*  postnatal lethality, complete penetrance Mammalian Phenotype Term (MP:0011085)
Links to summary annotated phenotype data at MGI are provided in Term Detail reports. ... The Mammalian Phenotype (MP) Ontology is a community effort to provide standard terms for annotating phenotypic data. You can ... Please contact us with any other questions about the Mammalian Phenotype Ontology.. This ontology is also used by the Rat ...
  http://www.informatics.jax.org/vocab/mp_ontology/MP:0011085
*  Cellular Phenotype Database
The Cellular Phenotype database provides easy access to phenotypic data derived from high-throughput screening, facilitating ... Search by «Any study term» provides results for phenotype terms through the studies having common genes knocked down.. Search ... by study acronim provides results for phenotype terms observed together for a given reagent/gene ...
  https://www.ebi.ac.uk/fg/sym
*  mcrBC phenotype
... Richard P. Grant see_sig at cmtech.co.delete.uk Tue Sep 22 09:45:46 EST 1998 *Previous message: iodine-125 in ...
  http://www.bio.net/bionet/mm/methods/1998-September/070451.html
*  Phenotype Image Detail
Hepatic lipid accumulation is observed in 5 month old male mice on a standard or high fat (HF) diet. A: Hematoxylin and eosin liver histology of wild type (WT) and Ppargtm1Lja/Pparg+ (KI) mice. Both macrovesicular and microvesicular fat depositions are observed in mutant mice on a HF diet. PV, peripheral vein; CV, central vein. B: Hepatic TG (triglyceride) content for wild type and mutant mice. The mean +/- standard deviation is presented for the four groups of 5 month old mal mice; n = 4 or 5 for each group ...
  http://www.informatics.jax.org/image/pheno/MGI:3797776
*  Phenotype Image Detail
Compared with the wild-type mouse (left), the Sox9tm2Crm/Sox9tm2Crm H2afvTg(Wnt1-cre)11Rth/0 skeleton shows obvious craniofacial deformities characterized as a domed skull and short snout. However, no abnormalities are seen in the trunk or limbs ...
  http://www.informatics.jax.org/image/pheno/MGI:3718201
*  Phenotype Image Detail
Gross morphology of Trip11Gt(AJ0490)Wtsi/Trip11Gt(AJ0490)Wtsi mutants. A: Image of a pair of E18.5 embryos. Note the open mouth and omphalocele (arrow) on the Trip11Gt(AJ0490)Wtsi/Trip11Gt(AJ0490)Wtsi (-/-) embryo. B: Cardiovascular defects in mutant mice. (Ba-Bb, wild-type (+/+)) EFIC images of a wild-type E18.5 embryo showing normal septation of the ventricular chambers (Ba), contrasting with the ventricular septal defect (VSD) seen in mutant embryo shown in (Bc). The aorta (Ao) connects with the left ventricle (LV) (Bb), which contrasts with the mutant embryo shown in (Bf) with an overriding aorta that connects to both ventricles via a VSD. (Bc-Be, mutant) EFIC images of a mutant embryo at E18.5. In the transverse imaging plane (Bc), a large muscular ventricular septal defect (white arrow) can be seen situated posteriorly. Examination in the frontal plane (Bd) showed a second muscular ventricular septal defect (white arrow) positioned anteriorly. Three dimensional reconstruction of the heart ...
  http://www.informatics.jax.org/image/MGI:3837660
*  Phenotype Image Detail
A: In adult Hsd11b2tm1Yko/Hsd11b2tm1Yko mice, the distal tubules (d) show considerable enlargement: the tubular diameter is increased threefold compared with the distal tubule in the wild-type mice (B). Note that the proximal tubules (p) and glomeruli (g) are unaffected in the mutant mice. C: Hyperplasia is apparent in the mutant mouse distal tubule (d), which shows over 20 cells in the cross-sectional profile compared with (D) the four to six cells observed in the wild-type. E: The distal tubular enlargement (d) is evident in mutant mice at the anatomical origin of the distal tubule at the juxtaglomerular apparatus (j) adjacent to the glomerulus (g), compared with (F) the nonenlarged wild-type distal tubule. md, macula densa. G: Proximal tubule (p) is normal in mutant kidneys. Mutant proximal tubules are indistinguishable from (H) wild-type proximal tubules. The tubules are of similar diameter and cell number in cross section. They are lined by cubiodal cells with granular cytoplasm and a brush ...
