... a receptor subunit also shared by the receptors for interleukin 2 (IL2), interleukin 7 (IL7) and interleukin 15 (IL15). This ... The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors ... 2000). "Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain". Proc. Natl. Acad. Sci. U.S.A. 97 ( ... 2005). "Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity". Mol. Cell ...
... insulin like growth factor 1 receptor; IL-21R: Interleukin 21 receptor; MALAT1: Metastasis-associated lung adenocarcinoma ... Transient receptor potential cation channel subfamily M member 3; UPF1: UPF1 RNA helicase and ATPase; ZFP91: Zinc finger ... Erb-b2 receptor tyrosine kinase 3; ERK: Extracellular signal-regulated kinase; EMT: Epithelial-mesenchymal transition; EZH2: ... C-C Motif Chemokine Ligand 21; ceRNA: Competitive endogenous RNA; EGFL7: Epidermal growth factor-like domain-containing protein ...
interleukin 1 receptor antagonist. treatment. ISO. mouse gene in a rat model. RGD. PMID:15795329. RGD:8551728. NCBI chr 3: ... interleukin 18 receptor 1. ISO. ClinVar Annotator: match by term: Behcet disease. ClinVar. PMID:25741868. NCBI chr 9:42,727,416 ... interleukin 1 receptor antagonist. ISO. protein:increased expression:serum. RGD. PMID:14600787. RGD:7401213. NCBI chr 3: ... interleukin 23 receptor. susceptibility. ISO. DNA:SNP: :rs1884444(human). DNA:SNPs,haplotype::rs17375018, rs11209032(human);. ...
Toll-like receptor 2 (TLR2) detects the SARS-CoV-2 envelope protein and generates inflammatory cytokines Researchers at St Jude ... A team of scientists from the USA and Belgium has recently revealed that the ErbB family of receptor tyrosine kinases play a ... lifecycle in host cells and that inhibition of these receptors can protect against SARS-CoV-2-induced acute and chronic lung ... Childrens Research Hospital found that toll-like receptor 2 detects the SARS-CoV-2 envelope protein-producing inflammatory ...
SIV-infected rhesus macaques that sequential interleukin-21 and interferon alpha therapy generate terminally  ... of differentiated NK cell populations in a pathogenic Rhesus macaque model of SIV infection and show administration of IL-21 ... Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc. Natl Acad. Sci. USA 99, 8826-8831 ( ... Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques. J. Clin. Invest 125, 4497- ...
cytokine receptor family 2 member 8. interleukin 20 receptor alpha subunit. interleukin 20 receptor, alpha. interleukin-20 ... IL20RA interleukin 20 receptor subunit alpha [Homo sapiens] IL20RA interleukin 20 receptor subunit alpha [Homo sapiens]. Gene ... The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This ... Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III. * NM_001278723.3 → NP_001265652.2 interleukin-20 receptor ...
Event=alternative splicing; named isoforms=3; name=h20; isoid=p16871-1; sequence=displayed; name=h1; isoid=p16871-2; sequence=vsp_001714; name=h6; synonyms=secreted; isoid=p16871-3; sequence=vsp_001713;. ...
Article Soluble Interleukin-2 Receptor and Urinary Neopterin Concentrations in Malignant Lymphoma was published on January 1, ... Soluble Interleukin-2 Receptor and Urinary Neopterin Concentrations in Malignant Lymphoma. * L. Piccinini , Sandra Zironi , ... Piccinini L, Zironi S, Cenci A, Campioli D, Federico M, Barbieri F. Soluble Interleukin-2 Receptor and Urinary Neopterin ... Piccinini, L., Zironi, S., Cenci, A., Campioli, D., Federico, M. and Barbieri, F. (1993) Soluble Interleukin-2 Receptor and ...
Description: A Guinea polyclonal antibody against Rabbit Interleukin 1 Receptor Antagonist (IL1RA). This antibody is labeled ... GABA A Receptor α3 Rabbit Polyclonal Antibody. GABA A Receptor ?2 Polyclonal Antibody. ... Description: A Guinea polyclonal antibody against Rabbit Interleukin 1 Receptor Antagonist (IL1RA). This antibody is labeled ... Description: A Guinea polyclonal antibody against Rabbit Interleukin 1 Receptor Antagonist (IL1RA). This antibody is labeled ...
