Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene. This gene belongs to the ephrin receptor ... "Entrez Gene: EPHA7 EPH receptor A7". Flanagan JG, Vanderhaeghen P (1998). "The ephrins and Eph receptors in neural development ... Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain ... The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their ...

Epha7. Eph receptor A7. involved_in. acts_upstream_of_or_within. ISS. IEA. ISO. GO_REF:0000024. GO_REF:0000107. MGI:3583808 ( ... dopamine receptor D2. acts_upstream_of_or_within. ISO. MGI:2387895 (MGI:2136539,PMID:11438590). RGD. PMID:11438590. MGI:2136539 ... fibroblast growth factor receptor 2. acts_upstream_of_or_within. ISO. MGI:2153811 (MGI:3763776,PMID:17951031). RGD. PMID: ...

Eph receptor A4/SEK (10). * Eph receptor A7/EPHA7 (6). * Eph receptor B1/NET (6). ... GABA A Receptor alpha 2/GABRA2 (6). * GABA A Receptor beta 2/GABRB2+GABA A Receptor beta 3/GABRB3+GABA A Receptor gamma 2/ ... Metabotropic glutamate receptor (27). * Metabotropic Glutamate Receptor 2/MGLUR2+Metabotropic Glutamate Receptor 3/MGLUR3 (13) ... Mu Opioid Receptor (13). * Muscarinic Acetylcholine Receptor 2/CM2+Muscarinic Acetylcholine Receptor 1/CHRM1+Muscarinic Acetylc ...

SAM domain of human ephrin type-a receptor 7 (EPHA7). 3hil. SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1). ... Sterile alpha motif (SAM) domain of ephrin type-A receptor 8. 1v38. Solution structure of the Sterile Alpha Motif (SAM) domain ... The weak capability of the isolated EphB2 receptor SAM domain to form oligomers is supposed to be relevant in vivo when the ... The structure reveals a mode of dimerization that we predict is shared amongst the SAM domains of the Eph receptor tyrosine ...

EPHA1, EPHA2, EPHA4, EPHA7, EFNA3, EFNA4, and EFNA5 were upregulated in estrogen receptor- (ER-) and progesterone receptor- (PR ... The Kaplan–Meier plotter indicated that high EphA7 mRNA expression was associated with poor overall survival (OS) and ... EPHA1, EPHA2, EFNA3, and EFNA4 mRNA expression was significantly higher in human epidermal growth factor receptor 2- (HER2-) ... Triple-negative status was positively correlated with EPHA1, EPHA2, EPHA4, EPHA7, EFNA3, EFNA4, and EFNA5 and negatively ...

The frequent mutations in immune receptor genes (HVEM, BTLA, EPHA7, beta-2 micro-globulin) that control lymphoma cell growth ... Notably, these receptors act on the cell surface and they are readily accessible to antibody conjugates and ligand-producing ...

EphA4 and EphA7). However, the Hox gene family and the Ephrin/Eph receptor gene families appear to be the most important for ... 8] Negative regulators include the ephrins and their Eph receptors, as well as the class 3 semaphorins and their neuropilin/ ... A similar role is performed by the EGF-like receptor ErbB4. Cephalic NC cells also encounter physical barriers; the otic ... plexin receptors. These genes prevent the entry of NC cells into specific zones. ...

EphA7, EphA10, EphB1, EphB3, EphB4, ErbB2, ErbB3, ErbB4, ErbB6, FGFR1, FGFR2 alpha, FGFR3, FGFR4, Flt-3/Flk, HGF R/c-MET, IGF-I ... The epidermal growth factor receptor (EGFR) is a HER-family receptor tyrosine kinase (RTK) that is involved in cell signaling ... The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (RTK) commonly targeted for inhibition by anti-cancer ... The density of the receptors expressed was in the range of 100-2000 receptors/μm2. Lower Deff and higher fc values indicate ...

... fibroblast growth factor receptor (FGFR) Ser249Cys mutation dimerizes the receptor and leads to constitutive signaling by ... EphA7 Arg676, located in the N-terminal helix, and EphB1 Gly685, situated on the beta-strand, can play a significant role in ... Eph receptor belongs to the largest family of RTK. Based on sequence homology, Eph and ephrin have been classified into EphA/ ... Knockdown of ephrin receptor A7 suppresses the proliferation and metastasis of A549 human lung cancer cells. Mol Med Rep 2016; ...

