*  Southern California Conferences for Undergraduate Research - Southern California Conferences for Undergraduate Research: Effect...
The current study is aimed at investigating the potential role of kappa opioid receptor activation in the response to METH in ... METH was administered in the presence or absence of norbinaltorphimine (nor-BNI), a kappa opioid receptor antagonist, and ... Key words: kappa receptors, laboratory rats, locomotor behavior, methamphetamine, opioid antagonist, ultrasonic vocalizations ... However, recent findings suggest that endogenous opioids are also affected by psychomotor stimulants such as METH, and that ...
  https://www.sccur.org/sccur/fall_2017_conference/poster_2/34/
*  Oprk1 - Kappa-type opioid receptor - Mus musculus (Mouse) - Oprk1 gene & protein
Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes ... Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of ... Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. ... G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low ...
  http://www.uniprot.org/uniprot/P33534
*  Human OPRK1-FLAG Stable Cell Line-CHO - Creative Biogene
The κ-opioid receptor is one of five related receptors that bind opium-like compound ... The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. ... OPRK1; opioid receptor, kappa 1; kappa-type opioid receptor; KOR; KOR-1; K-OR-1; kappa opioid receptor; Opiate receptor, kappa- ... kappa Opioid Receptor (KOR) is a receptor for dynorphins. KOR inhibits neurotransmitter release by reducing calcium currents ...
  https://www.creative-biogene.com/Human-OPRK1-FLAG-Stable-Cell-Line-CHO-CSC-RG0342-195240-11.html
*  Neuromics: Opioid Receptor Antibodies Trifecta
Delta Opioid Receptors Antibody, DOR Antibody, Kappa Opioid Antibody, KOR Antibody, MOR Antibody, Mu Opioid Receptor Antibodies ... This publication proposes a role for opioid receptors in treating cancers. It also references use of our μ, δ, and κ opioid ... Nuclei are stained with DAPI (blue). Top, opioid (green) receptors (green); middle, CD31 (red); bottom, merged. Scale bars, 100 ... Purinergic Receptors Antibodies (3) Rett Syndrome (1) RNAi (2) S100A13 (1) Schwann Cells (5) siRNA delivery in-vivo (9) ...
  http://neuromics.blogspot.com/2011/08/opioid-receptor-antibodies-trifecta.html
*  Behavioral and Neuroendocrine Effects of a Selective Kappa Opioid Receptor Antagonist | Clinical Research Trial Listing (...
New life-saving treatments for Addictions in clinical trial on Behavioral and Neuroendocrine Effects of a Selective Kappa ... Behavioral and Neuroendocrine Effects of a Selective Kappa Opioid Receptor Antagonist Brief description of study. Behavioral ... and Neuroendocrine Effects of a Selective Kappa Opioid Receptor Antagonist Detailed Study Description. The study you are ...
  http://www.centerwatch.com/clinical-trials/listings/140302/behavioral-and-neuroendocrine-effects-of-a-selective-kappa-opioid-receptor-antagonist-2/?&radius=50
*  OPRK1 polyclonal antibody - (PAB26567) - Products - Abnova
Opiate receptor, kappa-1,kappa opioid receptor. *Gene Pathway. *Neuroactive ligand-receptor interaction ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=PAB26567
*  Human OPRK1-FLAG Stable Cell Line-CHO CSC-RG0342 - Creative BioMart
... kappa 1 (OPRK1) tagged in the N-terminus with FLAG to allow stably express of the human OPRK1 tagged in the N-terminus with ... CHO-HuOPRK1-FLAG is clonally-derived from a CHO-K1 cell line which has been transfected with a human opioid receptor, ... OPRK1; opioid receptor, kappa 1; kappa-type opioid receptor; KOR; KOR-1; K-OR-1; kappa opioid receptor; Opiate receptor, kappa- ... kappa Opioid Receptor (KOR) is a receptor for dynorphins. KOR inhibits neurotransmitter release by reducing calcium currents ...
  https://www.creativebiomart.net/description_145736_196.htm
*  Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues. | Journal of Pharmacology and...
