Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis |...
Protein Lysates, Immunoprecipitation, and Western Blot. Protein lysate, cytosol and nuclear protein extraction, ... protein disulfide isomerase family A, member 6, ER protein 44, and disulfide bond oxidoreductase A-like protein. Thus, we ... A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization. Proc Natl Acad Sci USA 2008;105: ... Adipocyte Spliced Form of X-Box-Binding Protein 1 Promotes Adiponectin Multimerization and Systemic Glucose Homeostasis. ...http://diabetes.diabetesjournals.org/content/63/3/867.full
A scissor blade-like closing mechanism implicated in transmembrane signaling in a Bacteroides hybrid two-component system.
Protein Binding. Protein Kinases / chemistry, genetics, metabolism. Protein Multimerization. Protein Structure, Tertiary. ... 0/Bacterial Proteins; 9005-49-6/Heparin; 9050-30-0/Heparitin Sulfate; EC 2.7.-/Protein Kinases ... Bacterial Proteins / chemistry, genetics, metabolism*. Bacteroides / genetics, metabolism*. Binding Sites / genetics. Cell ... 22539977 - Role of dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epitheli.... 22387217 - Indirubin ...http://www.biomedsearch.com/nih/scissor-blade-like-closing-mechanism/22532667.html
Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Protein Multimerization. Protein Structure, Quaternary. Protein Structure, Tertiary. Protein Subunits. Recombinant Fusion ... 0/Intracellular Signaling Peptides and Proteins; 0/NEDD8 protein, human; 0/Protein Subunits; 0/Recombinant Fusion Proteins; 0/ ... Intracellular Signaling Peptides and Proteins / chemistry*, genetics, metabolism*. Models, Molecular. Molecular Dynamics ... Ubiquitins; 74-79-3/Arginine; 7440-66-6/Zinc; EC 3.4.-/Peptide Hydrolases; EC 3.4.-.-/COPS5 protein, human ...http://www.biomedsearch.com/nih/Insights-into-regulation-human-COP9/23288897.html
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for...
Nerve Tissue Proteins / genetics, metabolism*. Nuclear Proteins / genetics, metabolism*. Protein Multimerization*. RNA, ... 0/Electron Transport Chain Complex Proteins; 0/HTT protein, human; 0/Nerve Tissue Proteins; 0/Nuclear Proteins; 0/RNA, ... Previous Document: The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of hu.... ... The mutant Htt oligomers and the mitochondrial structural proteins were quantified in the striatum and frontal cortex of HD ...http://www.biomedsearch.com/nih/Abnormal-mitochondrial-dynamics-loss-mutant/21257639.html
Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization.
... are cell-permeable small molecules capable of dimerizing two protein targets. The most widely used CID, the natural product ... Protein Binding. Protein Multimerization. Saccharomyces cerevisiae / chemistry*, genetics, metabolism*. Grant Support. ID/ ... to the FK506/rapamycin binding protein FKBP(3) and a domain of the mTOR protein termed FRB.(4) A variety of biological ... heterodimerizes the DNA-binding LexA domain-DHFR fusion protein and a B42-FKBP transcriptional activator fusion protein, ...http://www.biomedsearch.com/nih/Conditional-glycosylation-in-eukaryotic-cells/18788807.html
Structural insights into the recognition properties of human ficolins.
Ficolins are oligomeric proteins assembled from collagen-like stalks and fibrinogen- ... Protein Multimerization. Protein Structure, Quaternary. Protein Structure, Tertiary. Receptors, Pattern Recognition / ... Complement System Proteins / immunology. Humans. Immunity, Innate. Lectins / chemistry, immunology*. N-Acetylneuraminic Acid / ... Ficolins are oligomeric proteins assembled from collagen-like stalks and fibrinogen-like domains that have the ability to sense ...http://www.biomedsearch.com/nih/Structural-insights-into-recognition-properties/20375619.html
Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights |...