Toll-like receptor signaling pathway 12. NOD-like receptor signaling pathway 13. RIG-I-like receptor signaling pathway 14. T ... Nanoparticle-mediated activation of receptor signaling 6. Signal Transduction of S1P Receptor 7. Parkinsons Disease Pathway 8. ... EGF receptor signaling pathway 4. FGF signaling pathway 5. Interferon-gamma signaling pathway 6. Oxidative stress response 7. ... Toll-like receptor signaling pathway 2. Insulin Signaling 3. MAPK Cascade 4. MAPK Signaling Pathway 5. ...

Receptors expressed. Receptor tyrosine kinases EGFR, EphA7, PDGFRalpha, FGFR1, PDGFRbeta, AxL. Tumorigenic. Yes, in nude mice. ...

Receptor tyrosine kinase EphA7 is required for interneuron connectivity at specific exploit compartments of granule cells. The ...

Cell signalling receptors of ephrins, namely EphA5 and EphA7, were identified as novel negative regulators of henipavirus ... This is evidence of species specific ephrin receptor usage by a henipavirus, and implicates additional ephrin receptors in ... CedV receptor-binding protein (G) shares only â ¼30% sequence identity with those of NiV and HeV, although they can all use ... Cell receptor use by emerging African HNVs at the stage of host-cell entry is a key parameter when considering the potential ...

The putative tumor suppressor gene EphA7 is a novel BMI-1 target. Prost, G., Braun, S., Hertwig, F., Winkler, M., Jagemann, L. ... Platelet-Derived Growth Factor beta Receptor 58% * Neoplasms 27% * Paracrine Communication 12% ...

Ciossek T, Ullrich A, West E, Rogers JH (1999) Segregation of the receptor EphA7 from its tyrosine kinase-negative isoform on ... Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex Condividi "Eph receptors ... Eph receptor activation and inhibition have been reported to affect dendritic spines in the hippocampus. EphB receptor ... Such repression persists after Eph receptor activation, but is overridden by Eph receptor inhibition with EphA4/Fc in neonatal ...

The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of ... Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to ... GPI-linked ephrin receptor activity. EPHA8;EPHA7;EPHA4;EK1;EPHA5;EPHA3. protein binding. PBLD;EGLN1;CDC25C;IFT20;MAPK15;BRAP; ... Recombinant Human EPH Receptor A3, His-tagged E.coli. His. Inquiry. Human. EPHA3-301H. Recombinant Human EPH Receptor A3, GST- ...

RECEPTOR DE EPHA5, RECEPTOR DE EPHA6, RECEPTOR DE EPHA7 y RECEPTOR DE EPHA8. Se encuentra principalmente en el TEJIDO NERVIOSO. ... EPHA5 RECEPTOR; EPHA6 RECEPTOR; EPHA7 RECEPTOR; and EPHA8 RECEPTOR. It is found primarily in NERVE TISSUE. ... EPHA5 RECEPTOR; EPHA6 RECEPTOR; EPHA7 RECEPTOR; and EPHA8 RECEPTOR. It is found primarily in NERVE TISSUE.. ... Ciliary Neurotrophic Factor Receptor alpha Subunit [D12.776.395.550.448.200] Ciliary Neurotrophic Factor Receptor alpha Subunit ...

D12.776.543.750.630.500.250 Receptor, EphA6 D12.776.543.750.60.500.300 D12.776.543.750.630.500.300 Receptor, EphA7 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...

D12.776.543.750.630.500.250 Receptor, EphA6 D12.776.543.750.60.500.300 D12.776.543.750.630.500.300 Receptor, EphA7 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...

D12.776.543.750.630.500.250 Receptor, EphA6 D12.776.543.750.60.500.300 D12.776.543.750.630.500.300 Receptor, EphA7 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...

D12.776.543.750.630.500.250 Receptor, EphA6 D12.776.543.750.60.500.300 D12.776.543.750.630.500.300 Receptor, EphA7 D12.776. ... Receptor Aggregation G4.299.780 G4.774 Receptor Cross-Talk G4.299.785 G4.794 Receptor Protein-Tyrosine Kinases D12.776.543.750. ... 60 D12.776.543.750.630 Receptor Tyrosine Kinase-like Orphan Receptors D12.776.543.750.60.233 D12.776.543.750.630.233 Receptor, ... Receptor Activator of Nuclear Factor-kappa B D23.50.301.264.35.594 D23.101.100.110.594 Receptor Activity-Modifying Protein 1 ...

