*  Increase of adenylate cyclase catalytic-unit activity by dexamethasone in rat osteoblast-like cells | Biochemical Journal
Increase of adenylate cyclase catalytic-unit activity by dexamethasone in rat osteoblast-like cells. R Rizzoli, V von Tscharner ... Using the osteoblast-like cell line ROS 17/2.8, which possesses receptors for both PTH and glucocorticoids, we investigated ... Thus in osteoblast-like cells dexamethasone appears to increase cyclic AMP synthesis by influencing the catalytic unit. ... Increase of adenylate cyclase catalytic-unit activity by dexamethasone in rat osteoblast-like cells ...
  http://www.biochemj.org/content/237/2/447
*  Plus it
The osteoblast differentiation induced by MDA PCa 2b cells was associated with up-regulation of the osteoblast-specific ... Osteoblast differentiation in this system was associated with up-regulation of the osteoblast-specific transcriptor factor ... Primary Cultures of Mouse Calvaria Osteoblasts.. To obtain primary culture of osteoblasts, we used newborn CD1 mice that were ... The development, differentiation, and maturation of the osteoblast phenotype in primary cultures of rat calvaria osteoblasts ...
  http://cancerres.aacrjournals.org/content/61/14/5652
*  c-Src and IL-6 inhibit osteoblast differentiation and integrat...
... and c-Src impair osteoblast maturation in vitro and in ... c-Src and IL-6 inhibit osteoblast differentiation and integrate ... We find that the IGFBP5 produced by osteoblasts stimulates osteoclastogenesis and bone resorption, acting as an osteoblast- ... a c-Src activating factor that amplifies this loop only in immature osteoblasts. In contrast, in mature osteoblasts, IGFBP5 is ... c-Src and IL-6 inhibit osteoblast differentiation and integrate IGFBP5 signalling.. Authors * Peruzzi, Barbara ...
  https://www.mysciencework.com/publication/show/c-src-il-6-inhibit-osteoblast-differentiation-integrate-igfbp5-signalling-0e08cd65
*  β-adrenergic receptor signaling regulates Ptgs2 by driving circadian gene expression in osteoblasts | Journal of Cell Science
β-AR signaling stimulated transcriptional rhythmicity in osteoblasts. To determine whether β-AR signaling in murine osteoblasts ... Per3 and Bmal1 in human osteoblasts. On the one hand, Iso induced oscillations in the osteoblast-related gene Col1a1, but not ... Osteoblasts, osteocytes and osteoclasts are involved in bone remodeling processes in mammals, and these are regulated by ... In order to determine whether β-AR signaling in osteoblasts could mediate the rhythmic expression of Ptgs2, cells were treated ...
  http://jcs.biologists.org/content/127/17/3711
*  Tenascin in bone morphogenesis: expression by osteoblasts and cell type-specific expression of splice variants | Journal of...
In primary osteoblast-enriched cultures, extracellular tenascin was found only in cell aggregates expressing the osteoblast ... Tenascin was secreted into the medium and deposited in the matrix by human and rat osteoblast-like cell lines, as well as by ... Chicken osteoblast cultures synthesized almost exclusively the largest tenascin subunit, whereas fibroblast cultures from ... Within osteogenic regions, tenascin mRNA was expressed by osteoblasts. A comparison of in situ hybridization and ...
  http://jcs.biologists.org/content/103/3/765
*  Pannexin 3 functions as an ER Ca2+ channel, hemichannel, and gap junction to promote osteoblast differentiation | JCB
Panx3 promotes osteoblast differentiation. For further elucidation of the Panx3 function during osteoblast differentiation, we ... 6 A). Akt signaling is required for osteoblast differentiation, bone formation, and prevention of osteoblast apoptosis ( ... which are progenitors for osteoblasts (arrowheads in Fig. 1 A, b). Immunostaining of osteocalcin (Ocn), an osteoblast marker, ... Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. J. Cell Biol. 172:909-921. doi:10.1083 ...
  http://jcb.rupress.org/content/193/7/1257
*  Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre...
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre- ... and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic ...
  http://scholarbank.nus.edu.sg/handle/10635/25311
*  Engineering surfaces to direct integrin binding and signaling to promote osteoblast differentiation - pdf descargar
Engineering surfaces to direct integrin binding and signaling to promote osteoblast differentiation. . Biblioteca virtual para ... Furthermore, the OH and NH2 surfaces supported elevated levels of osteoblast differentiation as evidenced by osteoblast- ... Engineering surfaces to direct integrin binding and signaling to promote osteoblast differentiation - Descarga este documento ... Engineering surfaces to direct integrin binding and signaling to promote osteoblast differentiation. ...
  http://libros.duhnnae.com/2017/jun7/149809785827-Engineering-surfaces-to-direct-integrin-binding-and-signaling-to-promote-osteoblast-differentiation.php
*  N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms | Journal of...
