Impact of intrapeptide epitope location on CD8 T cell recognition: implications for design of overlapping peptide panels. -...
... of peptide-binding motifs. A CD8 T cell response to an epitope within a longer peptide is best detected when the epitope is ... cytomegalovirus and influenza and in peptide-binding motifs. Recognition of known epitopes within longer synthesized peptides ... The effect of epitope location within such peptides is not known but may influence recognition. OBJECTIVE: To examine if ... The impact was examined of epitope location within overlapping peptides on recognition of epitope-specific CD8 T cell responses ...https://www.paediatrics.ox.ac.uk/publications/191121
Patent US6074689 - Colonic delivery of protein or peptide compositions - Google Patents
Also disclosed is a composition for delivering an active protein or peptide to the colon, the composition being produced by the ... the active protein or peptide comprising from about 50% to about 95% of the batch size (weight/weight) and the microcrystalline ... providing a homogenous mixture of the active protein or peptide and microcrystalline cellulose, both in dry form, ... Disclosed is a method for delivering an active protein or peptide to the colon. The steps of the method include providing a ...http://www.google.com/patents/US6074689?dq=6,049,612
As shown below, the peptide array is directly synthesized on a membrane with a maximum capacity of 384 peptide dots. The ... followed by immunoblotting to find the interaction between the target protein and selective peptide dots. The minimum peptide ... Selected peptide candidates will be linked with a membrane-permeable sequence (roughly 10 aa long) so that they can penetrate ... We have used this technique extensively to identify small peptide sequences (roughly 10 aa long) that can be applied for either ...http://www.primarypeptides.com/technology/peptide-array/
Viruses | Free Full-Text | How much of Virus-Specific CD8 T Cell Reactivity is Detected with a Peptide Pool when Compared to...
CEF peptide pool), we assessed peptide competition in PBMC from 42 human subjects. The magnitude of the peptide pool-elicited ... Peptides, when restricted by the same HLA allele, and presented from within the same peptide pool, can compete for HLA binding ... By studying the dose-response curves for individual CEF peptides, we show that several of these peptides are present in the CEF ... of the sum of the CD8 T cell responses elicited by the individual peptides. Therefore, while the effect of peptide competition ...http://mdpi.com/1999-4915/4/11/2636/xml
Global Industry Insights on Peptide Therapeutics Market Size, Share, Analysis, Growth, Trends and Forecast From 2012 To 2020 -...
Peptides differ from protein on the basis of size. The presence of amino acids in peptides is less than 55 molecules. Peptides ... As peptides act on cell membrane, so it helps peptides in treating various diseases. As the market has a huge potential, thus ... Among these, innovative peptides held the largest market share in 2013, as it is cost effective as compared to generic peptides ... Peptides are referred as amide bonds which are linked with small chains of amino acid monomers. "Peptide therapeutics market" ...http://www.meerutreporter.com/story/15635/global-industry-insights-on-peptide-therapeutics-market-size-share-analysis-growth-trends-and-forecast-from-2012-to-2020-hexa-research.html
Indian Patents. 240957:'A PEPTIDE THAT IS A MATURATION PRODUCT OF THE BASIC PROLIN-RICH LACRIMAL PROTEIN (BPLP)OR A PEPTIDE...
peptides and peptide derivatives as well as to antibodies directed against said. peptides and peptide derivatives thereof.. ... The peptides of the invention include "peptide derivatives".. The "peptides derivatives" are peptides having amino acid ... linear peptide or the side chains of amino acids within the peptide may be joined,. e.g., by a chemical bond. Such peptides ... Another peptide of the invention is the peptide that consists of sequence. YQRFSR (SEQ ID No. 4).. Still another peptide of the ...http://www.allindianpatents.com/patents/240957-a-peptide-that-is-a-maturation-product-of-the-basic-prolin-rich-lacrimal-protein-bplp-or-a-peptide-derivatives-thereof
EP 1064010 A1 20010103 - PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME
Specifically, the present invention is directed to a composition formulated from peptides which substantially correspond to ... Specifically, the present invention is directed to a composition formulated from peptides which substantially correspond to ... The present composition specifically includes the known chemical modification of the peptides described herein, specifically ... The present composition specifically includes the known chemical modification of the peptides described herein, specifically ...https://data.epo.org/gpi/EP1064010A1-PEPTIDE-COMPOSITIONS-AND-FORMULATIONS-AND-USE-OF-SAME
