Pyrroline-5-carboxylate reductase - Wikipedia
1-pyrroline-5-carboxylate reductase, NADPH-L-Delta1-pyrroline carboxylic acid reductase, and L-proline-NAD(P)+ 5-oxidoreductase ... In enzymology, a pyrroline-5-carboxylate reductase (EC 1.5.1.2) is an enzyme that catalyzes the chemical reaction L-proline + ... Yura T; Vogel HJ (1959). "Pyrroline-5-carboxylate reductase of Neurospora crassa: partial purification and some properties". ... Smith ME; Greenberg DM (1956). "Characterization of an enzyme reducing pyrroline-5-carboxylate to proline". Nature. 177 (4520 ...
![PYCR2 pyrroline-5-carboxylate reductase 2 [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
PYCR2 pyrroline-5-carboxylate reductase 2 [Homo sapiens (human)] - Gene - NCBI
pyrroline-5-carboxylate reductase 2. Names. P5C reductase 2. pyrroline-5-carboxylate reductase family member 2. NP_001258610.1 ... P5CR_dimer; Pyrroline-5-carboxylate reductase dimerisation. * NM_013328.4 → NP_037460.2 pyrroline-5-carboxylate reductase 2 ... PYCR2 pyrroline-5-carboxylate reductase 2 [Homo sapiens] PYCR2 pyrroline-5-carboxylate reductase 2 [Homo sapiens]. Gene ID: ... pyrroline-5-carboxylate reductase 2 (PYCR2). Title: Disease variants of human Δ(1)-pyrroline-5-carboxylate reductase 2 (PYCR2). ...
Functional Impact of a Cancer-Related Variant in Human Δ-Pyrroline-5-Carboxylate Reductase 1. | NECAT
Functional Impact of a Cancer-Related Variant in Human Δ-Pyrroline-5-Carboxylate Reductase 1.. Publication Type:. Journal ... p,Pyrroline-5-carboxylate reductase (PYCR) is a proline biosynthetic enzyme that catalyzes the NAD(P)H-dependent reduction of Δ ... Home » Functional Impact of a Cancer-Related Variant in Human Δ-Pyrroline-5-Carboxylate Reductase 1. ... pyrroline-5-carboxylate (P5C) to proline. Humans have three PYCR isoforms, with PYCR1 often upregulated in different types of ...
MedlinePlus: Genes: P
KEGG REACTION: R03293
SCOPe 2.08: Domain d2ahrd1: 2ahr D:153-256
PDB Compounds: (D:) putative pyrroline carboxylate reductase. SCOPe Domain Sequences for d2ahrd1:. Sequence; same for both ... Protein Pyrroline-5-carboxylate reductase ProC [116985] (2 species). *. Species Streptococcus pyogenes [TaxId:1314] [140776] (2 ... PDB Description: crystal structures of 1-pyrroline-5-carboxylate reductase from human pathogen streptococcus pyogenes ... d2ahrd1 a.100.1.10 (D:153-256) Pyrroline-5-carboxylate reductase ProC {Streptococcus pyogenes [TaxId: 1314]} ...
Human Metabolome Database: Showing metabocard for 1-Pyrroline-5-carboxylic acid (HMDB0001301)
5. Pyrroline-5-carboxylate reductase 3. General function:. Involved in oxidoreductase activity. Specific function:. Not ... 3. Pyrroline-5-carboxylate reductase 2. General function:. Involved in oxidoreductase activity. Specific function:. ... 2. Pyrroline-5-carboxylate reductase 1, mitochondrial. General function:. Involved in oxidoreductase activity. Specific ... In particular, it is synthesized via the oxidation of proline by pyrroline-5-carboxylate reductase 1 (PYCR1) (EC 1.5.1.2) or by ...
SCR 1q41-1q43 Genes
PYCR1: A Potential Prognostic Biomarker in Pancreatic Ductal Adenocarcinoma
Human pyrroline-5-carboxylate reductase (PYCR1) acts on Delta(1)-piperideine-6-carboxylate generating L-pipecolic acid. J ... Pyrroline-5-carboxylate reductase 1 promotes proliferation and inhibits apoptosis in non-small cell lung cancer. Oncol Lett. ... Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015; ... Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers. ...
