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*  Mechanism of action of hammerhead ribozymes and their applications in vivo: rapid identification of functional genes in the...
Moreover, vector-based siRNA (short-interfering RNA for RNA interference, RNAi) can also be used for the creation of the ... that many target sites on the RNA were previously inaccessible to cleavage owing to secondary and/or tertiary structure ... by coupling the site-specific cleavage activity of a hammerhead ribozyme with the unwinding activity of an endogenous RNA ...
  http://www.biochemsoctrans.org/content/30/6/1145
*  MED8 - Mediator of RNA polymerase II transcription subunit 8 - Homo sapiens (Human) - MED8 gene & protein
Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II ... a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. ... interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA ... Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens ...
  http://www.uniprot.org/uniprot/Q96G25
*  Long non-coding RNA - Wikipedia
Ogawa Y, Sun BK, Lee JT (June 2008). "Intersection of the RNA interference and X-inactivation pathways". Science. 320 (5881): ... short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs. However ... an ncRNA repressor of RNA polymerase II transcription". RNA. 13 (4): 583-96. doi:10.1261/rna.310307. PMC 1831867 . PMID ... Yang S, Tutton S, Pierce E, Yoon K (November 2001). "Specific double-stranded RNA interference in undifferentiated mouse ...
  https://en.wikipedia.org/wiki/Long_non-coding_RNA
*  Antisense RNA - Wikipedia
Kole R, Krainer AR, Altman S (January 2012). "RNA therapeutics: beyond RNA interference and antisense oligonucleotides". Nature ... RNA I and RNA II forms a duplex which introduces a conformational change of RNA II. Consequently, RNA II cannot hybridize with ... RNA-RNA interactions either in nucleus or cytoplasm and RNA-protein interactions (epigenetic). Antisense RNAs can be ... The replication of ColE1 relies on the transcription of a primer RNA named RNA II. Once RNA II is transcribed, it hybridizes to ...
  https://en.wikipedia.org/wiki/Antisense_RNA
*  rna interference
... (RNAi) is a post-transcriptional gene silencing method reproducing a naturally occurring phenomena. RNAi is ... RNA interference (RNAi) is a post-transcriptional gene silencing method reproducing a naturally occurring phenomena. RNAi is ... short interfering RNAs (siRNAs). These native siRNA duplexes are then incorporated into a protein complex called RNA-induced ... short interfering RNAs (siRNAs). These native siRNA duplexes are then incorporated into a protein complex called RNA-induced ...
  https://www.ebi.ac.uk/ols/ontologies/mi/terms?obo_id=MI%3A0256
*  Rna Interference | Encyclopedia.com
... of some of a cell's messenger RNA (mRNA) sequences is prevented, because of the presence of (and consequent destruction of) ... RNA Interference RNA interference [1] is a process in which translation ... RNA Interference Genetics Copyright Genetics Society of America. RNA Interference. RNA interference is a process in which ... Research Uses of RNA Interference. Because of its ability to turn off individual gene expression, RNA interference provides a ...
  https://www.encyclopedia.com/science-and-technology/biology-and-genetics/genetics-and-genetic-engineering/rna-interference
*  DNA-directed RNA interference - Wikipedia
Any RNA, including endogenous mRNAs or viral RNAs, can be silenced by designing constructs to express double-stranded RNA ... DNA-directed RNA interference (ddRNAi) is a gene-silencing technique that utilizes DNA constructs to activate an animal cell's ... Zou, W.; Song, Z.; Guo, Q.; Liu, C.; Zhang, Z.; Zhang, Y. (2011). "Intrathecal Lentiviral-Mediated RNA Interference Targeting ... endogenous RNA interference (RNAi) pathways. DNA constructs are designed to express self-complementary double-stranded RNAs, ...
  https://en.wikipedia.org/wiki/DNA-directed_RNA_interference
*  Wiley: RNA Interference (RNAi) - Wiley
Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit ... Overview of Gene Silencing by RNA Interference. Current Protocols in Nucleic Acid Chemistry. Daniel H. Kim, John J. Rossi ... Overview of Gene Silencing by RNA Interference Current Protocols in Nucleic Acid Chemistry. Daniel H. Kim, John J. Rossi ... Small Silencing RNAs and Gene Therapy eLS. Dirk Grimm. RNAi Screening: New Approaches, Understandings, and Organisms WIREs RNA ...
