Radioimmunotherapy - Wikipedia
Radioimmunotherapy of leukemia. Adv Pharmacol. 2004;51:185-208. Quang TS, Brady LW. Radioimmunotherapy as a novel treatment ... Radioimmunotherapy (RIT) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. It is a ... Radioimmunotherapy of prostate cancer. Q J Nucl Med Mol Imaging. 2004 Dec;48(4):297-304. Dadachova E, Nosanchuk JD, Shi L, ... A set of radioimmunotherapy drugs that rely upon an alpha-emitting isotope (e.g., bismuth-213 or, preferably, actinium-225), ...
Dynamics of an Antitumour Model with Pulsed Radioimmunotherapy
... and the results indicate that radioimmunotherapy is more effective than either radiotherapy or immunotherapy alone. ... Dynamics of an Antitumour Model with Pulsed Radioimmunotherapy. Gang Wang. ,1Ming Yi. ,2and Sanyi Tang. 3 ... Numerous studies have shown that radioimmunotherapy is more effective for inhibiting tumour growth than radiotherapy [4, 20]. ... are determined through numerical simulations, and the results indicate that radioimmunotherapy is more effective than either ...
Frontiers | Editorial: Radioimmunotherapy-Translational Opportunities and Challenges
... named in this special issue radioimmunotherapy. However, one has always to keep in mind that many challenges do still exist ... Editorial: Radioimmunotherapy-Translational Opportunities and Challenges. Udo S. Gaipl1* Gabriele Multhoff2 A. Graham Pockley3 ... Immune modulatory effects of radiotherapy as basis for well-reasoned radioimmunotherapies. Strahlenther Onkol. (2018) 194:509- ... This again high lights the huge translational opportunities of radioimmunotherapies (Palata et al.). Besides cytokines, active ...
Health Canada approves new targeted radioimmunotherapy
Health Canada has approved a new treatment that could offer hope for those who suffer from what is considered an incurable form of non-Hodgkins lymphoma (NHL) and who have failed on, or relapsed following, other treatments. Health Canada approved Bexxar(TM) (tositumomab and iodine I 131 tositumomab) therapy for the treatment of patients with CD20 positive relapsed or
Dose Escalation and Dosimetry of First-in-Human α Radioimmunotherapy with 212Pb-TCMC-Trastuzumab | Journal of Nuclear Medicine
Intraperitoneal radioimmunotherapy of ovarian cancer with 177Lu-CC49: a phase I/II study. Gynecol Oncol. 1997;65:94-101. ... Dose Escalation and Dosimetry of First-in-Human α Radioimmunotherapy with 212Pb-TCMC-Trastuzumab. Ruby Meredith, Julien Torgue ... Intracavitary radioimmunotherapy to treat solid tumors. Cancer Biother Radiopharm. 2008;23:92-107. ... A strategy to reduce red marrow dose for intraperitoneal radioimmunotherapy. Clin Cancer Res. 1999;5:3044s-3047s. ...
A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection - Physiome...
Radioimmunotherapy (RIT) is a treatment for cancer which combines radiation and immune therapy using monoclonal antibodies. RIT ... A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection, Aiden A. ... A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection ... A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection ...
Radioimmunotherapy of experimental ovarian cancer with Astatine-211. An in vivo model for consolidation treatment in women
Follicular Lymphoma: Practice Essentials, Etiology and Pathophysiology, Epidemiology
Targeted Radioimmunotherapy. Follicular lymphoma is inherently radiosensitive, so the development of targeted ... Other first-line treatment options include rituximab, alone or in combination with other agents, and radioimmunotherapy ... Combination treatment with involved-field radiation therapy (IFRT) and chemotherapy (see below) and/or radioimmunotherapy is ... What is the role of targeted radioimmunotherapy in the treatment of follicular lymphoma? ...
Radioimmunotherapy in brain tumors
... Grana, Chiara Maria. Primo. ;Paganelli, Giovanni. Ultimo. 2013. Abstract. Gliomas and ... trials in brain tumors have almost exclusively exploited the potential of radioimmunotherapy (RIT) by employing a radiolabeled ... trials in brain tumors have almost exclusively exploited the potential of radioimmunotherapy (RIT) by employing a radiolabeled ...
Follicular Lymphoma: Practice Essentials, Etiology and Pathophysiology, Epidemiology
Targeted Radioimmunotherapy. Follicular lymphoma is inherently radiosensitive, so the development of targeted ... Other first-line treatment options include rituximab, alone or in combination with other agents, and radioimmunotherapy ... Combination treatment with involved-field radiation therapy (IFRT) and chemotherapy (see below) and/or radioimmunotherapy is ... What is the role of targeted radioimmunotherapy in the treatment of follicular lymphoma? ...
Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on...
Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on ... Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on ... Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on ...
89Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following α- and β-particle...
We aim to expedite the clinical translation of the developed radioimmunotherapy approaches by investigating the early ... Methods: Mice bearing BxPC3 tumor xenografts were treated with α- and β-particle pretargeted radioimmunotherapy (PRIT), ... DNA damage, PET, Radioimmunotherapy, pancreatic cancer, γH2AX, Alpha Particles, Animals, Antigens, Tumor-Associated, ... We aim to expedite the clinical translation of the developed radioimmunotherapy approaches by investigating the early ...
PARP Theranostic Auger Emitters Are Cytotoxic in BRCA Mutant Ovarian Cancer and Viable Tumors from Ovarian Cancer Patients...
