*  Plus it
However, in other tissues, these nuclear receptors form an interacting, regulatory network in which cross-talk among receptors ... protecting cytoplasmic function by sequestering xenobiotics in vesicles, and possibly limiting nuclear exposure to xenobiotics. ... These cytokines down-regulate transporter expression, possibly by suppressing nuclear receptors (e.g., PXR, hepatocyte nuclear ... Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Mol Endocrinol 17 ...
  http://pharmrev.aspetjournals.org/content/60/2/196
*  Constitutive androstane receptor - Wikipedia
The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, group I, member 3 is a protein that in ... Phosphorylated CAR forms a multiprotein complex with the heat shock protein 90 (hsp90) and the cytoplasmic CAR retention ... CAR is a member of the nuclear receptor superfamily and along with pregnane X receptor (PXR) functions as a sensor of ... "An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors". Science. 272 ( ...
  https://en.wikipedia.org/wiki/Constitutive_androstane_receptor
*  Browsing UT Southwestern Electronic Theses and Dissertations by Subject "Receptors, Cytoplasmic and Nuclear"
Liver receptor homolog-1 (LRH-1), an orphan nuclear receptor, and farnesoid X receptor (FXR), a bile acid receptor, are both ... Browsing UT Southwestern Electronic Theses and Dissertations by Subject "Receptors, Cytoplasmic and Nuclear". 0-9. A. B. C. D. ... They regulate biological events in mammals by acting on nuclear receptors and membrane-bound receptors. ... ... Nuclear Receptors in Lung Cancer  Jeong, Yangsik (2007-05-22) Lung Cancer is a fatal disease with new diagnoses of more than ...
  http://repositories.tdl.org/utswmed-ir/handle/2152.5/186/browse?value=Receptors%2C+Cytoplasmic+and+Nuclear&type=subject
*  Interplay Between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediate Castration Resistance | Molecular Cancer...
Interplay Between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediate Castration Resistance. Yan Dong, Yang Zhan ... Interplay Between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediate Castration Resistance ... Interplay Between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediate Castration Resistance ... Interplay Between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediate Castration Resistance ...
  http://mcr.aacrjournals.org/content/early/2016/09/24/1541-7786.MCR-16-0236.article-info
*  Identification and characterization of anti-osteoclastogenic peptides derived from the cytoplasmic tail of receptor activator...
Osteoclastogenesis depends on receptor activator of nuclear factor kappa B (RANK) signaling mediated by TRAF6. We previously ... and characterization of anti-osteoclastogenic peptides derived from the cytoplasmic tail of receptor activator of nuclear ... and characterization of anti-osteoclastogenic peptides derived from the cytoplasmic tail of receptor activator of nuclear ... Following the cloning of the classical opioid receptors (μ, δ and κ), the opioid receptor like-1 (ORL-1) was identified as a ...
  http://connection.ebscohost.com/c/articles/79824426/identification-characterization-anti-osteoclastogenic-peptides-derived-from-cytoplasmic-tail-receptor-activator-nuclear-factor-kappa-b
*  Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of...
Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of ... Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of ... Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris--ciliary body of the rabbit. ... Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of ...
  http://iovs.arvojournals.org/article.aspx?articleid=2159419
*  British Library EThOS: The interaction of environmentally relevant pollutants with nuclear hormone receptors of European...
Receptors, Cytoplasmic and Nuclear ; Cell Communication ; Nuclear receptors (Biochemistry) ... Receptors, Cytoplasmic and Nuclear ; Cell Communication ; Nuclear receptors (Biochemistry) ... Nuclear hormone receptors (NHRs) are ligand-activated transcriptions factors which transduce the effects of various hormones as ... The interaction of environmentally relevant pollutants with nuclear hormone receptors of European flounder (Platichthys flesus ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549825
*  Chapter 4 Cell Membrane Flashcards by Hailey Haas | Brainscape
Cytoplasmic or nuclear receptors 43 GnRH, TRH, GHRH, CRH, Ang II, ADH (V1), oxytocin, alpha adrenergic agonists a stim by ... Lipophilic and able to go straight through plasma, bind to receptor in cytoplasm, binds to DNA in nucleus, attracts RNA ... Many ligands bind to receptors associated with membrane bound __ ___ to initiate transduction pathways. They react with other ...
  https://www.brainscape.com/flashcards/chapter-4-cell-membrane-5373703/packs/8077886
*  Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR...