Complications arise if protein multimerization occurs. The complement fragment C3d is a 35 kDa cleavage fragment of C3b that ... 7. Modelling of protein-protein complexes. The utility of constrained modelling is enhanced by its extension to protein-protein ... 2007 Small-angle X-ray scattering from RNA, proteins, and protein complexes. Annu. Rev. Biophys. Biomol. Struct. 36, 307-327. ( ... It is applicable to protein sizes above approximately 15 kDa. The first overall views of many protein structures have been ...http://rsif.royalsocietypublishing.org/content/6/Suppl_5/S679
Effects of XylS expression variations on induced and un | Open-i
Bacterial Proteins/biosynthesis*. *Gene Expression Regulation, Bacterial*. *Metabolic Networks and Pathways/genetics* ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4225500_1471-2180-13-262-4&req=4
A region of the ion mobility-mass spectrometry data o | Open-i
Bottom Line: Self-association does not affect the proteins' ability to interact with RNA as demonstrated by ion mobility-mass ... Bottom Line: Self-association does not affect the proteins' ability to interact with RNA as demonstrated by ion mobility-mass ... The results also clearly indicate that only 1:1 protein-RNA complexes are present in both the monomeric and dimeric forms (ML, ... The results also clearly indicate that only 1:1 protein-RNA complexes are present in both the monomeric and dimeric forms (ML, ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4150798_gku700fig6&req=4
Determination of threshold concentration for CtpS polym | Open-i
Escherichia coli Proteins/chemistry/genetics/metabolism*. *Recombinant Fusion Proteins/chemistry/genetics/metabolism* ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4126345_elife03638fs001&req=4
Effect of 14-3-3γ on TH phosphorylation and dephosphor | Open-i
14-3-3 Proteins/metabolism*. *Serine/metabolism*. *Tyrosine 3-Monooxygenase/chemistry/metabolism* ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4125734_zjw0081448330005&req=4
Z α1-antitrypsin expression enhances NF-κB signalling | Open-i
... monocyte chemoattractant protein-1 (MCP-1) and interferon gamma-induced protein-10 (IP-10) was performed (Fig. 1B). This ... monocyte chemoattractant protein-1 (MCP-1) and interferon gamma-induced protein-10 (IP-10) was performed (Fig. 1B). This ... Moreover, we show that rather than being a response to protein polymers, NF-κB signalling in airway-derived cells represents a ... Moreover, we show that rather than being a response to protein polymers, NF-κB signalling in airway-derived cells represents a ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4007119_ddt48701&req=4
Relationships between the empirical parameters and .Th | Open-i
Prion proteins are known to misfold into a range of different aggregated forms, showing different phenotypic and pathological ... Prion proteins are known to misfold into a range of different aggregated forms, showing different phenotypic and pathological ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2697384_pcbi.1000420.g001&req=4
Dimerization of ANTAR-containing proteins.A) Comparison | Open-i
Dimerization of ANTAR-containing proteins.A) Comparison of size exclusion chromatography profiles (Superdex-75 column) for ... ANTAR proteins are widespread bacterial regulatory proteins that have RNA-binding output domains and utilize antitermination to ... ANTAR proteins are widespread bacterial regulatory proteins that have RNA-binding output domains and utilize antitermination to ... An ANTAR protein, EutV, regulates the ethanolamine-utilization genes (eut) in Enterococcus faecalis. Using this system, we ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3369931_pgen.1002666.g005&req=4
Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFα | JCB
Lumenal protein multimerization in the distal secretory pathway/secretory granules. Curr. Opin. Cell Biol. 14:448-453. ... The supernatant was assayed for protein content (Bio-Rad Laboratories protein assay), and 20-50 μg of total protein from each ... GAIP, a Galphai-3-binding protein, is associated with Golgi-derived vesicles and protein trafficking. Am. J. Physiol. 276:C497- ... utilizing specific soluble NSF attachment protein receptor (SNARE) proteins to fuse with the recycling endosome. Within ...http://jcb.rupress.org/content/178/1/57.long
Cell viability in the presence of PMA, ConA, MCSF and R | Open-i
... core protein as a reduction sensitive heteromer. Several biochemical properties of the enzyme were changed when it was bound to ... core protein as a reduction sensitive heteromer. Several biochemical properties of the enzyme were changed when it was bound to ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3105995_pone.0020616.g001&req=4
Comer F[au] - PubMed - NCBI
... reciprocity with O-phosphorylation and putative roles in protein multimerization.. Hart GW, Kreppel LK, Comer FI, Arnold CS, ... Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N- ... Localization of the O-GlcNAc transferase and O-GlcNAc-modified proteins in rat cerebellar cortex. ... O-Glycosylation of nuclear and cytosolic proteins. Dynamic interplay between O-GlcNAc and O-phosphate. ...https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Comer+F%5Bau%5D&dispmax=50
"Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs i" by John J. Kaminski III, Stefan A. Schattgen et al.