Theranostics News, Research
Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model A new nuclear medicine therapy can cure human non-Hodgkin ...
Radioimmunotherapy with an <sup>211</sup>At-labeled anti-tissue factor antibody protected by sodium...
Radioimmunotherapy with an 211At-labeled anti-tissue factor antibody protected by sodium ascorbate. In: Cancer Science. 2021 ; ... Radioimmunotherapy with an 211At-labeled anti-tissue factor antibody protected by sodium ascorbate. Cancer Science. 2021 May; ... Radioimmunotherapy with an 211At-labeled anti-tissue factor antibody protected by sodium ascorbate. / Takashima, Hiroki; Koga, ... Radioimmunotherapy with an 211At-labeled anti-tissue factor antibody protected by sodium ascorbate. ...
Integrated Treatment Planning System To Calculate Three Dimensional Absorbed Dose For Radio-Immunotherapy | The Perk Lab
Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma |...
Combination radio-immunotherapy against 9464D-GD2 neuroblastoma tumors: some small tumors are cured, but not larger tumors. ... We recently described an effective combination radio-immunotherapy treatment regimen (combination adaptive-innate immunotherapy ... A combination radio-immunotherapy regimen (external beam radiotherapy, hu14.18-IL2 immunocytokine, CpG, anti-CD40, and anti- ... We previously described a combination radio-immunotherapy regimen (CAIR) that is effective in 9464D-GD2 tumors (figure 1A).4 We ...
Ragnar Hultborn | University of Gothenburg
Radioimmunotherapy. Sofia Frost, Tom Bäck, Nicolas Chouin, Holger Jensen, Ragnar Hultborn, Lars Jacobsson, Sture Lindegren ... Repeated Intraperitoneal alpha-Radioimmunotherapy of Ovarian Cancer in Mice. Jörgen Elgqvist, Håkan Andersson, Holger Jensen, ... Intraperitoneal alpha-radioimmunotherapy in mice using different specific activities. Jörgen Elgqvist, Håkan Andersson, Elin ... Intraperitoneal alpha-radioimmunotherapy of ovarian cancer - pharmacokinetics and dosimetry of 211At-MX35 F(ab)2 in a phase I ...
Radiation Therapy: MedlinePlus
Radiation-induced tumor immune microenvironments and potential targets for combination therapy | Signal Transduction and...
Stapled liposomes enhance cross-priming of radio-immunotherapy. Adv. Mater. (Deerfield Beach, Fla.) 34, e2107161 (2022). ... FLT3L release by natural killer cells enhances response to radioimmunotherapy in preclinical models of HNSCC. Clin. Cancer Res. ... Metabolic homeostasis-regulated nanoparticles for antibody-independent cancer radio-immunotherapy. Adv. Mater. 34, e2207343 ( ... Metal-cyclic dinucleotide nanomodulator-stimulated STING signaling for strengthened radioimmunotherapy of large tumor. Small ( ...
Syndecan-1 antigen, a promising new target for triple-negative breast cancer immuno-PET and radioimmunotherapy. A preclinical...
0267: Potential of Bi-213-Pankomab for Radioimmuno- Therapy: in Vitro Cytotoxicity and Biodistribu- Tion in Mice with...
The role of p53 in combination radioimmunotherapy with <sup>64</sup>Cu- DOTA-cetuximab and cisplatin in a mouse model of...
Radioimmunotherapy studies in p53-positive HCT116 tumor-bearing mice, receiving either radioimmunotherapy alone or in ... Radioimmunotherapy studies in p53-positive HCT116 tumor-bearing mice, receiving either radioimmunotherapy alone or in ... Radioimmunotherapy studies in p53-positive HCT116 tumor-bearing mice, receiving either radioimmunotherapy alone or in ... Radioimmunotherapy studies in p53-positive HCT116 tumor-bearing mice, receiving either radioimmunotherapy alone or in ...
Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in...
Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in ... Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in ... MeSH]: Radioimmunotherapy. [DDC subject group]: DDC 610 / Medicine & health. License CC BY-NC 4.0 International. https:// ... of the entire treatment scheme consisting of induction chemoimmunotherapy followed by chemotherapy-free radioimmunotherapy (RIT ...
Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20<sup>+</sup> B-cell lymphoma: Long-term follow-up of a...
Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20+ B-cell lymphoma: Long-term follow-up of a phase 1/2 ... Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20+ B-cell lymphoma: Long-term follow-up of a phase 1/2 ... Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20+ B-cell lymphoma: Long-term follow-up of a phase 1/2 ... Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20+ B-cell lymphoma : Long-term follow-up of a phase 1/2 ...
Fractionated radioimmunotherapy with |sup|90|/sup|Y-clivatuzumab tetraxetan and low-dose gemcitabine is active in advanced...
... with improved efficacy at the higher radioimmunotherapy doses. Conclusions: Fractionated radioimmunotherapy with 90Y-hPAM4 and ... Fractionated radioimmunotherapy with 90Y-clivatuzumab tetraxetan and low-dose gemcitabine is active in advanced pancreatic ... 2012). Fractionated radioimmunotherapy with 90Y-clivatuzumab tetraxetan and low-dose gemcitabine is active in advanced ... 2012). Fractionated radioimmunotherapy with 90Y-clivatuzumab tetraxetan and low-dose gemcitabine is active in advanced ...