Bile acid synthesis is under negative feedback control through activation of the nuclear receptor farnesoid X receptor ( ... 0/Anti-Bacterial Agents; 0/Bile Acids and Salts; 0/Receptors, Cytoplasmic and Nuclear; 0/farnesoid X-activated receptor; 0/ ... Receptors, Cytoplasmic and Nuclear / antagonists & inhibitors*, metabolism. Taurocholic Acid / analogs & derivatives*, ... Bile acid synthesis is under negative feedback control through activation of the nuclear receptor farnesoid X receptor (FXR) in ...
  http://www.biomedsearch.com/nih/Gut-Microbiota-Regulates-Bile-Acid/23395169.html
*  Impact of the Pro12Ala polymorphism of the PPAR-gamma2 gene on serum triacylglycerol response to n-3 fatty acid supplementation.
... present study was to investigate the influence of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor- ... 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Fatty Acids, Omega-3; 0/Fish Oils; 0/Plant Oils; 0/Receptors, Cytoplasmic and Nuclear ... present study was to investigate the influence of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor- ...
  http://www.biomedsearch.com/nih/Impact-Pro12Ala-polymorphism-PPAR-gamma2/12765846.html
*  Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome, and rhizomelic chondrodysplasia...
Receptors, Cytoplasmic and Nuclear / genetics, metabolism. Transfection. Zellweger Syndrome / genetics, metabolism, pathology* ... 0/Glycosylphosphatidylinositols; 0/Membrane Proteins; 0/PEX16 protein, human; 0/Receptors, Cytoplasmic and Nuclear; 0/ ... peroxisomal targeting signal 2 receptor; 157153-79-2/PEX19 protein, human; EC 2.3.-/Acyltransferases; EC 2.3.1.42/glycerone- ...
  http://www.biomedsearch.com/nih/Defective-lipid-remodeling-GPI-anchors/22253471.html
*  Benign mesenchymal tumours and tumour-like lesions in end-stage renal disease.
Receptors, Cytoplasmic and Nuclear / metabolism. Retrospective Studies. Tumor Markers, Biological / metabolism. Young Adult. ... 0/Antigens, CD31; 0/FLII protein, human; 0/Microfilament Proteins; 0/Receptors, Cytoplasmic and Nuclear; 0/Tumor Markers, ...
  http://www.biomedsearch.com/nih/Benign-mesenchymal-tumours-tumour-like/23020314.html
*  Methylpiperidinopyrazole - Wikipedia
Cytoplasmic and Nuclear Receptors-Advances in Research and Application: 2012 Edition. ScholarlyEditions. 26 December 2012. pp. ... Receptor/signaling modulators. Estrogens and antiestrogens. Androgen receptor modulators. Progesterone receptor modulators. ... Eckhard Ottow; Hilmar Weinmann (8 September 2008). Nuclear Receptors as Drug Targets. John Wiley & Sons. pp. 50-. ISBN 978-3- ... Synthesis of Non-steroidal Estrogen Receptor Proteolysis Targeting Chimeric Molecules (PROTACS). ProQuest. 2008. pp. 11-. ISBN ...
  https://en.wikipedia.org/wiki/Methylpiperidinopyrazole
*  The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains - Lancaster EPrints
Receptors, Cytoplasmic and Nuclear ; Solubility ; Tumor Cells, Cultured ; Type C Phospholipases. ... 5-Trisphosphate Receptors ; Membrane Proteins ; Mice ; Mice, Inbred C3H ; Neuroblastoma ; Phosphatidylinositol Diacylglycerol- ... Although the inositol trisphosphate receptor was highly enriched in this detergent-insoluble fraction, neither amyloid ...
  http://eprints.lancs.ac.uk/51855/
*  Retrograde/antegrade liver perfusion for studies on hep | Open-i
Hepatotoxicity, as well as hepatic metabolism, is controlled by a set of nuclear receptors (including PXR, CAR, HNF-4α, FXR, ... Hepatotoxicity, as well as hepatic metabolism, is controlled by a set of nuclear receptors (including PXR, CAR, HNF-4α, FXR, ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3753504_204_2013_1078_Fig10_HTML&req=4
*  Regulation of LXR target mRNA levels after chronic admi | Open-i
Receptors, Cytoplasmic and Nuclear/agonists*/genetics/metabolism. Minor. *ATP Binding Cassette Transporter 1 ... Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism. LXR agonists have been shown to limit ... Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism. LXR agonists have been shown to limit ... We report on the antiatherogenic properties of the steroidal liver X receptor agonist N,N-dimethyl-3beta-hydroxy-cholenamide ( ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2636920_JLR502312f8&req=4
*  Reproductive Molecules Flashcards by Danielle Hilton | Brainscape
Small and lipophilic so can pass through by simple diffusion to bind to nuclear or cytoplasmic receptor ... LH and hCG, therefore they can bind to the same receptors as they both have the same sequence of amino acids in their beta ... Bind to a G-protein coupled receptor with large extracellular domains which bind to the hormone ... oestradiol stimulates LH receptors on granulosa cells --> enables response to LH surge --> ovulation ...