Nuclear Proteins; *Nucleotide Motifs; Oligodeoxyribonucleotides; Protein Binding; Protein Multimerization; Signal Transduction ... Animals; Anti-Inflammatory Agents; Cell Line; Cluster Analysis; Cytoskeletal Proteins; Cytosol; DNA; DNA-Binding Proteins; Gene ...https://escholarship.umassmed.edu/faculty_pubs/519/
Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly | Journal of...
Characterization of hepatitis C virus core protein multimerization and membrane envelopment: revelation of a cascade of core- ... 8). These results therefore suggest that the D263A mutation does not drastically affect core protein multimerization. ... HCV core protein quantification.HCV core protein was quantified by a fully automated chemiluminescent microparticle immunoassay ... Oligomerization of hepatitis C virus core protein is crucial for interaction with the cytoplasmic domain of E1 envelope protein ...https://jvi.asm.org/content/91/8/e00048-17
SEC-MALS results of HPC2 Cterm and SUPC2 Ccore in Ca2+- | Open-i
... three different amounts of HPC2 Cterm protein were analyzed by Sup ... Protein Isoforms/chemistry/genetics/metabolism. *Protein Multimerization. *Protein Structure, Secondary. *Protein Structure, ... 2, C and D). Because the monomer of the SUPC2 Ccore protein is predicted to have a mass of 21.3 kDa, the averaged molar mass ... 2, C and D). Because the monomer of the SUPC2 Ccore protein is predicted to have a mass of 21.3 kDa, the averaged molar mass ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4400361_zbc0191514180002&req=4
Stress Granules and ALS: A Case of Causation or Correlation? | Springer for Research & Development
... is a fatal neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. These aggregates are ... Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules. Nucleic Acids ... Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate ... Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins ...https://rd.springer.com/chapter/10.1007%2F978-3-319-89689-2_7
D5 - Factbites
Biochemical and Genetic Analysis of the Vaccinia Virus D5 Protein: Multimerization-Dependent ATPase Activity Is Required To ... Biochemical and Genetic Analysis of the Vaccinia Virus D5 Protein: Multimerization-Dependent ATPase Activity Is Required To ... Biochemical and Genetic Analysis of the Vaccinia Virus D5 Protein: Multimerization-Dependent ATPase Activity Is .... ... Sidhu A (1998) Coupling of D1 and D5 dopamine receptors to multiple G proteins: implications for understanding the diversity in ...http://www.factbites.com/topics/D5
Department of Entomology: Faculty
2003) The C-Terminus of the Hermes Transposase Contains a Protein Multimerization Domain. Insect Biochem. and Molec. Biol. 33: ... Green fluorescent protein as a genetic marker in transgenic Aedes aegypti. Insect Molec. Biol .9: 1-10. Saville, K. J., W. D. ... Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc. Natl. Acad. Sci. USA, ... Nuclear Location of the Hermes Transposase Depends on Basic Amino Acid Residues at the N-Terminus of the Protein. Journal of ...http://www.entomology.ucr.edu/faculty/atkinson.html
Immunohistochemical staining of the VEGFR-1 ligands and | Open-i
Protein Multimerization. *Signal Transduction. *Vascular Endothelial Growth Factors/chemistry/metabolism. Related in: ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4384349_12885_2015_1130_Fig3_HTML&req=4
Transition of the GH receptor TMDsThe interaction of th | Open-i
Protein Binding. *Protein Interaction Domains and Motifs. *Protein Multimerization. *Receptor Cross-Talk ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4325515_bj2014-1293i003&req=4