To determine the specific roles of these two cadherins in the adult skeleton, we generated mice with an osteoblast/osteocyte ... N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms ... N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms ... N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms ...
  http://jcs.biologists.org/content/early/2010/07/06/jcs.067777
*  Dentin Matrix Protein 1 Detection: ELISAs and Antibodies
It is thought to play a role in regulating expression of osteoblast-specific genes during osteoblast cell differentiation and ... In mature osteoblasts, the DMP1 protein is phosphorylated and localized to the extracellular matrix, where it plays a role in ... are expressed in osteoblast cells, DMP1 is expressed in osteocytes, making it a candidate biomarker for osteocyte activity. ... is localized to the nucleus in osteoblast precursor cells. ...
  http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Bone_Research/Dentin_Matrix_Protein1?sitex=10020:22372:US&PEBCL1=s0zEgcoEXY2b8DsaqwqKx8qGMj&PEBCL1_pses=ZG0EF1455C0B19156145CA03345229354D9766E0E194AD3DFEFBDBC74D1C90CE41451BD5581926506997D7CBE4F10474EF4610C83ABF337ECA
*  Cachexia
However, it is unclear whether cells of the osteoblast lineage signal back to prostate cancer cells, and if so, whether such ... In prostate cancer metastases to bone, cancer cell-derived cytokines stimulate RANKL expression by cells of the osteoblast ... In conclusion, prostate cancer cells and cells of the osteoblast lineage communicate via two inter-dependent signaling pathways ... which is known to promote RANKL expression by osteoblasts). Second, treatment of PC3 cells with IL-6 increased the expression ...
  http://flipper.diff.org/app/rules/info/7791
*  "The onset and progression of osteoblast differentiation is functionall" by Gary S. Stein, Jane B. Lian et al.
For a histone gene where down-regulation is transcriptionally mediated, we have observed that the shutdown of osteoblast ... of osteoblast differentiation is supported by the persistence of Site II-HiNF-D interactions when proliferating rat osteoblasts ... deposition and possibly organization of the osteoblast extracellular matrix. It is also reasonable to postulate that properties ... activity which occurs during the initial stages of the developmental sequence and the induction of genes encoding osteoblast ...
  http://escholarship.umassmed.edu/stein/131/
*  Loss of Runx2 in Committed Osteoblasts Impairs Postnatal Skeletogenesis - BIOQUANT OSTEO
The Runx2 transcription factor is critical for commitment to the osteoblast lineage. However, its role in committed osteoblasts ... We specifically deleted the Runx2 gene in committed osteoblasts using 2.3kb col1a-Cre transgenic mice. Surprisingly, the ... Decreased bone formation was associated with decreased gene expression of osteoblast markers and impaired collagen assembly in ... Taken together, functional deficiency of Runx2 in osteoblasts does not result in failed embryonic skeletogenesis, but disrupts ...
  https://osteo.bioquant.com/bibliography-entries/2016/4/7/loss-of-runx2-in-committed-osteoblasts-impairs-postnatal-skeletogenesis
*  Strontium can increase some osteoblasts without increasing hematopoietic stem cells. - Nuffield Department of Orthopaedics,...
Despite the changes in osteoblast numbers, no increment in the number of N-cadherin(+) osteoblasts and N-cadherin transcripts ... Manipulating osteoblast numbers results in a parallel change in HSC numbers. We tested the activity of strontium (Sr), a bone ... In vitro treatment of primary murine osteoblasts with Sr increased their ability to form bone nodules, and in vivo it increased ... Therefore, increasing the overall number and function of osteoblasts without increasing N-cadherin(+) cells is not sufficient ...
  https://www.ndorms.ox.ac.uk/publications/223518
*  Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation | JCB
Primary osteoblast cultures. Standard protocols were used to prepare primary cultures of osteoblasts and MSCs from the ... Loss of fibrillin-2 impairs osteoblast maturation. In line with the in vivo data, Fbn2-null calvarial osteoblasts (cObs) or ... Model of microfibril-mediated control of osteoblast maturation. The scheme summarizes the distinct contributions of osteoblast- ... calvarial osteoblast. LAP. latency-associated protein. LLC. large latent complex. LTBP. latent TGF-β-binding protein. µCT. ...
  http://jcb.rupress.org/content/190/6/1107.long
*  What does osteoblast mean?
Meaning of osteoblast. What does osteoblast mean? Information and translations of osteoblast in the most comprehensive ... Definition of osteoblast in the Definitions.net dictionary. ... Search for osteoblast on Amazon. *Search for osteoblast on ... Osteoblast. Osteoblasts are mononucleate cells that are responsible for bone formation; in essence, osteoblasts are specialized ... What does osteoblast mean?. Definitions for osteoblastˈɒs ti əˌblæst. Here are all the possible meanings and translations of ...
  http://www.definitions.net/definition/osteoblast
*  Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice (Journal...
