Emil Kraepelin, more than any other individual, has shaped the nature of our psychiatric diagnostic system. Kraepelin published his final contribution to psychiatric nosology as an essay in 1920, which both modified and explicated the conceptual foundation for this approach to diagnosis. This essay was a response to a new generation of psychiatrists, particularly Karl Jaspers, Karl Birnbaum, and Ernst Kretschmer, who each challenged Kraepelins view that psychiatric disorders represent natural kinds, (i.e., truly distinct entities). They had argued for a structural analysis of psychosis stressing the impact of unique, personal attributes on the causes and clinical presentations of mental diseases. The authors give this text a close reading and conclude that it offers a final nuanced description of Kraepelins advanced nosologic views and his emerging interest in life history and culture. Kraepelin held fast to his position that psychiatric disorders represented distinct natural kinds, but acknowledged
Depression, stress and diet can all alter inflammation. This double-blind, randomized crossover study addressed the impact of daily stressors and a history of major depressive disorder (MDD) on inflammatory responses to high-fat meals. During two separate 9.5 h admissions, 58 healthy women (38 breast cancer survivors and 20 demographically similar controls), mean age 53.1 years, received either a high saturated fat meal or a high oleic sunflower oil meal. The Daily Inventory of Stressful Events assessed prior day stressors and the Structured Clinical Interview for DSM-IV evaluated MDD. As expected, for a woman with no prior day stressors, C-reactive protein (CRP), serum amyloid A (SAA), intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) were higher following the saturated fat meal than the high oleic sunflower oil meal after controlling for pre-meal measures, age, trunk fat and physical activity. But if a woman had prior day stressors, these meal-related
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McGill University - Department of Psychiatry. The Department of Psychiatry, McGill University/Douglas Research Centre are ... Save Assistant/Associate Professor (Research), Department of Psychiatry You need to sign in or create an account to save ... Assistant/Associate Professor (Research), Department of Psychiatry. *Montréal, Quebec (CA). *Salary will be commensurate with ...
Department of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan ...
Epigenetic aging in psychiatry: clinical implications and therapeutic opportunities *Camila N. C. Lima ...
Rapid and novel treatments in psychiatry: the future is now *Carolyn I. Rodriguez ...
Division of Psychiatry, University of Edinburgh, Edinburgh, EH10 5HF, UK. Andrew M. McIntosh ...
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Molecular Psychiatry (Mol Psychiatry) ISSN 1476-5578 (online) ISSN 1359-4184 (print) ...