Peptidyl-dipeptidase B - Wikipedia
Peptidyl-dipeptidase B (EC 3.4.15.4, dipeptidyl carboxyhydrolase, atriopeptin convertase, atrial di-(tri)peptidyl ... Peptidyl-dipeptidase+B at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (Articles with ... carboxyhydrolase, peptidyldipeptidase B, atrial dipeptidyl carboxyhydrolase, atrial peptide convertase) is an enzyme. It ...
Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure
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ACE polymorphisms. - Oxford Big Data Institute
Angiotensin converting enzyme (ACE) plays an essential role in two physiological systems, one leading to the production of angiotensin II and the other to the degradation of bradykinin. The wide distribution and multifunctional properties of these peptides suggest that ACE could be involved in various pathophysiological conditions. The discovery that ACE levels are under genetic control ushered in a new era of investigation; most studies focused on an insertion/deletion (I/D) polymorphism in intron 16 of the ACE gene as a marker for a functional polymorphism. Recently, many single nucleotide polymorphisms were detected in the gene and the search for the locations of functional polymorphisms became a topic of extensive investigation. Nevertheless, association studies on the I/D polymorphism and clinical outcomes continued, mostly with conflicting results. This article reviews the current state of knowledge regarding ACE polymorphisms and suggests that a functional polymorphism is ...