  https://www.brainscape.com/flashcards/reproductive-molecules-4969391/packs/7361260
*  BIO101: Cell-Cell Interactions - Scientific American Blog Network
Once inside the cell, they bind cytoplasmic or nuclear receptors. The hormone-receptors complex enters the nucleus and binds to ... There are three types of cell surface receptors: membrane enzymes, ion channels, and transmembrane receptors. ... The action of nuclear receptors is slow, as it takes some hours for the whole process to occur. The effect is long-lasting (or ... G protein-linked receptors are seven-pass transmembrane proteins. This means that the polypeptide chain traverses the membrane ...
  https://blogs.scientificamerican.com/a-blog-around-the-clock/bio101-cell-cell-interactions/
*  adult pleomorphic rhabdomyosarcoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Receptors, Cytoplasmic and Nuclear / metabolism. *MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma. ... high nuclear/cytoplasmic ratios and pleomorphic nuclei with irregular nuclear contours; uniform, hyperchromatic chromatin; and ... Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptors, Platelet-Derived Growth Factor; EC 2.7.10.1 / Receptors, Vascular ... high nuclear-to-cytoplasmic ratio, marked increase in mitotic activity frequently with atypical mitoses, tumor necrosis, and ...
  http://www.bmlsearch.com/?kwr=adult+pleomorphic+rhabdomyosarcoma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Proposed model for the regulation of CAR by the ubiquit | Open-i
Proposed model for the regulation of CAR by the ubiquitin-proteasome system.An equilibrium between a stable CAR cytoplasmic ... Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system. ... The elevation of cytoplasmic CAR protein with MG132 correlated with an increase of HSP70, and to a lesser extent HSP60. Both ... Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4008524_pone.0096092.g007&req=4
*  "A rhythmic Ror" by Patrick Emery and Steven M. Reppert
Nuclear Receptor Subfamily 1, Group F, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Trans-Activators ...
  https://escholarship.umassmed.edu/neurobiology_pp/76/
*  The expression of FXR in ConA-induced hepatitis. (A) Th | Open-i
Receptors, Cytoplasmic and Nuclear/agonists*/genetics/immunology. Minor. *Alanine Transaminase/blood. *Animals ... The present study assessed the hepatoprotective and antiapoptotic role of farnesoid X receptor (FXR) in AIH. a mouse model of ... The present study assessed the hepatoprotective and antiapoptotic role of farnesoid X receptor (FXR) in AIH. a mouse model of ... CDCA, chenodeoxycholic acid; ConA, concanavalin A; FXR, farnesoid receptor X; PBS, phosphate-buffered saline. Mentions: Hepatic ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4581797_MMR-12-04-5821-g00&req=4
*  BIO101: Cell-Cell Interactions | A Blog Around The Clock
Once inside the cell, they bind cytoplasmic or nuclear receptors. The hormone-receptors complex enters the nucleus and binds to ... There are three types of cell surface receptors: membrane enzymes, ion channels, and transmembrane receptors.. When a signaling ... The action of nuclear receptors is slow, as it takes some hours for the whole process to occur. The effect is long-lasting (or ... G protein-linked receptors are seven-pass transmembrane proteins. This means that the polypeptide chain traverses the membrane ...
  https://blog.coturnix.org/2010/08/10/bio101-cell-cell-interactions/
*  Histo Final Flashcards - Cram.com
Cytoplasmic receptor = nuclear binding protein What is the hypophysis? The pituitary gland. ?Major regulator of the endocrine ... Prominent sER - cytoplasmic membranous structure containing the enzymes to process & modify cholesterol.. do not store steroids ... To own cell receptor (autocrine). Through neurons associated with capillaries that carry neural hormones (eg vasopressin & ... membrane receptor. second messanger (eg cAMP). signal transduction (eg kinase cascade). transcription factors. (membrane ...
  http://www.cram.com/flashcards/histo-final-2006793
*  "Bone loss in inflammatory arthritis: mechanisms and treatment strategi" by Nicole C. Walsh and Ellen M. Gravallese
The RANK/RANKL (receptor activator of nuclear factor-kappaB and RANK ligand) pathway has been shown to be essential for ... Arthritis, Rheumatoid; Bone Resorption; Glycoproteins; Humans; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, ... The RANK/RANKL (receptor activator of nuclear factor-kappaB and RANK ligand) pathway has been shown to be essential for ...
  https://escholarship.umassmed.edu/rheumatology_pubs/63/