ADRB3 - SNPedia
ADRB3, the β3-adrenergic receptor, has been connected to obesity and metabolic conditions. ... adrenergic, beta-3-, receptor. EntrezGene. 155. PheGenI. 155. VariationViewer. 155. ClinVar. ADRB3. ...https://snpedia.com/index.php/ADRB3
Anti-beta 3 Adrenergic Receptor antibody (ab101095) | Abcam
Rabbit polyclonal beta 3 Adrenergic Receptor antibody validated for WB and tested in Rat. Immunogen corresponding to synthetic ... Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. ... Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. ... Anti-beta 3 Adrenergic Receptor antibody (ab101095) + Rat kidney tissue lysate. Predicted band size: 44 kDa. ...https://www.abcam.com/beta-3-adrenergic-receptor-antibody-ab101095.html
Beta-3 adrenergic receptor - Wikipedia
Other adrenergic receptors Alpha-1 adrenergic receptor Alpha-2 adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic ... "Mutated human beta3-adrenergic receptor (Trp64Arg) lowers the response to beta3-adrenergic agonists in transfected 3T3-L1 ... is a beta-adrenergic receptor, and also denotes the human gene encoding it. Actions of the β3 receptor include Enhancement of ... Beta adrenergic receptors are involved in the epinephrine- and norepinephrine-induced activation of adenylate cyclase through ...https://en.wikipedia.org/wiki/Beta-3_adrenergic_receptor
beta.3 adrenergic receptor agonists and uses thereof - Patent # 6706743 - PatentGenius
... adrenergic receptor-mediated diseases, conditions, or disorders in a mammal which methods comprise administering to the mammal ... beta..sub.3 adrenergic receptor agonists of structural Formula (I), ##STR1##the stereoisomers and prodrugs thereof, and the ... pharmaceutically acceptable salts of the compounds, stereoisomers and prodrugs, wherein Ar, R, R.sub.1, R.sub.2, R.sub.3, R.sub ... beta..sub.1 and .beta..sub.2 Receptor Selectivity. In vivo selectivity for .beta..sub.1 and .beta..sub.2 receptors may be ...http://www.patentgenius.com/patent/6706743.html
Developing Functional Monoclonal Antibodies for Beta-3 Adrenergic Receptor
Our preliminary data showed that several mAb clones speci cally bound to the receptor while increasing the receptor function by ... Developing Functional Monoclonal Antibodies for Beta-3 Adrenergic Receptor Poster Sep 10, 2014 ... G protein-coupled receptors (GPCRs), one of the most commonly used and successful targets for drugs, are a large family of ... These cell surface receptors are acted on by a wide variety of ligands, including small molecules and soluble proteins. ...https://www.technologynetworks.com/tn/posters/developing-functional-monoclonal-antibodies-for-beta3-adrenergic-receptor-229675
W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample - UCL Discovery
ADRENERGIC RECEPTOR, INSULIN-RESISTANCE, TRP64ARG MUTATION, OBESITY, POLYMORPHISM, ASSOCIATION, GAIN, FAT. UCL classification: ... W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample. INT J OBESITY , 22 (4) 377 - 379. ... W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample ... W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample. ...http://discovery.ucl.ac.uk/97255/
AID 310238 - Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP level relative to...
Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP level relative to isoproterenol. ...https://pubchem.ncbi.nlm.nih.gov/bioassay/310238
Université de Bourgogne - Beta3 adrenergic receptor stimulation in human macrophages inhibits NADPHoxidase activity and induces...
The beta3 adrenergic receptor (β3-AR) stimulation plays a protective role against preterm labor by blocking myometrial ... Abstract : The beta3 adrenergic receptor (β3-AR) stimulation plays a protective role against preterm labor by blocking ... Beta3 adrenergic receptor stimulation in human macrophages inhibits NADPHoxidase activity and induces catalase expression via ... Tarik Hadi, Romain Douhard, Alexandre M Dias, Maeva Wendremaire, Maria Pezzè, et al.. Beta3 adrenergic receptor stimulation in ...https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01578123
A Study to Evaluate Safety and Efficacy of YM178 in Patients With Overactive Bladder - Full Text View - ClinicalTrials.gov
Adrenergic beta-Agonists. Adrenergic Agonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ...https://clinicaltrials.gov/ct2/show/NCT00966004
A Study to Investigate the Effect of Mirabegron (YM178) on Subjects With Mild or Moderate Hepatic Impairment Compared to...
