinal degeneration in mice. NEI-funded study points to a novel approach for ... The loss of retinal function causes blindness in diseases such as age-related macular degeneration and Stargardt disease, the ... Home , News , Briefs , Drugs already on market prevent light-induced retinal degeneration in mice ...
  https://www.nei.nih.gov/news/briefs/drugs-already-market-prevent-light-induced-retinal-degeneration-mice
*  Search of: 'Retinoschisis' OR 'Retinal Degeneration' OR 'X-linked juvenile retinoschisis' - List Results - ClinicalTrials.gov
Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration. *Retinal Degenerations ... Retinal Imaging in Patients With Inherited Retinal Degenerations. *Retinitis Pigmentosa. Observational. Phase 1. *University of ... Argus® II Retinal Prosthesis System Post-Market Surveillance Study. *Outer Retinal Degeneration ... Impact of inherited retinal degeneration on quality of life measures.. *Effect of contrast sensitivity function on quality of ...
  https://clinicaltrials.gov/ct2/results?cond=%22Retinoschisis%22%20OR%20%22Retinal%20Degeneration%22%20OR%20%22X-linked%20juvenile%20retinoschisis%22
*  Refined mapping of canine early retinal degeneration | IOVS | ARVO Journals
A.V. Kukekova, J.L. Nelson, E.F. Kirkness, G.D. Aguirre, G.M. Acland; Refined mapping of canine early retinal degeneration . ... Refined mapping of canine early retinal degeneration You will receive an email whenever this article is corrected, updated, or ... Early retinal degeneration (erd) of Norwegian elkhounds is an autosomal recessive, early onset form of PRA. In previous studies ...
  http://iovs.arvojournals.org/article.aspx?articleid=2410268