Designing a valid randomized pragmatic primary care implementation trial: the my own health report (MOHR) project |...
Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. JAMA. ... patients are asked to select which topics they are ready to change and/or discuss with their doctor and select the one topic ... Table 1 summarizes the key characteristics of pragmatic trials compared to traditional efficacy trials in terms of measures, ... Trial status. The MOHR trial began January 2013 and is expected to complete data collection in November 2013. The trial is ...https://implementationscience.biomedcentral.com/articles/10.1186/1748-5908-8-73
Health Care Systems Research Collaboratory | Pain Consortium
As such, an initiative was created to fund pragmatic clinical trials demonstration projects. Of the seven phased project awards ... As such, an initiative was created to fund pragmatic clinical trials demonstration projects. Of the seven phased project awards ... Infographics on Pain Topics. Resource Library *Health Care Systems. Research Collaboratory. *Pain Registries ... A pragmatic trial is proposed to test the effectiveness of an evidence-based multidisciplinary pain management approach in the ...https://painconsortium.nih.gov/Resource_Library/HCSR_Collaboratory
Prevalence of adverse events (AEs) over time. AEs were | Open-i
Pragmatic Clinical Trials as Topic. *Treatment Outcome. *Young Adult. Related in: MedlinePlus ... To reflect clinical practice, exclusion criteria were limited to those in the product label. Efficacy was assessed using a ... To reflect clinical practice, exclusion criteria were limited to those in the product label. Efficacy was assessed using a ... Discussion: In real-world clinical practice, G-GR seems to be an effective, well-tolerated treatment option for patients with ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4257585_ajp-31-58-g009&req=4
OPUS at UTS: Pragmatic cluster randomised controlled trial of facilitated family case conferencing compared with usual care for...
Pragmatic Clinical Trials as Topic. en_US. dc.subject.mesh. Advance Care Planning. en_US. ... Its strengths and weaknesses will both lie in its pragmatic design. Trial registration: Australian New Zealand Clinical Trials ... Its strengths and weaknesses will both lie in its pragmatic design. Trial registration: Australian New Zealand Clinical Trials ... Design/Methods: A pragmatic parallel cluster randomised controlled trial design will be used. Twenty Australian nursing homes ...https://opus.lib.uts.edu.au/handle/10453/44985
Emollient bath additives for the treatment of childhood eczema (BATHE): multicentre pragmatic parallel group randomised...
... multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness BMJ 2018; 361 :k1332 ... 21 This trial was funded following a topic suggestion form submitted through the National Institute for Health Research website ... The BATHE trial was an adequately powered trial, with high follow-up rates and good adherence to trial intervention allocations ... multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness. BMJ 2018; 361 doi: https ...https://www.bmj.com/content/361/bmj.k1332
Pragmatic, Randomized Optimal Platelet and Plasma Ratios - Full Text View - ClinicalTrials.gov
Pragmatic, Randomized, Optimal Platelet and Plasma Ratios (PROPPR)is a Phase III trial designed to evaluate the difference in ... MedlinePlus related topics: Blood Transfusion and Donation Genetic and Rare Diseases Information Center resources: Acute ... Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: design, rationale and implementation. Injury. 2014 Sep; ... Enrolled in a concurrent, ongoing interventional, randomized clinical trial. *Patients who have activated the 'opt-out' process ...https://clinicaltrials.gov/ct2/show/NCT01545232?term=Blood+Transfusion&recr=Open&fund=01&rank=2
Primary Research~CCNM investigates a wide range of topics with leading researchers | CCNM
Randomized clinical trial to assess the effect of vitamin D on treatment resistant depression A large multi-centred trial that ... Pragmatic clinical trial to assess the addition of naturopathic medicine to usual care in the management of type 2 diabetes. ... OICC and CCNM are collaborating with the Ottawa Hospital Research Institute on an 11-year pragmatic randomized clinical trial ... Randomized clinical trial to assess the effect of vitamin D on treatment resistant depression. A large multi-centred trial that ...https://www.ccnm.edu/research/primary-research
Carbon cost of pragmatic randomised controlled trials: retrospective analysis of sample of trials | The BMJ
10.06 tonnes, 12.8 % that of a clinical trial and the equivalent saving of. taking 27 cars off the road. From an environmental ... Carbon cost of pragmatic randomised controlled trials: retrospective analysis of sample of trials BMJ 2009; 339 :b4187 ... cost of pragmatic randomised controlled trials: retrospective analysis of. sample of trials. BMJ 2009;339:b4187. ... cost of pragmatic randomised controlled trials: retrospective analysis of. sample of trials. BMJ 2009;339:b4187. ...https://www.bmj.com/content/339/bmj.b4187/rapid-responses
