*  Discovery of Novel Biomarkers by Text Mining: A New Avenue for Drug Research? | OMICS International
Oxo-Acid-Lyases. OMIM. 44. C0064317. KHK gene. RO. related_to. C1416630. Ketohexo-kinase. ... linoleic acid BiomarkerFor Diabetes 67.1 61 20861175, 20846914, 15284064, 7 palmitic acid BiomarkerFor Diabetes 67.1 24 ... "fatty acid metabolic process" by virtue of the internal GO relation {"fatty acid oxidation", is_a, "fatty acid metabolic ... uric acid BiomarkerFor Diabetes 61.8 259 21431449, 20002472, 20413437, 16 monoclonal antibody BiomarkerFor Obesity 61.7 41 ...
  https://www.omicsonline.org/discovery-of-novel-biomarkers-by-text-mining-a-new-avenue-for-drug-research-2155-9929.S3-004.php?aid=14884
*  KEGG T01040: CNBH0530
4.1 Carbon-carbon lyases. 4.1.1 Carboxy-lyases. 4.1.1.48 indole-3-glycerol-phosphate synthase. CNBH0530. 4.1.3 Oxo-acid-lyases ... Amino acid metabolism. 00400 Phenylalanine, tyrosine and tryptophan biosynthesis. CNBH0530. Enzymes [BR:cnb01000]. 4. Lyases. ...
  http://www.genome.jp/dbget-bin/www_bget?cnb:CNBH0530
*  KEGG ORTHOLOGY: K01656
4.1.3 Oxo-acid-lyases. 4.1.3.27 anthranilate synthase. K01656 TRP3; anthranilate synthase / indole-3-glycerol phosphate ... 4. Lyases. 4.1 Carbon-carbon lyases. 4.1.1 Carboxy-lyases. 4.1.1.48 indole-3-glycerol-phosphate synthase. K01656 TRP3; ... Nucleotide and amino acid metabolism. Aromatic amino acid metabolism. M00023 Tryptophan biosynthesis, chorismate =, tryptophan ... Amino acid metabolism. 00400 Phenylalanine, tyrosine and tryptophan biosynthesis. K01656 TRP3; anthranilate synthase / indole-3 ...
  http://www.genome.jp/dbget-bin/www_bget?ko:K01656
*  HIS7 - Imidazole glycerol phosphate synthase hisHF - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) -...
oxo-acid-lyase activity Source: InterPro. Complete GO annotation.... ,p>The ,a href="http://www.geneontology.org/">Gene ... Amino-acid biosynthesis, Histidine biosynthesis, Stress response. Enzyme and pathway databases. BioCyc Collection of Pathway/ ... This subpathway is part of the pathway L-histidine biosynthesis, which is itself part of Amino-acid biosynthesis.. View all ... By amino acid starvation. It has a GCN4-dependent and a GCN4-independent (basal) expression. ...
  http://www.uniprot.org/uniprot/P33734
*  Citryl-CoA lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... In enzymology, a citryl-CoA lyase (EC 4.1.3.34) is an enzyme that catalyzes the chemical reaction (3S)-citryl-CoA ⇌ {\ ... citryl-CoA oxaloacetate-lyase. This enzyme participates in citrate cycle (tca cycle). Dimroth P, Loyal R, Eggerer H (1977). " ... "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme- ...
  https://en.wikipedia.org/wiki/Citryl-CoA_lyase
*  Chorismate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... This enzyme belongs to the class Lyases; more specifically the ox-acid-lyase or the carbon-carbon-lyases. taxonomic lineage: ... There are several different names for chorismate lyase. it is also called chorismate pyruvate lyase (4-hydroxybenzoate-forming ... It has a mass of 18,777 daltons Its sequence is 165 amino acids long position: 35(M) position: 77(R) position: 115(L) position ...
  https://en.wikipedia.org/wiki/Chorismate_lyase
*  Methylisocitrate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... Tabuchi T; Satoh T (1976). "Distinction between isocitrate lyase and methylisocitrate lyase in Candida lipolytica". Agric. Biol ... 3-tricarboxylate pyruvate-lyase. This enzyme participates in propanoate metabolism. Methylisocitrate lyase was discovered in ... This allows catabolism of propionic acid-and, using beta oxidation, other fatty acids with odd numbers of carbons-without ...
  https://en.wikipedia.org/wiki/Methylisocitrate_lyase
*  Citrate (pro-3S)-lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... citrate lyase, citrate oxaloacetate-lyase, and citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]. This enzyme participates ... In enzymology, a citrate (pro-3S)-lyase (EC 4.1.3.6) is an enzyme that catalyzes the chemical reaction citrate ⇌ {\displaystyle ... Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA- ...
