*  Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 antibody [4A11] (ab110025)
Mouse monoclonal Mitochondrial Pyruvate dehydrogenase kinase 1 antibody [4A11] validated for WB, ELISA, IHC, Flow Cyt, ICC/IF ... Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the ... Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 antibody [4A11]. See all Mitochondrial Pyruvate dehydrogenase kinase 1 ... Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 antibody [4A11] images. * Western blot - Anti-Mitochondrial Pyruvate ...
  http://www.abcam.com/mitochondrial-pyruvate-dehydrogenase-kinase-1-antibody-4a11-ab110025.html
*  KAKEN - Research Projects | Structure, Expression and Pathogenesis of Human Pyruvate Dehydrogenase Gene (KAKENHI-PROJECT...
Publications] Kichiko Koike: 'Chronic acidemia due to a pyruvate dehydrogenase deficiency in pyruvate dehydrogenase complex, ... Chronic acidemia due to pyruvate dehydrogenase deficiency in pyruvate dehydrogenase complex,with evidence of abnormalities of α ... Publications] Kichiko Koike: 'Chronic acidemia due to a pyruvate dehydrogenase complex,with abnormalities of the α and β ... Publications] Kichiko Koike: 'Chronic acidemia due to a pyruvate dehydrogenase complex,with abnormalities of the α and β ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01570163/
*  Effects of recombinant monokines on hepatic pyruvate dehydrogenase, pyruvate dehydrogenase kinase, lipogenesis de novo and...
... on the activation state of the hepatic pyruvate dehydrogenase complex (PDHa), the activity of mitochondrial PDH kinase, hepatic ... Effects of recombinant monokines on hepatic pyruvate dehydrogenase, pyruvate dehydrogenase kinase, lipogenesis de novo and ... Effects of recombinant monokines on hepatic pyruvate dehydrogenase, pyruvate dehydrogenase kinase, lipogenesis de novo and ... Effects of recombinant monokines on hepatic pyruvate dehydrogenase, pyruvate dehydrogenase kinase, lipogenesis de novo and ...
  http://www.biochemj.org/content/284/1/129
*  Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells |...
Integrating Bioinformatics and Physiology to Describe Genetic Effects in Complex Polygenic Diseases ... Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells. ... pyruvate dehydrogenase) kinase 1, a negative regulator of PDH, to metabolic coupling in 832/13 clonal beta-cells. Knockdown of ... glucose-stimulated cellular oxygen consumption and pyruvate-stimulated mitochondrial oxygen consumption increased 1.7- (P , ...
  https://www.ludc.lu.se/peter-spegel-associate-professor/publication/2dc3b368-04b2-4131-b6b1-02888c906fff
*  Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex superfamily
The SCOP classification for the Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex superfamily including the ... INHERITED FROM: pyruvate dehydrogenase complex ,, mitochondrial pyruvate dehydrogenase complex. Cellular Component (CC). ... pyruvate dehydrogenase complex ,, cytoplasmic part ,, mitochondrial pyruvate dehydrogenase complex. Cellular Component (CC). ... pyruvate dehydrogenase complex ,, cytoplasmic part ,, mitochondrial pyruvate dehydrogenase complex. Cellular Component (CC). ...
  http://supfam.cs.bris.ac.uk/SUPERFAMILY/cgi-bin/scop.cgi?ipid=SSF47005
*  Inactivation and disassembly of the pyruvate dehydrogenase multienzyme complex from bovine kidney by limited proteolysis with...
The lipoamide dehydrogenase and pyruvate dehydrogenase components, however, are not cleaved by the inactivase. ... However, the inactivation of the overall reaction does not affect any of the component activities of the enzyme complex. By ... are unable to catalyze the coordinated reaction sequence of pyruvate oxidation. The dissociation occurs as a consequence of ... Mammalian pyruvate dehydrogenase multienzyme complex is inactivated when treated with a leupeptin-sensitive enzyme (termed ' ...
  https://www.semanticscholar.org/paper/Inactivation-and-disassembly-of-the-pyruvate-dehyd-Kresze-Steber/032f1775aa844093b1357e47e1f23b228bf45a8e
*  AZD7545 is a selective inhibitor of pyruvate dehydrogenase kinase 2 | Biochemical Society Transactions
The PDH (pyruvate dehydrogenase) multi-enzyme complex catalyses a key regulatory step in oxidative glycolysis. Phosphorylation ... AZD7545 is a selective inhibitor of pyruvate dehydrogenase kinase 2. J.A. Morrell, J. Orme, R.J. Butlin, T.E. Roche, R.M. ... AZD7545 is a selective inhibitor of pyruvate dehydrogenase kinase 2. J.A. Morrell, J. Orme, R.J. Butlin, T.E. Roche, R.M. ... pyruvate dehydrogenase kinase (PDHK). Footnotes. *. 679th Meeting of the Biochemical Society held at the University of Essex, ...
  http://www.biochemsoctrans.org/content/31/6/1168
*  DLAT - Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor -...
