Rats, Mutant Strains * Streptozocin Substances * Streptozocin Grants and funding * R3703306/PHS HHS/United States ...

Strain reports include a comprehensive description of function and biological process as well as disease, expression, ... mutant. Source:. Horizon Discovery. Origin:. This strain was produced by injecting ZFNs into Crl:LE rat embryos. The resulting ... Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive ... Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature ...

... a new neurological mutant rat in the Wistar strain". Acta Neuropathologica. 76 (4): 366-372. doi:10.1007/bf00686973. PMID ... The biobreeding rat (a.k.a. the biobreeding diabetes-prone rat or BBDP rat) is an inbred strain that spontaneously develops ... "Rat Genome", Nature Rat Genome Database, Medical College of Wisconsin Index of Inbred Rat Strains database, Jacskson Laboratory ... and these rats are usually referred to as "stocks" rather than "strains". The Wistar rat is an outbred albino rat. This breed ...

Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive ... Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature ... Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal ... Genes Community Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data ...

Rat Resource & Research Center. Providing top quality animals to the research community. ... Rats on the rise. July 20, 2021. Rats on the rise. Ellen P. Neff (Lab Animal, 2021). After a genetic revolution in the 80s, ... The RRRC is fully operational at this time and we are excited to be able to assist researchers with all their rat-related needs ... April 4, 2023 is World Rat Day! The RRRC would like to acknowledge the important contributions to science and medicine made ...

Rat Resource & Research Center. Providing top quality animals to the research community. ... Rats on the rise. July 20, 2021. Rats on the rise. Ellen P. Neff (Lab Animal, 2021). After a genetic revolution in the 80s, ... The RRRC is fully operational at this time and we are excited to be able to assist researchers with all their rat-related needs ... April 4, 2023 is World Rat Day! The RRRC would like to acknowledge the important contributions to science and medicine made ...

... via an in vitro binding assay that miR-9a binds to sNPFR1 mRNA in insect cells and to the mammalian orthologue NPY2R in rat ... 6c,f). In addition, miR-9a−/− null mutant flies produce significantly more sNPFR1 protein than the wild-type control strain ( ... Mutant sNPFR1 and NPY2R 3′-UTR clones induced in CLIP assays in Drosophila S2 and rat INS-1 cells, respectively. (b,e) miRNA- ... h) Adult 4E-BP expression is reduced in the miR-9aE39/J22 null mutants compared with WT, miR-9aJ22/+ and miR-9aE39/+ ...

... of mutagenicity was observed in a microbial mutagen test using mutant strains of Salmonella typhimurium with or without rat or ... affected rat fetuses/total: 6/324 compared to 2/308 in the control group). Female rats dosed before mating through gestation at ... In pregnant rats given doses of 2, 20, or 200 mg/kg/day and treated through lactation, the following effects were observed: ... However, in studies with a similar drug in this class, there was decreased fertility in male rats treated for 34 weeks at 25 mg ...

The LEC rat is known to be a mutant strain that spontaneously develops heritable hepatitis due to copper accumulation, caused ... on KCl-stimulated release of DA in the striatum in sham-irradiated and irradiated rats was determined. Exposure of rats to 1-10 ... It has previously been shown that exposing rats to particles of high energy and charge (HZE) disrupts the functioning of the ... These findings are similar to those seen in aged rats, suggesting that an increased release of reactive oxygen species may be ...

Rats, Mutant Strains (MeSH) * Sodium Channel Blockers (MeSH) * Tetrodotoxin (MeSH) published in * American Journal of ... Pacemaker activity and inhibitory neurotransmission in the colon of Ws/Ws mutant rats Academic Article ... In Ws/Ws rats, the density of KIT-positive cells was markedly reduced. Wild-type, but not Ws/Ws, rats showed low- and high- ... In Ws/Ws rats, irregular patterns of action potentials triggered irregular muscle contractions occurring within a bandwidth of ...

In the presence of 10% rat liver S9, doses up to 7,500 μg/plate did not induce an increase in mutant colonies in TA100. In ... metallic cobalt was tested in strain TA98, cobalt chloride was tested in strain TA97a and cobalt sulfate was tested in strain ... As there are no details, it is not clear how the possible outcome of non-mutant microcolonies resembling mutant colonies at ... The mutant frequencies at these concentrations exceeded both historical control ranges and concurrent control mutant ...

The Rat Strain Ontology (RS) is currently being developed at the Rat Genome Database. For more information about this ... Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive ... Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature ... Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal ...

