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*  Vinorelbine Tartrate and Paclitaxel in Treating Older Patients With Advanced Non-Small Cell Lung Cancer - Full Text View -...
Paclitaxel. Vinorelbine. Vinblastine. Albumin-Bound Paclitaxel. Antineoplastic Agents, Phytogenic. Antineoplastic Agents. ... Vinorelbine Tartrate and Paclitaxel in Treating Older Patients With Advanced Non-Small Cell Lung Cancer. The recruitment status ... Drug: vinorelbine tartrate Drug: paclitaxel Procedure: quality-of-life assessment Other: questionnaire administration Phase 2 ... This phase II trial studies the side effects and how well vinorelbine tartrate and paclitaxel works in treating older patients ...
  https://clinicaltrials.gov/ct2/show/NCT00602797?recr=Open&cond=%22Carcinoma%2C+Non-Small-Cell+Lung%22&rank=11
*  S0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung Cancer - Full Text...
Paclitaxel. Albumin-Bound Paclitaxel. Carboplatin. Erlotinib Hydrochloride. Antineoplastic Agents, Phytogenic. Antineoplastic ... S0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung Cancer. This study is ... Patients receive paclitaxel IV over 3 hours and carboplatin IV over 30 minutes on day 1 and oral erlotinib hydrochloride once ... Drug Information available for: Paclitaxel Carboplatin Erlotinib hydrochloride Erlotinib Genetic and Rare Diseases Information ...
  https://clinicaltrials.gov/ct2/show/NCT00661193?term=S0709&rank=1
*  Taxus Cardium | Investor Relations | News Release
Paclitaxel) based products in the United States. Mr. Jiayue Zhang, who is the Chairman of Shanxi Taxus, and an additional ... company engaged in research and development focused on the natural resource cultivation and manufacture of paclitaxel, an anti- ...
  http://phx.corporate-ir.net/phoenix.zhtml?c=77949&p=irol-newsArticle&ID=1909379&highlight=
*  Weekly Paclitaxel Plus Carboplatin in Preoperative Treatment of Breast Cancer - Full Text View - ClinicalTrials.gov
4 cycles of neoadjuvant paclitaxel plus carboplatin. Drug: Paclitaxel, Carboplatin Paclitaxel 80 mg/m2, carboplatin AUC of 2 mg ... Paclitaxel. Albumin-Bound Paclitaxel. Carboplatin. Antineoplastic Agents, Phytogenic. Antineoplastic Agents. Tubulin Modulators ... Weekly Paclitaxel Plus Carboplatin in Preoperative Treatment of Breast Cancer. The safety and scientific validity of this study ... Paclitaxel was introduced into clinical practice in the early 1990s and has demonstrated good activity in the adjuvant and ...
  https://clinicaltrials.gov/ct2/show/NCT01203267
*  Taxine - Wikipedia
There has been a recent discovery in a molecule derived from the yew: paclitaxel. It has been proved that it functions as an ... paclitaxel, isotaxine B, taxine A), glycosides (taxicatine) and taxane derivates (taxol A, taxol B). There have been a lot of ...
  https://en.wikipedia.org/wiki/Taxine
*  Epothilone - Wikipedia
Like paclitaxel, epothilone B binds to the αβ-tubulin heterodimer subunit. Once bound, the rate of αβ-tubulin dissociation ... Epothilone B possess the same biological effects as paclitaxel both in vitro and in cultured cells. This is because they share ... Ganguly A, Yang H, Cabral F (November 2010). "Paclitaxel-dependent cell lines reveal a novel drug activity". Mol. Cancer Ther. ... Due to their better water solubility, cremophors (solubilizing agents used for paclitaxel which can affect cardiac function and ...
  https://en.wikipedia.org/wiki/Epothilone
*  Paclitaxel | SpringerLink
A Case of Albumin-Bound Paclitaxel-Induced Peripheral Neuropathy without Exacerbation]. Gan to Kagaku Ryoho 44: 517-519, No. 6 ...
  https://link.springer.com/article/10.1007/s40278-017-37379-4
*  paclitaxel (CHEBI:45863)
... has role human metabolite (CHEBI:77746) paclitaxel (CHEBI:45863) has role metabolite (CHEBI:25212) ... paclitaxel (CHEBI:45863) is a taxane diterpenoid (CHEBI:50367) paclitaxel (CHEBI:45863) is a tetracyclic diterpenoid (CHEBI: ... paclitaxel (CHEBI:45863) has functional parent baccatin III (CHEBI:32898) paclitaxel (CHEBI:45863) has role antineoplastic ... CHEBI:45863 - paclitaxel. Main. ChEBI Ontology. Automatic Xrefs. Reactions. Pathways. Models. .gridLayoutCellStructure { min- ...
