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*  A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration | Journal of Neuroscience
2000) Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell 103:583-594. ... Axonal transport is significantly inhibited in a mouse model of familial ALS. To examine the contribution of axonal transport ... A, Schematic for dynein pull-down assays followed by protein microarray analysis. B, Dynein pull-downs isolate proteins ... However, ∼9% (52 proteins) showed an increased association, and ∼17% (102 proteins) showed a decreased association with dynein ...
  http://www.jneurosci.org/content/29/31/9903.full?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=1&andorexacttitle=and&andorexacttitleabs=and&fulltext=kinexus&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
*  Vapb - Vesicle-associated membrane protein-associated protein B - Mus musculus (Mouse) - Vapb gene & protein
Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular ... endoplasmic reticulum unfolded protein response Source: MGI. *ER to Golgi vesicle-mediated transport Source: MGI ... Protein-protein interaction databases. Protein interaction database and analysis system. More...IntActi. Q9QY76. 2 interactors. ... Protein-protein interaction databases. Protein interaction database and analysis system. More...IntActi. Q9QY76. 2 interactors. ...
  http://www.uniprot.org/uniprot/Q9QY76
*  The cell. 5. Vesicular traffic. Form reticulum to Golgi. Atlas of plant and animal histology.
Proteins Carbohydrates Permeability, fluidity Asymmetry, repairing Synthesis Transport Adhesion. Cell junctions. 4. Nucleus. ... Endoplasmic reticulum resident transmembrane proteins will be directly selected by COPI proteins, but soluble resident proteins ... any protein to be transported must be properly folded. Otherwise, it will be removed. A quality control of proteins is always ... Thus, COPII, through adaptor proteins, can select and concentrate cargoes in the nascent vesicles, which will be transported to ...
  http://mmegias.webs.uvigo.es/02-english/5-celulas/5-reticulo-golgi.php
*  "Analysis of the Ovine NEU1 Gene in a Unique Model of GM1 Gangliosidosi" by Alex Quackenbush
The α-neuraminidase protein is coded for by the NEU1 gene and is, a glycohydrolitic enzyme that is active in the lysosome. The ... LMC members include β-gal, α-neuraminidase and the Protective Protein Cathepsin A (PPCA). In a unique ovine model of GM1, there ... The enzyme, β-gal, is a member of the Lysosomal Multienzyme Complex (LMC), which transports proteins to the lysosome and ... The enzyme, β-gal, is a member of the Lysosomal Multienzyme Complex (LMC), which transports proteins to the lysosome and ...
  https://pilotscholars.up.edu/hon_projects/13/
*  Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human...
... disrupting both Golgi organization and protein transport. RN-tre is the GAP for Rab43, and controls retrograde transport into ... We used the 38 human Rab GTPase activating proteins (GAPs) to identify which of the 60 Rabs encoded in the human genome ... disrupting both Golgi organization and protein transport. RN-tre is the GAP for Rab43, and controls retrograde transport into ... Recombinant Fusion Proteins, Two-Hybrid System Techniques, rab GTP-Binding Proteins, rab1 GTP-Binding Proteins ...
  https://www.neuroscience.ox.ac.uk/publications/528821
*  The TRAPPIII complex activates the GTPase Ypt1 (Rab1) in the secretory pathway | JCB
The transport protein particle (TRAPP) complexes activate Rab GTPases by catalyzing GDP/GTP nucleotide exchange. In mammalian ...
  http://jcb.rupress.org/content/217/1/283
*  Copb2 - Coatomer subunit beta' - Rattus norvegicus (Rat) - Copb2 gene & protein
... and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be ... which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex ... recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also ... The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- ...
  http://www.uniprot.org/uniprot/O35142
*  Remodeling of organelle-bound actin is required for yeast vacuole fusion | JCB
Actin filaments are required for the transport and spatial targeting of secretory proteins (Pruyne et al., 1998; Guo et al., ... The docking stage of yeast vacuole fusion requires the transfer of proteins from a cis-SNARE complex to a Rab/Ypt protein. J. ... antibody to the actin regulatory proteins Las17p (yeast Wiskott-Aldrich syndrome protein) or Arp2/3, or deletion of actin ... Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. Mol. Cell. 6:661-671. ...
  http://jcb.rupress.org/content/158/4/669
*  COPE Full-Length MS Protein Standard - Creative Proteomics
... and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least ... The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds ... COPE Full-Length MS Protein Standard (NP_009194), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was ... Customized Synthesized Peptide/Proteins. Stable Isotope Labeled Full Length MS Protein Standard. Stable Isotope Labeled MS ...
  https://www.creative-proteomics.com/product/detail-cpfl303531_1708.htm
*  New Saccharomyces Sequences 04/11/96
BOS1; Vesicular transport protein (Swiss Prot.; accession number P25385); ; SIC1; Substrate and inhibitor of the cyclin- ... Membrane protein involved in endocytosis (PIR; accession number S45053); ; L9449.15; XDJ1; DnaJ protein homolog (Swiss Prot. ... accession number P32485). Note that the; protein predicted to be encoded by this gene is 27 amino; acids longer at the C- ... accession number P08622),; and to other DnaJ-like proteins (e.g., MAS5_YEAST, Swiss; Prot. accession number P25491); ; L9449.2 ...
  http://www.bio.net/bionet/mm/yeast/1996-April/005052.html
*  YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta. -...
