Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions
The adhesion G-protein-coupled receptor CD97 is present in normal colonic enterocytes but overexpressed in colorectal carcinoma ... Proto-Oncogene Proteins c-akt / metabolism * Receptors, G-Protein-Coupled * Signal Transduction ... The adhesion G-protein-coupled receptor CD97 is present in normal colonic enterocytes but overexpressed in colorectal carcinoma ... This was associated with inactivation of glycogen synthase kinase-3beta (GSK-3beta) and activation of Akt. In summary, CD97 ...
Effect of black currant anthocyanins on the activation of endothelial nitric oxide synthase (eNOS) in vitro in human...
Akt) pathway. Black currant fruits have appreciable amounts of polyphenolic compounds including cyanidin-3-O-glucoside, ... Proto-Oncogene Proteins c-akt / metabolism * Ribes / chemistry* Substances * Anthocyanins * Plant Extracts ... Black currant juice samples (1 μL/mL) significantly increased the phosphorylation of Akt (p-Akt) and eNOS (p-eNOS) (P , 0.05). ... protein kinase B (Akt) pathway. Black currant fruits have appreciable amounts of polyphenolic compounds including cyanidin-3-O- ...
Page 1 | Search Results | Diabetes | American Diabetes Association
proto-oncogene proteins c-akt (1) * signal transduction (1) * skeletal myocytes (1) ... Open the PDF for Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through ... Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain ... View article titled, Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity ...
TRPC1 channels are critical for hypertrophic signaling in the heart.
Proto-Oncogene Proteins c-akt. *Phosphotransferases (Alcohol Group Acceptor). *Myocardium. *Mice, Knockout ... G protein-coupled receptor signaling is known to govern the hypertrophic response through the regulation of ion channel ... OBJECTIVE: Transient receptor potential canonical (TRPC) channels are G protein-coupled receptor operated channels previously ... mTOR and Akt is altered in Trpc1(-)(/)(-) mice. CONCLUSIONS: From these studies, we suggest that TRPC1 channels are critical ...
The Lou/C rat: a model of spontan... | Archive ouverte UNIGE
Mitochondrial Proteins/genetics/metabolism * Muscle, Skeletal/metabolism * Obesity/*metabolism * Proto-Oncogene Proteins c-akt/ ... as suggested by higher activation of the insulin receptor and of the Akt/protein kinase B pathway. Fat deposition was markedly ... In the inguinal adipose depot, expression of uncoupling protein-1 was detected in Lou/C but not in Wistar rats, in keeping with ...
Proto-oncogene tyrosine-protein kinase Src - Wikipedia
Src (gene) has been shown to interact with the following signaling pathways: PI3K Akt IKK NFkB Caspase 9 STAT3 p38 MAPK VEGF IL ... Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc ... Proto-oncogene tyrosine-protein kinase Src) at the PDBe-KB. Portal: Biology (Articles with short description, Short description ... This proto-oncogene may play a role in the regulation of embryonic development and cell growth. When src is activated, it ...
List of MeSH codes (D12.776) - Wikipedia
... proto-oncogene proteins c-abl MeSH D12.776.624.664.700.168 - proto-oncogene proteins c-akt MeSH D12.776.624.664.700.169 - proto ... proto-oncogene proteins c-bcr MeSH D12.776.624.664.700.172 - proto-oncogene proteins c-cbl MeSH D12.776.624.664.700.174 - proto ... proto-oncogene proteins c-fes MeSH D12.776.624.664.700.179 - proto-oncogene proteins c-fos MeSH D12.776.624.664.700.180 - proto ... proto-oncogene proteins c-hck MeSH D12.776.624.664.700.182 - proto-oncogene proteins c-jun MeSH D12.776.624.664.700.183 - proto ...
NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression | Research Square
NFAT2: Nuclear factor of activated T cells 2; FasL: Fas ligand; COX-2: cyclooxygenase-2; c-myc: myc proto-oncogene protein; HCC ... Besides NFAT2, the expression of FasL was also modulated by the activated AKT and ERK. The activated AKT effectively inhibited ... myc proto-oncogene protein (c-myc), cyclooxygenase-2 (COX-2), Fas ligand (FasL) and also generates crosstalks with ERK/MAPK ... AKT (1:1000), p-AKT (1:1000), ERK (1:1000), p-ERK (1:1000), COX-2 (1:1000), c-myc (1:2000), and β-Actin (1:1000). After primary ...