IL-21R is a type-1 cytokine receptor and belongs to the IL-2R and IL-15R family. The signaling mechanisms of IL-21 in different ... In this chapter, we will focus on IL-21s biological effects and signaling pathways as well as discuss the potential ... These findings may be relevant to IL-21s potential clinical implications and applications. ... IL-21 activates both the Raf-ERK-MAPK and the Jak/STAT signaling pathways. These pathways mediate some of the effects of IL-21 ...
1998) Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the ... 1991) Receptors for interleukin-1 (α and β) in mouse brain: mapping and neuronal localization in hippocampus. Neuroscience 43: ... 1997) Type 2 interleukin-1 receptor mRNA is induced by kainic acid in the rat brain. Mol Brain Res 50:237-245. ... 1998) Kainic acid induced expression of interleukin-1 receptor antagonist mRNA in the rat brain. Mol Brain Res 58:195-208. ...
... areceptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces thegrowth promoting ... The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type Icytokine receptors, ... Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved ... IL21R; interleukin 21 receptor; interleukin-21 receptor; CD360; IL-21R; IL-21 receptor; novel interleukin receptor; NILR; ...
Methodology: The B cell receptor (BCR), CD40, B-cell activating factor (BAFF)-receptors and Interleukin (IL) 21 receptor and ... only 283 and 129 genes were modulated by lipopolysaccharide or BAFF receptor stimulation, respectively. Interestingly, genes ... Toll like receptor 4 (TLR4) were stimulated in human transformed germinal centre B cells by treatment with anti IgM F(ab)2- ...
Since interleukin (IL)-21 plays an important role in inducing and maintaining immune-mediated chronic inflammatory processes ... Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents ... Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function ... Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses ...
C-X-C chemokine receptor 2 (CXCR2) is a chemotactic receptor that is critical in neutrophil mobilization from bone marrow to ... We have previously reported that a single nucleotide polymorphism (SNP) in leptin receptor (LEPR), present in up to 50% of ... We have previously reported that a single nucleotide polymorphism (SNP) in leptin receptor (LEPR), present in up to 50% of ... is a chemotactic receptor that is critical in neutrophil mobilization from bone marrow to blood and tissue sites. ...
Thalidomide and anti-interleukin (IL)-6 receptor antibody treatment have shown efficacy in small series of SoJIA patients.4 5 ... Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult ... Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult ... Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile ...
The secreted form of the interleukin-1 receptor antagonist (IL-1Ra) is an acute-phase protein intervening in the ... The interleukin-1 receptor antagonist (IL-1Ra) is a member of the interleukin (IL)-1 family that binds to IL-1 receptors ... interleukin; IL-1Ra, interleukin-1 receptor antagonist; LPS, lipopolysaccharide; PMA, phorbol myristate acetate; PPAR-γ, ... Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor ...
... the IL-2 receptor beta chain and is capable of transducing signals through its dimerization with the common cytokine receptor ... Interleukin-21 (IL-21) is a type I cytokine that modulates functions of T, B, natural killer (NK), and myeloid cells. The IL-21 ... Interleukin-21 (IL-21) is a type I cytokine that modulates functions of T, B, natural killer (NK), and myeloid cells. The IL-21 ... receptor (IL-21R) is closely related to the IL-2 receptor beta chain and is capable of transducing signals through its ...
α1-Adrenergic Receptor Stimulates Interleukin-6 Expression and Secretion through Both mRNA Stability and Transcriptional ... α1-Adrenergic Receptor Stimulates Interleukin-6 Expression and Secretion through Both mRNA Stability and Transcriptional ... α1-Adrenergic Receptor Stimulates Interleukin-6 Expression and Secretion through Both mRNA Stability and Transcriptional ... α1-Adrenergic Receptor Stimulates Interleukin-6 Expression and Secretion through Both mRNA Stability and Transcriptional ...