... and potentially links YSK1 signaling at the Golgi apparatus with protein transport events, cell adhesion, and polarity ... We show that the mammalian Ste20 kinases YSK1 and MST4 target to the Golgi apparatus via the Golgi matrix protein GM130. In ... Here, we identify a scaffolding function for the Golgi matrix protein GM130 that sheds light on how such signaling events may ... and potentially links YSK1 signaling at the Golgi apparatus with protein transport events, cell adhesion, and polarity ...
  https://www.neuroscience.ox.ac.uk/publications/528836/
*  Center for Nonlinear Dynamics » Publication » Endogenous GSK-3/Shaggy regulates bidirectional axonal transport of the Amyloid...
Neurons rely on microtubule (MT) motor proteins such as kinesin-1 and dynein to transport essential cargos between the cell ... Endogenous GSK-3/Shaggy regulates bidirectional axonal transport of the Amyloid Precursor Protein. ... has been proposed to be a central player in AD and to regulate axonal transport by the MT motor protein kinesin-1. Using ... By measuring the forces motors generate in vivo, we ?nd that GSK-3 regulates transport by altering the activity of kinesin-1 ...
  https://chaos.utexas.edu/publications/endogenous-gsk-3shaggy-regulates-bidirectional-axonal-transport-of-the-amyloid-precursor-protein
*  The cell. 5. Vesicular traffic. Vacuoles. Atlas of plant and animal histology.
Proteins Carbohydrates Permeability, fluidity Asymmetry, repairing Synthesis Transport Adhesion. Cell junctions. 4. Nucleus. ... Structural proteins. Carbohydrates. Glycoproteins. Types. 3. Cell membrane. Lipids. ... In some cells, they are the place to store carbohydrates and proteins. This clearly happens in seeds where vacuoles accumulate ... Delivering of proteins to the plant vacuole--an update. International journal of molecular sciences 15: 7611-762. ...
  http://mmegias.webs.uvigo.es/02-english/5-celulas/5-vacuolas.php
*  Rhesus Proteins Transport Ions, not Gas
Further reports about: , Biochemistry , Centre , Gas , NH4+ , PNAS , Phone , Rhesus , Transport , blood , protein , proteins , ... Biochemistry »Centre »Gas »NH4+ »PNAS »Phone »Rhesus »Transport »blood »protein »proteins »protons ... Rhesus Proteins Transport Ions, not Gas. 27.06.2014. Using artificial lipid vesicles, biochemists show how membrane proteins ... Direct observation of electrogenic NH4+ transport in ammonium transport (Amt) proteins, PNAS 2014; published ahead of print ...
  http://www.innovations-report.com/html/reports/life-sciences/rhesus-proteins-transport-ions-not-gas.html
*  SDS-assisted protein transport through solid-state nanopores - Nanoscale (RSC Publishing)
... including unfolding of the complex tertiary structure of the proteins and enforcing their unidirectional translocation through ... Using nanopores for single-molecule sequencing of proteins - similar to nanopore-based sequencing of DNA - faces multiple ... SDS-assisted protein transport through solid-state nanopores L. Restrepo-Pérez, S. John, A. Aksimentiev, C. Joo and C. Dekker, ... Our simulations and experiments prove that SDS-treated proteins show a considerable loss of the protein structure during the ...
  http://pubs.rsc.org/en/content/articlelanding/2017/nr/c7nr02450a
*  Intracellular protein transport | Springer for Research & Development
In the last chapter we have seen how proteins are inserted post-translationally into mitochondria. Similar pathways exist for ... Buxbaum E. (2007) Intracellular protein transport. In: Fundamentals of Protein Structure and Function. Springer, Boston, MA. * ... after the protein has reached its destination, the exception are nuclear proteins because the nucleus breaks down during each ... Hence after each cell division nuclear proteins need to be reimported.. Keywords. Early Endosome Late Endosome Signal ...
  https://rd.springer.com/chapter/10.1007/978-0-387-68480-2_16
*  Sec31a - Protein transport protein Sec31A - Rattus norvegicus (Rat) - Sec31a gene & protein
... which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the ... Component of the coat protein complex II (COPII) ... ER-Golgi transport, Protein transport, Transport. Enzyme and ... Protein transport protein Sec31AAdd BLAST. 1249. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... Cluster: Protein transport protein Sec31A. 5. Q9Z2Q1-2. O94979-6. UPI000789628B. UPI000787437B. UPI0007876876. UPI00072F7B5D. ...
