Abnormal Immune Mechanism in Allogeneic Radiation Chimeras | Science
Abnormal Immune Mechanism in Allogeneic Radiation Chimeras Message Subject. (Your Name) has forwarded a page to you from ... The allogeneic chimeras showed almost normal amounts of serumn antibody after a third injection of antigen but a relative ... Six to 8 months later these chimeras were injected with Salmonella typhi flagellar antigen, and the formation of antibodies ...http://science.sciencemag.org/content/149/3684/645
"Homograft reaction in mouse radiation chimeras. I. Indirect evidence " by G Doria
Doria, G, "Homograft reaction in mouse radiation chimeras. I. Indirect evidence for graft-anti-host activity." (1962). Subject ... Homograft reaction in mouse radiation chimeras. I. Indirect evidence for graft-anti-host activity. ...https://mouseion.jax.org/ssbb1962/275/
"Early lymphatic regeneration in thymectomized radiation chimeras." by H Balner and H Dersjant
Balner, H and Dersjant, H, "Early lymphatic regeneration in thymectomized radiation chimeras." (1964). Subject Strain ...https://mouseion.jax.org/ssbb1964/76/
"Enzyme activity of donor origin in mouse radiation chimeras." by R C. Hard, R C. Allen et al.
Hard, R C.; Allen, R C.; Moore, D J.; and Kullgren, B, "Enzyme activity of donor origin in mouse radiation chimeras." (1969). ... Biochemistry, Metabolism:, Organs:, Radiation:, Transplantation:, Genes: Es-2 - Serum esterase-2, Strains: RF (W), RFM ...https://mouseion.jax.org/ssbb1969/454/
Caspase-8 Serves Both Apoptotic and Nonapoptotic Roles | The Journal of Immunology
Generation of radiation chimera. BM cells (2 × 106 per recipient) harvested from the femora of Casp8F/+:Mx1-Cre and Casp8F/−Mx1 ... C and D, In vitro progenitor assay (CFU-C) of the hemopoietic progenitor levels in BM of pI-pC-injected radiation chimera. C, ... Further testing of the consequences of caspase-8 deletion in radiation chimera of wild-type and floxed mice showed that pI-pC ... Induced ubiquitous deletion of the caspase-8 gene compromises hemopoietic progenitor function: study of radiation chimera. A ...http://www.jimmunol.org/content/173/5/2976.long
Absence of Vasoactive Intestinal Peptide Expression in Hematopoietic Cells Enhances Th1 Polarization and Antiviral Immunity in...
WT radiation chimera generated more tetramer+ CD8 T cells than cultures of DC and T cells from WT→WT radiation chimeras (Fig. 6 ... we used C57BL/6 radiation chimeras engrafted with syngeneic VIP-KO or WT hematopoietic cells following myeloablative radiation ... Radiation chimeras and stem cell transplantation. On day −1, 8- to 10-wk-old male B6 CD45.1 congenic mice were irradiated with ... Radiation chimeras engrafted with hematopoietic cells from VIP-KO donors had enhanced primary and secondary Ag-specific ...http://www.jimmunol.org/content/187/2/1057.long
Enhancement of bone marrow allografts from nude mice into mismatched recipients by T cells void of graft-versus-host activity ...
MAT.; BONE MARROW CELLS; TRANSPLANTS; LYMPHOCYTES; BIOLOGICAL FUNCTIONS; GRAFT-HOST REACTION; LECTINS; MICE; RADIATION CHIMERAS ... 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. ... CHIMERAS; CONNECTIVE TISSUE CELLS; EXTERNAL IRRADIATION; FUNCTIONS; IRRADIATION; LEUKOCYTES; MAMMALS; MATERIALS; MOSAICISM; ...https://www.osti.gov/scitech/biblio/6703946
Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmentally controlled.
... defined by direct thymocyte-stromal cell interactions was correlated with T cell development in situ using radiation and ... nonradiation chimeras of Thy-1.1/1.2 congenic mice. The results identify associ ... thymocyte-stromal cell interactions was correlated with T cell development in situ using radiation and nonradiation chimeras of ...http://www.biomedsearch.com/nih/Seeding-thymic-microenvironments-defined-by/3496419.html
Bone Marrow Radiation Chimeras Establish the Essential Role of the IEL GLP-1R for Control of Intestinal Gene Expression. ... Generation of Bone Marrow Chimeras. Bone marrow chimeras were generated by lethally irradiating Glp1r+/+ or Glp1r−/− female ...http://diabetes.diabetesjournals.org/content/64/7/2537
JCI - Lysosomal β-glucuronidase regulates Lyme and rheumatoid arthritis severity
Radiation chimera experiments revealed that resident joint cells drive arthritis susceptibility. C3H mice expressing WT Gusb. ...https://www.jci.org/articles/view/72339/pdf
Graft Versus Host Disease Medication: Immunosuppressive agents, Immunomodulating agents, Photoactive agents, Antineoplastic...
... as a syndrome called secondary disease to differentiate it from primary disease of radiation sickness. Mice that were given ... "Secondary disease" of radiation chimeras: a syndrome due to lymphoid aplasia. Ann N Y Acad Sci. 1962 Oct 24. 99:374-85. [ ...https://emedicine.medscape.com/article/429037-medication
Defective Phagocytosis and Clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow Transplantation | The Journal...
The origin of alveolar macrophages in mouse radiation chimeras. J. Exp. Med. 136:630. ...http://www.jimmunol.org/content/171/8/4416
The T Cell Receptor: Its Repertoire and Role in Thymocyte Development | SpringerLink
In a radiation chimera host H-2 antigens determine the immune responsiveness of donor cytotoxic cells. Nature 269:417, (1977). ...https://link.springer.com/chapter/10.1007/978-1-4684-5323-2_1
Amplification of Autoimmune Response through Induction of Dendritic Cell Maturation in Inflamed Tissues | The Journal of...
