*  Antievolution.org - Antievolution.org Discussion Board -Topic::Evolutionary Computation
This limit implies that a single point mutation can increase total biological functionality by as much as 0.1%. In a genome ... For deleterious mutations, since lethal mutations exist, we choose dsf del = -1.. For favorable mutations, we allow the user to ... For deleterious mutations, since lethal mutations exist, we choose dsf del = -1.. For favorable mutations, we allow the user to ... This can be a point of discussion.. In regrad to your own experiments, I would like to point out that. biologists realize that ...
  http://www.antievolution.org/cgi-bin/ikonboard/ikonboard.cgi?s=50a399b6a4631568
*  CiNii 論文 - A Novel Somatic Point Mutation of the RET Proto-oncogene in Tumor Tissues of Small...
A Novel Somatic Point Mutation of the RET Proto-oncogene in Tumor Tissues of Small Cell Lung Cancer Patients * * FUTAMI ... A novel point mutation of the RET proto-oncogene in small cell lung carcinoma cell lines FUTAMI H. ... Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease ROMEO G. ... Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related ...
  https://ci.nii.ac.jp/naid/10008071241
*  Biology-Online • View topic - Polymorphism and Mutation
A mutation is a change to a single individual that may or may not be propagated. For example a single point mutation where a ... I suppose a mutation may become a polymorphism if its success allows it to spread within a population! ... Polymorphism and Mutation. Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures ... Polymorphism and Mutation. by Helics » Tue Mar 04, 2014 4:33 pm ... is the difference between Gene Polymorphism and Gene Mutation ...
  http://www.biology-online.org/biology-forum/about38000.html?p=161483&hilit=Population
*  BIS101 HW6 F08 Engebrecht - Deletions x Point mutations 1 2 3 4 5 1 2 3 4 5 1 a 2 b 3 c 4 d 5 e 2 The following DNA is part of...
Deletions x Point mutations 1 2 3 4 5 1 2 3 4 5 1 - - - - + a + - - + + 2 - - + + b + + - + - 3 - - - c - + - - + 4 - + d ... Five different point mutations were then tested in the same way for their ability to recombine with the five deletions. These ... Please draw a linear map representing the order and overlap of the deletions and the positions of the point mutations. ... BIS101 HW6 F08 Engebrecht - Deletions x Point mutations 1 2.... This preview shows document pages 1 - 2. Sign up to view the ...
  https://www.coursehero.com/file/5991661/BIS101-HW6-F08-Engebrecht/
*  13425 (Compute mutation type of a ClusterSeed or ClusterQuiver) - Sage
So I am happy to go ahead and give a positive review at this point. ... quiver.mutation_type._mutation_type_test Failed example: _mutation_type_test(2) # long time Expected: True ('A', 2) True ('A ... quiver.mutation_type._mutation_type_test Failed example: _mutation_type_test(3) # long time Expected: True ('A', 3) True ('A ... quiver.mutation_type._mutation_type_test Failed example: _mutation_type_test(4) # long time Expected: True ('A', 4) True ('A ...
  https://trac.sagemath.org/ticket/13425
*  Mutation and Cancer: The Antecedents to Our Studies of Adaptive Mutation | Genetics
... fact that although the cells in most cancers contain many point mutations they do not show a raised rate of point mutations ... Two mutations (or classes of mutations) are measured: A-mutations and B-mutations. In the low mutators, they occur at ... rate-limiting mutations (Cairns 1981). Shortly after this, human cancer cells were found to contain point mutations in the ... Point mutations in the normally cryptic ebgA gene of E.coli have been reported to behave rather like the aralac fusion because ...
  http://www.genetics.org/content/148/4/1433
*  Absence of point mutation in the third intracellular loop of...
Absence of point mutation in the third intracellular loop of alpha 1B- and alpha 1D adrenergic receptor in the aortae of ... Absence of point mutation in the third intracellular loop of alpha 1B- and alpha 1D adrenergic receptor in the aortae of ... According to the constitutive activity hypothesis for G-protein coupling receptors, we inferred that point mutations might ... and alpha 1D-AR induced by point mutations of the third intracellular loop of the genes. See more ...
  https://www.mysciencework.com/publication/show/absence-point-mutation-third-intracellular-loop-alpha-1b-alpha-1d-adrenergic-receptor-aortae-spontaneously-hypertensive-9e5fad97
*  Point mutation - Wikipedia
Point mutations may arise from spontaneous mutations that occur during DNA replication. The rate of mutation may be increased ... Point mutations in multiple tumor suppressor proteins cause cancer. For instance, point mutations in Adenomatous Polyposis Coli ... mutation in the deoxyribonucleic acid (DNA) that occurs at one point. Point mutations usually take place during DNA replication ... a mutation called a frameshift mutation). Point mutations that occur in non-coding sequences are most often without ...