  https://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase
*  4-hydroxy-4-methyl-2-oxoglutarate aldolase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... This enzyme participates in benzoate degradation via hydroxylation and c5-branched dibasic acid metabolism. Maruyama K ( ... name of this enzyme class is 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming). Other names in common use ...
  https://en.wikipedia.org/wiki/4-hydroxy-4-methyl-2-oxoglutarate_aldolase
*  4-hydroxy-2-oxoglutarate aldolase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... 2-oxo-4-hydroxyglutaric aldolase, DL-4-hydroxy-2-ketoglutarate aldolase, hydroxyketoglutarate aldolase, 2-keto-4- ... Other names in common use include 2-oxo-4-hydroxyglutarate aldolase, hydroxyketoglutaric aldolase, 4-hydroxy-2-ketoglutaric ... hydroxybutyrate aldolase, and 4-hydroxy-2-oxoglutarate glyoxylate-lyase. This enzyme participates in arginine and proline ...
  https://en.wikipedia.org/wiki/4-hydroxy-2-oxoglutarate_aldolase
*  Citramalate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... citramalate lyase, (+)-citramalate pyruvate-lyase, citramalate pyruvate lyase, (3S)-citramalate pyruvate-lyase, and (2S)-2- ... This enzyme participates in c5-branched dibasic acid metabolism. Barker HA (1967). "Citramalate lyase of Clostridium ... "Isolation and function of the subunits of citramalate lyase and formation of hybrids with the subunits of citrate lyase". Eur. ...
  https://en.wikipedia.org/wiki/Citramalate_lyase
*  2,3-dimethylmalate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... Pirzer P, Lill U, Eggerer H (1979). "Nicotinic acid metabolism. 2,3-Dimethylmalate lyase". Hoppe-Seyler's Z. Physiol. Chem. 360 ... 3-dimethylmalate pyruvate-lyase. This enzyme participates in c5-branched dibasic acid metabolism. ... In enzymology, a 2,3-dimethylmalate lyase (EC 4.1.3.32) is an enzyme that catalyzes the chemical reaction (2R,3S)-2,3- ...
  https://en.wikipedia.org/wiki/2,3-dimethylmalate_lyase
*  4-hydroxy-2-oxovalerate aldolase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... 4-hydroxy-2-oxovalerate pyruvate-lyase, and 4-hydroxy-2-oxopentanoate pyruvate-lyase. This enzyme participates in 8 metabolic ... name of this enzyme class is 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming). Other names in common use include ...
  https://en.wikipedia.org/wiki/4-hydroxy-2-oxovalerate_aldolase
*  1-hydroxycyclohexan-1-yl)acetyl-CoA lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... acetyl-CoA cyclohexanone-lyase. Ougham HJ; Trudgill PW (1982). "Metabolism of cyclohexaneacetic acid cyclohexanebutyric acid by ... In enzymology, a (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC 4.1.3.35) is an enzyme that catalyzes the chemical reaction (1- ... name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also ...
  https://en.wikipedia.org/wiki/(1-hydroxycyclohexan-1-yl)acetyl-CoA_lyase
*  3-hydroxyaspartate aldolase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... erythro-beta-hydroxyaspartate glycine-lyase, and erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase. GIBBS RG, MORRIS JG (1964). " ... name of this enzyme class is erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming). Other names in common use ...
  https://en.wikipedia.org/wiki/3-hydroxyaspartate_aldolase
*  Oxalomalate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... In enzymology, an oxalomalate lyase (EC 4.1.3.13) is an enzyme that catalyzes the chemical reaction 3-oxalomalate ⇌ {\ ... "Glutamate biosynthesis in an organism lacking a Krebs tricarboxylic acid cycle. V. Isolation of alpha-hydroxy-gamma- ... This enzyme is also called 3-oxalomalate glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism ...
  https://en.wikipedia.org/wiki/Oxalomalate_lyase
*  Citramalyl-CoA lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... Other names in common use include citramalyl coenzyme A lyase, (+)-CMA-CoA lyase, and (3S)-citramalyl-CoA pyruvate-lyase. This ... "Isolation and function of the subunits of citramalate lyase and formation of hybrids with the subunits of citrate lyase". Eur. ... In enzymology, a citramalyl-CoA lyase (EC 4.1.3.25) is an enzyme that catalyzes the chemical reaction (3S)-citramalyl-CoA ⇌ {\ ...
