Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor ... Control of fibronectin receptor expression by fibronectin: antisense fibronectin RNA downmodulates the induction of fibronectin ... Perez, R.L.; Staton, G.W.Jr; Roman, J. 1991: Fibronectin fibronectin receptor and transforming growth factor beta in murine ... because fibronectin matrix assembly may assembly may involve the fibronectin cell adhesive receptor complex, increased receptor ...
PCR was performed to detect the expression of the protease-activated receptors (PARs) in MSCs. After thrombin treatment, the ... Fibronectin (FN) is commonly used in the development of serum-free media for the expansion of mesenchymal stem cells (MSCs). ... Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated ... Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated ...
Receptors, Cell Surface / metabolism * Structure-Activity Relationship * Transcription, Genetic Substances * Fibronectins * ... Fibronectins Sci Am. 1986 Jun;254(6):42-51. doi: 10.1038/scientificamerican0686-42. ...
Fibronectin receptors from Streptococcus dysgalactiae and Staphylococcus aureus. Involvement of conserved residues in ligand ... Fibronectin receptors from Streptococcus dysgalactiae and Staphylococcus aureus. Involvement of conserved residues in ligand ... Fibronectin receptors from Streptococcus dysgalactiae and Staphylococcus aureus. Involvement of conserved residues in ligand ... title = "Fibronectin receptors from Streptococcus dysgalactiae and Staphylococcus aureus. Involvement of conserved residues in ...
Horwitz A, Duggan K, Buck C, Beckerle MC, Burridge K (1986). "Interaction of plasma membrane fibronectin receptor with talin--a ... LaFlamme SE, Akiyama SK, Yamada KM (Apr 1992). "Regulation of fibronectin receptor distribution". The Journal of Cell Biology. ... "Entrez Gene: ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)". Hynes RO (Apr ... Integrin receptors exist as heterodimers, and greater than 20 different integrin heterodimeric receptors have been described. ...
Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III. * NM_001278723.3 → NP_001265652.2 interleukin-20 receptor ... Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III. * NM_001278724.4 → NP_001265653.2 interleukin-20 receptor ... Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III. * NM_014432.4 → NP_055247.4 interleukin-20 receptor ... interleukin-20 receptor subunit alpha. Names. class II cytokine receptor ZCYTOR7. cytokine receptor family 2 member 8. ...
The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes ... The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes ... The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes ... located in the eighth fibronectin type III domain of PTPRJ. A deletion in the eighth fibronectin domain of PTPRJ impairs its ...
IPR003961 Fibronectin type III. IPR036116 Fibronectin type III superfamily. IPR008979 Galactose-binding-like domain superfamily ... IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like. IPR001426 Tyrosine-protein kinase, receptor class V, conserved ... J:17817 Sajjadi FG, et al., Identification of a new eph-related receptor tyrosine kinase gene from mouse and chicken that is ... IPR034266 Ephrin type-A receptor 3, ligand binding domain. ... regulated and encodes at least two forms of the receptor. New ...
1) The first cluster is around fibronectin. Fibronectin is induced by aldosterone in peripheral tissue [67], whereas with the ... Aldosterone, Endothelin, 5-HT3 receptor, 5-HT7 receptor, FKBP5, NMDA, Mineralocorticoid receptor, Nucleus of the solitary tract ... Polymorphism of the 5-HT2A receptor and FKBP5 have been confirmed as well [53,54]. The 5-HT2A receptor is related to the ... Part of the reason for this is that the receptors for aldosterone, the mineralocorticoid receptors (MR), were thought to be ...
Mouse monoclonal Eph receptor A2 antibody [Ka-5H5]. Validated in Flow Cyt, ICC/IF, cELISA and tested in Human. ... Ephrin receptor subfamily.. Contains 2 fibronectin type-III domains.. Contains 1 protein kinase domain.. Contains 1 SAM ( ... Anti-Eph receptor A2 antibody [Ka-5H5]. See all Eph receptor A2 primary antibodies. ... Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Plays an important role in angiogenesis and ...
C and D) GRK2 downmodulation enhances the PI3K-dependent directed cell migration of ECs in response to fibronectin (FN) and S1P ... Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances α1D-adrenergic receptor constriction. Am J ... The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism ... B and C) Proper signaling of Smads downstream of ALK1 and ALK5 receptor activation depends on GRK2 expression. (B) Grk2+/- ...
Timeline for Protein Interleukin-2 receptor beta chain from b.1.2.1: Fibronectin type III: *Protein Interleukin-2 receptor beta ... Fibronectin type III appears in SCOPe 2.01. *Protein Interleukin-2 receptor beta chain from b.1.2.1: Fibronectin type III ... Superfamily b.1.2: Fibronectin type III [49265] (1 family) *. Family b.1.2.1: Fibronectin type III [49266] (44 proteins). Pfam ... More info for Protein Interleukin-2 receptor beta chain from b.1.2.1: Fibronectin type III. ...
Receptors, Metabotropic Glutamate * extracellular leucine-rich repeat fibronectin containing 1 protein, mouse ... with postsynaptic mGluR6 receptors. We show this coordination requires an extracellular protein, α2δ4, which complexes with CaV ...
CD49 antigen-like family member E; CD49e antigen; CD49e; Fibronectin receptor subunit alpha; fibronectin receptor, alpha ... fibronectin receptor, alpha polypeptide); ITGA5; very late activation protein 5, alpha subunit; VLA-5 alpha; VLA-5 ... Integrin alpha 5 beta 1 is a receptor for fibronectin and neural adhesion molecule L1. ...
