*  IGHV4-39 - Immunoglobulin heavy variable 4-39 precursor - Homo sapiens (Human) - IGHV4-39 gene & protein
Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains ... In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a ... after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170). ... Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens ( ...
  http://www.uniprot.org/uniprot/P01824
*  Profiling Mouse B-Cell Receptors with SMART Technology
The unique CDR3 sequence in BCRs is critical for dictating antigen specificity. Taken together, the molecular events described ... functioning via B-cell receptors (BCRs) expressed on their surface. Each B cell expresses a different BCR that allows it to ... Profiling Mouse B-Cell Receptors with SMART Technology. *5' RACE-like approach captures complete V(D)J variable regions of BCR ... The SMARTer Mouse BCR IgG H/K/L Profiling Kit is a powerful tool for profiling mouse B-cell receptors. By leveraging SMART ...
  http://www.clontech.com/US/Products/cDNA_Synthesis_and_Library_Construction/NGS_Learning_Resources/Technical_Notes/Mouse_BCR_Profiling?sitex=10020:22372:US&PEBCL1=lU3ZZrMN4ulS3E5aW7KEIoxy7L&PEBCL1_pses=ZGAB93E19422ACD56A49A905AF47DE5A5C1CDD1B1098E068C2FFDD08DAF590F0CDC315E4B045E65DEDC7A87CBBE0C73BDA0F05D783CE2FE9C5
*  Immunoglobulin heavy variable 2-5
Binding and Uptake of Ligands by Scavenger Receptors 100 Antigen activates B Cell Receptor (BCR) leading to generation of ... Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 252 Cell surface interactions at the vascular wall 197 ... Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains ... after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170 ...
  https://pharos.nih.gov/idg/targets/P01817
*  KEGG PATHWAY: B cell receptor signaling pathway
After BCR ligation by antigen, three main protein tyrosine kinases (PTKs) -the SRC-family kinase LYN, SYK and the TEC-family ... B cell receptor signaling pathway [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , User data ... The B cell receptor (BCR) is an integral membrane protein complex that is composed of two immunoglobulin (Ig) heavy chains, two ... They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. ...
  http://www.genome.jp/kegg-bin/show_pathway?ko04662+K05855
*  Transient Inhibition of Interleukin 4 Signaling by T Cell Receptor Ligation | JEM
1997) T cell antigen receptor signal transduction. Curr. Opin. Cell Biol. 9:205-212, pmid:9069257.. ... 1996) T cell antigen receptor signal transduction pathways. Annu. Rev. Immunol. 14:259-274, pmid:8717515.. ... 1996) The interleukin-2 receptor gamma chainits role in the multiple cytokine receptor complexes and T cell development in ... 5 activation during T cell receptor-mediated feedback inhibition of T cell expansion. J. Exp. Med. 190:1263-1274, pmid:10544198 ...
  http://jem.rupress.org/content/192/8/1125
*  F7 / + %%,.&& +2 '.-.+ 0(+$ F7A7 - PDF
... cell receptors (BCRs) necessary to bind diverse antigens and produce an effective humoral immune response. B-cells are dynamic ... T CELL RECEPTOR: STRUCTURE AND GENETIC BASIS T CELL RECEPTOR: STRUCTURE AND GENETIC BASIS Objectives: (1) Present an overview ... Chapter 17A: Adaptive Immunity Part I 1. Overview of Adaptive Immunity 2. T and B Cell Production 3. Antigens & Antigen ... Previous studies have shown that non-b- and non-t-cell malignancies are often marked by profound defects in B-cell and T-cell ...
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*  CD79B - Wikipedia
Müller B, Cooper L, Terhorst C (1995). "Interplay between the human TCR/CD3 epsilon and the B-cell antigen receptor associated ... 1994). "CD5 is associated with the human B cell antigen receptor complex". Eur. J. Immunol. 24 (4): 812-6. doi:10.1002/eji. ... 1995). "Reconstitution of the B cell antigen receptor signaling components in COS cells". J. Biol. Chem. 270 (45): 27072-8. doi ... 1994). "Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45". J. ...
  https://en.wikipedia.org/wiki/CD79B
*  Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies | eLife
Method for identification of condition-associated public antigen receptor sequences Mikhail V Pogorelyy et al. ...
  https://elifesciences.org/articles/33038v1
*  Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer - Full Text...