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the ... "Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.". Kato M ... Part of the multimeric pyruvate dehydrogenase complex that contains multiple copies of pyruvate dehydrogenase (subunits PDH1A ... The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, and thereby links the ...
  http://www.uniprot.org/uniprot/P10515
*  dihydrolipoyl dehydrogenase - Creative Enzymes
A component of the multienzyme 2-oxo-acid dehydrogenase complexes. In the pyruvate dehydrogenase complex, it binds to the core ... A flavoprotein (FAD). A component of the multienzyme 2-oxo-acid dehydrogenase complexes. In the pyruvate dehydrogenase complex ... lipoate dehydrogenase; lipoic acid dehydrogenase; lipoyl dehydrogenase; protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase ... dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxidoreductase (NADH); ...
  https://www.creative-enzymes.com/product/Dihydrolipoyl-Dehydrogenase_11818.html
*  KEGG T01717: 100823294
... dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial-like (A) ... bdi:100823294 K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] , (RefSeq) ...
  http://www.genome.jp/dbget-bin/www_bget?-f+-n+a+bdi:100823294
*  Pyruvate dehydrogenase lipoamide kinase isozyme 1 - Wikipedia
... pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase complex ... It codes for an isozyme of pyruvate dehydrogenase kinase (PDK). Pyruvate dehydrogenase (PDH) is a part of a mitochondrial ... The Pyruvate Dehydrogenase (PDH) complex must be tightly regulated due to its central role in general metabolism. Within the ... "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells". The Journal of Biological ...
  https://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_lipoamide_kinase_isozyme_1
*  pyruvate dehydrogenase complex | Biochemical Journal
Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly ... Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation Nam Ho Jeoung, Pengfei Wu, ... Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat ... Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not ...
  http://www.biochemj.org/keyword/pyruvate-dehydrogenase-complex-0
*  RCSB PDB - 1IYU: LIPOYL DOMAIN OF PYRUVATE DEHYDROGENASE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE Macromolecule...
Three-dimensional structure in solution of the N-terminal lipoyl domain of the pyruvate dehydrogenase complex from Azotobacter ... DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX (1IYU:A) * Dihydrolipoyllysine Residue ...
  http://www.rcsb.org/pdb/explore/derivedData.do?structureId=1IYU
*  Dlat MGI Mouse Gene Detail - MGI:2385311 - dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. IPR036625 E3-binding ... PR:000006504 dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial. (term ... and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in ... pyruvate decarboxylase deficiency DOID:3649. ICD10CM:E74.4. MESH:D015325. NCI:C103968. OMIM:245348. OMIM:245349. OMIM:312170. ...
  http://www.informatics.jax.org/marker/MGI:2385311
*  Pyruvate dehydrogenase complex deficiency | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
... resources and questions answered by our Genetic and Rare Diseases Information Specialists for Pyruvate dehydrogenase complex ... Pyruvate dehydrogenase complex deficiency Title Other Names:. Pyruvate dehydrogenase deficiency; PDHC; PDH deficiency; Pyruvate ... These enzymes are part of a group of three enzymes called the pyruvate dehydrogenase complex. The pyruvate dehydrogenase ... The goal of the treatment for pyruvate dehydrogenase complex (PDC) deficiency is to stimulate the pyruvate dehydrogenase ...
  https://rarediseases.info.nih.gov/diseases/7513/disease
*  Pyruvate dehydrogenase complex - Wikipedia
Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called ... The reaction catalysed by pyruvate dehydrogenase complex is: Initially, pyruvate and thiamine pyrophosphate (TPP or vitamin B1 ... In eukaryotes PDC is tightly regulated by its own specific pyruvate dehydrogenase kinase (PDK) and pyruvate dehydrogenase ... "pyruvate dehydrogenase reaction" because it also involves the oxidation of pyruvate. This multi-enzyme complex is related ...
  https://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_complex
*  pdhC - Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - Mycoplasma mycoides subsp. capri LC str...