14-3-3 Binding to Pim-phosphorylated Ser166 and Ser186 of human Mdm2-Potential interplay with the PKB/Akt pathway and p14(ARF)<...
Tumor Suppressor Protein p14ARF Medicine & Life Sciences 81% * Proto-Oncogene Proteins c-akt Medicine & Life Sciences 64% ... but not protein kinase B (PKB)/Akt-phosphorylated Ser166 and Ser188. Pim-mediated phosphorylation of Ser186 blocks ... but not protein kinase B (PKB)/Akt-phosphorylated Ser166 and Ser188. Pim-mediated phosphorylation of Ser186 blocks ... but not protein kinase B (PKB)/Akt-phosphorylated Ser166 and Ser188. Pim-mediated phosphorylation of Ser186 blocks ...
AKT antibody (CL488-60203) | Proteintech
AKT antibody for IF and reacts with human, mouse, rat. ... Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK ... The immunogen of CL488-60203 is AKT Fusion Protein expressed in E. coli. ... "AKT antibodies" comparison. At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As ... The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. ...
Bell, Graeme | Profiles RNS
beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation.
Proto-Oncogene Proteins c-akt. Citation. APA Chicago ICMJE MLA NLM Ahn, S., Kim, J., Hara, M. R., Ren, X.-R., & Lefkowitz, R. J ... Receptor stimulation leads to concerted activation of two pathways, ERK/p90RSK and PI3K/AKT, which converge to phosphorylate ... beta-Arrestins, originally discovered as terminators of G protein-coupled receptor signaling, have more recently been ... which has been previously shown to activate beta-arrestin but not G protein-dependent signaling, and are abrogated by beta- ...
Jeffrey E. Pessin - Publications - Albert Einstein College of Medicine
Insulin Receptor Substrate Proteins 85% * Proto-Oncogene Proteins c-akt 78% * Insulin Receptor 74% ... Insulin-mediated PI3K and AKT signaling. Kwon, H. J. & Pessin, J. E., Jan 24 2020, The Liver: Biology and Pathobiology. wiley, ... ATG16L1 autophagy pathway regulates BAX protein levels and programmed cell death. Chen, F., Amgalan, D., Kitsis, R. N., Pessin ... Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α. Song, Z., Xiaoli, ...
Department of Exercise Science - Research output - Experts@Syracuse
Proto-Oncogene Proteins c-akt 100% * Muscular Atrophy 96% * Diaphragm 85% * Artificial Respiration 80% ... Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women. Vingren, J. L., ... Plantaris muscle of aged rats demonstrates iron accumulation and altered expression of iron regulation proteins. Jung, S. H., ... Effect of circulating growth hormone on muscle IGF-I protein concentration in female mice with growth hormone receptor gene ...
Department of Exercise Science - Research output - Experts@Syracuse
Proto-Oncogene Proteins c-akt 100% * Muscular Atrophy 96% * Diaphragm 85% * Artificial Respiration 80% ... Effect of resistance exercise on muscle steroid receptor protein content in strength-trained men and women. Vingren, J. L., ... Plantaris muscle of aged rats demonstrates iron accumulation and altered expression of iron regulation proteins. Jung, S. H., ... PKB-Akt) signalling. McClung, J. M., Kavazis, A. N., Whidden, M. A., Deruisseau, K. C., Falk, D. J., Criswell, D. S. & Powers, ...
Abundant Active Ingredients of Green Tea Regulate Glucose Metabolism in 3T3-L1 Cell Line - Fingerprint
- Aston Research...
Synergistic neuroprotection by epicatechin and quercetin: Activation of convergent mitochondrial signaling pathways -...
Frontiers | Umbelliferone and scopoletin target tyrosine kinases on fibroblast-like synoviocytes to block NF-κB signaling to...
