FCGR1B - The Full Wiki
Ernst L, van de Winkel J, Chiu I, Anderson C (1992). "Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI ... is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity ... 1] It is more commonly known as Fc-gamma receptor 1 (FcγRI). After binding IgG, CD64 interacts with an accessory chain known as ... "Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human ...http://www.thefullwiki.org/FCGR1B
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate...
Programmed Cell Death 1 Receptor. Protein Binding. Receptors, IgG. T-Lymphocytes, Regulatory ... upregulation of the inhibitory Fc gamma receptor (FcγR) IIb at the tumor site prevented intra-tumoral Treg cell depletion, ...https://repository.icr.ac.uk/handle/internal/635
Fc gamma receptor IIB Summary Report | CureHunter
... highly homologous to other Fc gamma RII receptors but has unique cytoplasmic exons; has been sequenced ... Fc gamma receptor IIB: present in myelomonocytic and lymphocytic cells; ... Cell Surface Receptors: 753*Immunologic Receptors: 8*Fc Receptors: 1309*IgG Receptors: 345*Fc gamma receptor IIB: 35 ... Fc gamma receptor IIB. Subscribe to New Research on Fc gamma receptor IIB ...http://www.curehunter.com/public/keywordSummaryC080571-Fc-gamma-receptor-IIB.do
Coupling of Fcγ Receptor I to Fcγ Receptor IIB by Src Kinase Mediates C-Reactive Protein Impairment of Endothelial Function |...
CRP antagonizes endothelial nitric oxide synthase (eNOS) through processes mediated by the IgG receptor Fcγ receptor IIB (Fc ... Coupling of Fcγ Receptor I to Fcγ Receptor IIB by Src Kinase Mediates C-Reactive Protein Impairment of Endothelial Function. ... Coupling of Fcγ Receptor I to Fcγ Receptor IIB by Src Kinase Mediates C-Reactive Protein Impairment of Endothelial Function ... Coupling of Fcγ Receptor I to Fcγ Receptor IIB by Src Kinase Mediates C-Reactive Protein Impairment of Endothelial Function ...http://circres.ahajournals.org/content/early/2011/09/22/CIRCRESAHA.111.254573
The human low affinity Fcgamma receptors IIa, IIb, and III bind IgG with fast kinetics and distinct thermodynamic properties. -...
All three receptors bind Fc or IgG with similarly low affinities (K(D) approximately 0.6-2.5 microm) and fast kinetics, ... suggesting that FcgammaR-mediated recognition of aggregated IgG and IgG-coated particles or cells is mechanistically similar to ... They bind the Fc portion of IgG, thereby triggering a range of immunological functions. We have used surface plasmon resonance ... Interestingly, the Fc receptors exhibit distinct thermodynamic properties. Whereas the binding of the FcgammaRIIa and ...https://www.neuroscience.ox.ac.uk/publications/15330
Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII). - Oxford Neuroscience
Mouse Ltk- cells transfected with the human Fc gamma R cDNA express a cell-surface receptor that selectively binds human IgG ... The deduced structure is a 35-kD transmembrane protein with homology to the mouse Fc[gamma 2b/gamma 1] receptor amino acid ... including the human c-fms protooncogene/CSF-1 receptor. ... We have cloned and expressed a cDNA encoding a human receptor ... for IgG (Fc gamma R) from the monocyte cell line U937. ... Receptors, Fc, Receptors, IgG, Sequence Homology, Nucleic Acid ...https://www.neuroscience.ox.ac.uk/publications/28336
KEGG PATHWAY: Fc gamma R-mediated phagocytosis - Homo sapiens (human)
After opsonization with antibodies (IgG), foreign extracellular materials are recognized by Fc gamma receptors. Cross-linking ... of Fc gamma receptors initiates a variety of signals mediated by tyrosine phosphorylation of multiple proteins, which lead ...http://www.genome.jp/kegg-bin/show_pathway?133840406410261/hsa04666.args
Interaction with FcγRIIB Is Critical for the Agonistic Activity of Anti-CD40 Monoclonal Antibody | The Journal of Immunology
Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses. Blood 113: 3716- ... activatory/inhibitory receptor binding. CHO. Chinese hamster ovary. DC. dendritic cells. DR5. death receptor 5. IKK. IκB kinase ... Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood 99 ... An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells. Cancer Cell 19: 101-113 ...http://www.jimmunol.org/content/187/4/1754.long
Characteristics and interrelation of two types of immunoglobulin G Fc receptors on human monocytes | Biochemical Society...