  https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:45862
*  Paclitaxel total synthesis - Wikipedia
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol ... "Synthesis of Paclitaxel. 1. Synthesis of the ABC Ring of Paclitaxel by SmI2-Mediated Cyclization" Organic Letters 17 (11), 2570 ... but it also opens the way to paclitaxel derivatives not found in nature but with greater potential. The paclitaxel molecule ... Paclitaxel Total Syntheses @ SynArchive.com Taxolog for Taxol research, founded by Holto The complete Taxol story from Chemical ...
  https://en.wikipedia.org/wiki/Paclitaxel_total_synthesis
*  Cipla-Paclitaxel - Drugs.com
A list of US medications equivalent to Cipla-Paclitaxel is available on the Drugs.com website. ... Cipla-Paclitaxel is a medicine available in a number of countries worldwide. ... Ingredient matches for Cipla-Paclitaxel. Paclitaxel. Paclitaxel is reported as an ingredient of Cipla-Paclitaxel in the ... Cipla-Paclitaxel. Cipla-Paclitaxel may be available in the countries listed below. ...
  https://www.drugs.com/international/cipla-paclitaxel.html
*  Paclitaxel (taxol) - PubMed - NCBI
Paclitaxel (taxol). Rowinsky EK1, Donehower RC.. Author information. 1. Division of Pharmacology and Experimental Therapeutics ...
  https://www.ncbi.nlm.nih.gov/pubmed/7885406
*  paclitaxel (thing) by BioTech - Everything2.com
Paclitaxel is a taxoid chemotherapy drug originally extracted from the bark of the Pacific yew. It is sold under the trade name ... paclitaxel (thing). See all of paclitaxel, no other writeups in this node. ... Paclitaxel is a taxoid chemotherapy drug originally extracted from the bark of the Pacific yew. It is sold under the trade name ... Paclitaxel is given intravenously (it irritates skin and mucous membranes on contact), and is most effective against ovarian ...
  https://everything2.com/user/BioTech/writeups/paclitaxel
*  Paclitaxel
... paclitaxel) Injection should be administered under the supervision of a physician experienced in the use of cancer ... Paclitaxel is a white to off- white crystalline powder with the empirical formula C47H51NO14 and a molecular weight of 853.9. ... Paclitaxel is a natural product with antitumor activity. TAXOL is obtained via a semi-synthetic process from Taxus baccata. The ... TAXOL® (paclitaxel) Injection should be administered under the supervision of a physician experienced in the use of cancer ...
  http://www.egeneralmedical.com/rxlist00000073.html
*  Paclitaxel Protein-Bound - Chemotherapy Drugs - Chemocare
Paclitaxel Protein-bound (Abraxane) chemotherapy side effects, how it's given, how it works, precautions and self care tips for ... Paclitaxel belongs to a group of plant alkaloids known as taxanes, along with paclitaxel. Paclitaxel (protein bound) differs ... How Paclitaxel (Protein Bound) Is Given. *Paclitaxel (protein bound) is administered into a vein by intravenous (IV) injection ... Paclitaxel (protein bound) is generally given over 30 minutes.. *Paclitaxel (protein bound) is an irritant. An irritant is a ...
  http://chemocare.com/chemotherapy/drug-info/Paclitaxel-Proteinbound.aspx
*  Abitaxel (Paclitaxel) Teva
Abitaxel information about active ingredients, pharmaceutical forms and doses by Teva, Abitaxel indications, usages and related health products lists
  http://drugs-about.com/drugs-a/abitaxel.html
*  Patent US5473055 - Polymer-bound paclitaxel derivatives - Google Patents
... are endowed with antitumor activity and show improved water solubility and decreased toxicity in comparison with paclitaxel or ... of units containing the paclitaxel and paclitaxel derivatives is from 0.5 to 2, more preferably, the content of paclitaxel in ... The paclitaxel content was 4% w/w%.. EXAMPLE 7. 2',7-di(carbobenzyloxy-β-alanyl)paclitaxel. To a solution of 200 mg of ... Water soluble paclitaxel prodrugs. US20080153865 *. Oct 29, 2007. Jun 26, 2008. Pg-Txl Company, L.P.. Water soluble paclitaxel ...