CD29 antigen; CD29; Fibronectin receptor subunit beta; FNRBVLAB; GPIIA; Integrin beta 1; integrin beta-1; integrin VLA-4 beta ... fibronectin receptor, beta polypeptide, antigen CD29 includesMDF2, MSK12); ITGB1; MDF2; MSK12; very late activation protein, ...
Ligand/Receptor Fibronectin, vitronectin, vWF Cell Type Fibroblasts, Megakaryocytes, Osteoclasts, Platelets Biology Area ... fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, ...
... monoclonal antibody specifically binds to the α5 chain of the integrin α5β1 fibronectin receptor (CD49e/CD29, VLA-5) on ... monoclonal antibody specifically binds to the α5 chain of the integrin α5β1 fibronectin receptor (CD49e/CD29, VLA-5) on ... Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins. ... The 5H10-27 (MFR5) monoclonal antibody specifically binds to the α5 chain of the integrin α5β1 fibronectin receptor (CD49e/CD29 ...
Integrin, β1 (fibronectin receptor, β polypeptide). Promotes human lung cancer cell invasion and metastasis in vitro and in ... Fibronectin 1. Promotes pulmonary metastasis of human fibrosarcoma HT1080 cells in nude mice. Upregulation is associated with ... Ying L, Lau A, Alvira CM, et al: LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective ... efficacy of metabolised pycnogenol and downregulation of several genes encoding for cell adhesion proteins such as fibronectin ...
In turn, the activated cells secrete a variety of substances, including cytokines and their soluble receptors and enzymes and ... These substances lead to changes in the extracellular matrix compounds, including fibronectin; proteoglycans; and collagen ...
Ligand/Receptor Hyaluronan, MIP-1β, fibronectin, collagen Cell Type B cells, Endothelial cells, Epithelial cells, Leukocytes, ...
Expression and function of the chemokine receptor CCR7 in thyroid carcinomas. J Endocrinol. 2006;191:229-38 ... 4A). Hub genes fibronectin (FN1; degree = 22), cadherin (CDH2; degree = 13), alpha-1-antitrypsin (SERPINA1; degree = 11), and ... G protein-coupled receptor signaling pathway. IBA. UniProtKB:P13501. PMID:21873635. cellular response to interleukin-1. IBA. ... CCR chemokine receptor binding. IBA. UniProtKB:Q9Y258. PMID:21873635. lymphocyte chemotaxis. IBA. UniProtKB:Q9Y258. PMID: ...
As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of ... Receptors, Cytoadhesin [D12.776.543.750.705.408.460]. *Platelet Glycoprotein GPIIb-IIIa Complex [D12.776.543.750.705.408. ... Sex-specific platelet activation through protease-activated receptor-1 in patients undergoing cardiac catheterization. ... Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and ...
ECM components (i.e., fibronectin or collagens) directly interact with membrane receptors (i.e., integrins), particularly, by ... CCR2 CC Chemokine receptor 2, the CCL2 receptor), inflammatory cytokine production (TNFα), and pro-inflammatory transcriptional ... For example, inactive pro-TGF-β interacts with fibronectin [22] and thrombospondin [23]. In the context of ECM remodeling, MMP- ... Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytes. Cell. 1983;35:657-66. ...
It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing ... The complex, dynamic process of FN matrix assembly is a cell-mediated process that involves interactions between receptors on ... Fibronectin (FN) is an abundant ECM protein secreted by cells as a soluble dimer and assembled into an insoluble fibrillar ... A top view displays substrate FN (A) cellular fibronectin (B) DAPI (C) and a merged image (D) of all structures. Also a merged ...
... rather than by the receptor-mediated adhesion through serum-derived proteins adsorbed on the PPs. ... The extracellular parts of these receptors bind the ECM proteins (e.g., vitronectin, fibronectin), adsorbed on the studied ... in fibronectin crosslinking46. Tissue transglutaminase co-localizes with beta1-integrin adhesion receptors47, and it has a ... It was attributed to binding of cells to glycated collagen through αvβ3 integrin adhesion receptors instead of the α2β1 ...
A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I ... A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I ...
Monolayers exposed to histamine for 30 min released interleukin-6 and fibronectin in the apical direction, in a dose-dependent ... the effect was inhibited by the H1 receptor antagonist diphenhyramine, suggesting that BEAS cells retain functioning histamine ... receptors. BEAS cells were grown to confluence on microporous, collagen-coated filters, allowing measurement of vectorial ...
Role of fibronectin in the prevention of adherence of Pseudomonas aeruginosa to buccal cells. J Infect Dis 1981;143:784-90. * ... Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surfaces. J Infect Dis 1981; ... Fibronectin: a brief overview of its structure, function, and physiology. Rev Infect Dis 1987;9:S317-21. * Niederman MS, ... Adherence of Streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial ...
UniProtKB description: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and ... Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation (PubMed:34089617). ... Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for ... actin (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Fibronectins are involved in cell adhesion, cell ...
... the alternative that GPR56 could affect adhesion by regulating expression of integrin receptors for laminin-1 and fibronectin ... an orphan receptor of the poorly understood adhesion G-protein-coupled receptor (GPCR) family (Bjarnadóttir et al., 2007). BFPP ... 2008) Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J ... Granule cells from the rostral region of Gpr56−/− cerebella have defects in adhesion to fibronectin and laminin-1. Freshly ...