Zucker Rat Syndrome: By The Numbers
Zucker Rat Syndrome Rigorous Honesty, in the search of recovery from gross obesity. Mainly opinion, not advice. Some ...http://philosophyofweightmanagement.blogspot.com/2011/05/by-numbers.html
Cardiovascular dysfunction is caused by pre-existing hydronephrosis in young lean, obese and diabetic Zucker rats - UQ eSpace
Cardiovascular dysfunction is caused by pre-existing hydronephrosis in young lean, obese and diabetic Zucker rats. Marsh, Susan ... Cardiovascular dysfunction is caused by pre-existing hydronephrosis in young lean, obese and diabetic Zucker rats ... obese and diabetic Zucker rats. In: The FASEB Journal. Experimental Biology 2006 Meeting, San Francisco, CA, (A298-A298). 1-5 ...https://espace.library.uq.edu.au/view/UQ:166563
Abstract 507: Metabolic Regulation of Coronary Vascular Tone in Metabolic Syndrome | Circulation
Isolated cardiac myocytes (CM) in OZR and age matched lean Zucker rats (LZR) were stimulated at 400 beats/min to increase ... that a derangement in the production of vasodilator metabolites by metabolically active cardiac myocytes from obese Zucker rats ...http://circ.ahajournals.org/content/114/Suppl_18/II_78.2
Kindke's Scrap Notes
Relationship of adipocyte size to hyperphagia in developing male obese Zucker rats.. Abstract. In growing male obese Zucker ... Serum from lipectomized rats, but not media conditioned by exposure to retroperitoneal fat pads from lipectomized rats, ... So again more evidence adipose tissue is controlling appetite and since this is in zucker rats something other than leptin is ... In fat-fed obese rats, hyperphagia reached a breakpoint at 11 wk and disappeared by 13 wk. In chow-fed obese rats, hyperphagia ...http://kindkehealthnotes.blogspot.com
Restoration of Euglycemia After Duodenal Bypass Surgery Is Reliant on Central and Peripheral Inputs in Zucker fa/fa Rats |...
Our results show that duodenal bypass surgery on obese, insulin-resistant Zucker fa/fa rats restored insulin sensitivity in ... Restoration of Euglycemia After Duodenal Bypass Surgery Is Reliant on Central and Peripheral Inputs in Zucker fa/fa Rats ... Restoration of Euglycemia After Duodenal Bypass Surgery Is Reliant on Central and Peripheral Inputs in Zucker fa/fa Rats ... Restoration of Euglycemia After Duodenal Bypass Surgery Is Reliant on Central and Peripheral Inputs in Zucker fa/fa Rats ...http://diabetes.diabetesjournals.org/content/early/2012/12/14/db12-0681
Rosiglitazone Treatment Restores Renal Dopamine Receptor Function in Obese Zucker Rats | Hypertension
Eight- to 9-week-old male obese Zucker rats and age-matched male lean Zucker rats (Harlan Sprague-Dawley Inc) were housed in ... Zucker LM, Zucker TF. Fatty, a new mutation in the rat. J Hered. 1961; 52: 275.. ... This notion is supported by our studies performed in rat model of hyperinsulinemia/type 2 diabetes, obese Zucker rats.16,17⇓ We ... was similar in 3 groups of rats (lean rats, 242.3±15.12; obese control rats, 209.5±46.08; obese rosiglitazone-treated rats, ...http://hyper.ahajournals.org/content/40/6/880
Oral administration of interferon tau enhances oxidation of energy substrates and reduces adiposity in Zucker diabetic fatty...
Male Zucker diabetic fatty (ZDF) rats were used to study effects of oral administration of interferon tau (IFNT) in reducing ... Eighteen ZDF rats (28 days of age) were assigned randomly to receive 0, 4, or 8 μg IFNT/kg body weight (BW) per day (n = 6/ ... These results indicate that IFNT stimulates oxidation of energy substrates and reduces obesity in ZDF rats and may have broad ... Energy expenditure in 4-, 6-, 8-, and 10-week-old rats was determined using indirect calorimetry. Starting at 7 weeks of age, ...http://onlinelibrary.wiley.com/doi/10.1002/biof.1113/abstract
Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes | Diabetes
Evolution of beta cell dysfunction in the male Zucker diabetic fatty rat. Diabetes44 :1447 -1457,1995. ... These changes have been found in islets from both diabetic ZDF rats (28) and rats following partial pancreatectomy in which ... 3). Although a spectrum of glucose levels was seen at 4 weeks, the rats showed two distinct outcomes by 14 weeks: they were ... Trent DF, Fletcher DJ, May JM, Bonner-Weir S, Weir GC: Abnormal islet and adipocyte function in young B-cell deficient rats ...http://diabetes.diabetesjournals.org/content/53/suppl_3/S16.full
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity |...