Coming Soon: - Pragmatic Clinical Trials Unit
The topics covered include the importance of pragmatic trials in healthcare, designing interventions, randomisation, choosing ... This course is for anyone involved in the design, conduct, analysis or reporting of a pragmatic trials in the academic or NHS ... trial management, data collection, quality control, quality assurance, adverse event reporting, statistical analysis, trial ... Based on the book 'A Practical Guide to Cluster Randomised Trials in Health Services Research' by Sandra Eldridge and Sally ...http://www.qmul.ac.uk/pctu/courses-and-events/
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use - Full Text View - ClinicalTrials.gov
Patients randomized to the email arm will receive a health information prescription via email on a health care topic following ... Interventional (Clinical Trial) Actual Enrollment :. 907 participants. Allocation:. Randomized. Intervention Model:. Parallel ... MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use. The safety and scientific validity of this ... Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number): Coberly E, Boren SA, Mittal M, ...https://clinicaltrials.gov/show/NCT01050465?order=80
AmstatNews | Department of Statistics
... pragmatic clinical trials, and comparative effectiveness. The Alan Alda Center for Communicating Science conducted a workshop ... One-hour tutorials on diverse topics pertinent to the research, clinical development, and regulation of pharmaceuticals will be ... Did you ever wish you could use the accumulating data from your event-based clinical trial to reliably predict its future ... Prediction in Event-Based Clinical Trials Instructors: Daniel Heitjan and Gui-Shuang Ying ...https://www.stat.wisc.edu/aggregator/sources/1
PAR-14-182: Exploratory Clinical Trials of Mind and Body Interventions for NCCAM High Priority Research Topics (R34)
Exploratory Clinical Trials of Mind and Body Interventions for NCCAM High Priority Research Topics (R34) PAR-14-182. NCCIH ... clinical efficacy or effectiveness study, or a pragmatic trial. The data collected should be used to fill gaps in scientific ... Exploratory Clinical Trials of Mind and Body Interventions for NCCAM High Priority Research Topics (R34) ... The clinical significance and, when applicable, the biological relevance of the future clinical trial must be clearly stated. ...https://grants.nih.gov/grants/guide/pa-files/PAR-14-182.html
PAR-18-417: Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 - Clinical...
Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 - Clinical Trials ... and pragmatic trials). In addition, multi-site clinical trials require a companion Data Coordinating Center (DCC) application ( ... Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required ... Clinical Trial Planning Phase - Exploratory Clinical Trials (current FOA). To maximize the impact of Mind and Body clinical ...https://grants.nih.gov/grants/guide/pa-files/PAR-18-417.html
Pharmacovigilance - Wikipedia
Pragmatic Approaches (CIOMS V); Management of Safety Information from Clinical Trials (CIOMS VI); the Development Safety Update ... The CIOMS, a part of the WHO, is a globally oriented think tank that provides guidance on drug safety related topics through ... whereas a clinical trial case will typically be assessed for causality by the clinical trial investigator and/or the license ... The variables in a clinical trial are specified and controlled, but a clinical trial can never tell you the whole story of the ...https://en.wikipedia.org/wiki/Pharmacovigilance
A multicentre, pragmatic, parallel group, randomised controlled trial to compare the clinical and cost-effectiveness of three...
Based on the learning from a pilot study (ISRCTN 23294263), the BEEP trial is a multi-centre, pragmatic, parallel group, ... The BEEP randomised trial aims to improve patients' short and long-term outcomes from exercise. It will test the overall ... This trial will contribute to the evidence base for management of older adults with knee pain attributable to osteoarthritis in ... individually randomised controlled trial, with embedded longitudinal qualitative interviews. 500 adults in primary care, aged ...https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/1471-2474-15-254
Effectiveness of alternative listening devices to conventional hearing aids for adults with hearing loss: a systematic review...
Clinical Trials as Topic'[MeSH] OR Randomized Controlled Trial[pt] OR Controlled Clinical Trial[pt] OR Pragmatic Clinical Trial ... pt] OR Clinical Trial[pt] OR Observational Study[pt] OR Multicenter Study[pt] OR 'Non-Randomized Controlled Trials as Topic'[ ... ClinicalTrials.Gov and WHO International Clinical Trials Registry Platform (ICTRP) to identify published, completed but ... Retrospective or prospective studies, randomised controlled trials, non-randomised controlled trials, and before-after ...http://bmjopen.bmj.com/content/6/10/e011683
Anthem, HealthCore and Boehringer Ingelheim Initiate World's Largest Pragmatic Clinical Trial to Study People Living with COPD...