Adrenergic beta-Agonists. Adrenergic Agonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ...https://clinicaltrials.gov/show/NCT01579461
To Evaluate the Effect of Mirabegron (YM178) on Blood Levels of Desipramine When They Are Taken Together - Full Text View -...
Adrenergic beta-Agonists. Adrenergic Agonists. Adrenergic Agents. Neurotransmitter Agents. Molecular Mechanisms of ...https://clinicaltrials.gov/ct2/show/NCT01478568
Patent US5164190 - Subsaturated transdermal drug delivery device exhibiting enhanced drug flux - Google Patents
60/22.5/10/2.5/2.5/2.5 25 3 5.52 1.38 EtOH/H.sub.2 O/Gly/GDO/ML/OA4. 60/22.5/10/2.5/2.5/2.5 75 8 3.35 2.18 EtOH/H.sub.2 O/Gly/ ... 60/28/10/1/1 30 3 13.03 3.35 EtOH/H.sub.2 O/Gly/GMO/ML3. 60/28/10/1/1 25 3 12.98 2.06 EtOH/H.sub.2 O/Gly/GMO/ML4. 60/28/10/1/1 ... 40/54/5/1 40 5 38.8 18.9 EtOH/H.sub.2 O/Gly/GMO 20 12 17.5 5.1 10 6 10.1 3.3 5 3 8.0 1.43. 30/63/5/2 40 6 23.9 10.0 EtOH/H.sub. ... 50/49/1 80 75 3 96.5 9.2 EtOH/H.sub.2 O/GMO 40 75 9 37.4 11.0 20 75 3 25.1 1.93. 50/44/5/1 80 75 6 78.4 36.5 EtOH/H.sub.2 O/Gly ...http://www.google.com.au/patents/US5164190
Annotation score: 3 out of 5
beta3-adrenergic receptor activity Source: Ensembl. *epinephrine binding Source: Ensembl. *norepinephrine binding Source: ... G-protein coupled receptorUniRule annotation. ,p>Information which has been generated by the UniProtKB automatic annotation ... Belongs to the G-protein coupled receptor 1 family.UniRule annotation. ,p>Information which has been generated by the UniProtKB ... It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel ...http://www.uniprot.org/uniprot/Q3UP63
Inhibitory Effects of Toll-Like Receptor 4, NLRP3 Inflammasome, and Interleukin-1β on White Adipocyte Browning | Springer for...
TLR4 NLRP3 inflammasome IL-1β uncoupling protein 1 beige adipocytes brown adipocytes β3-adrenergic receptor ... Human interleukin-1 beta-conditioned medium. mIL-1β-CM. Mouse interleukin-1 beta-conditioned medium ... We report that TLR4 activation by lipopolysaccharide repressed white adipocyte browning in response to β3-adrenergic receptor ... especially the toll-like receptor 4 (TLR4) and Nod-like receptor 3 (NLRP3), on white adipocyte browning. ...https://rd.springer.com/article/10.1007/s10753-017-0718-y
Drug Information Portal - Mobile - U.S. National Library of Medicine - Drug Search Results
A beta3-adrenergic receptor agonist.. A beta3-adrenergic receptor agonist. Synonyms. *. Betanis. ...https://druginfo.nlm.nih.gov/m.drugportal/rn/223673-61-8
KAKEN - Research Projects | treatment using adenovirus vector (KAKENHI-PROJECT-09357009)
This gene, designated WFS1, must have an important role in survival of pancreatic beta cells and neuronal cells. We also found ... Nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1.'Diabetes. 49 ... Publications] Ueda K, et al.: 'Prevalence of the Trp64Arg missense mutation of the beta 3-adrenergic receptor gene in Japanese ... Nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1.'Diabetes. 49 ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09357009/
Interleukin Genetics Receives Notice of Allowance for US Patent for PerioPredict Genetic Risk Test - Bay City Capital
... adrenergic receptor beta 2 (ADRB2 - two SNPs); adrenergic receptor beta 3 (ADRB3); and peroxisome proliferator-activated ... receptor gamma (PPAR-γ). These markers are involved in certain physiological pathways relating to body weight. Certain patterns ...http://baycitycapital.com/portfolio-news/interleukin-genetics-receives-notice-of-allowance-for-us-patent-for-periopredict-genetic-risk-test/
Human promoter genomic composition demonstrates non-random groupings that reflect general cellular function | BMC...
beta3-adrenergic receptor activity. 0.085. purine ribonucleoside catabolism. 0.085. purine ribonucleoside metabolism ... 3. s. c. o. r. e. (. b. ,. j. ). ]. /. [. ∑. j. =. m. m. +. 3. m. a. x. _. s. c. o. r. e. (. j. ). ]. (. 2. ). 0. ≤. c. o. r. e ... The Advanced Technology Center, Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, ... Novel nfat sites that mediate activation of the interleukin-2 promoter in response to t-cell receptor stimulation. Mol Cell ...https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-6-259
Results for 'Cholesterol Metabolism > PCK1 > Primary antibodies' | Abcam: antibodies, proteins,...
