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*  Native Bovine Pyruvate Carboxylase - Creative Enzymes
Pyruvate carboxylase is a mitochondrial protein that has a biotin prosthetic group that requ ... Pyruvate carboxylase catalyzes the carboxylation of pyruvate to oxaloacetate. ... Pyruvate carboxylase catalyzes the carboxylation of pyruvate to oxaloacetate. Pyruvate carboxylase is a mitochondrial protein ... The enzyme from Creative Enzymes has been used as a positive control during the assay of pyruvate carboxylase activity in cell- ...
  https://www.creative-enzymes.com/product/Native-Bovine-Pyruvate-Carboxylase_1428.html
*  RCSB PDB for 3BG9
Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer ... Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant. *DOI: ... Pyruvate carboxylase, mitochondrial A, B, C, D 718 Homo sapiens EC#: 6.4.1.1 IUBMB Fragment: CT+PT+BCCP Domain Mutation: F1077A ...
  http://www.rcsb.org/pdb/explore/geometryDisplay.do?structureId=3BG9
*  Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets. |...
Our results are consistent with the concept that anaplerosis via pyruvate carboxylase determines pyruvate cycling, which has ... Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.. ... The anaplerotic enzyme pyruvate carboxylase is highly expressed in beta cells, and anaplerosis influences insulin secretion in ... By inhibiting pyruvate carboxylase in rat islets, we aimed to clarify the hitherto unknown metabolic events underlying ...
  https://www.ludc.lu.se/erik-renstrom/publication/8f12a027-a3f5-4dc4-b142-007cb81d9f6a
*  mcb100ExamIIISolutions - GAP dehydrogenase - NADH b pyruvate carboxylase c biotin d carbon dioxide or bicarbonate 5 a phosphate...
GAP dehydrogenase - NADH b) pyruvate carboxylase c) biotin d) carbon dioxide or bicarbonate 5. a) phosphate + glycogen(n) ÅÆ ... Unformatted text preview: GAP dehydrogenase - NADH b) pyruvate carboxylase c) biotin d) carbon dioxide or bicarbonate 5. a) ... pyruvate carboxylase - ATP PEP carboxykinase - GTP 3-phosphoglcerate kinase - ATP ...
  https://www.coursehero.com/file/106786/mcb100ExamIIISolutions/
*  Fall 08 Exam 2 - e Phosphopentose isomerase a Pyruvate carboxylase b Pyruvate kinase c PEP carboxykinase d Glucose 6...
e. Phosphopentose isomerase a. Pyruvate carboxylase b. Pyruvate kinase c. PEP carboxykinase d. Glucose 6-phosphatase e. ... Unformatted text preview: e. Phosphopentose isomerase a. Pyruvate carboxylase b. Pyruvate kinase c. PEP carboxykinase d. ... Fall 08 Exam 2 - e Phosphopentose isomerase a Pyruvate.... This preview shows document pages 1 - 9. Sign up to view the full ...
  https://www.coursehero.com/file/5691303/Fall-08-Exam-2/
*  RCSB PDB - 4HNV: Crystal structure of R54E mutant of S. aureus Pyruvate carboxylase Structure Summary Page
Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis. ... Pyruvate carboxylase A, B, C, D 1173 Staphylococcus aureus EC#: 6.4.1.1 IUBMB Mutation: R54E Gene Name(s): pycA SAV1114 ... Crystal structure of R54E mutant of S. aureus Pyruvate carboxylase. *DOI: 10.2210/pdb4hnv/pdb ...
  http://www.rcsb.org/pdb/explore/explore.do?structureId=4HNV
*  The conversion of alanine into glutamine in guinea-pig renal cortex. Essential role of pyruvate carboxylase | Biochemical...
Essential role of pyruvate carboxylase. M Forissier, G Baverel. Biochemical Journal Oct 15, 1981, 200 (1) 27-33; DOI: 10.1042/ ... 7. In this pathway, the central role of pyruvate carboxylase, which explains the discrepancy between our results and those of ... pyruvate carboxylase and enzymes of the tricarboxylic acid cycle is proposed for the conversion of alanine into glutamine. 6. ... 3. At neither concentration of alanine was there accumulation of glucose, glycogen, pyruvate, lactate, aspartate or ...
  http://www.biochemj.org/content/200/1/27
*  Ligand-induced conformational transitions and secondary-structure composition of chicken liver pyruvate carboxylase |...