FcγR, receptor for the Fc portion of IgG. HR, high-responder ... EA-hIgG, human IgG-sensitized human erythrocytes. EA-mIgGl, ... Characteristics and interrelation of two types of immunoglobulin G Fc receptors on human monocytes. JAN G. J. van de WINKEL, ... Characteristics and interrelation of two types of immunoglobulin G Fc receptors on human monocytes ... Characteristics and interrelation of two types of immunoglobulin G Fc receptors on human monocytes ...http://www.biochemsoctrans.org/content/16/5/734
The Levels of CD16/Fcγ Receptor IIIA on CD14+ CD16+ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia...
... by promoting phagocytosis of IgG-coated uninfected red cells and by allowing the production of tumor necrosis factor alpha (TNF ... Fc gamma receptor IIIA (CD16/FcγRIIIA) on monocytes/macrophages may play an important role in the pathogenesis of severe ... The Levels of CD16/Fcγ Receptor IIIA on CD14+ CD16+ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia ... not much is known about the differential expression of this receptor on monocytes of children with severe malaria and ...http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/41943
'receptors igg' Protocols and Video...
Receptors, IgG: Specific molecular sites on the surface of various cells, including B-lymphocytes and macrophages, that combine ... a high affinity receptor), and Fc gamma Riii (the Cd16 antigen, a low affinity receptor). ... Three subclasses exist: Fc gamma Ri (the Cd64 antigen, a low affinity receptor), Fc gamma Rii (the Cd32 antigen, ...https://www.jove.com/keyword/receptors+igg
Fc fragment of igg receptor iic (gene/pseudogene) - Wikipedia
Fc fragment of IgG receptor IIc (gene/pseudogene) is a protein that in humans is encoded by the FCGR2C gene. This gene encodes ... Fc fragment of IgG receptor IIc (gene/pseudogene)". Retrieved 2017-05-24. Breunis WB, van Mirre E, Bruin M, Geissler J, de Boer ... "Phenotypic variation in IgG receptors by nonclassical FCGR2C alleles". J. Immunol. 188 (3): 1318-24. doi:10.4049/jimmunol. ... Fragment c gamma receptor gene polymorphisms and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, ...https://en.wikipedia.org/wiki/Fc_fragment_of_igg_receptor_iic_(gene/pseudogene)
Immature Neutrophils Mediate Tumor Cell Killing via IgA but Not IgG Fc Receptors | The Journal of Immunology
Immature Neutrophils Mediate Tumor Cell Killing via IgA but Not IgG Fc Receptors. Marielle A. Otten, Esther Rudolph, Michael ... 6. Biology of the High Affinity IgG Receptor: A Tale of a Tail: Thesis ISBN 90-9018813-4 99. Utrecht University, Faculty of ... Binding of IgG to such cells may act as an Ab "sink." In addition, binding of IgG to the inhibitory FcR, FcγRIIb, might lead to ... Clinical significance of IgG Fc receptors and FcγR-directed immunotherapies. Immunol. Today 18:127. ...http://www.jimmunol.org/content/174/9/5472.long
MHC Class I-Related Neonatal Fc Receptor for IgG Is Functionally Expressed in Monocytes, Intestinal Macrophages, and Dendritic...