... using mutant strains of Salmonella typhimurium or Escherichia coli; a forward mutation assay in L5178Y TK +/- mouse lymphoma ... In pregnant rats given oral gavage doses of 10, 100, and 1,000 mg/kg/day from gestation day 17 through lactation day 21 ( ... In pregnant rats, pravastatin crosses the placenta and is found in fetal tissue at 30% of the maternal plasma levels following ... In pregnant rats given oral gavage doses of 4, 20, 100, 500, and 1,000 mg/kg/day from gestation days 7 through 17 ( ...

... indicating a strain-dependent toxicity of α-synuclein aggregates, which support a prion-like behavior of α-synuclein. ... One α-synuclein strain inhibited proteasome activity and induced apparent pathologies, while the other did not, ... To test this, rats were fear conditioned in protocols of varying intensities to generate mild or strong memories. Neuronal ... extracts exhibit distinct infectivity compared to PD or control brain extracts in cultured cells or mice expressing mutant A53T ...

dominant-negative mutant」「mutant allele」「mutant rat strain」「mutant background」「cell division cycle mutant」. ... Mutant Label. MUTANT LABELのウェブサイトです。 Infomation Garally Online MUTANT LABELのウェブサイトです。 Infomation Garally Online .... *サウンド素材集の一 ... MUTANT , MUTANT MASS , Muscle Bodybuilding Supplements. The scientifically advanced MUTANT supplements provide bodybuilders ... mutant. 関. 突然変異種、変異、変異株、変異体、ミュータント、

Rats (MeSH) * Rats, Mutant Strains (MeSH) * Stress, Psychological (MeSH) published in * Gastroenterology Journal ... METHODS: Mast cell-deficient (Ws/Ws) rats and wild-type control (+/+) rats were submitted to water avoidance stress or sham ... RESULTS: Both rat groups had similar systemic responses to stress, as assessed by changes in weight, corticosterone levels, and ... In +/+ rats, chronic stress induced barrier dysfunction in the ileum and colon (increased macromolecular permeability and ...

... including the C3H/HeJ strain which expresses an LPS-resistant mutant TLR4. Expression of TLR4-MD-2 is down-regulated on ... including the C3H/HeJ strain which expresses an LPS-resistant mutant TLR4. Expression of TLR4-MD-2 is down-regulated on ... MTS510 mAb detects TLR4-MD-2 on the surface of thioglycollate-elicited macrophages from all mouse strains tested (ie, BALB/c, ... MTS510 mAb detects TLR4-MD-2 on the surface of thioglycollate-elicited macrophages from all mouse strains tested (ie, BALB/c, ...

CNS Pathology in the neurological mutant rats zitter, tremor and zitter-tremor double mutant (spontaneously epileptic rat, SER ... NBRP Rat No: 0015. Strain name: TRM/Kyo. Commmon Name: TRM, tremor rat. Rat Genome Database. ... In F18 progeny, a rat which did not have tm mutation was separated and established as a control strain of WTC (NBRP No.0020). ( ... In 1980, a spontaneous tremor mutant rat was found in the colony of Kyo:Wistar (Yamada, 1985). This disorder was found to be ...

Mutant. Transgene. Ind. Mutant. Category Other Comercial Availability. Research Category. Diabetes Obesity. Neurobiology. ... NBRP Rat No: 0694. Strain name: F344-Il2rgem7Kyo. Commmon Name: XSCID-TALEN. Rat Genome Database. ... Strain characteristics. This strain shows severe combined immunodeficiency caused by a 7-bp deletion in the exon 2 of Il2rg ... Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay. mSphere. 2016 Dec 21 ...

Strain reports include a comprehensive description of function and biological process as well as disease, expression, ... mutant. Source:. Section of Mammalian Transgenesis Center for Genetic Analysis of Behavior, National Institute for ... to the WDB/Nips strain. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain ... Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive ...

... both a pgdx single mutant and a pgdx/hktE double mutant of Hib were assayed for virulence in an infant rat model. The ability ... of both mutant strains to cause bacteremia was unaffected. Catalase (HktE) and a sole peroxidase (PGdx) account for the ... However, Haemophilus influenzae type b strain Eagan (Hib), a causative agent of bacterial sepsis and meningitis in young ... Finally, H2O2-scavenging is not a determinant of Hib virulence in the infant rat model of infection. ...

