A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or ... While many perform the same or similar biological roles, some isoforms have unique functions. A set of protein isoforms may be ... MeSH entry protein isoforms Definitions Isoform (CS1 errors: missing periodical, Articles with short description, Short ... isoforms represent functional protein products, and the structure of most isoforms in the human proteome has been predicted by ...
The protein products of the three Ras genes are almost identical. However, for reasons that remain unclear, KRAS is far more ... We suggest that in most cases, being the most abundant Ras isoform correlates with occupying the sweet-spot and that HRAS and ... We have quantified HRAS, NRAS, KRAS4A and KRAS4B protein abundance across a large panel of cell lines and healthy tissues. We ... Our data provide support for the model of a sweet-spot of Ras dosage mediating isoform-specific contributions to cancer and ...
RefSeq protein isoforms See 8 reference sequence protein isoforms for the NEIL2 gene. ... endonuclease 8-like 2 isoform a [Homo sapiens] endonuclease 8-like 2 isoform a [Homo sapiens]. gi,21450800,ref,NP_659480.1, ... LSBio NEIL2 Proteins [LifeSpan BioSciences, Inc.] LSBio NEIL2 Proteins. LifeSpan BioSciences, Inc. ... Transcript/Protein Information [PANTHER Classification System] Transcript/Protein Information. PANTHER Classification System ...
Fanconi anemia group C protein isoform a [Homo sapiens] Fanconi anemia group C protein isoform a [Homo sapiens]. gi,56118236, ... RefSeq protein isoforms See 40 reference sequence protein isoforms for the FANCC gene. ... Fanconi anemia group C protein isoform a [Homo sapiens]. NCBI Reference Sequence: NP_000127.2 ... Transcript/Protein Information [PANTHER Classification System] Transcript/Protein Information. PANTHER Classification System ...
... and signaling networks of RAS family proteins beyond RAS isoforms ... Proto-Oncogene Proteins p21(ras) / chemistry * Proto-Oncogene ... Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoforms Crit Rev Biochem Mol ...
Detection and identification of protein isoforms using cluster analysis of MALDI-MS mass spectra. Abstract: We describe an ... The output is presented as dendrograms in which protein isoforms cluster together. Clustering could be applied to mass spectra ... of MALDI-MS mass spectra for protein isoforms separated on two-dimensional electrophoresis gels. Mass spectra are matched ... Shared peak masses in a cluster could be identified and were used to create novel peak mass lists suitable for protein ...
... isoform H (fruit fly). Find diseases associated with this biological target and compounds tested against it in bioassay ... Protein target information for Nicotinic acetylcholine receptor alpha4, ...
Results-The PKC α, β1, β2, δ, ξ, and ζ isoforms were localized within the fibers of equine skeletal muscle. In addition, PKC α ... For some PKC isoforms, distribution was specific for fiber type. Staining of cell membranes for PKC α was observed ... Cryosections of equine muscle were stained with PKC isoform (α, β1, β2, δ, ξ, or ζ)-specific polyclonal antibodies and examined ... Conclusions and Clinical Relevance-Results indicated that PKC isoforms are expressed in equine skeletal muscle in a fiber type- ...
Protein target information for Protein fantom isoform X1 (pig). Find diseases associated with this biological target and ...
... Defining the Molecular Mechanisms of Lyssavirus Replication and Immune Evasion: the P protein Axis. Moseley, G., Gooley, P. R ... Viral targeting of STAT proteins: roles in disease. Moseley, G. & Sugiyama, M. ...
Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and Relative-of-WOC to regulate gene expression ...
At both the mRNA and protein levels, most AKR isoforms were highly expressed in the upper regions of the intestine, namely, the ... In this study, we evaluated the mRNA and protein expression levels of 12 AKR isoforms (AKR1A1, AKR1B1, AKR1B10, AKR1B15, AKR1C1 ... we comprehensively determined the mRNA and protein expression profiles of AKR and SDR isoforms involved in xenobiotic ... Expression of AKR and SDR Isoforms in the Human Intestine. Keiya Hirosawa, Hijiri Fujioka, Gaku Morinaga, Tatsuki Fukami, Naoki ...
muscle, troponin, troponin-I, troponin-T, myofibrillar protein, isoform, innervation, neuromuscular junction, synapse, crayfish ... Analysis of myofibrillar proteins in opener muscles. Regional differences in the isoform compositions of claw and leg opener ... Myofibrillar protein isoform expression is correlated with synaptic efficacy in slow fibres of the claw and leg opener muscles ... Analysis of myofibrillar isoforms showed that levels of troponin-T1 (TnT1), a 55 kDa isoform expressed in slow-tonic (S2) ...
Isoform-Specific Regulation of 5′ AMP-Activated Protein Kinase in Skeletal Muscle From Obese Zucker (fa/fa) Rats in Response to ... Woods A, Salt I, Scott J, Hardie DG, Carling D: The α1 and α2 isoforms of the AMP-activated protein kinase have similar ... Virkamäki A, Ueki K, Kahn CR: Protein-protein interactions in insulin signaling and the molecular mechanisms of insulin ... Exercise induces isoform-specific increase in 5′ -AMP-activated protein kinase activity in human skeletal muscle. Biochem ...