Secondary-structure composition of chicken liver pyruvate carboxylase estimated from the far-u.v. c.d. spectrum of the enzyme ... Ligand-induced conformational transitions and secondary-structure composition of chicken liver pyruvate carboxylase. Karen S. ... Apparent conformational transitions induced in chicken liver pyruvate carboxylase by substrates, KHCO3 and MgATP, and the ... Ligand-induced conformational transitions and secondary-structure composition of chicken liver pyruvate carboxylase ...
  http://www.biochemj.org/content/177/2/697
*  AOT91 26715 - Pyruvate carboxylase - Mycobacteroides sp. H092 - AOT91 26715 gene & protein
... carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the ... tr,A0A0R3EFE8,A0A0R3EFE8_9MYCO Pyruvate carboxylase OS=Mycobacteroides sp. H092 OX=1720573 GN=AOT91_26715 PE=4 SV=1 ... IPR003379 Carboxylase_cons_dom. IPR005479 CbamoylP_synth_lsu-like_ATP-bd. IPR016185 PreATP-grasp_dom_sf. IPR000891 PYR_CT. ... IPR003379 Carboxylase_cons_dom. IPR005479 CbamoylP_synth_lsu-like_ATP-bd. IPR016185 PreATP-grasp_dom_sf. IPR000891 PYR_CT. ...
  https://www.uniprot.org/uniprot/A0A0R3EFE8
*  Pyruvate carboxylase - Wikipedia
Pyruvate Carboxylase Symmetry Comparison Pyruvate carboxylase uses a covalently attached biotin cofactor which is used to ... During gluconeogenesis, pyruvate carboxylase is involved in the synthesis of phosphoenolpyruvate (PEP) from pyruvate. Pyruvate ... deficiency of pyruvate carboxylase can also lead to hypoglycemia. Pyruvate carboxylase deficiency PDB: 2QF7​; Jitrapakdee S, St ... A deficiency of pyruvate carboxylase can cause lactic acidosis as a result of lactate build up. Normally, excess pyruvate is ...
  https://en.wikipedia.org/wiki/Pyruvate_carboxylase
*  Pyruvate carboxylase deficiency - Wikipedia
Children with pyruvate carboxylase deficiency type A typically survive only into early childhood. Pyruvate carboxylase ... GeneReview/NCBI/NIH/UW entry on Pyruvate Carboxylase Deficiency Pyruvate carboxylase deficiency at NLM Genetics Home Reference ... Pyruvate carboxylase deficiency is an inherited disorder that causes lactic acid and to accumulate in the blood. High levels of ... Pyruvate carboxylase also plays a role in the formation of the protective sheath that surrounds certain nerve cells (myelin) ...
  https://en.wikipedia.org/wiki/Pyruvate_carboxylase_deficiency
*  RCSB PDB - 3BG3: Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N...
Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer ... pyruvate carboxylase f1077a mutant fold pyruvate carboxylase f1077a mutant domain B2. 3bg3B02. Alpha Beta Alpha-Beta Barrel TIM ... pyruvate carboxylase f1077a mutant fold pyruvate carboxylase f1077a mutant domain C2. 3bg3C02. Alpha Beta Alpha-Beta Barrel TIM ... Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus). ...
  http://www.rcsb.org/pdb/explore/derivedData.do?structureId=3BG3
*  Pyruvate carboxylase from Corynebacterium glutamicum: characterization, expression and inactivation of the pyc gene.
In addition to phosphoenolpyruvate carboxylase (PEPCx), pyruvate carboxylase (PCx) has recently been found as an anaplerotic ... Pyruvate carboxylase from Corynebacterium glutamicum: characterization, expression and inactivation of the pyc gene.. Peters- ... Pyruvate carboxylase from Corynebacterium glutamicum: characterization, expression and inactivation of the pyc gene. ... Peters-Wendisch, P., Kreutzer, C., Kalinowski, J., Pátek, M., Sahm, H., and Eikmanns, B. J. (1998). Pyruvate carboxylase from ...
  https://pub.uni-bielefeld.de/publication/1904807
*  pyruvate carboxylase deficiency | The Colleen Giblin Research Laboratories for Pediatric Neurology
Tag Archives: pyruvate carboxylase deficiency. Research. LABORATORY & CLINICAL RESEARCH:. Laboratory Research. a. Molecular ... pyruvate dehydrogenase deficiency and pyruvate carboxylase deficiency, among other mitochondrial disorders, were first ... The molecular genetics, pathogenesis and clinical forms of Pyruvate carboxylase deficiency.. *The natural history and therapy ... Pyruvate dehydrogenase function, regulation, and deficiency. The identification of modulatory genes involved in the function of ...
  http://giblinlab.org/tag/pyruvate-carboxylase-deficiency/
*  PC/pyruvate carboxylase cDNA ORF Clone in Cloning Vector, Human | SinoBiological
PC/pyruvate carboxylase cDNA ORF Clone, Human in pGEM-T Vector is confirmed by Full-length sequence verification, in stock ... PC/pyruvate carboxylase cDNA ORF Clone, Rat, untagged. RG81674-UT. PC/pyruvate carboxylase Lentiviral cDNA ORF Clone, Rat, C- ... PC/pyruvate carboxylase cDNA ORF Clone, Human, untagged. HG15615-UT. PC/pyruvate carboxylase cDNA ORF Clone, Human, C-GFPSpark ... PC/pyruvate carboxylase cDNA ORF Clone in Cloning Vector, Human. PC/pyruvate carboxylase cDNA ORF Clone in Cloning Vector, ...
