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*  Physical Quality of Life Index - Wikipedia
The Physical Quality of Life Index (PQLI) is an attempt to measure the quality of life or well-being of a country. The value is the average of three statistics: basic literacy rate, infant mortality, and life expectancy at age one, all equally weighted on a 0 to 100 scale.. It was developed for the Overseas Development Council in the mid-1970s by Morris David Morris, as one of a number of measures created due to dissatisfaction with the use of GNP as an indicator of development. PQLI might be regarded as an improvement but shares the general problems of measuring quality of life in a quantitative way. It has also been criticized because there is considerable overlap between infant mortality and life expectancy.[1]. The UN Human Development Index is a more widely used means of measuring well-being.. Steps to Calculate Physical Quality of ...
  https://en.wikipedia.org/wiki/Physical_quality-of-life_index
*  Does quality of life assessment in palliative care look like a complex screening program? | Health and Quality of Life Outcomes...
Palliative care aims to help patients and their families have a better QoL by preventing and treating symptoms related to the disease and to the treatment itself, and addressing patients' psychosocial and spiritual needs [1]. The QoL assessment in clinical practice is an important part of palliative care resulting in several advantages for patients in terms of: 1) problem identification [37]; 2) facilitating patient decision making; 3) monitoring for changes [23],and 4) facilitating communication [32].. Although many QoL measures have been developed specifically for palliative care [9], evidence about effective interventions focused on QoL assessment implemented in clinical practice is lacking [52].. Before undertaking a study for evaluating how an intervention focused on QoL assessment works in everyday practice, it is essential to define the intervention and its components.. In this article, we defined a clinical intervention focused on QoL assessment as a complex intervention because its ...
  https://hqlo.biomedcentral.com/articles/10.1186/1477-7525-11-7
*  A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Breast Cancer Progressing After First-Line...
The Functional Assessment of Cancer Therapy-Breast (FACT-B) is composed of 5 multi-item sections where participants responded to questions assessing symptoms (scale: 0-4; 0='not at all' and 4='very much'), as follows: physical well-being (PWB) (7 items, total score 0-28), social/family well-being (SWB) (7 items, total score 0-28), emotional well-being (EWB) (6 items, total score 0-24), functional well-being (FWB) (7 items, total score 0-28); and breast cancer score based on the additional concerns section of FACT-B (10 items, total score 0-40). The FACT-B Trial Outcomes Index (TOI) score=sum of PWB, FWB, and breast cancer score subscale scores (total score 0-96). The Functional Assessment of Cancer Therapy-General (FACT-G) total score=sum of PWB, SWB, EWB, and FWB subscales scores (total score 0-108). The FACT-B total score=sum of PWB, SWB, EWB, FWB, and breast cancer score subscales scores (total score 0-148). In all cases a higher value indicated a better perceived quality of ...
  https://clinicaltrials.gov/show/NCT01250379
*  HCV New Drugs: Superiority of Interferon-Free Regimens for Chronic Hepatitis C: The Effect on Health-Related Quality of Life...
Previous studies have shown that treatment-naïve HCV patients treated with RBV and IFN experience a significant PRO impairment.[13,14] In particular, the use of IFN causes substantial side effects, including debilitating ones such as severe depression, which, in turn, affect patients' ability to sustain treatment long enough to obtain a cure whether through medical discontinuation or through patients' nonadherence. The use of RBV also has been shown to decrease PROs during treatment. However, the PRO data in patients who are retreated after having experienced another course of treatment have not been reported. Therefore, the aim of this study was to evaluate PROs during treatment with and without the use of IFN in patients who participated in a prior study of an IFN-containing or an IFN-free DAA-based regimen and has not achieved SVR ...
  http://hepatitiscnewdrugs.blogspot.com/2017/02/superiority-of-interferon-free-regimens.html
*  Quality-of-Life Assessment of Patients Who Have Cancer of the Esophagus - Tabular View - ClinicalTrials.gov
OBJECTIVES: I. Test the psychometric, clinical, and cross cultural validity and reliability of the quality-of-life questionnaire EORTC-QLQ-C30 (version 3.0) in conjunction with the esophageal cancer-specific module EORTC QLQ-OES-24 in patients with esophageal cancer.. OUTLINE: This is a multicenter study. Patients are stratified by treatment (potentially curative vs purely palliative). Patients receiving potentially curative treatment are further stratified according to study treatment (esophagectomy alone vs esophagectomy plus adjuvant or neoadjuvant chemo/radiotherapy vs radical radiotherapy with or without chemotherapy). Patients receiving purely palliative treatment are further stratified according to study treatment (intubation/laser/ethanol injection vs palliative chemo/radiotherapy without endoscopic relief of dysphagia). Patients are administered two questionnaires: (1) The EORTC QLQ-C30 (version 3.0) is a 30-item questionnaire about patient ability to function, ...
  https://clinicaltrials.gov/ct2/show/record/NCT00003321
*  Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A:...
Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial. ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:93116
*  Ideal doses of IMRT defined to reduce treatment side effects for head and neck cancer - Redorbit
DENVER, Oct. 18 "" Results from a University of Pittsburgh study evaluating intensity modulated radiation therapy (IMRT) for head and neck cancer determined the ideal doses for lessening treatment side effects. The findings were presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver. "Despite major advances in chemotherapy and radiation for the treatment of head and neck cancers, many patients continue to suffer debilitating side effects that greatly impact their quality of life," said Dwight E. Heron, M.D., study co-author and associate professor of radiation oncology, University of Pittsburgh School of Medicine and director of radiation oncology, University of Pittsburgh Medical Center. "While these high-energy beams are targeted to the tumor site as precisely as possible, they often inadvertently injure healthy tissue that surrounds the tumor site, limiting the doses of radiation that can be used to ...
  http://www.redorbit.com/news/health/276099/ideal_doses_of_imrt_defined_to_reduce_treatment_side_effects/
*  Life Quality Index - Wikipedia
The Life Quality Index (LQI) is a compound social indicator of human welfare that reflects the expected length of life in good health and enhancement of the quality of life through access to income. The Life Quality Index combines two primary social indicators: the expectancy of healthy life at birth, E, and the real gross domestic product per person, G, corrected for purchasing power parity as appropriate. Both are widely available and accurate statistics. The three components of the Life Quality Index, G, E and K reflect three important human concerns: the creation of wealth, the duration of life in good health and the time available to enjoy life. The amount of life available to enjoy wealth acts as a multiplying factor upon the value of that wealth. Conversely, the amount of income one ...
  https://en.wikipedia.org/wiki/Life_Quality_Index
*  Acpuris Intensive Spot Treatment - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Acpuris Intensive Spot Treatment - Get up-to-date information on Acpuris Intensive Spot Treatment side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Acpuris Intensive Spot Treatment
  http://www.rxwiki.com/acpuris-intensive-spot-treatment
*  Pivotal Study of a Percutaneous Mitral Valve Repair System - Full Text View - ClinicalTrials.gov
The SF-36 is a multidimensional, patient-reported survey containing 36 questions on a 0-100 scale measuring physical (Physical Component Score PCS) & mental health status (Mental Component Score MCS) in relation to 8 health concepts: physical functioning, role limitations due to physical or emotional health, bodily pain, general health perceptions, vitality, social functioning, & general mental health. Responses to each of the SF-36 items are scored and expressed as a score on a 0-100 scale (0% in a domain represents the poorest possible QOL&100% indicates full QOL).Higher scores represent better self-perceived health.. The physical & mental functions were assessed by the Physical Component Summary (PCS) score & Mental Component Summary (MCS) score. Normal PCS and MCS scores vary depending on the demographics of the population studied. The PCS&MCS norms for 65-75 year old are 44 & 52, respectively while the norms for CHF population are 31 & 46, respectively. ...
  https://clinicaltrials.gov/ct2/show/NCT00209274?term=Endocarditis&lup_s=09%2F17%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
*  Pivotal Study of a Percutaneous Mitral Valve Repair System - Full Text View - ClinicalTrials.gov
The SF-36 is a multidimensional, patient-reported survey containing 36 questions on a 0-100 scale measuring physical (Physical Component Score PCS) & mental health status (Mental Component Score MCS) in relation to 8 health concepts: physical functioning, role limitations due to physical or emotional health, bodily pain, general health perceptions, vitality, social functioning, & general mental health. Responses to each of the SF-36 items are scored and expressed as a score on a 0-100 scale (0% in a domain represents the poorest possible QOL&100% indicates full QOL).Higher scores represent better self-perceived health.. The physical & mental functions were assessed by the Physical Component Summary (PCS) score & Mental Component Summary (MCS) score. Normal PCS and MCS scores vary depending on the demographics of the population studied. The PCS&MCS norms for 65-75 year old are 44 & 52, respectively while the norms for CHF population are 31 & 46, respectively. ...
  https://clinicaltrials.gov/show/NCT00209274
*  WHO | WHO Quality of Life-BREF (WHOQOL-BREF)
The World Health Organization Quality of Life (WHOQOL) project was initiated in 1991. The aim was to develop an international cross-culturally comparable quality of life assessment instrument. It assesses the individual's perceptions in the context of their culture and value systems, and their personal goals, standards and concerns. The WHOQOL instruments were developed collaboratively in a number of centres worldwide, and have been widely field-tested.. The WHOQOL-BREF instrument comprises 26 items, which measure the following broad domains: physical health, psychological health, social relationships, and environment. The WHOQOL-BREF is a shorter version of the original instrument that may be more convenient for use in large research studies or clinical trials.. For further information related to WHOQOL-BREF and to obtain permission to use this questionnaire, please send a message to WHOQOL@who.int ...
  http://www.who.int/substance_abuse/research_tools/whoqolbref/en/
*  Study of Nivolumab (BMS-936558) Plus Ipilimumab Compared With Ipilimumab Alone in the Treatment of Previously Untreated,...