  http://www.wiley.com/WileyCDA/WileyTitle/productCd-1118829441.html
*  RNA interference - Wikiversity
RNA Interference, Springer: 1-19. *↑ Elbashir, S. M., et al. (2001). "Duplexes of 21-nucleotide RNAs mediate RNA interference ... RNA Interference, InTech *↑ Singh, D., et al. (2016). RNA Interference Technology-Applications and Limitations. RNA ... Short review: RNA interference in cells[edit]. Figure 2. Cells can trim double stranded RNA to form small inhibitory RNA (siRNA ... most siRNAs are generated by RNA-dependent RNA polymerase [1]. Single strand RNA transcripts: ssRNA. RNA interference requires ...
  https://en.wikiversity.org/wiki/RNA_interference
*  RNA Interference - October 1, 2004
RNA interference (RNAI) is now the "it" technology for drug development. RNAI works by destroying strands of messenger RNA ...
  http://money.cnn.com/magazines/business2/business2_archive/2004/10/01/8186670/index.htm
*  RNA Interference and Plant Defenses | Science
Thank you for your interest in spreading the word about Science.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
  http://science.sciencemag.org/content/321/5891/888.8
*  Pioneers of RNA interference win Nobel prize | New Scientist
Pioneers of RNA interference win Nobel prize. QUICK off the mark or what? It's less than 10 years since the latest winners of ... RNA interference (RNAi), as the technique is known, has revolutionised molecular biology. ... "They were the first to really describe the fact that this was a double-stranded RNA mediated phenomenon," says John Rossi of ... the medicine Nobel discovered how to "silence" genes with RNA. Now they are walking away with gold medals and a share of & ...
  https://www.newscientist.com/article/mg19225722.700-pioneers-of-rna-interference-win-nobel-prize/
*  Modeling Recursive RNA Interference
... such genes has been to use RNA interference to turn off potential RNA interference genes and to ask whether RNA interference ... The results show that RNA interference cannot turn itself off if the RNA interference pathway is too effective to start with, ... The goal of our report is to ask how it is possible for RNA interference to turn itself off, using a mathematical model of the ... This has become a powerful tool because a researcher can use RNA interference to turn off any gene of interest in order to test ...
  http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000183
*  Patenting RNA Interference Technology - Law360
Law360 (May 10, 2005, 12:00 AM EDT) -- RNA interference technology initiates degradation of specific messenger RNA (mRNA) and ... Patenting RNA Interference Technology. By Marius Meland May 10, 2005, 12:00 AM EDT ... As with all patent applications, the company must demonstrate that its RNA interference technology has utility, is adequately ...
  https://www.law360.com/articles/3425/patenting-rna-interference-technology
*  Structural insights into RNA interference. - PubMed - NCBI
Structural insights into RNA interference.. Sashital DG1, Doudna JA.. Author information. 1. Department of Molecular and Cell ... in understanding how regulatory RNAs are produced and how they trigger specific destruction of mRNAs during RNA interference ( ... forming a rigid RNA-binding platform that causes a sharp kink in the dsRNA target. The RNA binding surfaces on the dsRBDs are ... d) Alternatively, the 22 bp RNA can be modeled to stretch between the two PAZ domains of Dicer and Ago, each of which could ...
  https://www.ncbi.nlm.nih.gov/pubmed/20053548
*  Phys.org - rna interference
Two types of small RNA molecules - microRNA (miRNA) and small interfering RNA (siRNA) - are central to RNA interference. RNAs ... RNA interference. RNA interference (RNAi) is a system within living cells that helps to control which genes are active and how ... for example by preventing a messenger RNA from producing a protein. RNA interference has an important role in defending cells ... In 2006, Andrew Fire and Craig C. Mello shared the Nobel Prize in Physiology or Medicine for their work on RNA interference in ...
  https://phys.org/tags/rna+interference/sort/rank/1d/
*  RNA interference | EPICOS
Sign up for our free newsletters and receive twice a week news and intelligence regarding the Aerospace & Defence Industry, meticulously selected by our editorial team ...