  http://www.uniprot.org/uniprot/Q9Z2Q1
*  Mitochondrial protein-transporting ATPase - Wikipedia
In enzymology, a mitochondrial protein-transporting ATPase (EC 3.6.3.51) is an enzyme that catalyzes the chemical reaction ATP ... Without the presence of ATPase, carboxy-terminal segment is not able to bind to protein of Tim44. As mtHsp70 transmits the ... Krimmer, T.; Rassow, J.; Kunau, W. H.; Voos, W.; Pfanner, N. (2000-08-01). "Mitochondrial protein import motor: the ATPase ... Voos W, Martin H, Krimmer T, Pfanner N (November 1999). "Mechanisms of protein translocation into mitochondria". Biochimica et ...
  https://en.wikipedia.org/wiki/Mitochondrial_protein-transporting_ATPase
*  Chloroplast protein-transporting ATPase - Wikipedia
"Protein-specific energy requirements for protein transport across or into thylakoid membranes. Two lumenal proteins are ... "Identification of the SecA protein homolog in pea chloroplasts and its possible involvement in thylakoidal protein transport". ... In enzymology, a chloroplast protein-transporting ATPase (EC 3.6.3.52) is an enzyme that catalyzes the chemical reaction ATP + ... The systematic name of this enzyme class is ATP phosphohydrolase (chloroplast protein-importing). Cline K, Ettinger WF, Theg SM ...
  https://en.wikipedia.org/wiki/Chloroplast_protein-transporting_ATPase
*  Structure of the TatC core of the twin-arginine protein transport system.
... pathway is one of two general protein transport systems found in the prokaryotic cytoplasmic membrane and is conserved in the ... Membrane Transport Proteins / chemistry*, metabolism. Models, Molecular*. Protein Binding. Protein Sorting Signals. Protein ... The defining, and highly unusual, property of the Tat pathway is that it transports folded proteins, a task that must be ... The twin-arginine translocation (Tat) pathway is one of two general protein transport systems found in the prokaryotic ...
  http://www.biomedsearch.com/nih/Structure-TatC-core-twin-arginine/23201679.html
*  FadL outer membrane protein transport family - Wikipedia
Outer membrane transport proteins (OMPP1/FadL/TodX) family includes several proteins that are involved in toluene catabolism ... This family also includes protein FadL involved in translocation of long-chain fatty acids across the outer membrane. It is ... "Identification of a membrane protein and a truncated LysR-type regulator associated with the toluene degradation pathway in ...
  https://en.wikipedia.org/wiki/FadL_outer_membrane_protein_transport_family
*  Discovery of a Novel Protein Transport System
Discovery of an Archetypal Protein Transport System in Bacterial Outer Membranes. Dr Joel Selkrig (Lithgow Lab) and colleagues ... We discovered a novel protein transport system, the TAM, found in most sequenced gram-negative bacteria that's required for ... Discovery of an archetypal protein transport system in bacterial outer membranes. Nat Struct Mol Biol. 2012. Abstract. Bacteria ... Perhaps erroneously, proteins called 'autotransporters' have long been thought to be one of these protein secretion systems. ...
  http://www.med.monash.edu.au/biochem/selkrig-tam.html
*  protein transport - Semantic Scholar
... to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport. ... The process of moving proteins from one cellular compartment (including extracellular) ... protein transport. Known as: Protein Transports, Protein Trafficking, Trafficking, Protein (More). The process of moving ... Protein-specific energy requirements for protein transport across or into thylakoid membranes. Two lumenal proteins are ...
  https://www.semanticscholar.org/topic/protein-transport/88571
*  Sec61a1 - Protein transport protein Sec61 subunit alpha isoform 1 - Rattus norvegicus (Rat) - Sec61a1 gene & protein
Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or ... through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity). ... Protein transport protein Sec61 subunit alpha isoform 1Add BLAST. 476. Proteomic databases. PaxDb, a database of protein ... Protein transport, Translocation, Transport. Enzyme and pathway databases. Reactome - a knowledgebase of biological pathways ...
  http://www.uniprot.org/uniprot/P61621
*  SEC61A1 - Protein transport protein Sec61 subunit alpha isoform 1 - Homo sapiens (Human) - SEC61A1 gene & protein
Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or ... through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity). ... Cluster: Protein transport protein Sec61 subunit alpha isoform 1. 20. P61619-3. T0NQQ4. F6VV24. C9JXC6. B3KNG2. G7N7W2. G7PIZ7 ... Cluster: Protein transport protein Sec61 subunit alpha isoform 1. 271. P61619-3. T0NQQ4. F6VV24. C9JXC6. B3KNG2. G7N7W2. G7PIZ7 ...
  http://www.uniprot.org/uniprot/P61619