... consisting of membrane-bound Ig and disulfide-linked heterodimers of Ig alpha/beta. Studies of Ig alpha or Ig beta have shown ... The response of a B cell to antigen is dependent on the surface expression of a clonotypic B-cell receptor complex (BCR) ... B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta Blood. 1997 Mar 1;89(5):1513-20. ... The response of a B cell to antigen is dependent on the surface expression of a clonotypic B-cell receptor complex (BCR) ...

Receptors, Antigen, T-Cell, alpha-beta*Receptors, Antigen, T-Cell, alpha-beta ... Antigen, T-Cell, alpha-beta" by people in UAMS Profiles by year, and whether "Receptors, Antigen, T-Cell, alpha-beta" was a ... Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]. *Receptors, Antigen, T-Cell, alpha-beta [D12.776.543.750.705.816. ... Antigen T Cell Receptor, beta Chain*Antigen T Cell Receptor, beta Chain ...

1992). "Asymmetric selection of T cell antigen receptor alpha- and beta-chains in HLA-B27 alloreactivity". J. Immunol. 148 (11 ... Olfactory receptor 6C4 is a protein that in humans is encoded by the OR6C4 gene. Olfactory receptors interact with odorant ... The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding- ... The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and ...

Expressed antigens include SSA/Ro, SSB/La, alpha-fodrin and beta-fodrin, and cholinergic muscarinic receptors. [13] Dendritic ... These cells are primarily CD4 T cells (75%) and memory cells, with 10% B cells and immunoglobulin-secreting plasma cells. ... Damage and/or cell death due to viral infection or other causes may provide triggering antigens to Toll-like receptors in or on ... Alpha Omega Alpha, American College of Physicians, American College of Rheumatology, American Medical Association, Phi Beta ...

Thus, administration of flagellin, and perhaps other pathobiont antigens, may confer some protection against chronic ... Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature 360, 225-231 ... CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 ... Chassaing, B., Ley, R. E. & Gewirtz, A. T. Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota ...

This study investigated the link between GM and the intrahepatic T cell receptor (TCR) immune repertoire (IR), and whether GM ... Furthermore, GM modulated hepatic stellate cell (HSC) activation via TCR IR-mediated intrahepatic immune milieu. Our study ... Furthermore, GM modulated hepatic stellate cell (HSC) activation via TCR IR-mediated intrahepatic immune milieu. Our study ... This study investigated the link between GM and the intrahepatic T cell receptor (TCR) immune repertoire (IR), and whether GM ...

T-lymphocytes receptors, antigen, T-cell, alpha-beta, histocompatibility antigens class II. Dr. Kappler has spent the last 10 ... Diabetes mellitus Type 1, insulin, autoantigens, antigen T-cell receptors, programmed cell death 1 receptor. Dr. Michels ... T-lymphocytes, antigen-presenting cells, myeloid cells, cell communication, cell movement, autoantigens, in vivo imaging. The ... B-lymphocytes receptors, antigen, B-cell, clonal anergy, signal transduction receptors, IgC. The primary goals of Dr. Cambiers ...

These HDI-responsive T cells expressed unique oligoclonal gamma/delta rather than alpha/beta T-cell receptors, with ... DNA sequence analysis of T-cell receptors was used to further define clonal populations of HDI-responsive T cells. HDI antigen ... control antigens lead to increased proliferation of specific cell types, CD3+CD4-CD8(dim) and/or CD3+CD4-CD8- cells, from HDI- ... including the cell types involved and the form of the chemical that acts as an antigen. The purpose of this investigation was ...

Murine class I major histocompatibility complex H-2 Db in complex with LCMV-derived GP33 altered peptide V3P and T-cell ... H-2 class I histocompatibility antigen, D-B alpha chain: A. Beta-2-microglobulin: B. Alpha chain of murine P14 T cell receptor ... class I major histocompatibility complex H-2 Db in complex with LCMV-derived GP33 altered peptide V3P and T-cell receptor P14 ...

Killer cell lectin-like receptor, subfamily A member 1) which belongs to the C-type lectin superfamily. Ly-49A is comprised of ... Killer cell lectin-like receptor, subfamily A member 1) which belongs to the C-type lectin superfamily. Ly-49A is comprised of ... MHC Class I ligand-bound Ly-49A can negatively regulate NK-cell cytolytic activity via tyrosine phosphorylation of its ITIM.,/ ... MHC Class I ligand-bound Ly-49A can negatively regulate NK-cell cytolytic activity via tyrosine phosphorylation of its ITIM.,/ ...

... encodes for a 397-amino acid receptor that has an amino terminus with no significant homology to the already reported alpha- ... which we have termed the CRF2gamma receptor. The CRF2gamma cDNA ... We report the discovery of a new CRF2 receptor splice isoform ... and beta-termini. When expressed in 293-EBNA (Epstein-Barr nuclear antigen) cells, the CRF2gamma receptor responds in a dose- ... We report the discovery of a new CRF2 receptor splice isoform found in human brain, which we have termed the CRF2gamma receptor ...

Antigen-stimulated dissociation of BCR mIg from Ig-alpha/Ig-beta: implications for receptor desensitization. Immunity. 1999 Feb ... B cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activation. J Immunol. 1997 Jul 1; ... subunits of the B cell antigen receptor (BCR) become dissociated rendering the receptor incompetent to transduce activating ... is a transmembrane protein found exclusively in B cells that is the transducer component of B-cell receptor (BCR), generating a ...