The effect of dexamethasone on acute opiate withdrawal induced by mu, kappa and delta receptor agonists was investigated in ... which suggest an important functional interaction between corticosteroids and the opioid system primarily at the mu receptor ... Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues.. A Capasso, A Di Giannuario, A ... Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues.. A Capasso, A Di Giannuario, A ...
  http://jpet.aspetjournals.org/content/276/2/743
*  Morphine Withdrawal Enhances Constitutive μ-Opioid Receptor Activity in the Ventral Tegmental Area | Journal of Neuroscience
1988) Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. J Pharmacol Exp ... micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor. Synapse 64:280-288. ... Endogenous opioids acting at the μ-opioid receptor (MOR) serve a pivotal function in reward processing and addictive behaviors ... 2002) Motivational effects of cannabinoids are mediated by μ-opioid and κ-opioid receptors. J Neurosci 22:1146-1154. ...
  http://www.jneurosci.org/content/32/46/16120
*  Cara Therapeutics to Announce First Quarter 2014 Financial Results on May 12, 2014
... focused on developing and commercializing new chemical entities designed to alleviate pain by selectively targeting kappa ... opioid receptors, announced today that the Company will host a conference call and live audio webcast on Monday, May 12, 2014, ... commercializing new chemical entities designed to alleviate pain and pruritus by selectively targeting kappa opioid receptors. ... developing and commercializing new chemical entities designed to alleviate pain by selectively targeting kappa opioid receptors ...
  https://www.cnbc.com/2014/05/05/globe-newswire-cara-therapeutics-to-announce-first-quarter-2014-financial-results-on-may-12-2014.html
*  Anti-Kappa Opioid Receptor antibody (ab113533) Protocols | Abcam
Abcam provides specific protocols for Anti-Kappa Opioid Receptor antibody (ab113533) : Western blot protocols, ...
  http://www.abcam.com/kappa-opioid-receptor-antibody-ab113533-protocols.html
*  Pharmacological properties of JDTic: A novel kappa-opioid receptor antagonist | RTI
... the first potent K-selective opioid receptor antagonist not derived from an opiate class of compounds. In the mouse tail-flick ... When JDTic was administered either s.c. or p.o. 24 h before the selective KOP (kappa)-opioid receptor agonist, enadoline, AD( ... A novel kappa-opioid receptor antagonist. European Journal of Pharmacology, 501(1-3), 111-119. DOI: 10.1016/j.ejphar.2004.08. ... In contrast, JDTic, s.c., failed to antagonize the analgesic effects of the selective MOP (mu)-opioid receptor agonist, ...
  https://www.rti.org/publication/pharmacological-properties-jdtic-novel-kappa-opioid-receptor-antagonist
*  Kappa opioid receptor activation decreases inhibitory transmission and antagonizes alcohol effects in rat central amygdala. -...
Kappa opioid receptor activation decreases inhibitory transmission and antagonizes alcohol effects in rat central amygdala.. ... Activation of the kappa opioid receptor (KOR) system mediates negative emotional states and considerable evidence suggests that ... Kappa Opioid Receptor Activation Decreases Inhibitory Transmission and Antagonizes Alcohol Effects in Rat Central Amygdala ... Kappa Opioid Receptor Activation Decreases Inhibitory Transmission and Antagonizes Alcohol Effects in Rat Central Amygdala ...
  https://www.ncbi.nlm.nih.gov/pubmed/24157490
*  Kappa opioid receptor activity in spontaneously hypertensive rats. | Journal of Pharmacology and Experimental Therapeutics
Kappa opioid receptor activity in spontaneously hypertensive rats. Message Subject (Your Name) has forwarded a page to you from ... Kappa opioid receptor activity in spontaneously hypertensive rats.. H N Bhargava and A Gulati ... Kappa opioid receptor activity in spontaneously hypertensive rats.. H N Bhargava and A Gulati ... Kappa opioid receptor activity in spontaneously hypertensive rats.. H N Bhargava and A Gulati ...