Title: Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice ... Journal Article: Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in ... Moreover, peripheral blood mononuclear cells (PBMNCs) from the BMP-2-implanted mouse were then shown to include osteoblast ... of the PBMNCs isolated from the BMP-2-implanted GFP-mouse to the BMP-2-implanted nude mouse led to GFP-positive osteoblast ...
  https://www.osti.gov/scitech/biblio/20979828
*  Dual function of Bmpr1a signaling in restricting preosteoblast proliferation and stimulating osteoblast activity in the mouse -...
Besides increasing osteoblast number in the trabecular bone, deletion of Bmpr1a by Dmp1-Cre also notably reduced osteoblast ... The impairment in osteoblast activity correlated with reduced mTORC1 signaling in vivo, whereas inhibition of mTORC1 activity ... Dual function of Bmpr1a signaling in restricting preosteoblast proliferation and stimulating osteoblast activity in the mouse ... By deleting the receptor Bmpr1a in osteoblast-lineage cells with Dmp1-Cre, we observed a dramatic increase in trabecular bone ...
  https://osteo.bioquant.com/bibliography-entries/2016/4/7/dual-function-of-bmpr1a-signaling-in-restricting-preosteoblast-proliferation-and-stimulating-osteoblast-activity-in-the-mouse
*  Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I |...
Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I. S ... Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I ... Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I ... Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I ...
  http://www.biochemj.org/content/294/1/271
*  Osteoblasts Are Bone Idle Without Frizzled-9 - Redorbit
Fzd9-null osteoblasts differentiated normally, but they failed to mineralize their extracellular matrix. The loss of Fzd9 ... Adult bones are maintained by a balance of bone-forming osteoblasts and bone-resorbing osteoclasts. Although Wnt signaling ... A team of researchers led by Thorsten Schinke found that the Wnt receptor Fzd9 was upregulated during osteoblast ... Though little is known about Isg15's function, restoring its expression in Fzd9-null osteoblasts boosted matrix mineralization ...
  http://www.redorbit.com/news/health/2011952/osteoblasts_are_bone_idle_without_frizzled9/
*  WikiGenes - Osteoblasts
Analytical, diagnostic and therapeutic context of Osteoblasts. *The cells were identified as functional osteoblasts by indirect ... Anatomical context of Osteoblasts. *Although immature osteoblasts, which expressed alkaline phophatase weakly but not ... Gene context of Osteoblasts. *Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation [25]. ... ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Yang, X., ...
  https://www.wikigenes.org/e/mesh/e/2515.html
*  Bone voyage-Osteoblasts remotely control tumors | Science
Tumor-driven systemic activation of osteoblasts in the bone promotes lung tumor growth ... Tumor-driven systemic activation of osteoblasts in the bone promotes lung tumor growth ... report that osteoblasts, which reside in the bone, can be remotely activated by secreted factors from lung adenocarcinoma, ...
  http://science.sciencemag.org/content/358/6367/1127
*  Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway
... Ling-juan Liu,1 Li-qun Liu,1 Tao Bo,1 Shi-jun Li,1 ... J. M. Hock, V. Krishnan, J. E. Onyia et al., "Osteoblast apoptosis and bone turnover," Journal of Bone and Mineral Research, ... H. Xie, L. Q. Yuan, X. H. Luo et al., "Apelin suppresses apoptosis of human osteoblasts," Apoptosis, vol. 12, no. 1, pp. 247- ... N. Maruotti, A. Corrado, A. Neve, and F. P. Cantatore, "Bisphosphonates: effects on osteoblast," European Journal of Clinical ...
  https://www.hindawi.com/journals/ije/2013/786574/ref/
*  Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway
... the role of puerarin on osteoblast apoptosis and its underlying mechanism of action are still unclear. As we know osteoblasts ... Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway. Ling-juan Liu,1 Li-qun Liu,1 Tao Bo,1 Shi-jun Li,1 ... J. M. Hock, V. Krishnan, J. E. Onyia et al., "Osteoblast apoptosis and bone turnover," Journal of Bone and Mineral Research, ... suggesting that puerarin might regulate osteoblast proliferation and differentiation to promote bone formation in osteoblast ...
  https://www.hindawi.com/journals/ije/2013/786574/
*  Osteoblasts | OMICS Publishing Group | Endocrinology And Metabolic Syndrome
Human cultured female osteoblasts (Obs) respond age-dependently to estradiol-17β (E2) and to phytoestrogens by increased DNA ... Osteoblasts. Human cultured female osteoblasts (Obs) respond age-dependently to estradiol-17β (E2) and to phytoestrogens by ...
  https://www.omicsonline.org/endocrinology-metabolic-syndrome/osteoblasts.php