The neonatal Fc receptor (FcRn) for IgG, an MHC class I-related molecule, functions to transport IgG across polarized ... Blockade of FcRn-mediated IgG binding by IgG Fc fragment. IgG binding assays were performed as described in Fig. 6⇑. For ... Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study ... An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta. Eur. J. Immunol. 26: 1527. ...http://www.jimmunol.org/content/166/5/3266.long
Interleukin-1 alpha, soluble interleukin-2 receptor, and IgG concentrations in cystic fibrosis treated with prednisolone. -...
Interleukin-1 alpha, soluble interleukin-2 receptor, and IgG concentrations in cystic fibrosis treated with prednisolone.. ... soluble interleukin-2 receptor (sIL-2R), and IgG was investigated in 24 children with cystic fibrosis. Prednisolone was ... In the treated group, change in pulmonary function was associated with decreased serum IgG and cytokine concentrations. ... the excessive synthesis of IgG, and airflow obstruction observed in cystic fibrosis patients. ...https://www.ncbi.nlm.nih.gov/pubmed/8067791?dopt=AbstractPlus
Cytokine-induced immune complex binding to the high-affinity IgG receptor, FcγRI, in the presence of monomeric IgG
... DSpace/ ... FcγRI is the sole high-affinity immunoglobulin G (IgG) receptor on leukocytes. Its role in immunity and the clearance of ... as the receptor function may well be hindered by serum IgG. Here, we document immune complex binding by FcγRI to be readily ... Receptors, IgG, Journal Article, Research Support, Non-U.S. Gov't, Journal Article, Research Support, Non-U.S. Gov't ...https://dspace.library.uu.nl/handle/1874/197555
Avian IgY Binds to a Monocyte Receptor with IgG-like Kinetics Despite an IgE-like Structure*
... ... Avian IgY Binds to a Monocyte Receptor with IgG-like Kinetics Despite an IgE-like Structure*. ... but is within the range of mammalian IgG-high affinity receptor interactions (human: Ka ~ 108-109 M-1 mouse: Ka ~ 107-108 M-1. ... The kinetics of IgY binding to its receptor on a chicken monocyte cell line, MQ-NCSU, were measured, the first time that the ...https://gallusimmunotech.com/years/entry/avian-igy-binds-to-a-monocyte-receptor-with-igg-like-kinetics-despite-an-ige-like-structure.html
FCGRT elisa kit | Human Fc fragment of IgG, receptor, transporter, alpha ELISA Kit-NP 001129491.1
... receptor, transporter, alpha ELISA Kit-NP_001129491.1 (MBS937383) product datasheet at MyBioSource, ELISA Kits ... IgG receptor FcRn large subunit p51; FcRn alpha chain; neonatal Fc receptor; neonatal Fc-receptor for Ig; IgG Fc fragment ... Fc fragment of IgG, receptor, transporter, alpha (FCGRT), ELISA Kit. Also Known As Human IgG receptor FcRn large subunit p51, ... IgG receptor FcRn large subunit p51 UniProt Synonym Protein Names IgG Fc fragment receptor transporter alpha chain; Neonatal Fc ...https://www.mybiosource.com/prods/ELISA-Kit/Human/Fc-fragment-of-IgG-receptor-transporter-alpha/FCGRT/datasheet.php?products_id=937383
Functional comparisons of different tumour necrosis factor receptor/IgG fusion proteins. - Nuffield Department of Orthopaedics,...
The fusion proteins differed with respect to TNF receptor type (p55 or p75 TNF receptor), receptor valency (one, two or four ... Thus, this study has identified structural modifications to TNF receptor/IgG fusion proteins which have differing effects on ... receptor domains per molecule), the presence or absence of a CH1 domain in the IgG constant region, and the proportion of the ... The presence or absence of an IgG CH1 domain made no difference in the ability of fusion proteins to neutralize TNF-alpha or ...https://www.ndorms.ox.ac.uk/publications/482008
Muscle acetylcholine receptors complexed with autologous IgG reflect seropositivity but not necessarily in vivo binding |...