Lirias: PepX: a structural database of non-redundant protein-peptide complexes
Moreover, we provide an additional source of data for peptide design by annotating peptides with naturally occurring backbone ... providing a set of structurally diverse protein-peptide interactions. The final data set contains 505 unique protein-peptide ... Peptide-mediated interactions are a prime target for drug design because they are predominantly present in signaling and ... Although protein-peptide interactions are estimated to constitute up to 40% of all protein interactions, relatively little ...https://lirias.kuleuven.be/handle/123456789/292339
DSpace@MIT: A self-assembling peptide scaffold functionalized for use with neural stem cells
... and the mechanical properties of the peptide scaffolds were examined through theological analysis. The functionalized peptides ... A self-assembling peptide scaffold functionalized for use with neural stem cells. Research and Teaching Output of the MIT ... A self-assembling peptide scaffold functionalized for use with neural stem cells. Download ... The performance of a biological scaffold formed by the self-assembling peptide RADA16 is comparable to the most commonly used ...http://dspace.mit.edu/handle/1721.1/33396
Cellular sentinels for Heat Shock Protein-peptide complexes in vivo. (100.1) | The Journal of Immunology
HSP-chaperoned peptides are then cross-presented for priming of specific T cell responses. Our goal is to identify the subset(s ... Cellular sentinels for Heat Shock Protein-peptide complexes in vivo. (100.1) Message Subject (Your Name) has forwarded a page ... Cellular sentinels for Heat Shock Protein-peptide complexes in vivo. (100.1). Michelle Messmer and Robert Binder ...http://www.jimmunol.org/content/186/1_Supplement/100.1
Peter Thomas Roth's Deal with Serum: Benefits of Peptides on your Skin - Agosuper
Introduction to Peptides:. A peptide is usually a string of amino acids, the basic elements are used to make proteins. As ... The Significant Job Peptides Perform in Pores and skin Health and fitness:. Skin experts became fascinated with peptides after ... Sign Peptides foster balanced pores and skin in two means. 1st, particular sign peptides result in a rise in fibroblast ... Please read on to master precisely what a peptide is, and why several types of peptides are adept at reviving pores and skin. ...http://www.agosuper.com/peter-thomas-roths-deal-with-serum-benefits-of-peptides-on-your-skin/
SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture. - Oxford Neuroscience
Peptide-peptide ligation enabled covalent and site-specific polymerization of affibodies or antibodies against the tumor ... Here we develop irreversible peptide-peptide interaction, through redesign of this domain and genetic dissection into three ... However, binding to peptides is generally weak, so assemblies are unstable over time and disassemble with force or harsh ... All components expressed efficiently in Escherichia coli and peptide tags were reactive at the N terminus, at the C terminus, ...https://www.neuroscience.ox.ac.uk/publications/457920
nanoHUB.org - Resources: KIST/PU Phage Display Selection of Tissue-Specific Homing Peptides and their Theragnostic Applications...
For example, the Bld-1 peptide is specific to bladder tumor cells and the AP-1 to atherosclerotic plaques. These peptides could ... The AP-1 peptide alone or assembled with HGC nanoparticles could home to atherosclerotic plaques in LDL receptor-deficient mice ... We have demonstrated that the Bld-1 peptide can be homing to bladder tumor in vivo and showed a tumor specific PET imaging in ... These results demonstrate the potential of the homing peptide technology for affinity-based drug targeting and molecular ...http://nanohub.org/resources/3375/play
Critical self-assembly concentration of bolaamphiphilic peptides and peptide hybrids determined by fluorescence measurements
MARTARI, Marco and SANDERSON, Ronald D.. Critical self-assembly concentration of bolaamphiphilic peptides and peptide hybrids ... Novel bolaamphiphilic peptides and peptide hybrids incorporating non-natural aminoacids were designed around a model lysine/ ... of these amphiphilic peptides and peptide hybrids. Different experimental conditions were studied. The morphology of the ... Keywords : Peptide aggregation; self-assembly; critical self-assembly concentration; fluorescence; pyrene. · text in English · ...http://www.scielo.org.za/scielo.php?script=sci_abstract&pid=S0379-43502008000100010&lng=en&nrm=iso&tlng=en
Faculty Collaboration Database - DeNovoID: a web-based tool for identifying peptides from sequence and mass tags deduced from...