  http://ru.sinobiological.com/PC-cDNA-Clone-g-16721.html
*  Manganese in the structure of Crystal Structure of S. Aureus Pyruvate Carboxylase A610T Mutant (pdb 3hb9)
The binding sites of Manganese atom in the structure of Crystal Structure of S. Aureus Pyruvate Carboxylase A610T Mutant (pdb ... Manganese in the structure of Crystal Structure of S. Aureus Pyruvate Carboxylase A610T Mutant (pdb 3hb9). ...
  http://manganese.atomistry.com/pdb3hb9.html
*  Manganese in the structure of Crystal Structure of Human Pyruvate Carboxylase (Missing The Biotin Carboxylase Domain At the N...
Missing The Biotin Carboxylase Domain At the N-Terminus) ... structure of Crystal Structure of Human Pyruvate Carboxylase ( ... The binding sites of Manganese atom in the structure of Crystal Structure of Human Pyruvate Carboxylase (Missing The Biotin ... Carboxylase Domain At the N-Terminus) (pdb code 3bg3). This binding sites where shown with 5.0 Angstroms radius around ...
  http://manganese.atomistry.com/pdb3bg3.html
*  Proteome Analysis of Skeletal Muscle From Obese and Morbidly Obese Women | Diabetes
... and pyruvate kinase, which increased with increased BMI, and carbonic anyhydrase 3 decreased with increasing BMI. ... we plan to investigate the role of AMPK in regulating downstream metabolic targets such as acetyl-CoA carboxylase and the ...
  http://diabetes.diabetesjournals.org/content/54/5/1283.full
*  Essential Bacillus subtilis genes | PNAS
... which converts these compounds to pyruvate, funneled into pyruvate dehydrogenase. The top part comprises four steps when ... whereas birA is required for the addition of a biotinyl group to carboxylase. The fatty acid chains are elongated by the ... 8, which is published as supporting information on the PNAS web site) from UDP-N-acetyl-glucosamine, phosphoenolpyruvate, d- ... The last two genes, pdhA and odh, encode subunits of pyruvate and 2-oxoglutarate dehydrogenase, respectively; growth of the ...
  http://www.pnas.org/content/100/8/4678
*  Publications
Pyruvate carboxylase deficiency--insights from liver transplantation. Nyhan WL, Khanna A, Barshop BA, Naviaux RK, Precht AF, ... Monitoring phosphorylation of the pyruvate dehydrogenase complex. Rardin MJ, Wiley SE, Naviaux RK, Murphy AN, Dixon JE. Anal ...
  http://naviauxlab.ucsd.edu/publications/
*  Genomic Organization of Plant Terpene Synthases and Molecular Evolutionary Implications | Genetics
... pyruvate/glyceraldehyde-3-phosphate pathway (Eisenreichet al. 1998; Lichtenthaler 1999), by which the monoterpenes (C10), ... such as the small subunit of ribulose-bisphosphate carboxylase/oxygenase and alcohol dehydrogenase (Clegget al. 1997). Very few ... The plastidial pool of IPP is derived from the glycolytic intermediates pyruvate and glyceraldehyde-3-phosphate and provides ...
  http://www.genetics.org/content/158/2/811
*  Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon...
Phosphoenolpyruvate carboxylase; PTS: Phosphoenolpyruvate:carbohydrate phosphotransferase system; PykAF: Pyruvate kinases A and ... and pyruvate (PYR)[2-4] (Figure1). In E. coli, PEP also participates as substrate in the reaction catalyzed by the pyruvate ... Phosphoenolpyruvate carboxylase; PTS: Phosphoenolpyruvate:carbohydrate phosphotransferase system; PykAF: Pyruvate kinases A and ... Phosphoenolpyruvate carboxylase; PTS: Phosphoenolpyruvate:carbohydrate phosphotransferase system; PykAF: Pyruvate kinases A and ...
  https://microbialcellfactories.biomedcentral.com/articles/10.1186/1475-2859-11-127
*  Reactive Oxygen Species Contribute to the Bactericidal Effects of the Fluoroquinolone Moxifloxacin in Streptococcus pneumoniae....
Since pyruvate is converted by pyruvate oxidase (SpxB) into hydrogen peroxide (H2O2), an increase in pyruvate would augment ... In addition, acetyl-CoA carboxylase was down-regulated, likely leading to an increase in acetyl-CoA. When coupled with an up- ... These included 3 glycolytic enzymes, which ultimately convert fructose-6P to pyruvate, and 2 enzymes that funnel P-sugars into ... Genes from several metabolic pathways involved in the production of pyruvate were up-regulated. ...
  http://www.vanopijnenlab.com/news/2015/11/9/reactive-oxygen-species-contribute-to-the-bactericidal-effects-of-the-fluoroquinolone-moxifloxacin-in-streptococcus-pneumoniae