... is currently a topic of scientific debate. Results from the trial will be available in 2020. ... Anthem, HealthCore and Boehringer Ingelheim Initiate World's Largest Pragmatic Clinical Trial to Study People Living with COPD ... the world's largest ever pragmatic clinical trial in chronic obstructive pulmonary disease (COPD) to study how commonly ... We believe it is important that everyday health decisions are based not only on data from traditional clinical trials, but also ...https://www.healthcore.com/anthem-healthcore-boehringer-ingelheim-initiate-worlds-largest-pragmatic-clinical-trial-study-people-living-copd-real-world-setting/
PubMed, HSRProj, and ClinicalTrials.gov Search Strategies for Informing Comparative Effectiveness Research
pragmatic trial[tw] OR pragmatic trials[tw] OR practical clinical trial[tw] OR. pragmatic clinical trial [pt] OR "comparative ... OR clinical trial, phase iv [pt] OR clinicaltrials.gov [si] OR isrctn [si] OR randomized controlled trials as topic [mh]) OR ( ... The ClinicalTrials.gov search strategy includes Phase III or Phase IV clinical trials or observational studies with an active ... This CER Randomized Controlled Trials search strategy was developed to identify randomized clinical trials and related ...https://www.nlm.nih.gov/nichsr/cer/CER_search_strategies.html
A large pragmatic clinical trial of TXA in a heterogeneous group of surgical patients is needed to resolve the uncertainties ... What is already known on this topic. *. Small trials on the effect of tranexamic acid (TXA) on blood transfusion in surgical ... However, a need remains for a large pragmatic clinical trial of the effect of routine use of tranexamic acid in a heterogeneous ... To identify ongoing or unpublished trials we searched the WHO International Clinical Trials Registry Platform. We also examined ...http://www.bmj.com/content/344/bmj.e3054
A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and...
... the Trial Design and the approach taken within the funding provided. The PoCT Trial is regarded as a pragmatic RCT, evaluating ... The paper provides an overview of the Trial Design, the rationale for the research methodology chosen and how the Trial was ... The Point of Care Testing in General Practice Trial (PoCT Trial) was an Australian Government funded multi-centre, cluster ... clinical effectiveness, cost effectiveness and satisfaction of PoCT in a GP setting. The PoCT Trial covered an 18 month period ...https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-9-50
Routine Prescription Feedback and Peer Comparison to Lower Antibiotic Prescriptions in Primary Care - Full Text View -...
Design: Randomized, controlled, pragmatic intervention trial. Setting: Primary care providers of Switzerland above the median ... A Randomized Clinical Trial. JAMA Intern Med. 2017 Feb 1;177(2):176-183. doi: 10.1001/jamainternmed.2016.8040. ... MedlinePlus related topics: Antibiotics U.S. FDA Resources Further study details as provided by University Hospital, Basel, ... rationale and design of a nationwide pragmatic randomized trial. BMC Infect Dis. 2016 Aug 17;16:421. doi: 10.1186/s12879-016- ...https://clinicaltrials.gov/ct2/show/NCT01773824?recr=Open&cond=%22Common+Cold%22&rank=17
Web-Based and Tailored Asthma Management Intervention (Puff City) in Teens With Asthma Attending Urban Clinics - Full Text View...
... and enriched pragmatic efficacy trial of an online asthma management program. Contemp Clin Trials. 2014 May;38(1):19-27. doi: ... will be evaluated as a clinical tool by initiating the web-based behavioral intervention of asthma management in a clinical ... MedlinePlus related topics: Asthma U.S. FDA Resources Further study details as provided by Dr. Mei Lu, Henry Ford Health System ... Pragmatic Randomized Controlled Trial of the Web-Based Asthma Management Intervention (Puff City) in Teens With Asthma ...https://clinicaltrials.gov/ct2/show/NCT01757002?term=asthma+%5BCONDITION%5D+AND+child+%5BAGE-GROUP%5D&recr=Open&rank=9
Vaasa Childhood Obesity Primary Prevention Study - Full Text View - ClinicalTrials.gov
Mustila T, Raitanen J, Keskinen P, Saari A, Luoto R. Pragmatic controlled trial to prevent childhood obesity in maternity and ... MedlinePlus related topics: Children's Health U.S. FDA Resources Further study details as provided by Taina Mustila, ... Mustila T, Keskinen P, Luoto R. Behavioral counseling to prevent childhood obesity--study protocol of a pragmatic trial in ... Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00970710 ...https://clinicaltrials.gov/ct2/show/NCT00970710
Engagement in Health Research Literature Explorer | PCORI
Three approaches to glucose monitoring in non-insulin treated diabetes: a pragmatic randomized clinical trial protocol. BMC ... Research Topic/Agenda (348) Apply Research Topic/Agenda filter *Results Review/Analysis (332) Apply Results Review/Analysis ... Advisory Panel on Clinical Trials*Biographies - Advisory Panel on Clinical Trials. *Advisory Panel on Clinical Trials ... Three approaches to glucose monitoring in non-insulintreated diabetes: a pragmatic randomized clinical trial protocol. ...https://www.pcori.org/literature/engagement-literature
PAR-18-118: NCCIH Mind and Body Clinical Trial Cooperative Agreement (U01 Clinical Trial Required)
NCCIH Mind and Body Clinical Trial Cooperative Agreement (U01 Clinical Trial Required) PAR-18-118. NCCIH ... and pragmatic trials). In addition, multi-site clinical trials require a companion Data Coordinating Center (DCC) application ( ... Applications proposing research topics not identified above as high programmatic priority will be considered of lesser or low ... Clinical Trial Planning Phase - Exploratory Clinical Trials (R34, PAR-14-182). To maximize the impact of Mind and Body clinical ...https://grants.nih.gov/grants/guide/pa-files/PAR-18-118.html