LXR beta (7). * MC2 receptor (5). * MC4 Receptor (5). * MVD (4). * MVK (6). ...http://www.abcam.com/products?selected.researchAreas=Cardiovascular--Lipids+%2F+Lipoproteins--Lipid+Metabolism--Cholesterol+Metabolism&selected.targetName=PCK1&selected.productType=Primary+antibodies
Maturity-Onset Diabetes of the Young, Type 10 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Adrenergic Agonists. Phase 4. 18. Adrenergic beta-3 Receptor Agonists. Phase 4. ... Selective Estrogen Receptor Modulators. Phase 2. 38. Testosterone 17 beta-cypionate. Phase 2. ... 17-Hydroxy-(17-beta)-androst-4-en-3-one. 17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro- ... 3. INS p.Arg46Gln. VAR_063729 rs121908260 ClinVar genetic disease variations for Maturity-Onset Diabetes of the Young, Type 10: ...http://www.malacards.org/card/maturity_onset_diabetes_of_the_young_type_10
ICI-118,551 - Wikipedia
"Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic ... Hillman KL, Doze VA, Porter JE (August 2005). "Functional characterization of the beta-adrenergic receptor subtypes expressed ... ICI-118,551 is a selective β2 adrenergic receptor (adrenoreceptor) antagonist. ICI binds to the β2 subtype with at least 100 ... therapeutic use in humans although it has been used widely in research to understand the action of the β2 adrenergic receptor, ...https://en.wikipedia.org/wiki/ICI-118,551
US8110591B2 - 2-aminoaryloxazole compounds as tyrosine kinase inhibitors - Google Patents
More particularly, these compounds are potent and selective c-kit, bcr-abl, FGFR3 and/or Flt-3 inhibitors. ... Beta3 adrenergic receptor agonists and uses thereof US20070021447A1 (en) 2007-01-25. 2-Imino-4-(thio)oxo-5-poly ... Among tyrosine kinase receptors, c-kit is of special interest. Indeed, c-kit is a key receptor activating mast cells, which ... Tyrosine kinases are receptor type or non-receptor type proteins, which transfer the terminal phosphate of ATP to tyrosine ...https://patents.google.com/patent/US8110591?oq=inassignee%3Adoubleclick
Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics
Short Talk: Genetic Deletion of the CB1 Receptor from Dopamine-beta-Hydroxylase Expressing Cells Makes Mice Sensitive to Stress ... Short Talk: 5-HT2C Receptor Agonist Anorectic Efficacy Potentiated by 5-HT1B Receptor Agonist Co-Application; an Effect ... Leptin Receptors in the Brain: Where Do They Matter?. Michael A. Cowley, Monash University, Australia Leptin Modulation of DMH ... Insulin Receptors in the Brain: Where Do They Matter?. Eleftheria Maratos-Flier, Beth Israel Deaconess Medical Center, USA ...https://www.keystonesymposia.org/index.cfm?e=web.Meeting.Program&meetingid=1234
Isoprenaline - DrugBank
... beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as ... Ahlquist RP: Present state of alpha- and beta-adrenergic drugs I. The adrenergic receptor. Am Heart J. 1976 Nov;92(5):661-4. [ ... Ahlquist RP: Present state of alpha- and beta-adrenergic drugs I. The adrenergic receptor. Am Heart J. 1976 Nov;92(5):661-4. [ ... Ahlquist RP: Present state of alpha- and beta-adrenergic drugs I. The adrenergic receptor. Am Heart J. 1976 Nov;92(5):661-4. [ ...https://www.drugbank.ca/drugs/DB01064
Elevated Intraocular Pressure - DrugBank
Beta-1 adrenergic receptor. target. DB00195. Betaxolol. Beta-2 adrenergic receptor. target. ... A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.. DB00484. Brimonidine. Brimonidine is a drug ... A beta-adrenergic antagonist similar in action to propranolol. The levo-isomer is the more active. Timolol has been proposed as ... Beta-1 adrenergic receptor. target. DB00373. Timolol. Beta-2 adrenergic receptor. target. ...https://www.drugbank.ca/indications/DBCOND0034700