Lanes 1 and 6, 14-wk-old ZCL rats; lanes 2 and 7, 14-wk-old ZDF rats; lanes 3 and 8, 20-wk-old ZCL rats treated with vehicle ... 6J) seen in ZDF-V rats compared with that in ZCL-V rats was not altered in ZDF-CA rats, suggesting no alteration of the effect ... At 14 wk of age, compared with ZCL rats, GK protein in liver of ZDF rats was ∼80% of that in ZCL rats, albeit not significantly ... 7, J, M, and N, and 8J). In ZDF-CA rats, similar to ZCL-V rats, the N/C of GK decreased markedly during the clamp after both ...http://ajpendo.physiology.org/content/306/11/E1225.long
Effect of Obesity on Serum Vitamin D Metabolites Using Obese Zucker Rat Model
... in rats. Sixteen 5-week-old female Zucker rats (8 obese fa/fa and 8 lean) were acclimated for one week, and at the age of 42 ... Effect of Obesity on Serum Vitamin D Metabolites Using Obese Zucker Rat Model. The obesity epidemic in the US has continued for ... Rats were weighed twice weekly. At the end of the experiment (8 weeks), all rats were sacrificed and serum was collected and ... Obese rats had significant weight gain (P,0.001). Serum concentration of 25-(OH)-D metabolite in obese rats was significantly ( ...https://www.omicsonline.org/blog/2015/05/16/12874-Effect-of-Obesity-on-Serum-Vitamin-D-Metabolites-Using-Obese-Zucker-Rat-Model.html
Development of thyroxine type II deiodinase activity in brains of Zucker rats | Biochemical Journal
... in brains of pre-obese rats; concurrently, serum free T4 increased in Fa/fa rats, whereas it did not change in fa/fa rats. The ... Development of thyroxine type II deiodinase activity in brains of Zucker rats. V Marie, F Dupuy, R Bazin ... Development of thyroxine type II deiodinase activity in brains of Zucker rats ... Development of thyroxine type II deiodinase activity in brains of Zucker rats ...http://www.biochemj.org/content/304/1/259
Effect of Dehydroepiandrosterone on Neurotransmitter Levels and Appetite Regulation of the Obese Zucker Rat: The Obesity...
... dehydroepiandrosterone's effect at decreasing food intake and body weight in the obese Zucker rat was investigated. Rats were ... The obese Zucker rat is a model of youth-onset obesity associated with hyperphagia. In this study, ... Effect of Dehydroepiandrosterone on Neurotransmitter Levels and Appetite Regulation of the Obese Zucker Rat: The Obesity ... Effect of Dehydroepiandrosterone on Neurotransmitter Levels and Appetite Regulation of the Obese Zucker Rat: The Obesity ...http://diabetes.diabetesjournals.org/content/42/5/662
NN414, a SUR1/Kir6.2-Selective Potassium Channel Opener, Reduces Blood Glucose and Improves Glucose Tolerance in the VDF Zucker...
Data from vehicle-treated rats (○), discontinued NN414-treated rats (□), and continued NN414-treated rats (▵) are shown. Data ... The VDF Zucker (fa/fa) rat strain has been established at the Department of Physiology, University of British Colombia (14). ... Alemzadeh R, Slonim AE, Zdanowicz MM, Matruo J: Modification of insulin resistance by diazoxide in obese Zucker rats. ... The observation that fasting blood glucose and plasma insulin are lower in both NN414-treated rats and control-treated rats ...http://diabetes.diabetesjournals.org/content/52/10/2513
A diet containing a high- versus low-daidzein level does not protect against liver steatosis in the obese Zucker rat model -...
A diet containing a high- versus low-daidzein level does not protect against liver steatosis in the obese Zucker rat model ... A diet containing a high- versus low-daidzein level does not protect against liver steatosis in the obese Zucker rat model A. ... diet is associated with significantly heavier body weights and reduced liver steatosis in obese Zucker rats (OZR) compared to a ... We used 19 five-week-old female OZR (fa/fa). Rats were randomly assigned to a modified AIN-93G diet containing HD (0.121 g kg−1 ...http://pubs.rsc.org/is/content/articlelanding/2017/fo/c6fo01772j
Satellite cell proliferation is reduced in muscles of obese Zucker rats but restored with loading | Cell Physiology
The obese Zucker rat (OZR) is a model of metabolic syndrome, which has lower skeletal muscle size than the lean Zucker rat (LZR ... LZR, lean Zucker rat; OZR, obese Zucker rat; −7, 7 days of loading; −21, 21 days of loading. *P , 0.05 vs. contralateral ... the obese zucker rat (OZR) is a widely accepted model of metabolic syndrome, which occurs as a result of a homozygous missense ... Phillips MS, Liu Q, Hammond HA, Dugan V, Hey PJ, Caskey CJ, Hess JF. Leptin receptor missense mutation in the fatty Zucker rat ...http://ajpcell.physiology.org/content/295/2/C521
Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in...