Muscle acetylcholine receptors complexed with autologous IgG reflect seropositivity but not necessarily in vivo binding. Masato ... Muscle acetylcholine receptors complexed with autologous IgG reflect seropositivity but not necessarily in vivo binding ... Thus, the finding of IgG complexed to AChR extracted from biopsied muscle does not necessarily reflect in vivo binding but, ... membranous AChR became complexed with IgG. This was so even with a nonmyasthenogenic monoclonal antibody specific for the α- ...http://n.neurology.org/content/42/1/218
Gentaur Molecular :Alpha Dia \ Monoclonal Anti Human GCSF receptor protein IgG, aff pure \ GCSFR14-M
Human GCSF receptor protein IgG, aff pure \ GCSFR14-M for more molecular products just contact us ... Human GCSF receptor protein IgG, aff pure. Related products : Monoclonal Anti_Human GCSF receptor protein IgG, aff pure ... Human GCSF receptor protein IgG, aff pure / Product Detail : GCSFR14-M Monoclonal Anti_Human GCSF receptor protein IgG, aff ... WP1271: Toll-like receptor signaling pathway. WP1284: EPO Receptor Signaling. WP1309: Toll-like receptor signaling pathway. ...http://www.antibody-antibodies.com/product_det.php?id=58738&supplier=search&name=Monoclonal%20Anti_Human%20GCSF%20receptor%20protein%20IgG,%20aff%20pure
The Scaffolding Protein Synapse-Associated Protein 97 Is Required for Enhanced Signaling Through Isotype-Switched IgG Memory B...
Protein Synapse-Associated Protein 97 Is Required for Enhanced Signaling Through Isotype-Switched IgG Memory B Cell Receptors ... A scaffolding protein clusters B cell receptors to enable the rapid, high-titer antibody responses of memory B cells. ... A scaffolding protein clusters B cell receptors to enable the rapid, high-titer antibody responses of memory B cells. ... Protein Synapse-Associated Protein 97 Is Required for Enhanced Signaling Through Isotype-Switched IgG Memory B Cell Receptors ...http://stke.sciencemag.org/content/5/235/ra54.full
MOLECULAR-BASIS OF IGG FC RECEPTOR-III DEFECT IN A PATIENT WITH SYSTEMIC LUPUS-ERYTHEMATOSUS
... ENENKEL B, JUNG D, Frey J (1991) ... MOLECULAR-BASIS OF IGG FC RECEPTOR-III DEFECT IN A PATIENT WITH SYSTEMIC LUPUS-ERYTHEMATOSUS. EUROPEAN JOURNAL OF IMMUNOLOGY, ... "MOLECULAR-BASIS OF IGG FC RECEPTOR-III DEFECT IN A PATIENT WITH SYSTEMIC LUPUS-ERYTHEMATOSUS". EUROPEAN JOURNAL OF IMMUNOLOGY ... ENENKEL B, JUNG D, Frey J. MOLECULAR-BASIS OF IGG FC RECEPTOR-III DEFECT IN A PATIENT WITH SYSTEMIC LUPUS-ERYTHEMATOSUS. ...https://pub.uni-bielefeld.de/publication/1650139
Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis
... Tomonari Kasai,1 Keisuke ... The cells were stained with anti-human IgG antibody labeled with FITC, anti-EEA1 antibody and anti-rabbit IgG antibody labeled ... Bars = 10 μm. (b) and (c) A172 cells were treated with CTX-Fc-BNCs, human IgG-BNCs, or M-CTX-Fc for 1 h at 4°C or 37°C. After ... A172 cells were treated with CTX-Fc-BNCs or human IgG-BNCs in the presence of 100 nM CPZ or 5 mM MβCD at 37°C for 1 h, followed ...https://www.hindawi.com/journals/jdd/2012/975763/
Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes |...
IgGs and proteolytic enzymes) and, to estimate false discovery rates (FDR), 5993 randomized sequences for each non‐redundant ... containing complexes associate with estrogen receptor alpha. Nucleic Acids Res 30: 2508-2514. ... which also detects the IgG tag in the TAP tag, allowing for simultaneous visualization of both the tag and the interacting ...http://msb.embopress.org/content/7/1/503