Radiation bone marrow chimera. NOD.MIP-GFP.Rag2−/− or NOD.Rag2−/− received 1300 rad of total body radiation in two doses ∼20 h ... Next, we generated radiation bone marrow chimeras to determine whether the presence of the GFP in intra-islet DCs was due to ... C, Sample flow cytometric profile of GFP signal in intra-islet DCs in radiation bone marrow chimeras is shown. The donor- ... into NOD.Rag2−/−.MIP-GFP chimeras (n = 4), and NOD.MIP-GFP into NOD.Rag2−/− chimeras (n = 6). Error bars represent SDs. E, ...http://www.jimmunol.org/content/182/5/2590.long
Joseph Brain | Harvard Catalyst Profiles | Harvard Catalyst
The origin of alveolar macrophages in mouse radiation chimeras. J Exp Med. 1972 Sep 01; 136(3):630-43. PMID: 4559194; PMCID: ...https://connects.catalyst.harvard.edu/Profiles/display/Person/38341
Stem Cells, Nonproliferating Cells, and Their Kinetics in Normal and Neoplastic Tissues | SpringerLink
Thomas, D., 1973, The radiation chimera as an experimental model for the study of haemopoietic stem Cell. populations, in: ... Repair of radiation damage as a factor in preoperative radiation therapy, in: The Interrelationship of Surgery and Radiation ... Hofer, K. G., 1970, Radiation effect on death and migration of tumor cells in mice, Radiat. Res. 43:663.PubMedGoogle Scholar ... Little, J. B., Hahn, G. M., Frindel, E., and Tubiana, M., 1973, Repair of potentially lethal radiation damage in vitro and in ...https://link.springer.com/chapter/10.1007/978-1-4684-2739-4_9
"Viral abrogation of stem cell transplantation tolerance causes graft r" by Daron Forman, Raymond M. Welsh et al.
Radiation Chimera; Receptors, Antigen, T-Cell, alpha-beta; Skin Transplantation; T-Lymphocyte Subsets; Time Factors; ...https://escholarship.umassmed.edu/gsbs_sp/299/
Table of Contents | Cancer Research
Autologous T Cells Control B-Chronic Lymphocytic Leukemia Tumor Progression in Human→Mouse Radiation Chimera ... Amelioration of Radiation-induced Liver Damage in Partially Hepatectomized Rats by Hepatocyte Transplantation ...http://cancerres.aacrjournals.org/content/59/23
MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation | The Journal of Immunology
Radiation chimeras demonstrated that MCPIP1 in nonhematopoietic cells is responsible for controlling skin pathology. Moreover, ...http://www.jimmunol.org/content/early/2016/12/02/jimmunol.1601551
Microbiome and Diseases: Graft-Versus-Host Disease | Springer for Research & Development
Mitigation of secondary disease of allogeneic mouse radiation chimeras by modification of the intestinal microflora. Journal of ...https://rd.springer.com/chapter/10.1007%2F978-3-319-90545-7_13
Natural, genetically determined resistance toward influenza virus in hemopoietic mouse chimeras. Role of mononuclear phagocytes...
Radiation chimeras produced by crosswise transfers of bone-marrow cell among histocompatible mice susceptible, or genetically ... Thus, inborn resistance of radiation chimeras was found to be independent of Mx-gene expression in cells of the hemopoietic ... 49 chimeras were tested individually, both of resistance of their macrophages to in vitro challenge with M-TUR (a strain of ... Natural, genetically determined resistance toward influenza virus in hemopoietic mouse chimeras. Role of mononuclear phagocytes ...http://jem.rupress.org/content/150/1/117
Systemic CD4+ T Cell Loss Resulting from Intravaginal H | Open-i
Radiation Chimera. *Species Specificity. *Tenofovir. *Thymus Gland/transplantation. *Transplantation, Heterologous. Related in ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2194746_pmed.0050016.g003&req=4
Secreted Lymphotoxin-α Is Essential for the Control of an Intracellular Bacterial Infection | JEM
Generation of Radiation Bone Marrow Chimeras.. Radiation bone marrow chimeric mice were generated as in Riminton et al. (17). ... chimeras were equivalent to those of WT chimeras, but in LTα−/− chimeras, granuloma formation was abnormal. LTα−/− chimeras ... Lane 1, WT chimera; lane 2, LTα−/− chimera; lane 3, LTβ−/− chimera; lane 4, WT control. β-actin PCR product, 304 bases; TNF PCR ... of WT chimeras (□), LTα−/− chimeras (○), and LTβ−/− chimeras (•) were determined over time. The data represent the means and SD ...http://jem.rupress.org/content/193/2/239
Connexin43 Is Dispensable for Phagocytosis | The Journal of Immunology
The most extensive of these studies involve the use of radiation chimeras to produce mice that lack Cx43 in cells of ... Generation of radiation chimeric mice. Radiation chimeric mice were generated as previously described (4). Cx43+/− mice on a ... Bone marrow-derived macrophages from radiation chimeric mice reconstituted with fetal liver cells from WT and Cx43−/− mice are ... In the model system used in this study, pluripotent cells derived from fetal livers or bone marrow harvested from radiation ...http://www.jimmunol.org/content/190/9/4830
I. Genetic studies of mouse serum protein types. II. Molecular hybridization of sheep hemoglobins - CaltechTHESIS
Using these three serum variants as markers, the sera of homologous radiation chimeras were examined for donor type proteins. ...https://thesis.library.caltech.edu/2765/