Phosphoramides are a class of phosphorus compounds with the formula O=P(NR2)3-n(OH)n. They can be considered derivatives of ... Phenyl phosphorodiamidate, a phosphoramide but also a phosphate ester, is used in agriculture to enhance the effectiveness of ... In practise the term is commonly confined to the phosphoric triamides (P(=O)(NR2)3), essentially phosphoramide and derivatives ...
Taxonomic hierarchy of Class phosphoramides [P(=O)(NR2)3]. Display of synonyms, alternative taxonomic positions, references, ...
Hexamethyl phosphoramide *. 680-31-9. TD0875000. Hexamethylene. 110-82-7. GU6300000. Hexamethylene diisocyanate *. 822-06-0. ...
Using a model ovotoxic alkylating drug, cyclophosphamide (CPA), and its active metabolite, phosphoramide mustard (PM), we ... Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ... Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ... Using a model ovotoxic alkylating drug, cyclophosphamide (CPA), and its active metabolite, phosphoramide mustard (PM), we ...
Hexamethyl phosphoramide / Hexaméthylphosphoramide [680-31-9]. (L). Skin / Peau. Hexyl acetate (isomeric mixture) / Acétate ...
Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs. Hu L ...
Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat. Cancer ...
Siobhan Rice - Descriptive Study of the Effects of Phosphoramide Mustard on the Testis ...
Aldophosphamide can undergo B-elimination to form active metabolites phosphoramide mustard and acrolein. This spontaneous ...
Acrolein and phosphoramide are the active compounds, and they slow the growth of cancer cells by interfering with the actions ... In order to work, cyclophosphamide first is converted by the liver into two chemicals, acrolein and phosphoramide. ...
Phosphoramides [D02.705.672] * Hempa [D02.705.672.249] * Phosphoramide Mustards [D02.705.672.500] * Cyclophosphamide [D02.705. ... Phosphoramide Mustards Preferred Term Term UI T031785. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1979). ... Phosphoramide Mustards Preferred Concept UI. M0016714. Registry Number. 0. Scope Note. A group of nitrogen mustard compounds ... Phosphoramide Mustards. Tree Number(s). D02.455.526.728.650.730. D02.705.672.500. Unique ID. D010752. RDF Unique Identifier. ...
Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. ... Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ... Involvement of a volatile metabolite during phosphoramide mustard-induced ovotoxicity. Toxicol Appl Pharmacol. 2014;277:1-7. ... The acylic tautomer of 4-hydroxycyclophosphamide is then cleaved non-enzymatically into phosphoramide mustard which is the ...
In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecules characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions regardless of the rest of the molecules composition.[1][2] This enables systematic prediction of chemical reactions and behavior of chemical compounds and the design of chemical synthesis. The reactivity of a functional group can be modified by other functional groups nearby. Functional group interconversion can be used in retrosynthetic analysis to plan organic synthesis. A functional group is a group of atoms in a molecule with distinctive chemical properties, regardless of the other atoms in the molecule. The atoms in a functional group are linked to each other and to the rest of the molecule by covalent bonds. For repeating units of polymers, functional groups attach to their nonpolar core of carbon atoms and thus add chemical character to carbon chains. Functional groups ...
OH) and hydroxyls interact strongly with each other. Plus, when functional groups are more electronegative than atoms they attach to, the functional groups will become polar, and the otherwise nonpolar molecules containing these functional groups become polar and so become soluble in some aqueous environment. Combining the names of functional groups with the names of the parent alkanes generates what is termed a systematic nomenclature for naming organic compounds. In traditional nomenclature, the first carbon atom after the carbon that attaches to the functional group is called the alpha carbon; the second, beta carbon, the third, gamma carbon, etc. If there is another functional group at a carbon, it may be named with the Greek letter, e.g., the gamma-amine in gamma-aminobutyric acid is on the third carbon of the carbon chain attached to the carboxylic acid group. IUPAC conventions call for numeric labeling of the position, e.g. 4-aminobutanoic acid. In traditional names various qualifiers are ...
A monomeric copper-phosphoramide complex: Synthesis, structure, and electronic properties, Polyhedron 118, 154 (2016). ...
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Phosphoramide mustard ⓑ Acrolein ⓒ Aldophosphamide ⓓ 4-hydroxy cyclophosphamide ➤ Phosphoramide mustard ...
Hexamethyl Phosphoramide. C6H18N3OP. inquiry. 168893-66-1. 2-Chloropyridine-5-Carbohydrazide. C7H9N3O. inquiry. ...
Efficient extraction of uranium from environmental samples using phosphoramide functionalized magnetic nanoparticles: ...
HEXAMETHYL PHOSPHORAMIDE 99%. 5G..$18. 100G..$39. 500G..$131. 50ML. 18. 610-99-1. 2,-HYDROXYPLOPHENONE 97%. 5G..$17. 25G..$23. ...
The crystal structure of diphenyl (benzylcarbamothioyl)phosphoramide, (C6H5O)2P(O)(NHC(S) NHCH2C6H5), is reported. In the P(O) ...
Carbazolyl-substituted phosphoramides as ligands for Mn(II) luminescent complexes 1-gen-2022 Marco BortoluzziJesus Castro ... Carbazolyl-substituted phosphoramides as ligands for Mn(II) luminescent complexes. 2022-01-01 Bortoluzzi, Marco; Castro, Jesus ...
This study aimed to determine whether the E-COD (E: etoposide 50 mg/m2/d, d1-3; C: phosphoramide 750 mg/m2, d1, d3; O: ...
162] Chiral Phosphoramide-Catalyzed Aldol Additions of Ketone Enolates. Preparative Aspects (with R. A. Stavenger, K.-T. Wong ... 164] Solid State and Solution Structural Studies of Chiral Phosphoramide-Tin Complexes Relevant to Lewis Base Catalyzed Aldol ... 160] Synthesis of Phosphoramides for the Lewis Base-catalyzed Allylation and Aldol Addition Reactions (with X. Su, Y. ...
A Organic phosphorus phosphate, monothiophosphate, dithiophosphate, phosphonate, phosphoramide, thiophosphoramide, ...
Phosphoramide mustard and acrolein are active metabolites of CP (7). All anticancer effects of CP related to phosphoramide ...