It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has ... This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster ... The protein encoded by this gene belongs to the cytokine receptor family. ... Interleukin 10 receptor beta; Interleukin-10 receptor subunit 2; OTTHUMP00000067678; cytokine receptor class-II CRF2-4; ...
Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta ... Association of interleukin-23 receptor variants with ankylosing spondylitis. Arthritis Rheum. 2008 Apr. 58(4):1020-5. [QxMD ... The interleukin-23/interleukin-17 axis in spondyloarthritis. Curr Opin Rheumatol. 2008 Jul. 20(4):392-7. [QxMD MEDLINE Link]. ... Interleukin-17 Inhibitors. Class Summary. Various interleukins play a role in inflammatory processes. ...
... single domain nanobody fusion protein that acts by targeting interleukin 21 receptor. It is administered through intravenous ... The drug candidate is a recombinant IL-21 and anti human serum albumin (HAS) ...
Results Plasma fatty acid-binding protein 4, interleukin-1 receptor antagonist, interleukin-6 and leptin were negatively ... Results Plasma fatty acid-binding protein 4, interleukin-1 receptor antagonist, interleukin-6 and leptin were negatively ... interleukin-1 receptor antagonist, interleukin-6 and leptin were negatively associated with FVC and agouti-related protein, ... interleukin-1 receptor antagonist, interleukin-6 and leptin were negatively associated with FVC and agouti-related protein, ...
Target Pipeline List of Interleukin-2 Receptor Agonists as of August 2018 ... Interleukin-2 Receptor Agonists - Target Pipeline List 08/2018. Target: Interleukin-2 receptor; IL-2R; IL-2Ralpha; CD25; IL- ... Interleukin-2 Receptor Agonists - Target Pipeline List 08/2018. Publisher: La Merie Publishing ×. La Merie Publishing. ... CAR-M Industry Landscape Analysis: Chimeric Antigen Receptor-Macrophage (CAR-M) Stakeholders, Technologies, Pipeline, ...
Signaling by Interleukins (Homo sapiens) * Interleukin-2 family signaling (Homo sapiens) * Interleukin-21 signaling (Homo ... IL21 receptor JAK phosphorylation (Homo sapiens) * IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Homo sapiens) ... IL21 receptor STAT binding (Homo sapiens) * IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Homo sapiens) ... IL21 receptor STAT phosphorylation (Homo sapiens) * IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane ...
Dive into the research topics of Human monocytes express functional receptors for granulocyte colony- stimulating factor that ... Human monocytes express functional receptors for granulocyte colony- stimulating factor that mediate suppression of monokines ...
IL-21 Antibody can be used for Western Blot, ELISA, and other antibody applications. ... also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a ... Interleukin-21 enhances T-helper cell type I signaling and interferon-γ production in Crohns disease. Gastroenterology. 2005; ... Antigenicepitopes of Interleukin-21, related antibodies and their use in medical field. U.S patent application publication. ...
These trials may give new insights into the immunobiology of IL-10 and suggest that the IL-10/IL-10 receptor system may become ... Interleukin-10 and chronic liver disease. World J Gastroenterol 2006; 12(11): 1681-1685 [PMID: 16586534 DOI: 10.3748/wjg.v12. ... Interleukin (IL)-10 is an important immunoregulatory cytokine produced by many cell populations. Numerous investigations ... Mar 21, 2006; 12(11): 1681-1685. Published online Mar 21, 2006. doi: 10.3748/wjg.v12.i11.1681 ...
Sigma-1 receptor agonist, (+)-pentazocine, is neuroprotective in a Brown Norway rat microbead model of glaucoma. Mysona, B. A. ... MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral ... Sigma 1 receptor activation improves retinal structure and function in the RhoP23H/+ mouse model of autosomal dominant ... Role of prostaglandin D2 receptors in the pathogenesis of abdominal aortic aneurysm formation. Weintraub, N. L., Blomkalns, A. ...
Artificial Receptors 27% * Synthetic Biology 24% * Biophysics 24% * Interleukin-1 Receptors 21% ...