Individual isoforms of the protein kinase C (PKC) family of kinases may have assumed distinct responsibilities for the control ... actin appears to be a bifunctional anchoring protein that is specific for the PKC epsilon isoform. The assembly of this isoform ... Individual isoforms of the protein kinase C (PKC) family of kinases may have assumed distinct responsibilities for the control ... Identification and localization of an actin-binding motif that is unique to the epsilon isoform of protein kinase C and ...
DEAF1 protein, human * DNA-Binding Proteins * Nuclear Proteins * Protein Isoforms * Transcription Factors ... Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 ... We identified an equivalent variant Deaf1 isoform in the PLNs of patients with type 1 diabetes. Both the NOD mouse and human ... Deaf1 variant isoforms suppressed PTA expression by inhibiting the transcriptional activity of canonical Deaf1. Lower PTA ...
Theoretical isoforms. A protein isoform, or "protein variant",[1] is a member of a set of highly similar proteins that ... A protein isoform is a version of a protein with only small differences to another isoform of the same protein. Different forms ... It has been estimated that ~100,000 expressed sequence tags (ESTs) can be identified in humans.[1] Isoforms at the protein ... Protein A, B and C are isoforms encoded from the same gene through alternative splicing.. ...
Cryptic promoters in yeast drive alternative protein isoforms. Posted on November 19, 2019. by vicent ... Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast. Wei W, Hennig BP, ... paper finally out in Genome Research describing how many cryptic promoters drive in fact the expression of alternative proteins ...
Sequential activation of protein kinase C isoforms by organic dust is mediated by tumor necrosis factor. / Wyatt, Todd A.; ... Sequential activation of protein kinase C isoforms by organic dust is mediated by tumor necrosis factor. American journal of ... Sequential activation of protein kinase C isoforms by organic dust is mediated by tumor necrosis factor. In: American journal ... Sequential activation of protein kinase C isoforms by organic dust is mediated by tumor necrosis factor. ...
BLAST of Immunoglobulin domain-containing-like protein isoform 1 vs. TrEMBL Match: A0A158RAF4 (Uncharacterized protein OS= ... BLAST of Immunoglobulin domain-containing-like protein isoform 1 vs. Ensembl Nematostella Match: EDO41500 (Predicted protein [ ... BLAST of Immunoglobulin domain-containing-like protein isoform 1 vs. TrEMBL Match: A0A074ZMZ4 (Uncharacterized protein ( ... BLAST of Immunoglobulin domain-containing-like protein isoform 1 vs. UniProt/SwissProt Match: sp,Q6AZB0,BOC_MOUSE (Brother of ...
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short. Grouped By: Sequence identity 70% ...
Ras protein abundance correlates with Ras isoform mutation patterns in cancer *Fiona E. Hood ... GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation ... Epithelial specific splicing regulator proteins as emerging oncogenes in aggressive prostate cancer *Rahul Advani ... Functional inhibition of cancer stemness-related protein DPP4 rescues tyrosine kinase inhibitor resistance in renal cell ...
Protein Structure "Structural Basis for the SUMO2 Isoform Specificity of SENP7". 2 December, 2022. 2 December, 2022. ... SENP6 and SENP7 are the most divergent members of the family and they show a unique SUMO2/3 isoform preference and a particular ... Next Protein Folding and Conformational Diseases: "Development of a Highly Potent Transthyretin Amyloidogenesis Inhibitor: ... that is responsible for the SUMO2 isoform specificity. All the other interface contacts between SENP7 and SUMO2, including the ...
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガ ... Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. / Nishimoto, Yoshinori; Ito, ... Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. In: Journal of Biological ... Characterization of alternative isoforms and inclusion body of the
CREM Protein, alpha Isoform. CREM Protein, epsilon Isoform. CREM Protein, gamma Isoform. CREM Protein, tau Isoform. ICERIIgamma ...
Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells. / Mak, N. K.; Lung, H. L. ... Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells. In: Planta Medica. 2001 ... Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells. Planta Medica. 2001;67(5 ... Mak, NK, Lung, HL, Wong, RNS, Leung, HW, Tsang, HY & Leung, KN 2001, Expression of protein kinase C isoforms in euxanthone- ...
Protection of Centriole Engagement in Mitosis by Alternatively Spliced Shugoshin1 Isoforms in Complex with Protein Phosphatase ... Protection of Centriole Engagement in Mitosis by Alternatively Spliced Shugoshin1 Isoforms in Complex with Protein Phosphatase ... Eine alternativ gespleißte Isoform von Sgo1 lokalisiert ans Centrosom und nicht ans Centromer und wirkt auch dort. Inspiriert ... The challenges of this choreography might partly be met by dual use of the multi-protein complex cohesin in both sister ...
The human IL22RA2 gene co-produces three protein isoforms in dendritic cells [IL-22 binding protein isoform-1 (IL-22BPi1), IL- ... Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response. ... However, only IL-22BPi1 activates an unfolded protein response (UPR) resulting in increased protein levels of GRP78 and GRP94. ... bestowed similar characteristics on the resulting protein. We also found that CD14(++)/CD16(+) intermediate monocytes produced ...