Health-related QOL was measured by mean changes from baseline in the EORTC-QLQ-C30 global health status/quality of life composite scale and by mean changes from baseline in the remaining EORTC QLQ-C30 questionnaire, Version 3. The EORTC QLQ-C30 is a questionnaire developed to assess the QOL of cancer patients. The questionnaire is a 30-item tool covering multiple items, including 5 functional scales (physical, role, emotional, social, and cognitive); 3 symptom scales (fatigue, nausea and vomiting, and pain); a global health status/QOL scale; and 6 single items (dyspnea, insomnia, appetite loss, constipation, diarrhea, and financial difficulties). Scores for each item range from 0 to 100. A high score for a functional scale represents a high (healthy) level of functioning, and a high score for the global health status represents a high QOL. However, a high score for a symptom scale represents more severe symptoms ...
  https://clinicaltrials.gov/show/NCT01927419
*  Perceived stress is related to health-related quality of life in patients with chronic rhinosinuitis | Clinical and...
Chronic rhinosinusitis (CRS) is a common disorder with a significant impact on health-related quality of life (HRQL). Due to symptoms based diagnosis, disease severity is usually estimated using questionnaires which evaluate subjective scores on severity of symptoms and deterioration of HRQL, like Sino-Nasal Outcome Test-22 Questionnaire (SNOT-22). Objective severity staging is rather based on computerized tomography (CT) scores than on severity of inflammation. There is recent evidence that perceived stress has significant impact on asthma incidence and hospitalization, as well as on allergic rhinitis. As CRS is comorbidity of asthma and allergic rhinitis, we hypothesized that perceived stress may have impact on severity of CRS. The aim of the study is to correlate objective and subjective outcome measures with perceived stress. ...
  https://ctajournal.biomedcentral.com/articles/10.1186/2045-7022-3-S2-O13
*  Plus it
Results The median disease duration was 7.5 (range 1-26) years in the WG group, and the median total VDI score was 2.0 (range 0-7). Compared to controls,WG patients reported impaired HRQOL reflected by significantly lower SF-36 physical component summary scores (PCS) and mental component summary scores (MCS) (p , 0.001) and by significantly lower scores in 7 out of 8 SF-36 subscales (p ≤ 0.001). In theWG group, no statistically significant correlations were found between the different SF-36 scores and the total VDI score, number of organ systems affected by damage, disease duration, or number of WG relapses. Patients with organ failure or other major forms of damage did not report significantly lower HRQOL than less severely affected patients. ...
  http://www.jrheum.org/content/early/2010/07/29/jrheum.100167
*  Coronary Intervention Improves Disease Specific Health-Related Quality of Life but Not Individualised Quality of Life : A...
To explore potential response shift effects with different quality of life (QoL) instruments in cardiac patients undergoing coronary intervention. Study Design and Setting: Recalibration was assessed with the disease specific health-related quality of life (HRQL) instrument MacNew in combination with a then-test approach. Reconceptualisation and reprioritisation were assessed with the individualised QoL instrument SEIQoL-DW. Significant treatment effects were seen on the MacNew (global Delta: 0.6 +/- 1.1, p = 0.004) but not on the SEIQoL-DW (Delta: 3.3 +/- 16, p = 0.37) 6 months after coronary intervention. No recalibration effect was found on the MacNew then-test, while with the SEIQOL-DW potential response shift effects of reconceptualisation and reprioritisation were seen. For the first time response shift effects were explored in cardiac patients undergoing coronary intervention. This study confirmed that there is a clinically ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:438115
*  Developing the Vascular Quality of Life Questionnaire: a new disease-specific quality of life measure for use in lower limb...
The purpose of this study was to develop and validate an easily used disease-specific quality of life (QOL) measure for patients with chronic lower limb ischemia and to design an evaluative instrument, responsive to within-subject change, that adds t
  http://www.biomedsearch.com/nih/Developing-Vascular-Quality-Life-Questionnaire/11296317.html
*  NoExcuses: Prevalence of incontinence and incontinence-specific Quality of life impairment in women with cystic fibrosis.