  http://www.google.com/patents/US5473055?dq=6,081,786
*  Paclitaxel - Paclitaxel Manufacturer, Supplier & Exporter
... paclitaxel dealers, suppliers, traders & exporters. Listed manufacturing companies are offering wide range of paclitaxel with ... Paclitaxel Paclitaxel is a used in . It was discovered in a program at the in 1967 when and isolated it from the bark of the ... Paclitaxel Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a ... Paclitaxel Paclitaxel is now used to treat patients with lung, ovarian, breast, head and neck cancer, and advanced forms of ...
  https://www.tradeindia.com/manufacturers/paclitaxel.html
*  Paclitaxel & carboplatin - Information and support - Macmillan Cancer Support
If you or someone close to you has been diagnosed with cancer, you're not alone. Find out what to expect, get information, practical advice and support, hear from experts and read about other people's experiences.
  https://www.macmillan.org.uk/information-and-support/lung-cancer/small-cell-lung-cancer/treating/chemotherapy/drugs-and-combination-regimens/combination-chemotherapy/paclitaxel-and-carboplatin.html
*  Phase I Study of Weekly LOC-paclitaxel Injection
The goal of this clinical research study is to find the highest tolerable dose of LOC-paclitaxel when given to patients with ... 3. To measure the plasma pharmacokinetics of LOC-paclitaxel and paclitaxel derived from LOC-paclitaxel in patients receiving ... The goal of this clinical research study is to find the highest tolerable dose of LOC-paclitaxel when given to patients with ... Part I 1. To determine the recommended dose of LOC-paclitaxel as a single agent, given weekly, 5/6 weeks. 2. To determine the ...
  https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.ID2009-0432.html
*  JCI - OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity
Paclitaxel is among the most widely used anticancer drugs and is known to cause a dose-limiting peripheral neurotoxicity, the ... Here, we identified the murine solute carrier organic anion-transporting polypeptide B2 (OATP1B2) as a mediator of paclitaxel- ... Additionally, using established tests to assess acute and chronic paclitaxel-induced neurotoxicity, we found that genetic or ... Collectively, our findings reveal a pathway that explains the fundamental basis of paclitaxel-induced neurotoxicity, with ...
  https://www.jci.org/articles/view/96160/pdf
*  Paclitaxel Albumin-stabilized Nanoparticle Formulation - National Cancer Institute
This page contains brief information about paclitaxel albumin-stabilized nanoparticle formulation and a collection of links to ... Paclitaxel albumin-stabilized nanoparticle formulation is a form of paclitaxel contained in nanoparticles (very tiny particles ... This form may work better than other forms of paclitaxel and have fewer side effects. For more information about paclitaxel ... Paclitaxel albumin-stabilized nanoparticle formulation is approved to be used alone or with other drugs to treat:. *Breast ...
  https://www.cancer.gov/about-cancer/treatment/drugs/nanoparticlepaclitaxel
*  Paclitaxel protein-bound - brand name list from Drugs.com
Find information on paclitaxel protein-bound use, treatment, drug class and molecular formula. ... Lists the various brand names available for medicines containing paclitaxel protein-bound. ... paclitaxel protein-bound systemic. Brand names: Abraxane. Drug class(es): mitotic inhibitors. Paclitaxel protein-bound systemic ... Paclitaxel protein-bound. Important: The information below refers to medicines available in the United States that contain ...
  https://www.drugs.com/ingredient/paclitaxel-protein-bound.html
*  Physiologically-based modeling and interspecies prediction of paclitaxel pharmacokinetics | SpringerLink
... model to characterize the whole-body disposition of paclitaxel (formulated in Cremophor EL and ethanol-Taxol®) in mice and... ... Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with ... Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded lipid nanocapsules. Pharm Res 23(6):1243- ... Zhang W, Shi Y, Chen Y, Yu S, Hao J, Luo J, Sha X, Fang X (2010) Enhanced antitumor efficacy by paclitaxel-loaded pluronic P123 ...
  https://link.springer.com/article/10.1007%2Fs10928-018-9586-9
*  Paclitaxel-Triazine Dendrimer Constructs: Efficacy, Toxicity, and Characterization | SpringerLink
... a phase III randomized trial of paclitaxel poliglumex versus paclitaxel in chemotherapy-naive women with advanced-stage non- ... The discussion is restricted to our efforts in paclitaxel-laden constructs, an area that we have had the most success and have ... Bonomi P (2007) Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer. Expert ... El Alaoui A, Saha N, Schmidt F, Monneret C, Florent J-C (2006) New Taxol (paclitaxel) prodrugs designed for ADEPT and PMT ...
  https://link.springer.com/chapter/10.1007/978-1-4614-2305-8_5