Patients with prior or concurrent malignancy except for the following: adequately treated basal cell or squamous cell skin ... Pasireotide works by binding to a protein called somatostatin receptor, which is expressed in many tissues throughout the body ... Presence of Hepatitis B surface antigen (HbsAg).. *Presence of Hepatitis C antibody test (anti-HCV). ... Neoplasms, Germ Cell and Embryonal. Neoplasms by Histologic Type. Adenocarcinoma. Carcinoma. Neoplasms, Glandular and ...
  https://clinicaltrials.gov/ct2/show/NCT01270321?term=sirolimus+cancer&recr=Open&rank=17
*  Tissue expression of WWTR1 - Staining in skeletal muscle - The Human Protein Atlas
Cell cycle intensity correlation. Cell cycle spatial correlation. Cell cycle biologically. Custom data cell cycle dependant. - ... G-protein coupled receptors. Mapped to UniProt SWISS-PROT. Nuclear receptors. Plasma proteins. Potential drug targets. ... Blood group antigen proteins. Cancer-related genes. Candidate cardiovascular disease genes. CD markers. Citric acid cycle ... Cell category (RNA). Cancer category (RNA). Tissue detectable (RNA). Cell line detectable (RNA). Cancer detectable (RNA). ...
  http://www.proteinatlas.org/ENSG00000018408-WWTR1/tissue/skeletal+muscle
*  Recombinant Human PD1 protein (ab114177) | Abcam
Cell Biology. Epigenetics. Metabolism. Developmental Biology. By research area. Immunology. Microbiology. Neuroscience. Signal ... Cell and tissue imaging tools. Cellular and biochemical assays. By product type. Proteins and Peptides. Proteomics tools. ... Cell Biology Apoptosis Receptors Death Receptors Share by email Recombinant Human PD1 protein (ab114177). ...
  http://www.abcam.com/recombinant-human-pd1-protein-ab114177.html
*  PerCP Anti-Human CD2 (RPA-2.10) Flow Cytometry Reagents, Recombinant Proteins, PCR Reagents
CD2, also known as LFA-2, is a receptor for CD58 in the human and is expressed on the cell surface of 80-90% of human ... Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. ... LFA-2, T11, Sheep Red Blood Cell Receptor (SRBC-R), Ly-37. ... CD2 mediates lymphocyte adhesion and is involved in T cell ...
  https://www.tonbobio.com/antibodies-and-reagents/percp-anti-human-cd2-rpa-2-10.html
*  Pfizer and Astellas Announce Positive Top-Line Results from Phase 3 PROSPER Trial of XTANDI (enzalutamide) in Patients with Non...
... is an androgen receptor inhibitor that blocks multiple steps in the androgen receptor signaling pathway within the tumor cell. ... PROSPER enrolled patients with prostate cancer that had progressed, based on a rising prostate-specific antigen (PSA) level ... In preclinical studies, enzalutamide has been shown to competitively inhibit androgen binding to androgen receptors, and ... and there is a rising prostate-specific antigen (PSA) level.[iii] Many men with non-metastatic CRPC will go on to develop ...
  https://finance.yahoo.com/news/pfizer-astellas-announce-positive-top-090000228.html
*  ASMscience | Lyme Borreliosis
... assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell ... The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor. Proc. Natl. Acad. Sci. USA 91: ... T-helper-cell cytokines in the early evolution of murine Lyme arthritis. Infect. Immun. 65:3107-3111.. ... Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nat. Med. 5:1375-1382.. ...
  http://www.asmscience.org/content/book/10.1128/9781555816490.chap11
*  Nitroglycerine-Induced Nitrate Tolerance Compromises Propofol Protection of the Endothelial Cells against TNF-α: The Role of...
... endothelial cell, and myeloid cell antigens in spontaneous and chemically induced hemangiosarcomas and hemangiomas in mice," ... beneficial effects of therapy with the AT1 receptor blocker telmisartan," Arteriosclerosis, Thrombosis, and Vascular Biology, ... J.-M. Li and A. M. Shah, "Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p4. 7. phox. ... in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-α," Circulation Research, vol ...
  https://www.hindawi.com/journals/omcl/2013/678484/ref/
*  Chelators - MP Biomedicals
Apoptosis Cell Biology Immuno Solutions Molecular Biology Proteomics Quality Control Research Diet Sample Preparation Solid ... Anti-Macrophage Scavenger Receptor, Human. *Anti-Melanoma Marker, Human. *Anti-Metalloproteinase 2, Human ... Culture Detect Detection Reagents IHC Isolate (Blood Fractionation) Mycoplasma Removal Stem Cell Antibodies >> View All Immuno ...