... proto-oncogene tyrosine-protein kinase Src (Src), Akt serine/threonine kinase 1 (Akt1), receptor tyrosine-protein kinase ErbB-2 ... From various databases, 5104 RA-related proteins, 116 umbelliferone protein targets, and 110 scopoletin protein targets were ... corresponding protein targets, and related pathways; protein-protein interaction (PPI) networks were generated using STRING ( ... Thirdly, the two compounds are identified with crucial target proteins (including TKs) and pathways (including RTK/PI3K/Akt/NF- ...
Gab3 overexpression in human glioma mediates Akt activation and tumor cell proliferation. - NextBio article
Adaptor Proteins, Signal Transducing Gab3 protein, human RNA, Messenger Proto-Oncogene Proteins c-akt ... Akt activation in cancer tissues was also suppressed by Gab3 shRNA. Together, we conclude that Gab3 overexpression in human ... Gab3 mRNA and protein expression was significantly elevated in human glioma tissues and glioma cells. Its level was however low ... Adaptor Proteins, Signal Transducing Animals Brain Neoplasms Cell Proliferation Enzyme Activation Gene Knockdown Techniques ...
Yang, Yiping | Duke Cancer Institute
Proto-Oncogene Proteins c-akt. RNA, Messenger. Receptors, Cell Surface. Receptors, Interleukin-1 ... Humoral immune responses to the input viral proteins generate neutralizing antibodies that thwart attempts to effectively ...
The case of an APDS patient: Defects in maturation and function and decreased in vitro anti-mycobacterial activity in the...
Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; TOR Serine-Threonine Kinases; Young Adult ... Our data show that the constitutive activation of Akt-mTOR pathway induces important alterations also in the myeloid ... Our data show that the constitutive activation of Akt-mTOR pathway induces important alterations also in the myeloid ...
Cell survival. Medical search. Definitions
Proto-Oncogene Proteins c-aktProto-Oncogene ProteinsPhosphatidylinositol 3-KinasesProtein-Serine-Threonine Kinases ... Proto-Oncogene Proteins c-aktRetrospective StudiesPhosphorylationProto-Oncogene ProteinsPhosphatidylinositol 3-KinasesProtein- ... v-akt protein is the viral homologue of PROTO-ONCOGENE PROTEINS C-AKT.. ... Proto-Oncogene Proteins c-akt. A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH ...
Chlamydial entry involves TARP binding of guanine nucleotide exchange factors<...
keywords = "HeLa cells, intracellular signaling peptides and proteins, humans, tyrosine, proto-oncogene proteins c-akt, ... nuclear proteins, phosphorylation, transfection, actins, bacterial adhesion, cytoskeletal proteins, signal transduction", ... Chlamydia trachomatis attachment to cells induces the secretion of the elementary body-associated protein TARP (Translocated ... abstract = "Chlamydia trachomatis attachment to cells induces the secretion of the elementary body-associated protein TARP ( ...
Related GMR Articles | Page 5 | GMR | Genetics and Molecular Research | The Original by FUNPEC-RP
Proto-Oncogene Proteins c-akt AKT1, also known as v-akt murine thymoma viral oncogene homolog 1, is involved in the regulation ... Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction; Young Adult ... Adaptor Proteins, Signal Transducing; Adult; Aged; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell ... Adult; Alleles; Brazil; Carrier Proteins; Case-control studies; Cation Transport Proteins; Diabetes, Gestational; Female; Gene ...
IGF-1 Protects Intestinal Epithelial Cells From Oxidative Stress-Induced Apoptosis - McMaster Experts
Proto-Oncogene Proteins c-akt (MeSH) * Rats (MeSH) * Reactive Oxygen Species (MeSH) ... Western blotting was performed to assess phosphorylation of Akt, a downstream effector of PI3-K. Cell Death Detection ELISA, ... H2O2-induced phosphorylation of Akt was further increased with IGF-1 treatment; wortmannin abolished these effects in RIE-1 ...
Iris Neoplasms
Somatic PIK3CA Mutations in Sporadic Cerebral Cavernous Malformations.
Proto-Oncogene Proteins c-akt. dc.subject. Class I Phosphatidylinositol 3-Kinases. ...
Degerman, E.<...