De novo peptide sequencing is an approach to determine partial peptide sequences for some of the unidentified spectra. A ... DeNovoID: a web-based tool for identifying peptides from sequence and mass tags deduced from de novo peptide sequencing by mass ... One of the core activities of high-throughput proteomics is the identification of peptides from mass spectra. Some peptides can ... Peptides. Proteomics. Sequence Analysis, Protein. Software. User-Computer Interface. View this publication's entry at the ...https://fcd.mcw.edu/?module=search&func=showPublication&id=42282
Patent US5668110 - Peptides and compounds that bind to the IL-5 receptor - Google Patents
Such peptides and peptide mimetics are useful in methods for treating disorders that involve improper production of or response ... as well as in diagnostic methods employing labeled peptides and peptide mimetics. ... Described are peptides and peptide mimetics that bind to and the IL-5 receptor. ... Described are peptides and peptide mimetics that bind to and the IL-5 receptor. Such peptides and peptide mimetics are useful ...http://www.google.com/patents/US5668110?dq=3798359
A peptide hormone is a peptide that acts as a hormone.. *A proteose is a mixture of peptides produced by the hydrolysis of ... Peptide classes. Peptides are divided into several classes, depending on how they are produced:. Milk peptides Two ... The term peptide has been used to mean secretagogue peptides and peptide hormones in sports doping matters: secretagogue ... Well-known peptide families. The peptide families in this section are ribosomal peptides, usually with hormonal activity ...https://en.wikipedia.org/wiki/Peptide
Resolve a DOI Name
Type or paste a DOI name into the text box. Click Go. Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to firstname.lastname@example.org. Further documentation is available here. ...http://dx.doi.org
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire | PNAS
In the example shown, peptide A, but not peptide B, can bind to the HLA molecule. Self-peptides presented to T cells in this ... Three of these peptides were present at levels (,100 copies/cell) that place them among the top 5% of all peptides in the drug- ... To set up the assay, 5 × 105 PBMCs were then exposed to 10 μg/mL of exogenous peptides, either singly or as peptide pools ... D) Abacavir binding in the F pocket does not alter the peptide conformation compared with other peptide/HLA-B complexes. A ...http://www.pnas.org/content/109/25/9959.long
Therapeutic Peptides | SpringerLink
Methods and Protocols features biological methods for the preparation of peptide phage display libraries using both filamentous ... Therapeutic Peptides: Methods and Protocols features biological methods for the preparation of peptide phage display libraries ... Heterovalent ligands Library design Peptide library mining Peptide phage display libraries Therapeutic candidates ... peptide libraries for peptides with the desired function and the subsequent characterization of the identified peptides. ...https://link.springer.com/book/10.1007/978-1-62703-673-3
Peptides as Immunogens | SpringerLink
They can take up and degrade antigens, in the case of pro- teins to peptides. The peptides of protein antigens reappear on the ... Molecular Features of Class II MHC-Restricted T-Cell Recognition of Protein and Peptide Antigens: The Importance of Amphipathic ... Immune Response to Synthetic Herpes Simplex Virus Peptides:The Feasibility of a Synthetic Vaccine ... The Value of Synthetic Peptides as Vaccines for Eliciting T-Cell Immunity ...https://link.springer.com/book/10.1007/978-3-642-71440-5
... Sebastian W. Bunka seb at i102pc1.vu-wien.ac.at Wed Nov 2 02:20:08 EST 1994 *Previous message: ...http://www.bio.net/bionet/mm/bio-soft/1994-November/009180.html
Peptide - Wikipedia
... fungal peptides, invertebrate peptides, amphibian/skin peptides, venom peptides, cancer/anticancer peptides, vaccine peptides ... cardiovascular peptides, renal peptides, respiratory peptides, opiate peptides, neurotrophic peptides, and blood-brain peptides ... immune/inflammatory peptides, brain peptides, endocrine peptides, ingestive peptides, gastrointestinal peptides, ... A peptide hormone is a peptide that acts as a hormone.. *A proteose is a mixture of peptides produced by the hydrolysis of ...https://en.wikipedia.org/wiki/Peptone
Moisturizers With Peptides | Sephora
Firming Peptide Ingredient Callouts: Free of sulfates SLS and SLES, parabens, and phthalates.. What Else You Need to Know: When ... Shopping ideas related to Moisturizers With Peptides. face creams for winter. "It's perfect to get me through the Winter." ... The key to Saturday Skin is the Cha-7 es Complex™, an exclusive peptide formula that supports the skin's natural regeneration ... A lightweight cream with advanced ceramides to deeply hydrate and a triple peptide blend to visibly smooth the appearance of ...https://www.sephora.com/buy/moisturizers-with-peptides
... is an international journal presenting original contributions on the biochemistry, physiology and pharmacology of ... Regulatory Peptides merged with Peptides in January 2015. The two journals now share a common aims and scope and a consolidated ... The most downloaded articles from Peptides in the last 90 days. * Cell-penetrating peptides for siRNA delivery to glioblastomas ... Peptides emphasizes all aspects of high profile peptide research in mammals and non-mammalian vertebrates. Special ...https://www.journals.elsevier.com/peptides