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*  RPL24P6 Gene - GeneCards | RPL24P6 Pseudogene
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ... Cell Line Products. * GenScript Custom overexpressing Cell Line Services for RPL24P6 * Browse ESI BIO Cell Lines and PureStem ... NURSA nuclear receptor signaling pathways regulating expression of RPL24P6 Gene:. RPL24P6 Genes that share expression patterns ...
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*  Weight abnormalities in IL-6-sIL-6R mice. (A) An IL-6 | Open-i
Antigens, CD/metabolism. *Body Weight. *Cell Differentiation. *Cell Division. *Cell Separation. *Cytokine Receptor gp130 ... Soluble cytokine receptors modulate the activity of their cognate ligands. Interleukin (IL)-6 in association with the soluble ... Soluble cytokine receptors modulate the activity of their cognate ligands. Interleukin (IL)-6 in association with the soluble ... The high numbers of hematopoietic progenitor cells were reflected by a strong increase of peripheral blood cell numbers. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196150_JEM.peters1a&req=4
*  Home Page | Phoenix Children's Hospital
Phoenix Children's is one of only a handful of centers in the nation offering Chimeric Antigen Receptor T-cell (CAR-T) therapy ...
  http://www.phoenixchildrens.org/es
*  PVALB Gene - GeneCards | PRVA Protein | PRVA Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for PVALB Gene. ... Suggested Antigen Peptide Sequences for PVALB Gene. GenScript: Design optimal peptide antigens:. *Parvalbumin (B1AH73_HUMAN) ... NURSA nuclear receptor signaling pathways regulating expression of PVALB Gene:. PVALB SOURCE GeneReport for Unigene cluster for ...
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*  button what time should you take spironolactone point that
Laparoscopic nephroureterectomy for upper tract transitional cell cancer The Washington University experience. Sci. However, ... в- Specific EBV antibodies в levels of IgM and IgG antibodies against viral capsid antigens (VCA) and nuclear antigen (EBNA) ... In cell lines derived from uveal melanoma, loss of one or both B alleles has been observed; loss of one HLA-A spirлnolactone ... O. Venkatesh P, they demonstrate that mature retinal what can change their architectures and receptor expressions, while glia ...
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*  IL17RD Gene - GeneCards | I17RD Protein | I17RD Antibody
Interleukin 17 Receptor D, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human ... IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling. (PMID: 19079364) Rong Z … Chang Z (Cell ... Suggested Antigen Peptide Sequences for IL17RD Gene. GenScript: Design optimal peptide antigens:. *Sef homolog (I17RD_HUMAN) ... span" data-trigger="SectionLoaded"> Inner Cell Mass (Early Embryonic Tissues) * Human embryonic stem cells (family) ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=IL17RD
*  Tissue expression of AFP - Summary - The Human Protein Atlas
Cell cycle intensity correlation. Cell cycle spatial correlation. Cell cycle biologically. Custom data cell cycle dependant. - ... G-protein coupled receptors. Mapped to UniProt SWISS-PROT. Nuclear receptors. Plasma proteins. Potential drug targets. ... Blood group antigen proteins. Cancer-related genes. Candidate cardiovascular disease genes. CD markers. Citric acid cycle ... Cell category (RNA). Cancer category (RNA). Tissue detectable (RNA). Cell line detectable (RNA). Cancer detectable (RNA). ...
  http://www.proteinatlas.org/ENSG00000081051-AFP/tissue/vulva%252Fanal+skin
*  Patent US6122536 - Implantable sensor and system for measurement and control of blood ... - Google Patents
Lack of insulin inhibits the cell membrane transport of nutrients such as glucose, fatty acids, and amino acids into the cells ... In addition, peripheral tissues of type II diabetics may possess a smaller number of membrane tissue receptors and possibly a ... For example, blood constituents such as tumor markers including, but not limited to, prostate specific antigen (PSA) for ... Fisher, et al., Experience with an Implantable Glucose Sensor as a Prerequisite of an Artificial Beta Cell, Biomed Biochim Acta ...
  http://www.google.com.au/patents/US6122536
*  Gentaur Molecular :Alpha Dia \ Human Non Hodgkins lymphoma Tumor lysate \ HCL-1332
INSR] Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor ... RACK1 GNB2L1 HLC7 PIG21] Receptor of activated protein C kinase 1 (Cell proliferation-inducing gene 21 protein) (Guanine ... AR DHTR NR3C4] Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4). [ELANE ELA2] ... EGFR ERBB ERBB1 HER1] Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein ...
  http://www.antibody-antibodies.com/product_det.php?id=59147&supplier=search&name=Human%20Non_Hodgkins%20lymphoma%20Tumor%20lysate