Receptor-type tyrosine-protein phosphatase C; TLR8: Toll-like receptor 8; CD86: lymphocyte activation antigen CD86; CXCL8: ... Increased expression of epha7 in inflamed human dental pulp. J Endod. 2013;39:223-7. doi:10.1016/j.joen.2012.11.020. ... Receptor-type tyrosine-protein phosphatase C. Protein tyrosine-protein phosphatase required for T-cell activation through the ... CD86 is a receptor that commonly participates in T-lymphocyte proliferation and IL-2 production, acting as a negative regulator ...

two like one, which anchors protein kinase C to your cytoskeleton, EPHA7, the receptor for that A1 to 5 members on the ephrin A ... the receptor for nicotinic acid GPR109B, IRS4, which interfaces between lots of growth elements and intracellular signaling ... a peripheral membrane protein that could act to organize transmem brane receptors and binds to signal transduction mole cules ... molecules, TYK2, which phosphorylates receptors in the Janus kinase /signal transducer and activator of transcription pathway ...

Cell-cell communication is mediated by membrane receptors and their ligands, such as the Eph/ephrin system, orchestrating cell ... which involves EphA4 receptor activation and signaling [6]. The same receptor was identified to mediate the repellent response ... Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model. J Hematol Oncol. 2015 ... such as the fibroblast growth factor receptor (FGFR) and chemokine receptors, as well as cell adhesion molecules such as ß- ...

VIP Receptor 2, Visfatin, Vitamin D Receptor, Vitamin D-BP, Vitamin K-dependent protein S, Vitronectin, VWF, WIF-1, Wilms Tumor ... EphA7, EphA8, EphB1, EphB2, EphB3, EphB4, EphB6, Ephrin-B1, Ephrin-B2, EPHX2, Epiregulin, EPPK1, Eps15, ERAB, ErbB2, ErbB3, ... VIP Receptor 2, Visfatin, Vitamin D-BP, Vitamin D Receptor, Vitamin K-dependent protein S, Vitronectin, VNN1, VSIG4, VWF, WDR1 ... Endothelin Receptor A, Enolase 2, ENPP2, EN-RAGE, Eotaxin / CCL11, Eotaxin-2 / MPIF-2, Eotaxin-3 / CCL26, EpCAM, EphA1, EphA2, ...

A DNA sequence encoding the mouse EPHA7 isoform 1 (Q61772-1) extracellular domain (Met 1-Ile 556) was fused with a His tag at ... Interleukins and Receptors Growth Factors and Receptors Chemokines and Receptors Tumor Necrosis Factors and Receptors (TNFs) ... Ephrin type-A receptor 7, also known as EphA7, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family ... Down-regulation of EphA7 secondary to hypermethylation has been reported in colorectal cancer. The expression of EphA7 was ...

Receptor tyrosine kinases (RTKs) play a key role in tumor development. Tie2, a transmembrane RTK, presents predominantly on ... whereas the extent of phosphorylation to EphA7 was too weak to be recognized as a mechanism involving tumor signaling ... GTP-bound Ras protein were detected as described previously [10]. Screening of 13 RTK families of 42 receptors of human RTK ... We used an anti-phospho-tyrosine receptor antibody array [for 42 human RTKs] to determine those RTKs activated in breast cancer ...

Toll-like receptor 8; ICAM1: Intercellular adhesion molecule 1; MMP9: Matrix metalloproteinase-9; CCL2: C-C chemokine receptor ... Increased expression of epha7 in inflamed human dental pulp. J Endod. 2013;39:223-7. doi:10.1016/j.joen.2012.11.020. ... Receptor-type tyrosine-protein phosphatase C;. Protein tyrosine-protein phosphatase required for T-cell activation through the ... CD86 is the receptor that commonly participates in the processes of T-lymphocyte proliferation and IL-2 production, acting as a ...

... such Rabbit Polyclonal to EPHA7 (phospho-Tyr791) as Notch and Hedgehog (Hh) signalling (Laky and Fowlkes, 2008; Solanki et al ... with continued CD4 co-receptor expression allowing for prolonged stronger MHCII-TCR signalling, leading to differentiation to ...

EphA7.kin_dom. Protein Kinase Domain. Sugen global kinase HMM prediction. 257. Kinase domain by global Sugen HMM. Fasta, JSON ... EphA7.AA. SFK-Src. 633-894. 41. 3.4e-105. 312.76. In-house. 1-259 (259). Show / Hide. ... EphA7.AA. TK-Unique. 633-890. 34. 5.3e-95. 321.93. In-house. 1-294 (294). Show / Hide. ... EphA7.AA. Ephrin_lbd. 32-205. 68. 8.20000000001e-143. 445.22. Pfam. 1-190 (190). Show / Hide. ...