  http://www.informatics.jax.org/image/MGI:3822298
*  Phenotype Image Detail
Panel D. As compared to the +/+ wildtype (left), the Fgfr2tm4Lni/+ is characterized by a shorter face, domed skull and widely spaced protruding eyes. Panel E. +/+ wildtype (left) and perinatal lethal Fgfr2tm4Lni/Fgfr2tm4Lni (right). The Fgfr2tm4Lni/Fgfr2tm4Lni show discoloration of the skin, smaller size, shortened face, open eyelids and lack of milk spot ...
  http://www.informatics.jax.org/image/MGI:3706977
*  Phenotype Image Detail
Whole hearts and cardiac muscle sections. Hearts from 10 week old Destm1Cap/Destm1Cap (-/-, A) and wild type (WT, E) mice demonstrate extensive areas of degeneration and calcification throughout the myocardium of mutant mice. Sections from mutant mice (B and C) and corresponding areas in wild type (F and G) were stained with Masson's trichrome to reveal areas of interstitial fibrosis and degeneration. High magnification of cardiac myofibers taken from nonfibrotic regions of mutant myocardium (D) and wild type (H) myocardium stained with hematoxylin and eosin. Several of the fibers from the mutant myocardium appear to be disrupted and disintegrating. Bars: D and H, 5um; C and G, 10um ...
  http://www.informatics.jax.org/image/pheno/MGI:3800585
*  Phenotype Image Detail
A: The epidermis of the control and Slc27a4wrfr/Slc27a4wrfr appears similar, although the dermis appears more cellular in the Slc27a4wrfr/Slc27a4wrfr. At E17.5 the Slc27a4wrfr/Slc27a4wrfr epidermis is thicker with a flattened skin surface. At birth (PO) the Slc27a4wrfr/Slc27a4wrfr epidermis is on average three times thicker then the control (Bars indicate length), as well as having fewer and abnormally arranged keratohyalin granules (brackets). B: Staining for keratin 14 (K14) at E17.5 shows an increased thickness and flattening of the Slc27a4wrfr/Slc27a4wrfr. Keratin 6 (K6) is only express in the Slc27a4wrfr/Slc27a4wrfr. Loricrin (Lor) was not concentrated at the plasma membrane of granular cells in the Slc27a4wrfr/Slc27a4wrfr. C: E17.5 embryos incubated overnight show penetration into the Slc27a4wrfr/Slc27a4wrfr but not the control. D: Oil red O staining shows numerous fat droplets in the squamous layer of the Slc27a4wrfr/Slc27a4wrfr but not the control ...
  http://www.informatics.jax.org/image/MGI:3711745
*  Phenotype Image Detail
Histology of seminiferous tubules. Histological analyses of testicular sections of wild-type (+/+), Hsf1tm1Miv/Hsf1tm1Miv (hsf1-/-), Hsf2tm1Miv/Hsf2tm1Miv (hsf2-/-), or Hsf1tm1Miv/Hsf1tm1Miv Hsf2tm1Miv/Hsf2tm1Miv (hsf1-/- hsf2-/-) adult (12 weeks) mice. A: Paraffin-embedded sections were stained with H&E. Testes from Hsf2tm1Miv/Hsf2tm1Miv mice show seminiferous tubules with disruption of spermatogenesis (marked by arrow) such as reduction of spermatocytes and spermatids. Note the severe testicular tissue degeneration such as reduced number of spermatogonia, complete absence of developing spermatocytes and spermatids, tubular vacuolization, and formation of multinuclear giant cells (right panel, marked by arrow) in testes of double homozygous mice. Note the Sertoli cells visible at the basal layer in testes of double homozygous mice (right panel); no visible abnormalities were observed in testes of Hsf1tm1Miv/Hsf1tm1Miv or wild-type mice. Testicular sections were viewed at relatively low x200 ...