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation. ,p>Information which has been ... tr,F4MPG6,F4MPG6_MYCML Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex OS=Mycoplasma mycoides ... Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation. ,p>Information which has been generated by the UniProtKB ...
  http://www.uniprot.org/uniprot/F4MPG6
*  pdhC - Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex - Leifsonia xyli subsp. xyli ...
... pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). ... The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple ... The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple ... Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexAdd BLAST. 452. Amino acid ...
  http://www.uniprot.org/uniprot/Q6ABX9
*  Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly |...
... pyruvate dehydrogenase complex; hPDC, human PDC; PDK, pyruvate dehydrogenase kinase; rhE2/E3BP, recombinant human E2/E3BP; rhE3 ... Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly. ... Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly ... Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine ...
  http://www.biochemj.org/content/437/3/565
*  Recombinant Mouse Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial(Dlat...
Purchase Recombinant Mouse Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ... Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Pyruvate dehydrogenase complex component E2. ... The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the ... The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, and thereby links the ...
  https://www.cusabio.com/Recombinant-Protein/Recombinant-Mouse-Dihydrolipoyllysine-residue-acetyltransferase-component-of-pyruvate-dehydrogenase-complex-mitochondrialDlat-12556591.html
*  Gentaur Molecular :EIAab \ Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex,Lipoyl-containing...
Lipoyl-containing pyruvate dehydrogenase complex component X,Mouse,Mus musculus,Pdhx,Pyruvate dehydrogenase protein X c \ ... Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, ... Lipoamide dehydrogenase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex E3 component). [Dlst] ... Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex,Lipoyl-containing pyruvate dehydrogenase ...
  http://www.antibody-antibodies.com/product2880028-search-Dihydrolipoamide_dehydrogenase_binding_protein_of_pyruvate_dehydrogenase_complex,Lipoyl_containing_pyruvate_dehydrogenase_complex_component_X,Mouse,Mus_musculus,Pdhx,Pyruvate_dehydrogenase_protein_X_c.html
*  Engineering of Serine-Deamination pathway, Entner-Doudoroff pathway and pyruvate dehydrogenase complex to improve poly(3...
In E. coli, pyruvate is metabolized by the pyruvate dehydrogenase (PDH) complex and pyruvate oxidase during aerobic growth ... Quail MA, Haydon DJ, Guest JR: The pdhR-aceEF-lpd operon of Escherichia coli expresses the pyruvate dehydrogenase complex. Mol ... Escherichia coli poly(3-hydroxybutyrate)L-serine deaminateEntner-Doudoroff pathwayPyruvate dehydrogenase complex ... Overexpression of the pyruvate dehydrogenase complex for enhanced PHB production. ...
  https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-014-0172-6
*  Journal News section of ASBMB Today
The key enzyme complex bridging these two processes is known as the pyruvate dehydrogenase complex, or PDC, and is the subject ... Pyruvate dehydrogenase complex. Energy generation in prokaryotic and eukaryotic organisms is a highly efficient, multistep and ... To harness the full energy content of glucose, pyruvate undergoes further oxidation in the Krebs cycle, generating large ... Normally, glucose is metabolized initially via the glycolytic pathway, generating pyruvate and small amounts of ATP. ...
  https://www.asbmb.org/asbmbtoday/201408/JournalNews/
*  Nagendra Yadava, Ph.D. | Pioneer Valley Life Sciences Institute: A Baystate Medical Center & UMass Amherst Research Partnership
2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I ... specific inhibitors of the mitochondrial pyruvate carrier. Proc. Natl. Acad. Sci., 110(14):5422-7. ... Most often mitochondrial dysfunction is due to partial deficiencies of the respiratory chain complexes, with complex I (NADH: ... Thus, complex I is the main focus of our studies to elucidate the role of mitochondrial dysfunction in disease and the process ...
  http://pvlsi.org/node/17
*  Aminoethanesulfonic Acid Manufacturer, Supplier & Exporter from India
Boron trifluoride-acetic acid-complex *Boron trifluoride-dimethyl ether complex *Brilliant green (hydrogen sulfate) (C.I. 42040 ... Aldehyde dehydrogenase *1-Butyl-3-methylimidazolium hydrogensulfate *Butyric acid *Boron hydride-tert-butylamine ... CALCIUM PYRUVATE *CALCIUM PHOSPHATE monobasic *CALCIUM PHOSPHATE *CALCIUM PROPIONATE. *CALCIUM-D-SACCHARATE (tetrahydrate) ...
  http://www.alphachemikaindia.com/aminoethanesulfonic-acid-570936.html