Cell-free biocatalytic syntheses of l-pipecolic acid: a dual strategy approach and process intensification in flow - Green...
Chemistry Tree - Kurt L. Krause
2017) Resolving the Cofactor Binding Site in the Proline Biosynthetic Enzyme Human Pyrroline-5-Carboxylate Reductase 1. The ... 2017) Correcting the record - cofactor binding of human pyrroline-5-carboxylate reductase Acta Crystallographica Section a ...
BiGG Reaction P5CR in iAM Pf480
BiGG Reaction P5CR in iNRG857 1313
De novo assembly of red clover transcriptome based on RNA-Seq data provides insight into drought response, gene discovery and...
PROSITE
Delta 1-pyrroline-5-carboxylate reductase (P5CR) (EC 1.5.1.2) [1,2] is the enzyme that catalyzes the terminal step in the ... P5CR, PS00521; Delta 1-pyrroline-5-carboxylate reductase signature (PATTERN). * Consensus pattern:. [PALF]-x(2,3)-[LIV]-x(3)-[ ... A soybean gene encoding delta 1-pyrroline-5-carboxylate reductase was isolated by functional complementation in Escherichia ... biosynthesis of proline from glutamate, the NAD(P) dependent oxidation of 1-pyrroline-5-carboxylate into proline. ...
Search result - BRENDA Enzyme Database
DeCS
Pyrroline Carboxylate Reductases - Preferred Concept UI. M0018282. Scope note. A group of enzymes that catalyze the reduction ... Pyrroline Carboxylate Reductases Entry term(s). Carboxylate Reductases, Pyrroline Reductases, Pyrroline Carboxylate ... Pyrroline carboxylate reductases Entry term(s):. Carboxylate Reductases, Pyrroline. Reductases, Pyrroline Carboxylate. ... A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both ...
Carboxylic acids. Medical search
Pyrroline Carboxylate Reductases. A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the ... Thin LayerPyrroline Carboxylate ReductasesLycopersicon esculentumD-Amino-Acid OxidasePlant RootsEnoxacinPyrrolesCaproates ... Carbon RadioisotopesCyclohexanecarboxylic AcidsAlkenesLucanthoneCarboxylic Ester HydrolasesPyrroline Carboxylate ReductasesD- ... former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to ...
Redox Biology Center - Fingerprint - Research Nebraska
Network Portal - Gene DVU1451
HOMOLOGY MODELLING AND ANALYSIS OF PROTEIN DRUG TARGETS FOR ERYSIPELOTHRIX RHUSIOPATHIAE A BACTERIAL PATHOGEN CAUSING SWINE...
Patricia Alejandra Luz Crawford - Fingerprint
- Universidad de los Andes
L-proline biosynthesis in Pseudomonas simiae WCS417
Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae
... γ-glutamyl phosphate reductase), and Pro3p (Δ1-pyrroline-5-carboxylate (P5C) reductase) [6][7]. Proline is also synthesized ... 1-pyrroline-5-carboxylate reductase. J Bacteriol 174(11): 3782-3788. doi: 10.1128/jb.174.15.5176b.1992 ... Four permeases import proline and the toxic proline analogue azetidine-2-carboxylate into yeast. Yeast 21(3): 193-199. doi: ... maintains yeast replicative lifespan by regulating ribonucleotide reductase 1 (RNR1) gene transcription. Biochem Biophys Res ...
Bio2Vec
HAMAP rule MF 01925
GO:0004735; Molecular function: pyrroline-5-carboxylate reductase activity. GO:0006561; Biological process: proline ... RHEA:14109: L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH EC 1.5.1.2 ... RHEA:14105: L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH EC 1.5.1.2 ... Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.. ...
Differentially expressed genes in different stages treated with cAMP
GSE17721 0.5H VS 8H GARDIQUIMOD BMDC UP