  https://en.wikipedia.org/wiki/Citramalyl-CoA_lyase
*  N-acetylneuraminate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... N-acetylneuraminic lyase, N-acetylneuraminic acid lyase, NPL, NALase, NANA lyase, acetylneuraminate pyruvate-lyase, and N- ... acetylneuraminate lyase, sialic aldolase, sialic acid aldolase, sialate lyase, N-acetylneuraminic aldolase, neuraminic aldolase ... COMB DG, ROSEMAN S (1960). "The sialic acids. I. The structure and enzymatic synthesis of N-acetylneuraminic acid". J. Biol. ...
  https://en.wikipedia.org/wiki/N-acetylneuraminate_lyase
*  Isocitrate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. Other enzymes ... Shiio I, Shiio T; McFadden BA (1965). "Isocitrate lyase from Pseudomonas indigofera. I. Preparation, amino acid composition and ... threo-Ds-isocitrate glyoxylate-lyase, and isocitrate glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate ... Isocitrate lyase (EC 4.1.3.1), or ICL, is an enzyme in the glyoxylate cycle that catalyzes the cleavage of isocitrate to ...
  https://en.wikipedia.org/wiki/Isocitrate_lyase
*  3-hydroxy-3-isohexenylglutaryl-CoA lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... 3-hydroxy-3-isohexenylglutaryl coenzyme A lyase, 3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase, and 3- ... In enzymology, a 3-hydroxy-3-isohexenylglutaryl-CoA lyase (EC 4.1.3.26) is an enzyme that catalyzes the chemical reaction 3- ... THE PURIFICATION AND PROPERTIES OF BETA-ISOHEXENYLGLUTACONYL-COA-HYDRATASE AND BETA-HYDROXY-BETA-ISOHEXENYLGLUTARYL-COA-LYASE ...
  https://en.wikipedia.org/wiki/3-hydroxy-3-isohexenylglutaryl-CoA_lyase
*  Malyl-CoA lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ... Other names in common use include malyl-coenzyme A lyase, and (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase. This ... In enzymology, a malyl-CoA lyase (EC 4.1.3.24) is an enzyme that catalyzes the chemical reaction (3S)-3-carboxy-3- ... Tuboi S; Kikuchi G (1965). "Enzymic cleavage of malyl-Coenzyme A into acetyl-Coenzyme A and glyoxylic acid". Biochim. Biophys. ...
  https://en.wikipedia.org/wiki/Malyl-CoA_lyase
*  Aminodeoxychorismate lyase - Wikipedia
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. This enzyme, ... 4-amino-4-deoxychorismate lyase (EC 4.1.3.38) is an enzyme that participates in folate biosynthesis by catalyzing the ... All known examples of 4-amino-4-deoxychorismate lyase bind PLP (pyridoxal-5'-phosphate), a cofactor employed during catalysis. ... O'Rourke PEF, Eadsforth TC, Fyfe PK, Shepherd SM, Hunter WN (2011). "Pseudomonas aeruginosa 4-amino-4-deoxychorismate lyase: ...
  https://en.wikipedia.org/wiki/Aminodeoxychorismate_lyase
*  US20170211104A1 - Biosynthetic production of acetaminophen, p-aminophenol, and p-aminobenzoic acid - Google Patents
... and p-aminobenzoic acid and the purification of biologically derived acetaminophen. ... C12Y401/03-Oxo-acid-lyases (4.1.3) * C12Y401/03038-Aminodeoxychorismate lyase (4.1.3.38) ... i. chorismic acid to p-aminobenzoic acid (PABA) (pathway step a);. *ii. p-aminobenzoic acid to p-aminophenol (pathway step b); ... The enzymes that modify chorismic acid to form p-aminobenzoic acid (PABA) (pathway step a) are aminodeoxychorismate lyase and ...
  https://patents.google.com/patent/US20170211104A1/en
*  Anthranilate synthase - Wikipedia
This enzyme belongs to the family of lyases, to be specific the oxo-acid-lyases, which cleave carbon-carbon bonds. The ... chorismate lyase, and chorismate pyruvate-lyase (amino-accepting). This enzyme participates in phenylalanine, tyrosine and ... systematic name of this enzyme class is chorismate pyruvate-lyase (amino-accepting; anthranilate-forming). Other names in ...
  https://en.wikipedia.org/wiki/Anthranilate_synthase
*  RCSB PDB for 1HVA
Classification: LYASE(OXO-ACID) * Deposited: 1992-10-27 Released: 1993-10-31 ...
  http://www.rcsb.org/pdb/explore/king.do?structureId=1HVA