... novel gene editing systems were used to disrupt the T cell receptor alpha-chain constant region and the T cell receptor beta- ... Beta-2 microglobulin was edited in 95 percent of T cells. A chimeric antigen receptor (CAR) construct was also shown to be ... Novel gene editing systems are shown to enable efficient and specific edits in T cells, NK cells, and B cells- ... B cell editing occurred in approximately 80% of target cells with successful transgene integration. Whats more, as these gene ...

HISTOCOMPATIBILITY ANTIGEN. 1j8h. Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen ... CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, ... MHC class II receptors display antigens for recognition by helper T cells (stimulate development of B cell clones) and ... MHC class II receptors display antigens for recognition by helper T cells (stimulate development of B cell clones) and ...

... expression profiles of monocyte-derived dendritic cells (DCs) obtained from peripheral blood mononuclear cells (PBMCs). DCs are ... obtained from peripheral blood mononuclear cells (PBMCs). DCs are known to play a major role in the regulating function of ... cell adhesion signaling pathway, and inflammatory mediator regulation of TRP channels pathway. Conclusions: Our research ... expression profiles of monocyte-derived dendritic cells (DCs) ... Dendritic cells (DCs), which are the most important antigen- ...

Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry ... HLA class I histocompatibility antigen, A-2 alpha chain: A. Beta-2-microglobulin: B. T-CELL RECEPTOR, ALPHA CHAIN: C. ... 1 x SER- LEU- LEU- MET- TRP- ILE- THR- GLN- CYS: Cancer/testis antigen 1B(Non-covalent). SER-LEU-LEU-MET-TRP-ILE-THR-GLN-CYS.1 ... Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry Coordinates. ...

CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, ... Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide, and MHC Class II Molecule, ... AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY. ... Structure of New Antigen Receptor variable domain from sharks. 1ves. Structure of New Antigen Receptor variable domain from ...

CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, ... Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide, and MHC Class II Molecule, ... AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY. ... Structure of New Antigen Receptor variable domain from sharks. 1ves. Structure of New Antigen Receptor variable domain from ...

Interleukin-2-Receptor (IL-2R) is a protein that is expressed on the cell surface of T and B cells upon activation of by ... antigen stimulation. IL-2R is composed of 3 chains, alpha, beta, and gamma. ... sIL-2R are alpha chains of the IL-2R which have been cleaved by protease and released into blood. ... Measuring soluble Interleukin-2 Receptor (sIL-2R) can be useful in the aid-in-diagnosis of Non-Hodgkin lymphoma and ATL (adult ...

... and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an ... important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the ... The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene ... Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell.. ...

Signaling by the B Cell Receptor (BCR) (Homo sapiens) * Antigen activates B Cell Receptor (BCR) leading to generation of second ... LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) (Homo sapiens) * LYN,FYN,BLK [plasma membrane] (Homo ...

DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA; MHC Class II DR; MLRW ... It presents these peptides on the cell surface for recognition by the T cell receptor on CD4+ T cells. This interaction is ... beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from ... FLJ51114; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLADR; HLA-DR; HLA- ...

Human T cell receptor (TCR) is a T cell surface expressed heterodimer of alpha/beta or gamma/delta chains. TCRs recognize ... antigen peptides bound to MHC molecules forming the basis of antigen specific response by T cells (3, 4). ... Human HA1.7 TCR beta chain expressed on transgenic mouse cells. Specificity: Antibody JOVI-3 is specific for the human V beta 3 ... Functional Application: Antibody JOVI-3 is mitogenic for T cells expressing TCR V beta 3. ...

In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both ... T cell receptor delta variable 1 , hDV101S1 Background T cell receptors recognize foreign antigens which have been processed as ... molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one ... the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor ...

U937 Cells. *T-Lymphocyte Subsets. *Receptors, Antigen, T-Cell, alpha-beta. *Peptides ... Testing of T cell-based cancer therapeutics often involves measuring cancer antigen-specific T-cell populations with the ... Using tetramer-based, single-cell sorting and T-cell receptor β (TCRβ) sequencing, we identified recurrent UNC-CDK4-1 tetramer- ... Peptide/MHC tetramer-based sorting of CD8⁺ T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an ...

Receptors, Antigen, T-Cell, alpha-beta. Receptors, Antigen, T-Cell, gamma-delta ... The process of V(D)J recombination assembles T cell receptor (TCR) genes (α,β,γ,δ) from variable (V), ... and is essential for the formation of diverse antigen receptor repertoires on αβ and γδ T lymphocytes. ... The locus encoding the T cell antigen receptor (TCR) α-chain and δ-chain (Tcra-Tcrd) undergoes recombination of its variable- ...

Antigen description The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta ... The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed ... A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential ... Exbio - Research products - Antibodies - CD and related antigens - Anti-Rt TCR alpha/beta FITC ...

Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. Almeida, E.A., Huovila, A.P., Sutherland, A.E., Stephens, L.E ... The detection by the immunofluorescence assay of 10 to 20 times more antigen-positive cells in n-butyrate-treated BC-1 cells ... Immunofluorescence revealed alpha 6 beta 1 and alpha v beta 3 on the plasma membrane [23]. ... Characterization of cross-reacting antigens on the Epstein-Barr virus envelope and plasma membranes of producer cells. Thorley- ...