AIMS: Cystic fibrosis (CF) is the commonest autosomal recessive disorder in Caucasians. With advancing medical technology, the life expectancy has more than double in the last twenty years. This has led to new unforeseen health problems like urinary incontinence. The aim was to establish the prevalence, symptomatic typology, and quality of life impact of incontinence in a population of women with CF. METHODS: Women were recruited from two London tertiary referral centres for CF. They were asked to fill in a self- completed anonymous King's Health Questionnaire (KHQ) for assessment of symptoms and quality of life Impairment. Their age was also noted. Descriptive statistics are reported. Correlation was assessed using Pearson's Product Moment Correlation Coefficient (r). RESULTS: One hundred and forty six women were approached for enrolment. 98(67%) consented to take part in study. Their mean age was 28. Seventy three (74%) ...
  http://noexcusesnoexcuses.blogspot.com/2009/05/prevalence-of-incontinence-and.html
*  Most recent papers with the keyword Patient quality of life outcomes following surgery | Read by QxMD
The objective of this study is to compare health-related quality of life (QOL) outcomes between radical prostatectomy (RP) and external beam radiation therapy (EBRT) for localized prostate cancer. PubMed, EMBASE, the Cochrane Library and Web of Science (to July 2017) were searched. Pooled analysis of each domain-specific score was calculated in relevant studies, and its change with follow-up time was explored by sub-group analysis. A total of six studies containing 4423 patients were included. Men underwent RP was associated with worse urinary and sexual domain score than EBRT (standardized mean difference (SMD) = -0 ...
  https://www.readbyqxmd.com/keyword/79390
*  Pulmonary function and health-related quality of life 1-year follow up after cardiac surgery
Background: Pulmonary function is severely reduced in the early period after cardiac surgery, and impairments have been described up to 4-6 months after surgery. Evaluation of pulmonary function in a longer perspective is lacking. In this prospective study pulmonary function and health-related quality of life were investigated 1 year after cardiac surgery.. Methods: Pulmonary function measurements, health-related quality of life (SF-36), dyspnoea, subjective breathing and coughing ability and pain were evaluated before and 1 year after surgery in 150 patients undergoing coronary artery bypass grafting, valve surgery or combined surgery.. Results: One year after surgery the forced vital capacity and forced expiratory volume in 1 s were significantly decreased (by 4-5 %) compared to preoperative values (p , 0.05). Saturation of peripheral oxygen was unchanged 1 year postoperatively compared to baseline. A significantly improved health-related ...
  http://oru.diva-portal.org/smash/record.jsf?pid=diva2:951060
*  The Effect of Diabetes Complications on Health-Related Quality of Life: The Importance of Longitudinal Data to Address Patient...
Alva, M. (2013). The Effect of Diabetes Complications on Health-Related Quality of Life: The Importance of Longitudinal Data to Address Patient Heterogenity. Health Economics, 23(4), 487 - 500. DOI: 10.1002/hec.2930 ...
  https://www.rti.org/publication/effect-diabetes-complications-health-related-quality-life-importance-longitudinal-data
*  Perfect Health Diet: Weight Loss Version - Perfect Health Diet | Perfect Health Diet
OK, here goes! I was told from my Dr to buy your book. After my bloodwork came back, she told me I had an infection in my body and this book would change my life. This was just less then 1 week ago. I read the book in one sitting, and was naturally very excited to get well. My back story…I have had HBP since the first time it was taken at age 18. I never weighed more than 130 pounds at 5'8″, so I never worried about what I ate, until I became toxemic with my first child at age 22. I read every label, making sure not to eat anything with added salt. At 27, I was on a beta blocker and taken off, because of my good work with eating no salt and exercise. I weighed 130-135 my whole life until I became extremely dehydrated, had thrush in my mouth and throat and was hospitalized at age 48. I was on medications, including attenolol with hctz, and was being treated for fibomalagia with soma and tramadol. Bloodwork and tests came back in the hospital that I had CKD, barely any vitamin ...
  http://perfecthealthdiet.com/2011/02/perfect-health-diet-weight-loss-version/comment-page-6/
*  Translation, cultural adaptation assessment, and both validity and reliability testing of the Kidney Disease Quality of Life -...
PAKPOUR, A. H., YEKANINEJAD, M., MOLSTED, S., HARRISON, A. P., HASHEMI, F. and SAFFARI, M. (2011), Translation, cultural adaptation assessment, and both validity and reliability testing of the Kidney Disease Quality of Life - Short Form version 1.3 for use with Iranian patients. Nephrology, 16: 106-112. doi: 10.1111/j.1440-1797.2010.01389.x ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1797.2010.01389.x/references