  http://jpet.aspetjournals.org/content/245/2/460
*  Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study. - PubMed - NCBI
The mu, delta, and kappa opioid receptors are the three main types of opioid receptors found in the central nervous system (CNS ... Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study.. Mansour A1, Fox CA, Burke ... Cells expressing kappa receptor mRNA demonstrate a third pattern of expression, with cells localized in regions such as the ... This study examines the expression of mu, delta, and kappa receptor mRNAs in the rat brain and spinal cord using in situ ...
  https://www.ncbi.nlm.nih.gov/pubmed/7884049?access_num=7884049&link_type=MED&dopt=Abstract
*  AID 148750 - Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig...
Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membrane. ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/148750
*  Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse...
Specifically, recent findings suggest that the kappa-opioid receptor (KOR) may play a role in aspects of nicotine dependence, ... Rationale Several lines of evidence support a role for the endogenous opioid system in mediating behaviors associated with drug ... Jackson, K. L., Carroll, F., Negus, S. S., & Damaj, M. I. (2010). Effect of the selective kappa-opioid receptor antagonist ... Specifically, recent findings suggest that the kappa-opioid receptor (KOR) may play a role in aspects of nicotine dependence, ...
  https://www.rti.org/publication/effect-selective-kappa-opioid-receptor-antagonist-jdtic-nicotine-antinociception-reward
*  Abstract 33: The Effects of Global Ischemia/Reperfusion Injury on Expressions of Kappa-Opioid Receptor in Myocardium in Cardiac...
Abstract 33: The Effects of Global Ischemia/Reperfusion Injury on Expressions of Kappa-Opioid Receptor in Myocardium in Cardiac ... Abstract 33: The Effects of Global Ischemia/Reperfusion Injury on Expressions of Kappa-Opioid Receptor in Myocardium in Cardiac ... Abstract 33: The Effects of Global Ischemia/Reperfusion Injury on Expressions of Kappa-Opioid Receptor in Myocardium in Cardiac ... Abstract 33: The Effects of Global Ischemia/Reperfusion Injury on Expressions of Kappa-Opioid Receptor in Myocardium in Cardiac ...
  http://circ.ahajournals.org/content/122/Suppl_21/A33
*  AID 552824 - Agonist activity at kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding assay relative to...
Agonist activity at kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding assay relative to salvinorin A. ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/552824
*  AID 488935 - SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay -...
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 6. ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/488935
*  Isolation and chemical modification of clerodane diterpenoids from Salvia species as potential agonists at the kappa-opioid...
... and kappa-opioid receptors. However, none of these compounds showed significant binding to any of the opioid-receptor subtypes ... has been reported to be a potent agonist at the kappa-opioid receptor. Computer modeling suggested that splendidin (2) from S. ... and chemical modification of clerodane diterpenoids from Salvia species as potential agonists at the kappa-opioid receptor. ... and chemical modification of clerodane diterpenoids from Salvia species as potential agonists at the kappa-opioid receptor. ...
  http://opus.bath.ac.uk/4578/
*  Fat cells fight disease, Purdue University researchers find | EurekAlert! Science News
Activation of this receptor by its ligand in the macrophage causes the activation and translocation of nuclear factor kappa-B ( ... Vaping popular among teens; opioid misuse at historic lows NIH/National Institute on Drug Abuse ... that will activate or suppress the LPS receptor. "We know there are non-infectious ligands that activate the receptor, so we ... This binding with the receptor molecule on the pig fat cell, like a key in a lock, signals fat cells to produce more of another ...
  https://www.eurekalert.org/pub_releases/2004-01/pu-fcf012004.php