  https://en.wikipedia.org/wiki/Point_mutation
*  Familial Parkinson's point mutation abolishes multiple system atrophy prion replication | PNAS
Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Amanda L. Woerman, Sabeen A. Kazmi, ... Familial Parkinson's point mutation abolishes multiple system atrophy prion replication Message Subject (Your Name) has sent ... To investigate this hypothesis, we infected cell lines expressing PD-causing point mutations in α-synuclein with MSA patient ... This alteration is consistent with the inability of the A53T mutation to rescue the effects of the E46K mutation in vitro. ...
  http://www.pnas.org/content/115/2/409.full
*  Structural Consequences of Point Mutations in Nine Human HPRT Variants | SpringerLink
Davidson B.L., Palella T.D., Fujimori S., Kelley W.N. (1989) Structural Consequences of Point Mutations in Nine Human HPRT ... Genetic evidence for identical mutations in two partially deficient subjects. J. Clin. Invest. In Press (1988).Google Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5673-8_22
*  FLEx Inducible Point Mutation | Genetically Modified Models | genOway
FLEx: Inducible Point Mutation. TET On/Off Systems. IRES: Co-Expression Models. Quick Knockin: Rosa26 / Hprt. RMCE. ... FLEx: Inducible Point Mutation. FLEx technology allows scientists to induce the expression of a mutated gene or a reporter gene ... Access to time- and tissue-restricted point mutant models.. This technique has become the gold standard for the generation of ... With FLEx mice scientists can reproduce a particular pathology that is triggered by a mutation and that normally manifests in ...
  https://www.genoway.com/technologies/flex-inducible-point-mutation.htm
*  Reversed Enantiopreference of an omega-Transaminase by a Single-Point Mutation
A single-point mutation, V328A, turn the (S)-selective omega-transaminase into an (R)-selective enzyme. This switch in ... Reversed Enantiopreference of an omega-Transaminase by a Single-Point Mutation. Svedendahl, Maria KTH, School of Biotechnology ... By combining these mutations, five enzyme variants are created. The performance of these variants is explored using a model ...
  http://kth.diva-portal.org/smash/record.jsf?pid=diva2:374790
*  Aphid Thermal Tolerance Is Governed by a Point Mutation in Bacterial Symbionts
... Helen E Dunbar, Alex C. C Wilson,¤ Nicole R ... The first such mutation occurred in January 2001, and the same mutation recurred in October 2005 in a different line (Figure 3 ... and is about 1,000-fold higher than per-site estimates of mutation [22]. Furthermore a genome-wide screen of Buchnera mutations ... Under this scenario of mutation-selection balance, a frequency of 10% or more would imply an implausibly high mutation rate for ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC1847839/?lang=en-ca
*  A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration. | Sigma-Aldrich
A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.. [Satoshi Nojima ... In humans, mutations in Sema4A are thought to contribute to retinal degenerative diseases. Here we generate a series of knock- ... The F350C mutation results in abnormal localization of the Sema4A protein, leading to impaired endosomal sorting of molecules ... in mouse lines with corresponding mutations (D345H, F350C or R713Q) in the Sema4A gene and find that Sema4A(F350C) causes ...
  https://www.sigmaaldrich.com/catalog/papers/23360997
*  A novel NGFB point mutation, a phenotype study of heterozygous patients | Journal of Neurology, Neurosurgery & Psychiatry
... type V having a point mutation in the Nerve growth factor beta (NGFB) gene. The homozygous genotype gives disabling symptoms. ... Conclusions: The NGFB mutation in its heterozygous form results in a milder disease than in homozygots with a variable clinical ... Methods: 26 patients heterozygous for the NGFB-mutation (12 men, mean age 50 (13-90) years) were examined clinically and ... without the mutation served as controls in the clinical examination part. 23 of the heterozygotes were examined ...
  http://jnnp.bmj.com/content/early/2008/04/17/jnnp.2007.136051
*  A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit | JCB
A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit. Malini Vashishtha, Thomas ... The most surprising finding of this study is that a single point mutation in E1 substitutes for the specific cholesterol ... A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit ... Mutation Responsible for Cholesterol Independence. To define the mutation that confers srf cholesterol independence, we ...
  http://jcb.rupress.org/content/140/1/91
*  Escape From Repeat-Induced Point Mutation of a Gene-Sized Duplication in Neurospora crassa Crosses That Are Heterozygous for a...
REPEAT-INDUCED point mutation (RIP) is a unique mutational process that occurs in the sexual cycle of Neurospora crassa during ... 1994 The Neurospora transposon Tad is sensitive to repeat-induced point mutation (RIP). Genetics 138: 657-664. ... Escape From Repeat-Induced Point Mutation of a Gene-Sized Duplication in Neurospora crassa Crosses That Are Heterozygous for a ... In Neurospora crassa the ability of an ectopic gene-sized duplication to induce repeat-induced point mutation (RIP) in its ...
  http://www.genetics.org/content/157/4/1581
*  A Cav3.2 T-Type Calcium Channel Point Mutation Has Splice-Variant-Specific Effects on Function and Segregates with Seizure...