  http://www.informatics.jax.org/image/MGI:4819257
*  Phenotype Image Detail
D: The skeleton of a wild-type mouse (right) and Wwtr1tm1Whun/Wwtr1tm1Whun mouse (left) embryos stained with Alizarin red and Alcian blue to stain bone (red) and cartilage (blue), respectively. Note the slightly shorter skeleton of the homozygous mouse embryo. G & H: Hematoxylin and eosin staining of longitudinal kidney sections from 8 week old wild-type (G) and homozygous mutant mouse (H), showing numerous cysts in the corticomedullary region of the homozygous mouse kidney. Magnification: x20 ...
  http://www.informatics.jax.org/image/pheno/MGI:3715873
*  Phenotype Image Detail
Alizarin red S staining of the skeletons of newborn wild-type, Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju transgenic mice. Lateral view of skull, thoracic cage, and hindlimb; and frontal view of lumbar vertebra of a wild-type mouse (left), and a Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju (right) littermate. Abbreviations: supraoccipital bone (so); sternum (st); lumbar vertebrae (vt); ischium (is); pubic bone (pb); tibia (tb ...
  http://www.informatics.jax.org/image/pheno/MGI:3716957
*  Phenotype Image Detail
A-C: Appearance of control (CT) (A), Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 (Rxralpha beta ep-/-) (B), and Rxratm1Ipc/Rxratm4Ipc Rxrbtm1Mma/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 (RXRalpha betaepaf2o)(C) mice at week 5. Close views of the ears are shown in Insets. Black arrows in B and C point to regions with hair loss, and white arrowhead in B Inset points to the red and swollen ear. D-F: Hematoxylin and eosin staining of ear sections of CT (D), Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 (E), and Rxratm1Ipc/Rxratm4Ipc Rxrbtm1Mma/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 (F) at week 5. White arrows point to dermal-epidermal junction. hf, hair follicle; u, utriculi. Scale bar 50um ...
  http://www.informatics.jax.org/image/MGI:3777332
*  Phenotype Image Detail
a-f) Brain sections from Psen1tm1.1Tcs/Psen1tm1.1Tcs Tg(APPSWE)2576Kha/0 mice (a,b,c,e) and Tg(APPSWE)2576Kha/0 mice (d,f). Psen1tm1.1Tcs/Psen1tm1.1Tcs Tg(APPSWE)2576Kha/0 mice (3 (a), 6 (b) and 9 months (c,d) old) and 9-month-old single Tg(APPSWE)2576Kha/0 mice (d,f) were immunostained with the 4G8 antibody to amyloid beta (a-d) and antibody to GFAP (green) with 4G8 counterstaining (red) (e,f ...
  http://www.informatics.jax.org/image/pheno/MGI:5307266
*  Phenotype Image Detail
D-F: By 6 months, all mutant mouse eyes exhibit a clear phenotype characterized by slight swelling of peripupillary tissue. G-I ...
  http://www.informatics.jax.org/image/MGI:3773916
*  Phenotype Image Detail
Analysis of Tsc2tm1Djk/Tsc2tm1Djk embryos. A: Immunoblot analysis demonstrating lack of tuberin expression in Tsc2tm1Djk/Tsc2tm1Djk (-/-) embryos using mAb 5E8. B: Gross anatomy of homozygous mutant embryos. C-F: Histology of mutant (C and E) and wild type (D and F) embryos. C and D: Full embryo section, identical magnification. Insets indicate area of view enlarged in E and F. E and F: Liver and adjacent organs, identical magnification. H, heart; L, liver. The mutant embryo is overall smaller, and the liver is markedly hypoplastic with dilated sinusoids (arrows) in contrast to the normal liver. Scale bars: B-D, 2mm; E and F, 200um ...
  http://www.informatics.jax.org/image/pheno/MGI:3798291
*  Phenotype Image Detail
Wild-type (right) Kcnq1tm1Kpfe/Kcnq1tm1Kpfe (left) comparisons of the midmodular sections of the cochlea at P0 (A), P3 (B) and P70 (C). Note the collapse of Reissner's membrane at P3 (B) and degeneration of inner and outer hair cells at P70 (C). D-F: Details of the saccule at P0 (D), P8 (E) and P70 (F ...