Male Zucker rats (5-week old) were supplemented with vehicle (control) and HCA-SX in drinking water for 7 weeks. Oxidative ... These results suggest that HCA-SX supplementation in obese Zucker rats reduces food-intake, body weight gain, and also ... hydroxycitric acid on the metabolic syndrome in aged diabetic Zucker fatty rats. Mol Cell Biochem 252:369-377PubMedCrossRef ... and restores D1 receptor-G-protein coupling and function in obese Zucker rats. Diabetes 54:2219-2226PubMedCrossRefGoogle ...https://link.springer.com/article/10.1007%2Fs11010-007-9489-3
Normalization of Skeletal Muscle Glycogen Synthesis and Glycolysis in Rosiglitazone-Treated Zucker Fatty Rats | Diabetes
... during a euglycemic-hyperinsulinemic clamp in awake Zucker fatty rats. Three groups of Zucker fatty rats (fatty rosiglitazone [ ... Zucker obese (fa/fa) rats and their lean littermates (Harlan, Indianapolis, IN) were housed in an environmentally controlled ... The aim of this study was to characterize insulin-stimulated skeletal muscle glucose metabolism in Zucker fatty rats and to ... The data reported here show that after 7-day rosiglitazone treatment in the Zucker fatty rat, insulin-stimulated whole-body ...http://diabetes.diabetesjournals.org/content/51/7/2066
CiNii 論文 - The Novel Hypoglycemic Agent YM440 Improves Hepatic Insulin Resistance in Obese...
Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats ... The Novel Hypoglycemic Agent YM440 Improves Hepatic Insulin Resistance in Obese Zucker Fatty Rats * * Nakano Ryosuke NAKANO ... The effect of CP 68,722, a thiozolidinedione derivative, on insulin sensitivity in lean and obese Zucker rats BOWEN L. ... Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone SREENAN S ...https://ci.nii.ac.jp/naid/10018236505
Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats.
... rat, a model of obesity. Specifically, these rats were fed an isocaloric diet containing various combinations of carbohydrates ... Linoleic-acid-fed rats (PL and SL) exhibited reduced insulin-immunoreactive staining of the pancreatic islets, enhanced ... and an elevated plasma tumor necrosis factor-alpha concentration when compared with oleic-acid-fed rats (PO and SO). ... effects of different types of dietary carbohydrates and fats on the etiology of obesity and its complications in the Zucker ...http://www.biomedsearch.com/nih/Dietary-palatinose-oleic-acid-ameliorate/17634263.html
Zucker Rat Syndrome: Social Pressure
Zucker Rat Syndrome Rigorous Honesty, in the search of recovery from gross obesity. Mainly opinion, not advice. Some ...http://philosophyofweightmanagement.blogspot.com/2011/12/social-pressure.html
Sean Daniel - Wikipedia
Jerry Zucker's Rat Race; John Woo's first American film, Hard Target; The Jackal, which starred Richard Gere and Bruce Willis; ...https://en.wikipedia.org/wiki/Sean_Daniel
Pinellia ternata - Wikipedia
Kim, YJ; Shin, YO; Ha, YW; Lee, S; Oh, JK; Kim, YS (2006). "Anti-obesity effect of Pinellia ternata extract in Zucker rats". ... One study found that high doses of Pinellia extract effects thermogenesis and fatty acid oxidation in Zucker rats. Kew World ...https://en.wikipedia.org/wiki/Pinellia_ternata
Ob/ob mouse - Wikipedia
Zucker rat Ingalls AM, Dickie MM, Snell GD (December 1950). "Obese, a new mutation in the house mouse". J. Hered. 41 (12): 317- ...https://en.wikipedia.org/wiki/Ob/ob_mouse
TAS1R1 - Wikipedia
White BD, Corll CB, Porter JR (1989). "The metabolic clearance rate of corticosterone in lean and obese male Zucker rats". ... Abaffy T, Trubey KR, Chaudhari N (2003). "Adenylyl cyclase expression and modulation of cAMP in rat taste cells". American ... "Taste preference synergy between glutamate receptor agonists and inosine monophosphate in rats". Chemical senses. 25 (5): 507- ...https://en.wikipedia.org/wiki/TAS1R1
Nitroglycerine-Induced Nitrate Tolerance Compromises Propofol Protection of the Endothelial Cells against TNF-α: The Role of...
P. J. Wickley, X. Ding, P. A. Murray, and D. S. Damron, "Propofol-induced activation of protein kinase C isoforms in adult rat ... Y.-L. Li, L. Gao, I. H. Zucker, and H. D. Schultz, "NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced ... S. Lei, H. Li, J. Xu et al., "Hyperglycemia-induced PKCbeta2 activation induces diastolic cardiac dysfunction in diabetic rats ... liver and kidney in streptozotocin-induced diabetic rats," Yonsei Medical Journal, vol. 53, no. 2, pp. 294-303, 2012. View at ...https://www.hindawi.com/journals/omcl/2013/678484/ref/
Download our free solidary book to support research on VHL disease