A Cav3.2 T-Type Calcium Channel Point Mutation Has Splice-Variant-Specific Effects on Function and Segregates with Seizure ... A Cav3.2 T-Type Calcium Channel Point Mutation Has Splice-Variant-Specific Effects on Function and Segregates with Seizure ... A Cav3.2 T-Type Calcium Channel Point Mutation Has Splice-Variant-Specific Effects on Function and Segregates with Seizure ... A Cav3.2 T-Type Calcium Channel Point Mutation Has Splice-Variant-Specific Effects on Function and Segregates with Seizure ...
  http://www.jneurosci.org/content/29/2/371/tab-article-info
*  Compact Sequencing: Fast and Sensitive Detection of Clinically Relevant Point Mutations in KRAS | SelectScience
This allows focus on clinically relevant point mutations in genes of interest, with reference to personalised medicine. ... Application Note: Compact Sequencing: Fast and Sensitive Detection of Clinically Relevant Point Mutations in KRAS. 13 December ... This allows focus on clinically relevant point mutations in genes of interest, with reference to personalised medicine. ...
  http://www.selectscience.net/application-notes/compact-sequencing-fast-and-sensitive-detection-of-clinically-relevant-point-mutations-in-kras/?artID=21264
*  Abstract 2751: Automatic DNA extraction system can improve the EGFR point mutation detection rate of liquid biopsy | Cancer...
As previously we reported, we have developed fully automatic high-sensitive point mutation detecting system named mutation- ... Abstract 2751: Automatic DNA extraction system can improve the EGFR point mutation detection rate of liquid biopsy. Chiho ... In terms of the epidermal growth factor receptor (EGFR) L858R point mutation detection, the sensitivity of 200-M, 200-A, 1000-A ... Automatic DNA extraction system can improve the EGFR point mutation detection rate of liquid biopsy [abstract]. In: Proceedings ...
  http://cancerres.aacrjournals.org/content/77/13_Supplement/2751
*  A novel strategy for point mutation biomarker discovery in the colorectal cancer genome with massively parallel resequencing |...
As a solution, we describe the development and application of a novel resequencing strategy for point mutation discovery on a ... A novel strategy for point mutation biomarker discovery in the colorectal cancer genome with massively parallel resequencing. ... A novel strategy for point mutation biomarker discovery in the colorectal cancer genome with massively parallel resequencing ... For example, mutations in APC, KRAS and TP53 are critical to the development of colorectal cancer. Mutations in genes like EGFR ...
  http://cancerres.aacrjournals.org/content/67/9_Supplement/3799
*  Fundus Autofluorescence in Macular Dystrophy associated with Mitochondrial DNA Nucleotide A3243G Point Mutation | IOVS | ARVO...
Abstract: : Purpose: The mitochondrial DNA point mutation 3243, which is responsible for maternally inherited diabetes and ... Fundus Autofluorescence in Macular Dystrophy associated with Mitochondrial DNA Nucleotide A3243G Point Mutation ... Fundus Autofluorescence in Macular Dystrophy associated with Mitochondrial DNA Nucleotide A3243G Point Mutation ... Fundus Autofluorescence in Macular Dystrophy associated with Mitochondrial DNA Nucleotide A3243G Point Mutation . Invest. ...
  http://iovs.arvojournals.org/article.aspx?articleid=2421589
*  Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor. | Broad...
Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor.. ... We show that the point mutation prevents the formation of the mature form of PCSK9 by hindering folding, reducing the rate of ... Amino Acid Substitution, Humans, Peptides, Point Mutation, Proprotein Convertase 9, Protein Binding, Protein Domains, Protein ... A PCSK9 loss-of-function point mutation (Q152H) that reduces LDLc levels two-fold was identified in a patient population. LDLc ...
  https://www.broadinstitute.org/publications/broad10146
*  CiNii 論文 - EGFR point mutation in non-small cell lung cancer is occasionally accompanied by a...
EGFR point mutation in non-small cell lung cancer is occasionally accompanied by a second mutation or amplification * * ... EGFR mutations in non-small-cell lung cancer : analysis of a large series of cases and development of a rapid and sensitive ... Mutations of the epidermal growth factor receptor gene in lung cancer : biological and clinical implications KOSAKA T ... EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to ...
  https://ci.nii.ac.jp/naid/10018768298
*  LaPerm - Die Katze mit den Dauerwellen: TICA-Rasse-Standard
Then came a straight-coated red point male kitten named Snow Fire who changed the rules. As his bald littermates grew curly ... tabby cat named Speedy have a litter of 6 kittens in a barn in her cherry orchard and witnessed the birth of a new rex mutation ...
  http://laperm.at/index.php?id=8