Intraperitoneal cisplatin and paclitaxel in ovarian cancer
... intravenous paclitaxel plus intraperitoneal cisplatin and paclitaxel improves survival in patients with optimally debulked ... Conclusions: As compared with intravenous paclitaxel plus cisplatin, intravenous paclitaxel plus intraperitoneal cisplatin and ... that compared intravenous paclitaxel plus cisplatin with intravenous paclitaxel plus intraperitoneal cisplatin and paclitaxel ... Intraperitoneal cisplatin and paclitaxel in ovarian cancer N Engl J Med. 2006 Jan 5;354(1):34-43. doi: 10.1056/NEJMoa052985. ...
nab-Paclitaxel mechanisms of action and delivery
Albumin-bound paclitaxel (Abraxane; nab®-Paclitaxel), a novel solvent-free taxane, has demonstrated higher response rates and ... The technology used to create nab-paclitaxel utilizes albumin to deliver paclitaxel, resulting in an advantageous ... nab-Paclitaxel mechanisms of action and delivery J Control Release. 2013 Sep 28;170(3):365-72. doi: 10.1016/j.jconrel.2013.05. ... higher tumor uptake relative to sb-paclitaxel. Another possible contributing factor to the tumor accumulation of nab-paclitaxel ...
Clinical application of airway bypass with paclitaxel-eluting stents: early results
... J Thorac Cardiovasc Surg. 2007 Oct;134(4): ... Objective: To assess the safety and early clinical results of a multicenter evaluation of airway bypass with paclitaxel-eluting ... and placement of a paclitaxel-eluting stent to expand and maintain the new passage between the airway and adjacent lung tissue ...
Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma
... at a dose of 200 mg every 3 weeks or the investigators choice of chemotherapy with paclitaxel, docetaxel, or vinflunine. The ...
Non-enrolment of ovarian cancer patients in clinical trials: reasons and background
Paclitaxel / administration & dosage * Patient Participation* * Patient Selection* * Prospective Studies * Retrospective ...
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or...
... nab-paclitaxel; paclitaxel; or gemcitabine plus carboplatin) or placebo plus chemotherapy. Randomisation was stratified by type ...
A randomized phase III trial in advanced endometrial carcinoma of surgery and volume directed radiation followed by cisplatin...
The addition of paclitaxel to cisplatin and doxorubicin following surgery and radiation was not associated with a significant ... with or without paclitaxel [P] (160 mg/m(2)). Initially in paclitaxel treated patients and, after May 2002, all patients ... Hematologic adverse events, sensory neuropathy and myalgia, were more frequent and severe in the paclitaxel arm (p,0.01) which ... Conclusion: The addition of paclitaxel to cisplatin and doxorubicin following surgery and radiation was not associated with a ...
Mielcarek P[au] - Search Results - PubMed
Paclitaxel hypersensitivity reactions in patients with advanced ovarian carcinoma]. Kobierski J, Majdak E, Mielcarek P, Emerich ...
Niazi K[au] - Search Results - PubMed
No Mortality Signal With Stellarex Low-Dose Paclitaxel DCB: ILLUMENATE Pivotal 4-Year Outcomes. Lyden SP, Faries PL, Niazi KAK ...
Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That...
Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That ... Participants were randomly assigned to receive carboplatin-paclitaxel (control arm) for six cycles with or without intravenous ... This multicenter, randomized phase II trial compared carboplatin-paclitaxel with and without trastuzumab in patients with ... Conclusion Addition of trastuzumab to carboplatin-paclitaxel was well tolerated and increased progression-free survival. These ...
![ABCC10 ATP binding cassette subfamily C member 10 [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
ABCC10 ATP binding cassette subfamily C member 10 [Homo sapiens (human)] - Gene - NCBI
the combination of paclitaxel and masitinib could serve as a novel and useful therapeutic strategy to reverse paclitaxel ... Title: Masitinib antagonizes ATP-binding cassette subfamily C member 10-mediated paclitaxel resistance: a preclinical study. ...
Weiping Tian - Search Results - PubMed
AC1MMYR2 impairs high dose paclitaxel-induced tumor metastasis by targeting miR-21/CDK5 axis. Ren Y, Zhou X, Yang JJ, Liu X, ...
RSRC2 arginine and serine rich coiled-coil 2 [Homo sapiens (human)] - Gene - NCBI
Title: TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative ... TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative ... our findings suggest that paclitaxel targets the TRA2A-RSRC2 splicing pathway, and deregulated TRA2A and RSRC2 expression may ... confer paclitaxel resistance. In addition, our study demonstrates that expression of TRA2A in conjunction with RSRC2 may ...
Axonal pruning is actively regulated by the microtubule-destabilizing protein kinesin superfamily protein 2A
Paclitaxel / pharmacology * Polymerization / drug effects * RNA Interference * RNA, Small Interfering / metabolism * Repressor ...
Clinical Queries - PubMed
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN. Ma Q, et al. ...
A Phase II Study of Pelareorep (REOLYSIN®) in Combination with Gemcitabine for Patients with Advanced Pancreatic Adenocarcinoma
FOLFIRINOX or gemcitabine in combination with nab-paclitaxel are standard treatment options for metastatic disease. However, ... FOLFIRINOX or gemcitabine in combination with nab-paclitaxel are standard treatment options for metastatic disease. However, ...
Tapani Viitala - Search Results - PubMed
Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells. ...
Wanitcha Chanloung - Search Results - PubMed
Paclitaxel-induced diffuse scleroderma with possible scleroderma-renal crisis: a case report and literature review of taxanes- ...
Peckitt C[au] - Search Results - PubMed
Rare Cancers Initiative Multicenter Randomized Phase II Trial of Cisplatin and Fluorouracil Versus Carboplatin and Paclitaxel ...
Noel M[au] - Search Results - PubMed
Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, ...
Lajos Pusztai - Search Results - PubMed
Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively ...
Takano M[au] - Search Results - PubMed
Paclitaxel Plus Carboplatin Versus Paclitaxel Plus Cisplatin in Metastatic or Recurrent Cervical Cancer: The Open-Label ...
GEO Accession viewer
Finally, XIAP knockdown sensitises cells to radiotherapy by 20%, to recombinant TRAIL by a 3-fold factor, and to paclitaxel and ...
Jessop H[au] - Search Results - PubMed
Atezolizumab in Combination With Carboplatin and Nab-Paclitaxel in Advanced Squamous NSCLC (IMpower131): Results From a ...
Shih C[au] - Search Results - PubMed
Pembrolizumab versus paclitaxel for previously treated PD-L1-positive advanced gastric or gastroesophageal junction cancer: 2- ...
Rougier P[au] - Search Results - PubMed
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro- ...
KOMATSU Y[au] - Search Results - PubMed
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro- ...
Hurvitz SA - Search Results - PubMed
A phase 2 study of everolimus combined with trastuzumab and paclitaxel in patients with HER2-overexpressing advanced breast ...
Martina Zimovjanova - Search Results - PubMed
A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as ...
Zaki A[au] - Search Results - PubMed
Effect of a MUC5AC Antibody (NPC-1C) Administered With Second-Line Gemcitabine and Nab-Paclitaxel on the Survival of Patients ...