To create a chimaera, researchers inject stem cells from one organism into a mutant strain of a different organism. For example ... After the treatment, the mouse embryo began to develop a rat pancreas. ... After the treatment, the mouse embryo began to develop a rat pancreas. ... in one previous experiment, researchers injected rat stem cells into the embryo of a mouse that lacked the ability to grow a ...

Rats, WistarRats, Inbred WKYRats, Inbred SHRRats, Inbred StrainsRats, Inbred WFRats, Mutant StrainsRats, GunnRats, Inbred BB ... Rats, Mutant Strains. Rats bearing mutant genes which are phenotypically expressed in the animals.. ... Rats, WistarRats, Inbred WKYDisease Models, AnimalRats, Inbred SHRRats, Inbred StrainsBody WeightRandom AllocationPlant ... Rats, Inbred WF. Rats, Inbred WF are a strain of laboratory rats that are commonly used in medical research due to their ...

Rats, Mutant Strains. Rats bearing mutant genes which are phenotypically expressed in the animals.. ... 3-Diketogulonic AcidOxidation-ReductionRats, Mutant StrainsFree Radical ScavengersGlutathionePhosphorous AcidsIronPicrates ... Carcinogenesis Bioassay of L-Ascorbic Acid (Vitamin C) (CASRN 50-81-7) in F344/N Rats and B6C3F1 Mice (Feed Study) .... ... Thus the effect of paraquat on glial cells was examined using rat C6 glioma cells as a model system. Paraquat reduced cell ...

Rats, Wistar. *Rats, Mutant Strains. *Rats. *Ranviers Nodes. *Protein Subunits. *Precipitin Tests ... We herein demonstrate that Kv3.1b subunits are present at nodes of Ranvier in the CNS of both rats and mice. Kv3.1b colocalizes ... Moreover, in myelin-deficient rats, which have severe CNS dysmyelination, node-like clusters of Kv3.1b and Na+ channels are ... 4-Aminopyridine, a K+ channel blocker, broadened the compound action potential recorded from adult rat optic nerve and spinal ...

Using PAI deletion mutants in a rat model of pneumonia, Phillips-Houlbracq et al. related pneumonia pathogenicity to the ... B2 phylogroup strains were more sensitive to antimicrobials (resistance score 1.5 [0-4]) than were non-B2 phylogroup strains ( ... Characteristics of Other E. coli Strain Collections. To learn more about E. coli pneumonia strains, we compared the isolates ... We identified the O-type of 163 strains. We identified B2 phylogroup strains at the clonal level as having a combination of ...

We are using a zebrafish model of Duchenne muscular dystrophy (the dmd mutant strain) to investigate the developmental biology ... David Macks lab (https://iscrm.uw.edu/faculty/david-l-mack/) and their human iPSC and rat models of DMD. The long-term goal of ... David Macks lab (https://iscrm.uw.edu/faculty/david-l-mack/) to take advantage of human iPSC and rat models of DMD. ...

Ratsputin (Tech-Seer of the Rat-men). Str: 9 Dex: 16 Mutant Animal: Rat. Con: 13 Int: 17 Alignment: Chaotic. Will: 17 Cha: 14 ... Seems like some Rat-men have taken over a mine that the party seeks to recapture, the party has even allied with some mutant ... May have other hi-tech gear depending on the needs of the Mutant Lord. Ratsputin is a nasty, cunning and vicious rat- man, and ... Mutant Future (252) NeonLords (3) New Jericho (1) Night Below (1) OSE (7) Other Dust (10) Other Stuff (92) Pathfinder (49) ...

In a published study, vigabatrin (300 or 450 mg/kg) was administered by intraperitoneal injection to a mutant mouse strain on a ... In the rat and dog, vacuolation was reversible following discontinuation of vigabatrin treatment, but, in the rat, pathologic ... Vigabatrin showed no carcinogenic potential in mouse or rat when given in the diet at doses up to 150 mg/kg/day for 18 months ( ... The no-effect dose for adverse effects on embryo-fetal development in rats (50 mg/kg/day) is approximately 1/5 the MRHD on a mg ...

The number of rat strains is also increasing exponentially. These mouse and rat mutants are a tremendous genetic resource; ... to bring a level of genetic quality assurance into the scientific interchange and use of mouse and rat genetically mutant ... that have been entered into the International Mouse Strain Resource Center (IMSR) from laboratories and repositories all over ... there is the potential to generate over 200,000 mutant mouse strains between existing mouse strains (over 24,000) and ...