  http://www.epicos.com/tags/rna-interference
*  RNAiMonitor - RNA Interference Assay
This RNA interference assay uses chemiluminescence to quantify RNAi target knockdown. No cell lysis is required; the RNAi assay ... RNAiMonitor-RNA Interference Assay. This RNA intereference assay is designed to monitor knockdown of RNAi target sequences ... RNA interference assay uses luciferase to monitor efficacy of shRNA or siRNA knockdown *Easy, no-cell-lysis protocol *Reporter ... RNA interference assay, measures shRNA or siRNA knockdown. Additional Information. Please see the product's Certificate of ...
  http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/RNA_Interference/MicroRNA/RNAi_Monitor?sitex=10020:22372:US&PROD=TH08EzAfQJ1vLgJ6HD-QQB_P:S&PROD_pses=ZG2D39FDBD936298790CCA5413BB52236E6C2977BCA9D4C5BE8F050C50DFA4043B88A5421713249B3FE63465532623DB4AB5D73B4A7766E607
*  Novel Gene Tool May Best RNA Interference Technique
Unlike conventional RNA interference techniques, CRISPR interference allows any number of individual genes to be silenced at ... "The horse has already left the barn with RNA interference, in the sense that the RNA message already has been transcribed from ... Another methodology, RNA interference, blocks the messenger RNA that drives protein protection based on the blueprint contained ... "In addition, it acts more crisply, if you will, by not turning off untargeted genes the way RNA interference techniques do." ...
  https://www.genengnews.com/topics/omics/novel-gene-tool-may-best-rna-interference-technique/
*  Viral vector-mediated RNA interference.
Abstract RNA interference (RNAi) is a powerful gene silencing mechanism that if properly harnessed has the potential to ... Abstract RNA interference (RNAi) is a powerful gene silencing mechanism that if properly harnessed has the potential to ... Delivery of inhibitory RNAs to target tissues needs to be safe, efficient, and for many diseases, long-lasting, in order to ...
  https://www.omicsonline.org/references/viral-vectormediated-rna-interference-1183560.html
*  Branched RNA: A New Architecture for RNA Interference
... and functional aspects of DNA and RNA research. ... Branched RNA: A New Architecture for RNA Interference. Anna ... N. Abe, H. Abe, and Y. Ito, "Dumbbell-shaped nanocircular RNAs for RNA interference," Journal of the American Chemical Society ... D. A. Braasch, S. Jensen, Y. Liu et al., "RNA interference in mammalian cells by chemically-modified RNA," Biochemistry, vol. ... In order to prepare branched RNA for RNA interference, the potential steric hindrance of the branching unit with RISC must be ...
  https://www.hindawi.com/journals/jna/2011/586935/
*  RNA Interference in the Pathogenic Fungus Cryptococcus neoformans | Genetics
RNA interference, a process in which the presence of double-stranded RNA homologous to a gene of interest results in specific ... If the observed acapsular phenotype of CAP59i-1 resulted from RNA interference, the levels of CAP59 RNA in those cells should ... neoformans is double-stranded RNA interference (RNAi). In this process double-stranded RNA (dsRNA) induces the specific ... 2000 Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell Biol. 2: 70-75. ...
  http://www.genetics.org/content/160/2/463
*  RNA interference - Wikipedia
... are central to RNA interference. RNAs are the direct products of genes, and these small RNAs can bind to other specific ... RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing ... The table below shows different drugs using RNA interference and what their phases and status is in clinical trials. RNA ... Wall, NR; Shi, Y (October 25, 2003). "Small RNA: can RNA interference be exploited for therapy?". Lancet. 362: 1401-1403. doi: ...
  https://en.wikipedia.org/wiki/RNA_interference
*  RasiRNA - Wikipedia
RasiRNA is key to the regulatory mechanism of many organisms as part of the RNA interference pathway. Small RNAs guiding RNA ... Repeat associated small interfering RNA (rasiRNA) is a class of small RNA that is involved in the RNA interference (RNAi) ... RNA interference. Genes and Dev. 15: 485-490. Belgnaoui, S. M., R. G. Gosden, O J. Semmes, A. Haoudi. 2006. Human LINE-I ... RasiRNA are in fact Piwi-interacting RNAs (piRNAs), which are small RNA molecules that interact with Piwi proteins. Piwi ...
  https://en.wikipedia.org/wiki/RasiRNA