  http://www.informatics.jax.org/image/pheno/MGI:3716126
*  Phenotype Image Detail
A and B: Photographs of 17 day old wild-type (Lmna+/+, A) and Lmnatm1Lgf/Lmnatm1Lgf (LmnaHG/HG, B) mice. The mutant mouse had a spontaneous fracture in the left forelimb (red arrow). C-F: Surface renderings of microCT scans of the skull (performed at exactly the same threshold) for a 17 day old mutant mouse (D and F) and littermate wild-type mouse (C and E). C and D: Top view of skulls. The mutant skull is misshapen, poorly mineralized, and exibits incomplete fusion of the cranial sutures (red arrow). E and F: Lateral view of skulls. The mutant skull is misshapen, with a small mandible (upper red arrow) and a short lower incisor (lower left arrow ...
  http://www.informatics.jax.org/image/pheno/MGI:3818324
*  Phenotype Image Detail
Photograph of incisor teeth from wild-type (A) and Amelxtm1Kul/Amelxtm1Kul (B). Scanning electron micrograph showing a smooth enamel surface for wild-type (C) and marked enamel hypoplasia characterized by a furrowing of the enamel in the incisor from a mutant mouse (D ...
  http://www.informatics.jax.org/image/pheno/MGI:3808900
*  Workshop: The Neuronal Phenotype
... Denes V. Agoston vagoston at helix.nih.gov Tue Mar 23 10:30:49 EST 1993 *Previous message: ... The neuronal phenotype: molecular genetics, cell specification, plasticity and therapeutical frontiers'. August 29-September 3 ... Maintanance and plasticity of neurotransmitter phenotypes; 6.Therapeutical frontiers Partial list of speakers: Campos-Ortega, ...
  http://www.bio.net/bionet/mm/neur-sci/1993-March/011914.html
*  phenotype of the day
... A Mayan discovery Posted July 17, 2012 by mangrist in bottom up, Here is a Human Bean, phenotype of the ... Phenotype of the day Posted February 3, 2012 by mangrist in bottom up, phenotype of the day ... Posted June 4, 2012 by mangrist in Me Me Me, Personal Genomics, phenotype of the day, the subject of humans, When I'm in the ...
  http://blogs.plos.org/genomeboy/category/phenotype-of-the-day/
*  What is an extended phenotype? | Reference.com
The idea of an extended phenotype refers to the expression of genes in the behavior of an organism rather than its physical ... What is an intermediate phenotype?. A: An intermediate phenotype describes an organism that displays a blend of the phenotypic ... Can you provide an example of a phenotype and a genotype?. A: An example of a genotype is an organism's blood type, while an ... A: An incomplete dominance Punnett square is a diagram that predicts the outcome of genotype as well as phenotype in organisms ...
  https://www.reference.com/science/extended-phenotype-ac8d5c7694f9678d
*  Haptoglobin Phenotype and Gestational Diabetes | Diabetes Care
GDM and Hp phenotype. GDM occurred only rarely in the Hp1-1 phenotype group (n = 8; 7%) and was more frequent in Hp2-1 group (n ... B: Hp phenotype as an independent risk factor for GDM. The ORs to develop GDM for carriers of the Hp2-1 and Hp2-2 phenotypes, ... Hp phenotype and GDM (n = 250). A: Association of the Hp phenotype with impaired glucose tolerance. Distribution of Hp ... Electropherogram with typical Hp phenotype patterns, as observed in serum samples. SDS-PAGE of Hp. Hp phenotypes: Hp1-1 (lane 8 ...
  http://care.diabetesjournals.org/content/27/9/2103
*  Genetic Determinants of Pollen Phenotype: Ingenta Connect
Competition among a vast number of pollen grains for a limited number of ovules creates the opportunity for very intense natural selection. Such selection, intensified by microbial-like characteristics in the pollen, gains significance from the fact that much of the plant (diplophase) structural genome is expressed in the pollen. As a result of this intense selection, pollen exhibits extremely rapid reactions upon a compatible stigma, releasing large fractions of its total protein content within minutes. These proteins are derived from both haplo- and diplo-phase cells. The first compounds released are relatively invariant and may serve to initiate species recognition reactions ...
  http://www.ingentaconnect.com/content/ocean/aap/1982/00000003/00000002/art00009